Chapter 2 Experiment 1
2.1 Procedure
This arm of the project is the linearity study. In this study three organisms will be used: Staphylococcus aureus, Pseudomonas aeruginosa, Aspergillus brasiliensis at 5 different inoculum levels. This procedure is to be performed over a period of two days.
Day 1:
- Streak colony from culture plate onto agar slope
- Incubate agar slope overnight
Day 2:
- Add glass beads to the inoculated agar slope
- Add 10ml saline to the inoculated slope
- Invert the slope a few times
- Vortex the slope for 1 minute
- Dispense 0.1ml of stock solution in 9.9ml 0.9% saline = 105
- Dispense 0.1ml of 105 dilution in 9.9ml of 0.9% saline = 103
- Dispense 2.0ml of 105 dilution in 8.0ml of 0.9% saline = 500cfu
- Dispense 1.0ml of 103 dilution in 9.0ml of 0.9% saline = 102
- Dispense 1.0ml of 500cfu dilution in 9.0ml of 0.9% saline = 50cfu
- Dispense 1.0ml of 50cfu dilution in 9.0ml of 0.9% saline = 5cfu
- Dispense 0.1ml 102 dilution in 9.9ml of 0.9% saline = 1cfu
The dilutions outlined in bold are the ones to be used in this study.
Streak 0.1ml of selected dilutions onto 10 settle plates and 10 settle plates per dilution and incubate at 30-35°C for 5 days.
Once the incubation period is complete, the plates will be read by two technicians - without marking with a pen and by both plate readers.
2.2 Staphylococcus aureus Settle Plates:
1) Analyst 1 compared to Analyst 2 :
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 7
## Minimum value for average measures: 1
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: 0
## Point estimate of bias as proportion of lowest average: 0
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 26
## Minimum value for average measures: 10
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -1
##
## Bias: 0
## Standard deviation of bias: 0.4714045
##
## Standard error of bias: 0.1490712
## Standard error for limits of agreement: 0.2639084
##
## Bias: 0
## Bias- upper 95% CI: 0.3372225
## Bias- lower 95% CI: -0.3372225
##
## Upper limit of agreement: 0.9239529
## Upper LOA- upper 95% CI: 1.520955
## Upper LOA- lower 95% CI: 0.3269506
##
## Lower limit of agreement: -0.9239529
## Lower LOA- upper 95% CI: -0.3269506
## Lower LOA- lower 95% CI: -1.520955
##
## Derived measures:
## Mean of differences/means: 0.06227296
## Point estimate of bias as proportion of lowest average: 0
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 1.847906
## Bias as proportion of LoA spread: 0
##
## Bias:
## 0 ( -0.3372225 to 0.3372225 )
## ULoA:
## 0.9239529 ( 0.3269506 to 1.520955 )
## LLoA:
## -0.9239529 ( -1.520955 to -0.3269506 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 77
## Minimum value for average measures: 41
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: 0
## Point estimate of bias as proportion of lowest average: 0
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 182.5
## Minimum value for average measures: 85.5
## Maximum value for difference in measures: 37
## Minimum value for difference in measures: -31
##
## Bias: 8.5
## Standard deviation of bias: 20.86065
##
## Standard error of bias: 6.596716
## Standard error for limits of agreement: 11.67851
##
## Bias: 8.5
## Bias- upper 95% CI: 23.42281
## Bias- lower 95% CI: -6.422809
##
## Upper limit of agreement: 49.38687
## Upper LOA- upper 95% CI: 75.80549
## Upper LOA- lower 95% CI: 22.96826
##
## Lower limit of agreement: -32.38687
## Lower LOA- upper 95% CI: -5.968257
## Lower LOA- lower 95% CI: -58.80549
##
## Derived measures:
## Mean of differences/means: 6.566413
## Point estimate of bias as proportion of lowest average: 9.94152
## Point estimate of bias as proportion of highest average 4.657534
## Spread of data between lower and upper LoAs: 81.77374
## Bias as proportion of LoA spread: 10.39453
##
## Bias:
## 8.5 ( -6.422809 to 23.42281 )
## ULoA:
## 49.38687 ( 22.96826 to 75.80549 )
## LLoA:
## -32.38687 ( -58.80549 to -5.968257 )
2) Analyst 1 compared to Biospot :
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 7
## Minimum value for average measures: 1
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: 0
##
## Bias: 0.1
## Standard deviation of bias: 0.3162278
##
## Standard error of bias: 0.1
## Standard error for limits of agreement: 0.1770351
##
## Bias: 0.1
## Bias- upper 95% CI: 0.3262157
## Bias- lower 95% CI: -0.1262157
##
## Upper limit of agreement: 0.7198064
## Upper LOA- upper 95% CI: 1.120288
## Upper LOA- lower 95% CI: 0.3193251
##
## Lower limit of agreement: -0.5198064
## Lower LOA- upper 95% CI: -0.1193251
## Lower LOA- lower 95% CI: -0.9202877
##
## Derived measures:
## Mean of differences/means: 4
## Point estimate of bias as proportion of lowest average: 10
## Point estimate of bias as proportion of highest average 1.428571
## Spread of data between lower and upper LoAs: 1.239613
## Bias as proportion of LoA spread: 8.067035
##
## Bias:
## 0.1 ( -0.1262157 to 0.3262157 )
## ULoA:
## 0.7198064 ( 0.3193251 to 1.120288 )
## LLoA:
## -0.5198064 ( -0.9202877 to -0.1193251 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 27
## Minimum value for average measures: 10.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -2
##
## Bias: -1.5
## Standard deviation of bias: 0.5270463
##
## Standard error of bias: 0.1666667
## Standard error for limits of agreement: 0.2950586
##
## Bias: -1.5
## Bias- upper 95% CI: -1.122974
## Bias- lower 95% CI: -1.877026
##
## Upper limit of agreement: -0.4669893
## Upper LOA- upper 95% CI: 0.2004795
## Upper LOA- lower 95% CI: -1.134458
##
## Lower limit of agreement: -2.533011
## Lower LOA- upper 95% CI: -1.865542
## Lower LOA- lower 95% CI: -3.20048
##
## Derived measures:
## Mean of differences/means: -8.045815
## Point estimate of bias as proportion of lowest average: -14.28571
## Point estimate of bias as proportion of highest average -5.555556
## Spread of data between lower and upper LoAs: 2.066021
## Bias as proportion of LoA spread: -72.60331
##
## Bias:
## -1.5 ( -1.877026 to -1.122974 )
## ULoA:
## -0.4669893 ( -1.134458 to 0.2004795 )
## LLoA:
## -2.533011 ( -3.20048 to -1.865542 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 79.5
## Minimum value for average measures: 42
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -6
