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 SO many things that I cannot possibly list them all. But this is to summarize:
lack of sleep
being hungry
crying children
homework
Donald Trump
headaches
hot coffee
mold
tests
quizzes
research papers
when Netflix WON'T LOAD
REALLY LONG AND UNNECESSARY SPACES
Click me to go back to the top and start all over again!


Please email to<EMAIL_ADDRESS>for any questions but no agent/third party!..
Also, please put your company name, your name or your title and subject on the email subject line and I will reply you with my real email address as soon as I can.
My resume is availabe upon request.
Note: I do have a lot spam emails.
Thank you.


 Bad enough knowing they modified Elmo in Grouchland's original format.  Bad enough knowing they modified Elmo in Grouchland's original format. Must they rub it in?
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Sir Richard Branson –
The Interview
How much money did you start Virgin Records with and how old were you when it made its first million?
Well I started Student with £100 that my mother gave us after she found a necklace on the road near Shamley Green. After three months of no one claiming it from the police station they told her she could have it. She knew we had no money so came up to London, sold it for £100 and gave it to us.A few years later when we decided to open a recording studio I financed it with a bank note which was a gift from my parents and a loan from Auntie Clare. Our first Virgin artist was Mike Oldfield, who recorded ‘Tubular Bells’ which was released in 1973. This album went on to sell over 5 million copies…that is when Virgin made its first million.
In the old days there seemed to be a lot of sex, drugs and rock’n’roll, how did you manage to run a business at the same time?
My generation have been known to experiment but as I have been running my own business since the age of 15 and always had to get up early in the morning, I have not let myself go with excess alcohol or drugs. Okay, alcohol occasionally!
In the old days there seemed to be a lot of sex, drugs and rock’n’roll, how did you manage to run a business at the same time?
My generation have been known to experiment but as I have been running my own business since the age of 15 and always had to get up early in the morning, I have not let myself go with excess alcohol or drugs. Okay, alcohol occasionally!
You are a big advocate of philanthropy and you use your wealth to do work which helps many of the world's poorest people. But do you see the rising inequality in our society as a problem? If so, can we rely on the generosity of the super-rich, or should other actions be taken to help close that gap? If the latter, what would your solution be?
From my very first day as an entrepreneur, I've felt the only mission worth pursuing in business is to make people's lives better. An important priority for me is a business must get their own house in order. Be or become
an agent of positive change in your own enterprise and adopt responsible practices to eliminate the risks that often lie at the root of inequality and poverty.
Rob Kim / GettyThat's why I started Student Magazine at the height of the Vietnam War, to give a voice to my generation who were against the war. It's also why we've been disrupting the airline business for more
than 30 years, and why we continue to bring change to many other industries, from mobile communications to hotels and, soon, space travel.We must also continue to push ourselves forward to improve lives for people across
the planet and I believe business can be a driving force for social, environmental and economic benefit..
You talk a lot about a management technique that you practice called, "The Walkabout", or in the US, "Managing by walking around." Tell me how that works.
Well, look, I think that in this day and age, I like to think I practiced it all my life, but I think in this day and age, it is very easy to be out and about and not stuck behind a desk. And you're going to learn so much more. I mean, if I'm on one of our airlines, I will make a point of getting out and talking to a lot of staff, talking to as many of the customers as possible, having a notebook in my back pocket, listening. And I think, one of the key attributes to a good leader is listening, making sure that you write down the feedback that you get. And very importantly, make sure you act on that feedback when you get back to base. An exceptional company is the one that gets all the little details right. And the people out on the front line, they know when things are not going right and they know when things need to be improved. And if you listen to them you can soon improve all those niggly things which turns an average company into an exceptional company.
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Your website should be so simple, a grad student could use it.
You can't test that. I'll do it for you.
I'll get very drunk, sign up for grad school, and then review your website. I'll send you my screencast; you'll get a video of me, as a new user, and as a designer trying to keep it together. And you'll get a video the morning after (more or less) - so I can recap what I might have messed up when drunk and trying to envision my live as a xenobotanist, and apologize.
I am a UX professional and full stack developer. I've been doing this for a long time. Here is my website, my github, and my twitter.
One of the core tenets of UX is that you've got to design like "the user has no fucks left to give." I can't think of a better example of this than a grad student. Any feature of your site has to be able to be used by someone who could be a grad student - because, invariably, the user will mess it up otherwise. Wonderful idea. The thing is, it is hard to test.
I and a lot of beer and poor exam results will test this for you.
Sponsors:
- Burnt Fen Creative: I make stuff.
Press:
- No one has written about us... yet.
FAQ:
• Will you actually do this? Yes.
• Can I pay you more to choose what you study? Very yes.
• Will you post your screencasts publicly? Yes.
• Is this your only job? I'm a grad student. I have no time for jobs.
• Did you set up the user is my mom too? Yes! Check it out.
• Did you.. did you just make this? Like, tonight? Yes.
I also review websites from a UX perspective while drunk, sober, and with my mom. If you're interested in that, get in touch.
Think of me like a user, but with a large knowledgebase on best practices, and no legal liability for your company. Actually, speaking of liability: I will ensure that I learn responsibly. I take all blame if I accidentally do. I will ensure that I do not endanger anyone else in the process. You waive all responsibility for me upon payment. If you are concerned about me, please contact me. If you or your loved ones struggles with grad school, talk to your doctor. Various types of therapy with real trained and certified therapists have good success rates backed by actual scientific evidence, as do certain prescription drugs. Combining them likely has an even better success rate. Learn responsibly.