##
## Bias: -2.3
## Standard deviation of bias: 2.58414
##
## Standard error of bias: 0.8171767
## Standard error for limits of agreement: 1.44669
##
## Bias: -2.3
## Bias- upper 95% CI: -0.4514178
## Bias- lower 95% CI: -4.148582
##
## Upper limit of agreement: 2.764914
## Upper LOA- upper 95% CI: 6.037554
## Upper LOA- lower 95% CI: -0.5077261
##
## Lower limit of agreement: -7.364914
## Lower LOA- upper 95% CI: -4.092274
## Lower LOA- lower 95% CI: -10.63755
##
## Derived measures:
## Mean of differences/means: -3.19665
## Point estimate of bias as proportion of lowest average: -5.47619
## Point estimate of bias as proportion of highest average -2.893082
## Spread of data between lower and upper LoAs: 10.12983
## Bias as proportion of LoA spread: -22.70522
##
## Bias:
## -2.3 ( -4.148582 to -0.4514178 )
## ULoA:
## 2.764914 ( -0.5077261 to 6.037554 )
## LLoA:
## -7.364914 ( -10.63755 to -4.092274 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 213.5
## Minimum value for average measures: 87
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -51
##
## Bias: -19
## Standard deviation of bias: 16.17955
##
## Standard error of bias: 5.116422
## Standard error for limits of agreement: 9.057865
##
## Bias: -19
## Bias- upper 95% CI: -7.425849
## Bias- lower 95% CI: -30.57415
##
## Upper limit of agreement: 12.71191
## Upper LOA- upper 95% CI: 33.20223
## Upper LOA- lower 95% CI: -7.7784
##
## Lower limit of agreement: -50.71191
## Lower LOA- upper 95% CI: -30.2216
## Lower LOA- lower 95% CI: -71.20223
##
## Derived measures:
## Mean of differences/means: -13.10669
## Point estimate of bias as proportion of lowest average: -21.83908
## Point estimate of bias as proportion of highest average -8.899297
## Spread of data between lower and upper LoAs: 63.42383
## Bias as proportion of LoA spread: -29.95719
##
## Bias:
## -19 ( -30.57415 to -7.425849 )
## ULoA:
## 12.71191 ( -7.7784 to 33.20223 )
## LLoA:
## -50.71191 ( -71.20223 to -30.2216 )
3) Analyst 1 compared to AutoCol :
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -2
##
## Bias: -0.2
## Standard deviation of bias: 0.6324555
##
## Standard error of bias: 0.2
## Standard error for limits of agreement: 0.3540703
##
## Bias: -0.2
## Bias- upper 95% CI: 0.2524314
## Bias- lower 95% CI: -0.6524314
##
## Upper limit of agreement: 1.039613
## Upper LOA- upper 95% CI: 1.840575
## Upper LOA- lower 95% CI: 0.2386503
##
## Lower limit of agreement: -1.439613
## Lower LOA- upper 95% CI: -0.6386503
## Lower LOA- lower 95% CI: -2.240575
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: -Inf
## Point estimate of bias as proportion of highest average -6.666667
## Spread of data between lower and upper LoAs: 2.479226
## Bias as proportion of LoA spread: -8.067035
##
## Bias:
## -0.2 ( -0.6524314 to 0.2524314 )
## ULoA:
## 1.039613 ( 0.2386503 to 1.840575 )
## LLoA:
## -1.439613 ( -2.240575 to -0.6386503 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 6
## Minimum value for average measures: 1
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -1
##
## Bias: 0.3
## Standard deviation of bias: 0.8232726
##
## Standard error of bias: 0.2603417
## Standard error for limits of agreement: 0.4608962
##
## Bias: 0.3
## Bias- upper 95% CI: 0.8889337
## Bias- lower 95% CI: -0.2889337
##
## Upper limit of agreement: 1.913614
## Upper LOA- upper 95% CI: 2.956234
## Upper LOA- lower 95% CI: 0.8709947
##
## Lower limit of agreement: -1.313614
## Lower LOA- upper 95% CI: -0.2709947
## Lower LOA- lower 95% CI: -2.356234
##
## Derived measures:
## Mean of differences/means: 2.888889
## Point estimate of bias as proportion of lowest average: 30
## Point estimate of bias as proportion of highest average 5
## Spread of data between lower and upper LoAs: 3.227229
## Bias as proportion of LoA spread: 9.295902
##
## Bias:
## 0.3 ( -0.2889337 to 0.8889337 )
## ULoA:
## 1.913614 ( 0.8709947 to 2.956234 )
## LLoA:
## -1.313614 ( -2.356234 to -0.2709947 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 38
## Minimum value for average measures: 15.5
## Maximum value for difference in measures: -6
## Minimum value for difference in measures: -30
##
## Bias: -18.4
## Standard deviation of bias: 8.553102
##
## Standard error of bias: 2.704728
## Standard error for limits of agreement: 4.788319
##
## Bias: -18.4
## Bias- upper 95% CI: -12.28148
## Bias- lower 95% CI: -24.51852
##
## Upper limit of agreement: -1.63592
## Upper LOA- upper 95% CI: 9.196011
## Upper LOA- lower 95% CI: -12.46785
##
## Lower limit of agreement: -35.16408
## Lower LOA- upper 95% CI: -24.33215
## Lower LOA- lower 95% CI: -45.99601
##
## Derived measures:
## Mean of differences/means: -65.745
## Point estimate of bias as proportion of lowest average: -118.7097
## Point estimate of bias as proportion of highest average -48.42105
## Spread of data between lower and upper LoAs: 33.52816
## Bias as proportion of LoA spread: -54.87924
##
## Bias:
## -18.4 ( -24.51852 to -12.28148 )
## ULoA:
## -1.63592 ( -12.46785 to 9.196011 )
## LLoA:
## -35.16408 ( -45.99601 to -24.33215 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 81.5
## Minimum value for average measures: 49
## Maximum value for difference in measures: -3
## Minimum value for difference in measures: -21
##
## Bias: -10.7
## Standard deviation of bias: 5.9264
##
## Standard error of bias: 1.874092
## Standard error for limits of agreement: 3.317802
##
## Bias: -10.7
## Bias- upper 95% CI: -6.460509
## Bias- lower 95% CI: -14.93949
##
## Upper limit of agreement: 0.9157449
## Upper LOA- upper 95% CI: 8.421134
## Upper LOA- lower 95% CI: -6.589644
##
## Lower limit of agreement: -22.31574
## Lower LOA- upper 95% CI: -14.81036
## Lower LOA- lower 95% CI: -29.82113
##
## Derived measures:
## Mean of differences/means: -16.93737
## Point estimate of bias as proportion of lowest average: -21.83673
## Point estimate of bias as proportion of highest average -13.12883
## Spread of data between lower and upper LoAs: 23.23149
## Bias as proportion of LoA spread: -46.05817
##
## Bias:
## -10.7 ( -14.93949 to -6.460509 )
## ULoA:
## 0.9157449 ( -6.589644 to 8.421134 )
## LLoA:
## -22.31574 ( -29.82113 to -14.81036 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 209
## Minimum value for average measures: 88.