Connections eye Classic campaign with Albigna
by Press AssociationAlbigna is in her winter quarters as connections dream of Classic glory in one of the major European 1000 Guineas prizes next spring.
The Jessica Harrington-trained filly ended her juvenile campaign as one of the best of her generation, with victory in the Group Two Airlie Stud Stakes at the Curragh and the Group One Prix Marcel Boussac at Longchamp.
She then signed off for 2019 with a highly-creditable fourth in the Breeders' Cup Juvenile Fillies' Turf at Santa Anita.
"She travelled home very well and is in good form, enjoying a little break," said Alan Cooper, racing manager to owners the Niarchos family.
"At this early stage we'd be looking at one of the early-season Classics - Newmarket, the Curragh, and possibly Longchamp, where she knows the course and distance.
"We're many months from all of that, but that would be the thought - having chatted with Jessie about it in Santa Anita.
"It's much too early to talk about prep races.
"She ran a very good race at Santa Anita. She was unbalanced on the first turn, which cost her some ground, and she finished beautifully."
Cooper is also looking forward to seeing how Highest Ground shapes as a three-year-old, after winning his only start as a juvenile in good style over seven furlongs at Leicester in September.
A son of Frankel, Highest Ground is in the care of Sir Michael Stoute.
"He won his maiden very well, and we look forward to him next spring," said Cooper.
"The female family is more a mile than a mile and a quarter, a mile and a half. Let's see how he winters and see what Sir Michael would like to do in the spring."


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There is no data visualization available. Please proceed to the metric definition to fix this issue.


Screen Borders
The door section was a bit more intense than originally expected. Luckly for you, this section of the tutorial has no code for you to write. I just wanted to present you with an alternate way to use doors. There are of course many more ways to use them, not just the one we have already seen and the one we're about to see. I encourage you to think about and play with door mechanics.
The legend of zelda actually uses two different types of doors. Real doors and hidden doors. A real door looks like this:
Notice how link is standing right in the doorway. If he moves just one more pixel down he will leave the house. This is similar to how we handled door interaction.
In outdoor environments however, hidden doors are used. Take a look at this picture:
Link is just standing on the edge of the screen. If that was a door tile, the entire screen would already be transitioning. Instead, link has to walk down one more tile to trigger the screen transition. Here that is in action:
So how is this done? The simple answer is that there are door tiles outside of the render area! When link walks off-screen instead of the game breaking because there not being any more tiles to check for collision against, there are hidden tiles off-screen. These tiles are collided with, colliding with a door tile causes a screen trnasition.
Here is an example of what the hidden tiles might look like:
The legend of zelda is unique in that the world doesn't scroll. At the edge of every screen is a hidden door or 7. Other games, like Final Fantasy do scroll with the player. They don't need any hidden doors. We will discuss how to scroll the world with the player later.