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -63
##
## Bias: -20.7
## Standard deviation of bias: 16.04196
##
## Standard error of bias: 5.072913
## Standard error for limits of agreement: 8.980838
##
## Bias: -20.7
## Bias- upper 95% CI: -9.224274
## Bias- lower 95% CI: -32.17573
##
## Upper limit of agreement: 10.74224
## Upper LOA- upper 95% CI: 31.05831
## Upper LOA- lower 95% CI: -9.573827
##
## Lower limit of agreement: -52.14224
## Lower LOA- upper 95% CI: -31.82617
## Lower LOA- lower 95% CI: -72.45831
##
## Derived measures:
## Mean of differences/means: -14.53833
## Point estimate of bias as proportion of lowest average: -23.38983
## Point estimate of bias as proportion of highest average -9.904306
## Spread of data between lower and upper LoAs: 62.88448
## Bias as proportion of LoA spread: -32.9175
##
## Bias:
## -20.7 ( -32.17573 to -9.224274 )
## ULoA:
## 10.74224 ( -9.573827 to 31.05831 )
## LLoA:
## -52.14224 ( -72.45831 to -31.82617 )
4) Analyst 2 compared to Biospot:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 7
## Minimum value for average measures: 1
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: 0
##
## Bias: 0.1
## Standard deviation of bias: 0.3162278
##
## Standard error of bias: 0.1
## Standard error for limits of agreement: 0.1770351
##
## Bias: 0.1
## Bias- upper 95% CI: 0.3262157
## Bias- lower 95% CI: -0.1262157
##
## Upper limit of agreement: 0.7198064
## Upper LOA- upper 95% CI: 1.120288
## Upper LOA- lower 95% CI: 0.3193251
##
## Lower limit of agreement: -0.5198064
## Lower LOA- upper 95% CI: -0.1193251
## Lower LOA- lower 95% CI: -0.9202877
##
## Derived measures:
## Mean of differences/means: 4
## Point estimate of bias as proportion of lowest average: 10
## Point estimate of bias as proportion of highest average 1.428571
## Spread of data between lower and upper LoAs: 1.239613
## Bias as proportion of LoA spread: 8.067035
##
## Bias:
## 0.1 ( -0.1262157 to 0.3262157 )
## ULoA:
## 0.7198064 ( 0.3193251 to 1.120288 )
## LLoA:
## -0.5198064 ( -0.9202877 to -0.1193251 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 27
## Minimum value for average measures: 10.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -3
##
## Bias: -1.5
## Standard deviation of bias: 0.7071068
##
## Standard error of bias: 0.2236068
## Standard error for limits of agreement: 0.3958626
##
## Bias: -1.5
## Bias- upper 95% CI: -0.9941663
## Bias- lower 95% CI: -2.005834
##
## Upper limit of agreement: -0.1140707
## Upper LOA- upper 95% CI: 0.7814327
## Upper LOA- lower 95% CI: -1.009574
##
## Lower limit of agreement: -2.885929
## Lower LOA- upper 95% CI: -1.990426
## Lower LOA- lower 95% CI: -3.781433
##
## Derived measures:
## Mean of differences/means: -8.106903
## Point estimate of bias as proportion of lowest average: -14.28571
## Point estimate of bias as proportion of highest average -5.555556
## Spread of data between lower and upper LoAs: 2.771859
## Bias as proportion of LoA spread: -54.11531
##
## Bias:
## -1.5 ( -2.005834 to -0.9941663 )
## ULoA:
## -0.1140707 ( -1.009574 to 0.7814327 )
## LLoA:
## -2.885929 ( -3.781433 to -1.990426 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 79.5
## Minimum value for average measures: 42
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -6
##
## Bias: -2.3
## Standard deviation of bias: 2.58414
##
## Standard error of bias: 0.8171767
## Standard error for limits of agreement: 1.44669
##
## Bias: -2.3
## Bias- upper 95% CI: -0.4514178
## Bias- lower 95% CI: -4.148582
##
## Upper limit of agreement: 2.764914
## Upper LOA- upper 95% CI: 6.037554
## Upper LOA- lower 95% CI: -0.5077261
##
## Lower limit of agreement: -7.364914
## Lower LOA- upper 95% CI: -4.092274
## Lower LOA- lower 95% CI: -10.63755
##
## Derived measures:
## Mean of differences/means: -3.19665
## Point estimate of bias as proportion of lowest average: -5.47619
## Point estimate of bias as proportion of highest average -2.893082
## Spread of data between lower and upper LoAs: 10.12983
## Bias as proportion of LoA spread: -22.70522
##
## Bias:
## -2.3 ( -4.148582 to -0.4514178 )
## ULoA:
## 2.764914 ( -0.5077261 to 6.037554 )
## LLoA:
## -7.364914 ( -10.63755 to -4.092274 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 198
## Minimum value for average measures: 88
## Maximum value for difference in measures: 4
## Minimum value for difference in measures: -78
##
## Bias: -27.5
## Standard deviation of bias: 28.43023
##
## Standard error of bias: 8.990427
## Standard error for limits of agreement: 15.91621
##
## Bias: -27.5
## Bias- upper 95% CI: -7.162241
## Bias- lower 95% CI: -47.83776
##
## Upper limit of agreement: 28.22324
## Upper LOA- upper 95% CI: 64.22822
## Upper LOA- lower 95% CI: -7.781734
##
## Lower limit of agreement: -83.22324
## Lower LOA- upper 95% CI: -47.21827
## Lower LOA- lower 95% CI: -119.2282
##
## Derived measures:
## Mean of differences/means: -19.43515
## Point estimate of bias as proportion of lowest average: -31.25
## Point estimate of bias as proportion of highest average -13.88889
## Spread of data between lower and upper LoAs: 111.4465
## Bias as proportion of LoA spread: -24.67552
##
## Bias:
## -27.5 ( -47.83776 to -7.162241 )
## ULoA:
## 28.22324 ( -7.781734 to 64.22822 )
## LLoA:
## -83.22324 ( -119.2282 to -47.21827 )
5) Analyst 2 compared to AutoCol
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -2
##
## Bias: -0.2
## Standard deviation of bias: 0.6324555
##
## Standard error of bias: 0.2
## Standard error for limits of agreement: 0.3540703
##
## Bias: -0.2
## Bias- upper 95% CI: 0.2524314
## Bias- lower 95% CI: -0.6524314
##
## Upper limit of agreement: 1.039613
## Upper LOA- upper 95% CI: 1.840575
## Upper LOA- lower 95% CI: 0.2386503
##
## Lower limit of agreement: -1.439613
## Lower LOA- upper 95% CI: -0.6386503
## Lower LOA- lower 95% CI: -2.240575
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: -Inf
## Point estimate of bias as proportion of highest average -6.666667
## Spread of data between lower and upper LoAs: 2.479226
## Bias as proportion of LoA spread: -8.067035
##
## Bias:
## -0.2 ( -0.6524314 to 0.2524314 )
## ULoA:
## 1.039613 ( 0.2386503 to 1.840575 )
## LLoA:
## -1.439613 ( -2.240575 to -0.6386503 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 6
## Minimum value for average measures: 1
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -1
##
## Bias: 0.3
## Standard deviation of bias: 0.8232726
##
## Standard error of bias: 0.2603417
## Standard error for limits of agreement: 0.4608962
##
## Bias: 0.3
## Bias- upper 95% CI: 0.8889337
## Bias- lower 95% CI: -0.2889337
##
## Upper limit of agreement: 1.913614
## Upper LOA- upper 95% CI: 2.956234
## Upper LOA- lower 95% CI: 0.8709947
##
## Lower limit of agreement: -1.313614
## Lower LOA- upper 95% CI: -0.2709947
## Lower LOA- lower 95% CI: -2.356234
##
## Derived measures:
## Mean of differences/means: 2.888889
## Point estimate of bias as proportion of lowest average: 30
## Point estimate of bias as proportion of highest average 5
## Spread of data between lower and upper LoAs: 3.227229
## Bias as proportion of LoA spread: 9.295902
##
## Bias:
## 0.3 ( -0.2889337 to 0.8889337 )
## ULoA:
## 1.913614 ( 0.8709947 to 2.956234 )
## LLoA:
## -1.313614 ( -2.356234 to -0.2709947 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 38.5
## Minimum value for average measures: 15.5
## Maximum value for difference in measures: -6
## Minimum value for difference in measures: -30
##
## Bias: -18.4
## Standard deviation of bias: 8.50098
##
## Standard error of bias: 2.688246
## Standard error for limits of agreement: 4.75914
##
## Bias: -18.4
## Bias- upper 95% CI: -12.31877
## Bias- lower 95% CI: -24.48123
##
## Upper limit of agreement: -1.738079
## Upper LOA- upper 95% CI: 9.027844
## Upper LOA- lower 95% CI: -12.504
##
## Lower limit of agreement: -35.06192
## Lower LOA- upper 95% CI: -24.296
## Lower LOA- lower 95% CI: -45.82784
##
## Derived measures:
## Mean of differences/means: -65.79884
## Point estimate of bias as proportion of lowest average: -118.7097
## Point estimate of bias as proportion of highest average -47.79221
## Spread of data between lower and upper LoAs: 33.32384
## Bias as proportion of LoA spread: -55.21572
##
## Bias:
## -18.4 ( -24.48123 to -12.31877 )
## ULoA:
## -1.738079 ( -12.504 to 9.027844 )
## LLoA:
## -35.06192 ( -45.82784 to -24.296 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 81.5
## Minimum value for average measures: 49
## Maximum value for difference in measures: -3
## Minimum value for difference in measures: -21
##
## Bias: -10.7
## Standard deviation of bias: 5.9264
##
## Standard error of bias: 1.874092
## Standard error for limits of agreement: 3.317802
##
## Bias: -10.7
## Bias- upper 95% CI: -6.460509
## Bias- lower 95% CI: -14.93949
##
## Upper limit of agreement: 0.9157449
## Upper LOA- upper 95% CI: 8.421134
## Upper LOA- lower 95% CI: -6.589644
##
## Lower limit of agreement: -22.31574
## Lower LOA- upper 95% CI: -14.81036
## Lower LOA- lower 95% CI: -29.82113
##
## Derived measures:
## Mean of differences/means: -16.93737
## Point estimate of bias as proportion of lowest average: -21.83673
## Point estimate of bias as proportion of highest average -13.12883
## Spread of data between lower and upper LoAs: 23.23149
## Bias as proportion of LoA spread: -46.05817
##
## Bias:
## -10.7 ( -14.93949 to -6.460509 )
## ULoA:
## 0.9157449 ( -6.589644 to 8.421134 )
## LLoA:
## -22.31574 ( -29.82113 to -14.81036 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 193.5
## Minimum value for average measures: 89.5
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -57
##
## Bias: -29.2
## Standard deviation of bias: 19.52093
##
## Standard error of bias: 6.17306
## Standard error for limits of agreement: 10.92848
##
## Bias: -29.2
## Bias- upper 95% CI: -15.23557
## Bias- lower 95% CI: -43.16443
##
## Upper limit of agreement: 9.061021
## Upper LOA- upper 95% CI: 33.78297
## Upper LOA- lower 95% CI: -15.66093
##
## Lower limit of agreement: -67.46102
## Lower LOA- upper 95% CI: -42.73907
## Lower LOA- lower 95% CI: -92.18297
##
## Derived measures:
## Mean of differences/means: -21.0208
## Point estimate of bias as proportion of lowest average: -32.6257
## Point estimate of bias as proportion of highest average -15.09044
## Spread of data between lower and upper LoAs: 76.52204
## Bias as proportion of LoA spread: -38.15894
##
## Bias:
## -29.2 ( -43.16443 to -15.23557 )
## ULoA:
## 9.061021 ( -15.66093 to 33.78297 )
## LLoA:
## -67.46102 ( -92.18297 to -42.73907 )
6) Biospot compared to AutoCol :
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -2
##
## Bias: -0.2
## Standard deviation of bias: 0.6324555
##
## Standard error of bias: 0.2
## Standard error for limits of agreement: 0.3540703
##
## Bias: -0.2
## Bias- upper 95% CI: 0.2524314
## Bias- lower 95% CI: -0.6524314
##
## Upper limit of agreement: 1.039613
## Upper LOA- upper 95% CI: 1.840575
## Upper LOA- lower 95% CI: 0.2386503
##
## Lower limit of agreement: -1.439613
## Lower LOA- upper 95% CI: -0.6386503
## Lower LOA- lower 95% CI: -2.240575
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: -Inf
## Point estimate of bias as proportion of highest average -6.666667
## Spread of data between lower and upper LoAs: 2.479226
## Bias as proportion of LoA spread: -8.067035
##
## Bias:
## -0.2 ( -0.6524314 to 0.2524314 )
## ULoA:
## 1.039613 ( 0.2386503 to 1.840575 )
## LLoA:
## -1.439613 ( -2.240575 to -0.6386503 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 6
## Minimum value for average measures: 1
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -1