[gecode-users] [icl] 'map::_add' ignores default-constructed value
Filip Konvička
filip.konvicka at logis.cz
Thu Oct 29 15:26:26 CET 2015
Sorry, wrong list again :(
I apologize, this was intended for boost.users.
Filip
> Hi,
>
> First of all thanks very much for the ICL!
>
> I'm using a boost::icl::interval_map with my own value type (struct V)
> and I have a custom value combining logic by passing
> boost::icl::inplace_et to the map and defining my own "operator&=" that
> provides the logic implementation.
>
> Now what happens is that my map ignores "m += make_pair(..., V())"
> because the default-constructed value is considered neutral due to:
>
> boost/icl/interval_base_map.hpp:
>
> ... interval_base_map<...>::_add(const segment_type& addend) {
> typedef typename on_absorbtion<type,Combiner,
> absorbs_identities<type>::value>::type on_absorbtion_;
> ...
> const codomain_type& co_val = addend.second;
> if(on_absorbtion_::is_absorbable(co_val))
> return this->_map.end();
>
> This 'if' returns without actually modifying the map. Is there some
> public API that I can use to tell my map that it should not consider any
> value 'absorbable'? And is it a good idea to change this?
>
> Thank you,
> Filip
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Caglio
28-Mar-19 01:11 PM
Cos I never traded before
When you try to sell kmd, and then later to rebuy it
u send money on lets say binance
and trade komodo to what ?
I guess is BTC I just want someone to tell me thats right, cos never before I traded. I would just buy and hold, and I want to take this 27k satoshiees now, and make you all rich when it comes to 35k ( :


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Pgpool-II started its life as a personal project by Tatsuo Ishii. In the project it was just a simple connection pooling software. So the name Pgpool came from the fact. The first version was in public in 2003.
In 2004, Pgpool 1.0 was released with the native replication feature (SQL statement based replication). In the same year 2.0 was released with load balancing, and support for version 3 frontend/backend protocol. In 2005, automated fail over and master slave mode support were added.
In 2006, Pgpool became Pgpool-II. The first release 1.0 eliminated many of restrictions in Pgpool, for example the number of PostgreSQL servers was up to 2 in Pgpool. Also many new features such as parallel query mode and PCP commands (PCP stands for "Pgpool Control Protocol") were added. Probably the most important change made between Pgpool and Pgpool-II was that the project was changed from a personal project to a group project owned by the Pgpool Developement Group.


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TBM TUMOR CLASSIFIER: A SKIN-CANCER PREVENTIVE TOOL TO DETECT CANCER'S MALIGNANCY
CANCER IS LIKE THE IMPERIAL ARMY OF STAR WARS, EARLY DETECTION GETS HUMANITY ONE STEP CLOSER TO THE LIGHT SIDE OF THE FORCE
Doctor's lack of methods to detect cancer at early stages, as in many cases patients already present symptoms of advanced cancer stages. Furthermore, some of the most common used methods to diagnose cancer, including X-rays or NMR emit radiation, which are highly damaging for patients. This novel tools allows users to obtain a quick prognosis of whether they have a benign or a malignant mole on their skin.


Put it - right on you
I'll do it if you want me to
Can I put it?
I put the finger on you
I hit the spot