##
## Bias: 0.2
## Standard deviation of bias: 0.7888106
##
## Standard error of bias: 0.2494438
## Standard error for limits of agreement: 0.4416032
##
## Bias: 0.2
## Bias- upper 95% CI: 0.7642811
## Bias- lower 95% CI: -0.3642811
##
## Upper limit of agreement: 1.746069
## Upper LOA- upper 95% CI: 2.745045
## Upper LOA- lower 95% CI: 0.747093
##
## Lower limit of agreement: -1.346069
## Lower LOA- upper 95% CI: -0.347093
## Lower LOA- lower 95% CI: -2.345045
##
## Derived measures:
## Mean of differences/means: -1.111111
## Point estimate of bias as proportion of lowest average: 20
## Point estimate of bias as proportion of highest average 3.333333
## Spread of data between lower and upper LoAs: 3.092138
## Bias as proportion of LoA spread: 6.468017
##
## Bias:
## 0.2 ( -0.3642811 to 0.7642811 )
## ULoA:
## 1.746069 ( 0.747093 to 2.745045 )
## LLoA:
## -1.346069 ( -2.345045 to -0.347093 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 39
## Minimum value for average measures: 16
## Maximum value for difference in measures: -5
## Minimum value for difference in measures: -28
##
## Bias: -16.9
## Standard deviation of bias: 8.116513
##
## Standard error of bias: 2.566667
## Standard error for limits of agreement: 4.543902
##
## Bias: -16.9
## Bias- upper 95% CI: -11.0938
## Bias- lower 95% CI: -22.7062
##
## Upper limit of agreement: -0.9916352
## Upper LOA- upper 95% CI: 9.287385
## Upper LOA- lower 95% CI: -11.27065
##
## Lower limit of agreement: -32.80836
## Lower LOA- upper 95% CI: -22.52935
## Lower LOA- lower 95% CI: -43.08738
##
## Derived measures:
## Mean of differences/means: -58.59736
## Point estimate of bias as proportion of lowest average: -105.625
## Point estimate of bias as proportion of highest average -43.33333
## Spread of data between lower and upper LoAs: 31.81673
## Bias as proportion of LoA spread: -53.11671
##
## Bias:
## -16.9 ( -22.7062 to -11.0938 )
## ULoA:
## -0.9916352 ( -11.27065 to 9.287385 )
## LLoA:
## -32.80836 ( -43.08738 to -22.52935 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 82.5
## Minimum value for average measures: 50
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -20
##
## Bias: -8.4
## Standard deviation of bias: 6.995236
##
## Standard error of bias: 2.212088
## Standard error for limits of agreement: 3.916173
##
## Bias: -8.4
## Bias- upper 95% CI: -3.395909
## Bias- lower 95% CI: -13.40409
##
## Upper limit of agreement: 5.310663
## Upper LOA- upper 95% CI: 14.16966
## Upper LOA- lower 95% CI: -3.548335
##
## Lower limit of agreement: -22.11066
## Lower LOA- upper 95% CI: -13.25166
## Lower LOA- lower 95% CI: -30.96966
##
## Derived measures:
## Mean of differences/means: -13.75462
## Point estimate of bias as proportion of lowest average: -16.8
## Point estimate of bias as proportion of highest average -10.18182
## Spread of data between lower and upper LoAs: 27.42133
## Bias as proportion of LoA spread: -30.63309
##
## Bias:
## -8.4 ( -13.40409 to -3.395909 )
## ULoA:
## 5.310663 ( -3.548335 to 14.16966 )
## LLoA:
## -22.11066 ( -30.96966 to -13.25166 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 224.5
## Minimum value for average measures: 87.5
## Maximum value for difference in measures: 31
## Minimum value for difference in measures: -26
##
## Bias: -1.7
## Standard deviation of bias: 14.90749
##
## Standard error of bias: 4.714163
## Standard error for limits of agreement: 8.345725
##
## Bias: -1.7
## Bias- upper 95% CI: 8.964178
## Bias- lower 95% CI: -12.36418
##
## Upper limit of agreement: 27.51869
## Upper LOA- upper 95% CI: 46.39803
## Upper LOA- lower 95% CI: 8.639344
##
## Lower limit of agreement: -30.91869
## Lower LOA- upper 95% CI: -12.03934
## Lower LOA- lower 95% CI: -49.79803
##
## Derived measures:
## Mean of differences/means: -1.434511
## Point estimate of bias as proportion of lowest average: -1.942857
## Point estimate of bias as proportion of highest average -0.7572383
## Spread of data between lower and upper LoAs: 58.43737
## Bias as proportion of LoA spread: -2.909097
##
## Bias:
## -1.7 ( -12.36418 to 8.964178 )
## ULoA:
## 27.51869 ( 8.639344 to 46.39803 )
## LLoA:
## -30.91869 ( -49.79803 to -12.03934 )
2.3 Aspergillus brasiliensis Settle plates
1) Analyst 1 compared to Analyst 2:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 0
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average NaN
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 1
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3.5
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -1
##
## Bias: -0.1
## Standard deviation of bias: 0.3162278
##
## Standard error of bias: 0.1
## Standard error for limits of agreement: 0.1770351
##
## Bias: -0.1
## Bias- upper 95% CI: 0.1262157
## Bias- lower 95% CI: -0.3262157
##
## Upper limit of agreement: 0.5198064
## Upper LOA- upper 95% CI: 0.9202877
## Upper LOA- lower 95% CI: 0.1193251
##
## Lower limit of agreement: -0.7198064
## Lower LOA- upper 95% CI: -0.3193251
## Lower LOA- lower 95% CI: -1.120288
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: -Inf
## Point estimate of bias as proportion of highest average -2.857143
## Spread of data between lower and upper LoAs: 1.239613
## Bias as proportion of LoA spread: -8.067035
##
## Bias:
## -0.1 ( -0.3262157 to 0.1262157 )
## ULoA:
## 0.5198064 ( 0.1193251 to 0.9202877 )
## LLoA:
## -0.7198064 ( -1.120288 to -0.3193251 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 10.5
## Minimum value for average measures: 2
## Maximum value for difference in measures: 21
## Minimum value for difference in measures: 4
##
## Bias: 11.4
## Standard deviation of bias: 6.484169
##
## Standard error of bias: 2.050474
## Standard error for limits of agreement: 3.63006
##
## Bias: 11.4
## Bias- upper 95% CI: 16.03849
## Bias- lower 95% CI: 6.761505
##
## Upper limit of agreement: 24.10897
## Upper LOA- upper 95% CI: 32.32074
## Upper LOA- lower 95% CI: 15.89721
##
## Lower limit of agreement: -1.308971
## Lower LOA- upper 95% CI: 6.902795
## Lower LOA- lower 95% CI: -9.520736
##
## Derived measures:
## Mean of differences/means: 200
## Point estimate of bias as proportion of lowest average: 570
## Point estimate of bias as proportion of highest average 108.5714
## Spread of data between lower and upper LoAs: 25.41794
## Bias as proportion of LoA spread: 44.85021
##
## Bias:
## 11.4 ( 6.761505 to 16.03849 )
## ULoA:
## 24.10897 ( 15.89721 to 32.32074 )
## LLoA:
## -1.308971 ( -9.520736 to 6.902795 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 10
## Minimum value for average measures: 4
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -4
##
## Bias: -1.4
## Standard deviation of bias: 1.429841
##
## Standard error of bias: 0.4521553
## Standard error for limits of agreement: 0.8004738
##
## Bias: -1.4
## Bias- upper 95% CI: -0.3771536
## Bias- lower 95% CI: -2.422846
##
## Upper limit of agreement: 1.402488
## Upper LOA- upper 95% CI: 3.213285
## Upper LOA- lower 95% CI: -0.4083097
##
## Lower limit of agreement: -4.202488
## Lower LOA- upper 95% CI: -2.39169
## Lower LOA- lower 95% CI: -6.013285
##
## Derived measures:
## Mean of differences/means: -19.80427
## Point estimate of bias as proportion of lowest average: -35
## Point estimate of bias as proportion of highest average -14
## Spread of data between lower and upper LoAs: 5.604976
## Bias as proportion of LoA spread: -24.97781
##
## Bias:
## -1.4 ( -2.422846 to -0.3771536 )
## ULoA:
## 1.402488 ( -0.4083097 to 3.213285 )
## LLoA:
## -4.202488 ( -6.013285 to -2.39169 )
2) Analyst 1 compared to Biospot:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 0
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average NaN
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 0.5
## Minimum value for average measures: 0
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: 0
##
## Bias: 0.1
## Standard deviation of bias: 0.3162278
##
## Standard error of bias: 0.1
## Standard error for limits of agreement: 0.1770351
##
## Bias: 0.1
## Bias- upper 95% CI: 0.3262157
## Bias- lower 95% CI: -0.1262157
##
## Upper limit of agreement: 0.7198064
## Upper LOA- upper 95% CI: 1.120288
## Upper LOA- lower 95% CI: 0.3193251
##
## Lower limit of agreement: -0.5198064
## Lower LOA- upper 95% CI: -0.1193251
## Lower LOA- lower 95% CI: -0.9202877
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: Inf
## Point estimate of bias as proportion of highest average 20
## Spread of data between lower and upper LoAs: 1.239613
## Bias as proportion of LoA spread: 8.067035
##
## Bias:
## 0.1 ( -0.1262157 to 0.3262157 )
## ULoA:
## 0.7198064 ( 0.3193251 to 1.120288 )
## LLoA:
## -0.5198064 ( -0.9202877 to -0.1193251 )
50 cfu
## Number of comparisons: 7
## Maximum value for average measures: 15.5
## Minimum value for average measures: 0
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -29
##
## Bias: -3.857143
## Standard deviation of bias: 11.12697
##
## Standard error of bias: 4.2056
## Standard error for limits of agreement: 7.571075
##
## Bias: -3.857143
## Bias- upper 95% CI: 6.433591
## Bias- lower 95% CI: -14.14788
##
## Upper limit of agreement: 17.95172
## Upper LOA- upper 95% CI: 36.47748
## Upper LOA- lower 95% CI: -0.5740288
##
## Lower limit of agreement: -25.66601
## Lower LOA- upper 95% CI: -7.140257
## Lower LOA- lower 95% CI: -44.19176
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: -Inf
## Point estimate of bias as proportion of highest average -24.88479
## Spread of data between lower and upper LoAs: 43.61773
## Bias as proportion of LoA spread: -8.843061
##
## Bias:
## -3.857143 ( -14.14788 to 6.433591 )
## ULoA:
## 17.95172 ( -0.5740288 to 36.47748 )
## LLoA:
## -25.66601 ( -44.19176 to -7.140257 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 10.5
## Minimum value for average measures: 2
## Maximum value for difference in measures: 21
## Minimum value for difference in measures: 4
##
## Bias: 11.4
## Standard deviation of bias: 6.484169
##
## Standard error of bias: 2.050474
## Standard error for limits of agreement: 3.63006
##
## Bias: 11.4
## Bias- upper 95% CI: 16.03849
## Bias- lower 95% CI: 6.761505
##
## Upper limit of agreement: 24.10897
## Upper LOA- upper 95% CI: 32.32074
## Upper LOA- lower 95% CI: 15.89721
##
## Lower limit of agreement: -1.308971
## Lower LOA- upper 95% CI: 6.902795
## Lower LOA- lower 95% CI: -9.520736
##
## Derived measures:
## Mean of differences/means: 200
## Point estimate of bias as proportion of lowest average: 570
## Point estimate of bias as proportion of highest average 108.5714
## Spread of data between lower and upper LoAs: 25.41794
## Bias as proportion of LoA spread: 44.85021
##
## Bias:
## 11.4 ( 6.761505 to 16.03849 )
## ULoA:
## 24.10897 ( 15.89721 to 32.32074 )
## LLoA:
## -1.308971 ( -9.520736 to 6.902795 )
300 cfu
Biospot failed TNTC
3) Analyst 1 compared to AutoCol:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -6
##
## Bias: -2.5
## Standard deviation of bias: 1.581139
##
## Standard error of bias: 0.5
## Standard error for limits of agreement: 0.8851757
##
## Bias: -2.5
## Bias- upper 95% CI: -1.368921
## Bias- lower 95% CI: -3.631079
##
## Upper limit of agreement: 0.5990321
## Upper LOA- upper 95% CI: 2.601439
## Upper LOA- lower 95% CI: -1.403374
##
## Lower limit of agreement: -5.599032
## Lower LOA- upper 95% CI: -3.596626
## Lower LOA- lower 95% CI: -7.601439
##
## Derived measures:
## Mean of differences/means: -200
## Point estimate of bias as proportion of lowest average: -500
## Point estimate of bias as proportion of highest average -83.33333
## Spread of data between lower and upper LoAs: 6.198064
## Bias as proportion of LoA spread: -40.33517
##
## Bias:
## -2.5 ( -3.631079 to -1.368921 )
## ULoA:
## 0.5990321 ( -1.403374 to 2.601439 )
## LLoA:
## -5.599032 ( -7.601439 to -3.596626 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 4
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -6
##
## Bias: -2.8
## Standard deviation of bias: 1.813529
##
## Standard error of bias: 0.5734884
## Standard error for limits of agreement: 1.015276
##
## Bias: -2.8
## Bias- upper 95% CI: -1.502679
## Bias- lower 95% CI: -4.097321
##
## Upper limit of agreement: 0.7545176
## Upper LOA- upper 95% CI: 3.051231
## Upper LOA- lower 95% CI: -1.542196
##
## Lower limit of agreement: -6.354518
## Lower LOA- upper 95% CI: -4.057804
## Lower LOA- lower 95% CI: -8.651231
##
## Derived measures:
## Mean of differences/means: -195
## Point estimate of bias as proportion of lowest average: -560
## Point estimate of bias as proportion of highest average -70
## Spread of data between lower and upper LoAs: 7.109035
## Bias as proportion of LoA spread: -39.3865
##
## Bias:
## -2.8 ( -4.097321 to -1.502679 )
## ULoA:
## 0.7545176 ( -1.542196 to 3.051231 )
## LLoA:
## -6.354518 ( -8.651231 to -4.057804 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 1
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -4