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During this lab, we will acquaint ourselves with the software package BLAST. Your objectives are:
Familiarize yourself with the software, how to execute it, how to visualize results.
Regarding your dataset, tell me how some of these genes are related to their homologous copies.
Step 1: Launch an instance on Jetstream. For this exercise, we will use a m1.medium instance.
ssh -i $HOME/jetkey<EMAIL_ADDRESS>The machine you are using is Linux Ubuntu: Ubuntu is an operating system you can use (I do) on your laptop or desktop. One of the nice things about this OS is the ability to update the software, easily. The command sudo apt-get update
checks a server for updates to existing software.
sudo apt-get update
The upgrade command actually installs any of the required updates.
sudo apt-get -y upgrade
OK, what are these commands? sudo
is the command that tells the computer that we have admin privileges. Try running the commands without the sudo – it will complain that you don’t have admin privileges or something like that. Careful here, using sudo means that you can do something really bad to your own computer – like delete everything, so use with caution. It’s not a big worry when using Jetstream, as this is a virtual machine- fixing your worst mistake is as easy as just terminating the instance and restarting.
So now that we have updates the software, lets see how to add new software. Same basic command, but instead of the update
or upgrade
command, we’re using install
. EASY!!
sudo apt-get -y install build-essential python3 gdebi-core r-base git libssl-dev
Install Conda. Conda is another package manager, but for scientific software. We will use it basically every week!
mkdir anaconda
cd anaconda
curl -LO https://repo.anaconda.com/archive/Anaconda3-2020.11-Linux-x86_64.sh
bash Anaconda3-2020.11-Linux-x86_64.sh -b -p $HOME/anaconda/install/
echo ". $HOME/anaconda/install/etc/profile.d/conda.sh" >> ~/.bashrc
source ~/.bashrc
Make a conda environment, activate it, and install BLAST.
conda create -y --name gen711
conda activate gen711
conda install -y -c bioconda blast
To get a feel for the different options, type blastp -help
. Which type of blast does this correspond to? Look at the help info for blastp and tblastx. There are A LOT of options, most of which you will be able to safely ignore. One of the challenges of bioinformatics is knowing about the options and which ones you can safely ignore, and which ones are important.
You have just returned from South America, where you captured a rare - never been seen before - desert mouse. You are interested in knowing how it survives, and start by trying to identify the Sodium transport genes, in particular a gene called Scn5a (https://en.wikipedia.org/wiki/Nav1.5). You’ve just had the animals’ transcriptome sequenced, and are about to begin the search!! You could use web blast like you’ve done in the past, but there are 20166 new sequences that you need to search and that would take a loooooooong time. Download the data that you just generated, using this command:
cd $HOME
curl -LO https://s3.amazonaws.com/macmanes_share/transcripts.fasta
You know that the model organism, the lab mouse, has an excellent genome, and is probably closely related to the mystery mouse, You decide to use it to help identify the sodium transport genes in the new animal. Download the data:
curl -LO ftp://ftp.ensembl.org/pub/release-85/fasta/mus_musculus/cdna/Mus_musculus.GRCm38.cdna.all.fa.gz
gzip -d Mus_musculus.GRCm38.cdna.all.fa.gz
1st step is to make the blast database
makeblastdb -in Mus_musculus.GRCm38.cdna.all.fa -out mus -dbtype nucl
Now blast.. your results should be saved in a file called blast.out
blastn -db mus -max_target_seqs 1 -query transcripts.fasta -outfmt '6 qseqid qlen length pident gaps evalue stitle' -evalue 1e-10 -num_threads 6 -out blast.out
look at blast.out
. the 1st column is the ID of the desert mouse transcript, the 2nd column is the e-value (a statistic related to how good the match between query and reference sequences is - smaller numbers better. The 3rd column is the Mouse transcript match descriptor)
less -S blast.out
# type `q` to get out of this screen.
 There are 16501 lines in that file, how are we going to find the Scn5a gene that we are looking for?? Meet grep
.
grep -i SCN5A blast.out
Download and install RStudio
curl -LO https://download2.rstudio.org/server/bionic/amd64/rstudio-server-1.4.1103-amd64.deb
sudo gdebi -n rstudio-server-1.4.1103-amd64.deb
Find out the web address of your server. Paste the web address that comes up on the terminal, in to your browser.
printf "\n\n\nMy RStudio Web server is running at: http://$(curl ifconfig.me):8787/\n\n\n"
Make a password (make it an easy one!!!)
sudo passwd $(whoami)
Note that the text will not echo to the screen (because it’s a password!) Return to the browser login page and enter your new password. Note this will not change the global XSEDE login info (i.e. it only affects this instance). Once R is up and running, we’ll give you a quick tour of the RStudio Web interface for those of you who haven’t seen it.
Install packages and read in the results file you just made.
install.packages(c("readr", "beanplot"))
library("readr")
library("beanplot")
blast <- read_delim("~/blast.out", "\t",
escape_double = FALSE, col_names = FALSE,
trim_ws = TRUE)
View(blast)
look at the results!!!
par(mfrow = c(2,2))
barplot(mean(blast$X3/blast$X2), main='A barplot', ylab="Percent Aligned")
boxplot(blast$X3/blast$X2, frame.plot=F, main='A boxplot', ylab="Percent Aligned")
beanplot(blast$X3/blast$X2, ll = 0, beanlinewd=-1, frame.plot=F, col="blue", main='A violin plot', ylab="Percent Aligned")
plot(blast$X3/blast$X2 ~ blast$X6, xlim=c(7e-11, 0), col='red',frame.plot=F, ylab="Percent Aligned", xlab='evalue', main="Evalue vs Percent Aligned")
This lab uses code from ANGUS2017: https://angus.readthedocs.io/en/2017/visualizing-blast-scores-with-RStudio.html


Lost Christmas
Lost Christmas is a movie starring Eddie Izzard, Larry Mills, and Jason Flemyng. Orphaned the previous Christmas young Goose looks after his demented grandma, selling stolen goods to soft-hearted fence Frank on his Manchester...


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