##
## Bias: -1.2
## Standard deviation of bias: 1.75119
##
## Standard error of bias: 0.5537749
## Standard error for limits of agreement: 0.9803762
##
## Bias: -1.2
## Bias- upper 95% CI: 0.05272591
## Bias- lower 95% CI: -2.452726
##
## Upper limit of agreement: 2.232333
## Upper LOA- upper 95% CI: 4.450098
## Upper LOA- lower 95% CI: 0.01456757
##
## Lower limit of agreement: -4.632333
## Lower LOA- upper 95% CI: -2.414568
## Lower LOA- lower 95% CI: -6.850098
##
## Derived measures:
## Mean of differences/means: -90
## Point estimate of bias as proportion of lowest average: -120
## Point estimate of bias as proportion of highest average -40
## Spread of data between lower and upper LoAs: 6.864665
## Bias as proportion of LoA spread: -17.48082
##
## Bias:
## -1.2 ( -2.452726 to 0.05272591 )
## ULoA:
## 2.232333 ( 0.01456757 to 4.450098 )
## LLoA:
## -4.632333 ( -6.850098 to -2.414568 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 12
## Minimum value for average measures: 3
## Maximum value for difference in measures: 19
## Minimum value for difference in measures: 2
##
## Bias: 9.2
## Standard deviation of bias: 6.338594
##
## Standard error of bias: 2.00444
## Standard error for limits of agreement: 3.548562
##
## Bias: 9.2
## Bias- upper 95% CI: 13.73436
## Bias- lower 95% CI: 4.665643
##
## Upper limit of agreement: 21.62364
## Upper LOA- upper 95% CI: 29.65105
## Upper LOA- lower 95% CI: 13.59624
##
## Lower limit of agreement: -3.223645
## Lower LOA- upper 95% CI: 4.80376
## Lower LOA- lower 95% CI: -11.25105
##
## Derived measures:
## Mean of differences/means: 121.5016
## Point estimate of bias as proportion of lowest average: 306.6667
## Point estimate of bias as proportion of highest average 76.66667
## Spread of data between lower and upper LoAs: 24.84729
## Bias as proportion of LoA spread: 37.02617
##
## Bias:
## 9.2 ( 4.665643 to 13.73436 )
## ULoA:
## 21.62364 ( 13.59624 to 29.65105 )
## LLoA:
## -3.223645 ( -11.25105 to 4.80376 )
300 cfu
## Number of comparisons: 10
## Maximum value for average measures: 15
## Minimum value for average measures: 4
## Maximum value for difference in measures: 6
## Minimum value for difference in measures: -14
##
## Bias: -4.9
## Standard deviation of bias: 6.226288
##
## Standard error of bias: 1.968925
## Standard error for limits of agreement: 3.485689
##
## Bias: -4.9
## Bias- upper 95% CI: -0.4459816
## Bias- lower 95% CI: -9.354018
##
## Upper limit of agreement: 7.303525
## Upper LOA- upper 95% CI: 15.1887
## Upper LOA- lower 95% CI: -0.5816521
##
## Lower limit of agreement: -17.10353
## Lower LOA- upper 95% CI: -9.218348
## Lower LOA- lower 95% CI: -24.9887
##
## Derived measures:
## Mean of differences/means: -42.61901
## Point estimate of bias as proportion of lowest average: -122.5
## Point estimate of bias as proportion of highest average -32.66667
## Spread of data between lower and upper LoAs: 24.40705
## Bias as proportion of LoA spread: -20.07617
##
## Bias:
## -4.9 ( -9.354018 to -0.4459816 )
## ULoA:
## 7.303525 ( -0.5816521 to 15.1887 )
## LLoA:
## -17.10353 ( -24.9887 to -9.218348 )
4) Analyst 2 compared to Biospot:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 0
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average NaN
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 0.5
## Minimum value for average measures: 0
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: 0
##
## Bias: 0.1
## Standard deviation of bias: 0.3162278
##
## Standard error of bias: 0.1
## Standard error for limits of agreement: 0.1770351
##
## Bias: 0.1
## Bias- upper 95% CI: 0.3262157
## Bias- lower 95% CI: -0.1262157
##
## Upper limit of agreement: 0.7198064
## Upper LOA- upper 95% CI: 1.120288
## Upper LOA- lower 95% CI: 0.3193251
##
## Lower limit of agreement: -0.5198064
## Lower LOA- upper 95% CI: -0.1193251
## Lower LOA- lower 95% CI: -0.9202877
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: Inf
## Point estimate of bias as proportion of highest average 20
## Spread of data between lower and upper LoAs: 1.239613
## Bias as proportion of LoA spread: 8.067035
##
## Bias:
## 0.1 ( -0.1262157 to 0.3262157 )
## ULoA:
## 0.7198064 ( 0.3193251 to 1.120288 )
## LLoA:
## -0.5198064 ( -0.9202877 to -0.1193251 )
50 cfu
## Number of comparisons: 7
## Maximum value for average measures: 15.5
## Minimum value for average measures: 0
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -29
##
## Bias: -3.857143
## Standard deviation of bias: 11.12697
##
## Standard error of bias: 4.2056
## Standard error for limits of agreement: 7.571075
##
## Bias: -3.857143
## Bias- upper 95% CI: 6.433591
## Bias- lower 95% CI: -14.14788
##
## Upper limit of agreement: 17.95172
## Upper LOA- upper 95% CI: 36.47748
## Upper LOA- lower 95% CI: -0.5740288
##
## Lower limit of agreement: -25.66601
## Lower LOA- upper 95% CI: -7.140257
## Lower LOA- lower 95% CI: -44.19176
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: -Inf
## Point estimate of bias as proportion of highest average -24.88479
## Spread of data between lower and upper LoAs: 43.61773
## Bias as proportion of LoA spread: -8.843061
##
## Bias:
## -3.857143 ( -14.14788 to 6.433591 )
## ULoA:
## 17.95172 ( -0.5740288 to 36.47748 )
## LLoA:
## -25.66601 ( -44.19176 to -7.140257 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 0
## Minimum value for average measures: 0
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: 0
##
## Bias: 0
## Standard deviation of bias: 0
##
## Standard error of bias: 0
## Standard error for limits of agreement: 0
##
## Bias: 0
## Bias- upper 95% CI: 0
## Bias- lower 95% CI: 0
##
## Upper limit of agreement: 0
## Upper LOA- upper 95% CI: 0
## Upper LOA- lower 95% CI: 0
##
## Lower limit of agreement: 0
## Lower LOA- upper 95% CI: 0
## Lower LOA- lower 95% CI: 0
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average NaN
## Spread of data between lower and upper LoAs: 0
## Bias as proportion of LoA spread: NaN
##
## Bias:
## 0 ( 0 to 0 )
## ULoA:
## 0 ( 0 to 0 )
## LLoA:
## 0 ( 0 to 0 )
300 cfu
Biospot results failed TNTC
5) Analyst 2 compared to AutoCol:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -6
##
## Bias: -2.5
## Standard deviation of bias: 1.581139
##
## Standard error of bias: 0.5
## Standard error for limits of agreement: 0.8851757
##
## Bias: -2.5
## Bias- upper 95% CI: -1.368921
## Bias- lower 95% CI: -3.631079
##
## Upper limit of agreement: 0.5990321
## Upper LOA- upper 95% CI: 2.601439
## Upper LOA- lower 95% CI: -1.403374
##
## Lower limit of agreement: -5.599032
## Lower LOA- upper 95% CI: -3.596626
## Lower LOA- lower 95% CI: -7.601439
##
## Derived measures:
## Mean of differences/means: -200
## Point estimate of bias as proportion of lowest average: -500
## Point estimate of bias as proportion of highest average -83.33333
## Spread of data between lower and upper LoAs: 6.198064
## Bias as proportion of LoA spread: -40.33517
##
## Bias:
## -2.5 ( -3.631079 to -1.368921 )
## ULoA:
## 0.5990321 ( -1.403374 to 2.601439 )
## LLoA:
## -5.599032 ( -7.601439 to -3.596626 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 4
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -6
##
## Bias: -2.8
## Standard deviation of bias: 1.813529
##
## Standard error of bias: 0.5734884
## Standard error for limits of agreement: 1.015276
##
## Bias: -2.8
## Bias- upper 95% CI: -1.502679
## Bias- lower 95% CI: -4.097321
##
## Upper limit of agreement: 0.7545176
## Upper LOA- upper 95% CI: 3.051231
## Upper LOA- lower 95% CI: -1.542196
##
## Lower limit of agreement: -6.354518
## Lower LOA- upper 95% CI: -4.057804
## Lower LOA- lower 95% CI: -8.651231
##
## Derived measures:
## Mean of differences/means: -195
## Point estimate of bias as proportion of lowest average: -560
## Point estimate of bias as proportion of highest average -70
## Spread of data between lower and upper LoAs: 7.109035
## Bias as proportion of LoA spread: -39.3865
##
## Bias:
## -2.8 ( -4.097321 to -1.502679 )
## ULoA:
## 0.7545176 ( -1.542196 to 3.051231 )
## LLoA:
## -6.354518 ( -8.651231 to -4.057804 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3.5
## Minimum value for average measures: 1
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -4
##
## Bias: -1.1
## Standard deviation of bias: 1.852926
##
## Standard error of bias: 0.5859465
## Standard error for limits of agreement: 1.037331
##
## Bias: -1.1
## Bias- upper 95% CI: 0.2255031
## Bias- lower 95% CI: -2.425503
##
## Upper limit of agreement: 2.531734
## Upper LOA- upper 95% CI: 4.87834
## Upper LOA- lower 95% CI: 0.185128
##
## Lower limit of agreement: -4.731734
## Lower LOA- upper 95% CI: -2.385128
## Lower LOA- lower 95% CI: -7.07834
##
## Derived measures:
## Mean of differences/means: -87.14286
## Point estimate of bias as proportion of lowest average: -110
## Point estimate of bias as proportion of highest average -31.42857
## Spread of data between lower and upper LoAs: 7.263468
## Bias as proportion of LoA spread: -15.14428
##
## Bias:
## -1.1 ( -2.425503 to 0.2255031 )
## ULoA:
## 2.531734 ( 0.185128 to 4.87834 )
## LLoA:
## -4.731734 ( -7.07834 to -2.385128 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 1.5
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -3
##
## Bias: -2.2
## Standard deviation of bias: 0.6324555
##
## Standard error of bias: 0.2
## Standard error for limits of agreement: 0.3540703
##
## Bias: -2.2
## Bias- upper 95% CI: -1.747569
## Bias- lower 95% CI: -2.652431
##
## Upper limit of agreement: -0.9603872
## Upper LOA- upper 95% CI: -0.1594246
## Upper LOA- lower 95% CI: -1.76135
##
## Lower limit of agreement: -3.439613
## Lower LOA- upper 95% CI: -2.63865
## Lower LOA- lower 95% CI: -4.240575
##
## Derived measures:
## Mean of differences/means: -200
## Point estimate of bias as proportion of lowest average: -440
## Point estimate of bias as proportion of highest average -146.6667
## Spread of data between lower and upper LoAs: 2.479226
## Bias as proportion of LoA spread: -88.73738
##
## Bias:
## -2.2 ( -2.652431 to -1.747569 )
## ULoA:
## -0.9603872 ( -1.76135 to -0.1594246 )
## LLoA:
## -3.439613 ( -4.240575 to -2.63865 )
300 cfu
## Number of comparisons: 10
## Maximum value for average measures: 15.5
## Minimum value for average measures: 5
## Maximum value for difference in measures: 6
## Minimum value for difference in measures: -11
##
## Bias: -3.5
## Standard deviation of bias: 5.482295
##
## Standard error of bias: 1.733654
## Standard error for limits of agreement: 3.069176
##
## Bias: -3.5
## Bias- upper 95% CI: 0.4217974
## Bias- lower 95% CI: -7.421797
##
## Upper limit of agreement: 7.245298
## Upper LOA- upper 95% CI: 14.18826
## Upper LOA- lower 95% CI: 0.3023385
##
## Lower limit of agreement: -14.2453
## Lower LOA- upper 95% CI: -7.302338
## Lower LOA- lower 95% CI: -21.18826
##
## Derived measures:
## Mean of differences/means: -24.4063
## Point estimate of bias as proportion of lowest average: -70
## Point estimate of bias as proportion of highest average -22.58065
## Spread of data between lower and upper LoAs: 21.4906
## Bias as proportion of LoA spread: -16.28619
##
## Bias:
## -3.5 ( -7.421797 to 0.4217974 )
## ULoA:
## 7.245298 ( 0.3023385 to 14.18826 )
## LLoA:
## -14.2453 ( -21.18826 to -7.302338 )
6) Biospot compared to AutoCol:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -6
##
## Bias: -2.5
## Standard deviation of bias: 1.581139
##
## Standard error of bias: 0.5
## Standard error for limits of agreement: 0.8851757
##
## Bias: -2.5
## Bias- upper 95% CI: -1.368921
## Bias- lower 95% CI: -3.631079
##
## Upper limit of agreement: 0.5990321
## Upper LOA- upper 95% CI: 2.601439
## Upper LOA- lower 95% CI: -1.403374
##
## Lower limit of agreement: -5.599032
## Lower LOA- upper 95% CI: -3.596626
## Lower LOA- lower 95% CI: -7.601439
##
## Derived measures:
## Mean of differences/means: -200
## Point estimate of bias as proportion of lowest average: -500
## Point estimate of bias as proportion of highest average -83.33333
## Spread of data between lower and upper LoAs: 6.198064
## Bias as proportion of LoA spread: -40.33517
##
## Bias:
## -2.5 ( -3.631079 to -1.368921 )
## ULoA:
## 0.5990321 ( -1.403374 to 2.601439 )
## LLoA:
## -5.599032 ( -7.601439 to -3.596626 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 3.5
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -7
##
## Bias: -2.9
## Standard deviation of bias: 2.024846
##
## Standard error of bias: 0.6403124
## Standard error for limits of agreement: 1.133578
##
## Bias: -2.9
## Bias- upper 95% CI: -1.451513
## Bias- lower 95% CI: -4.348487
##
## Upper limit of agreement: 1.068698
## Upper LOA- upper 95% CI: 3.633029
## Upper LOA- lower 95% CI: -1.495634
##
## Lower limit of agreement: -6.868698
## Lower LOA- upper 95% CI: -4.304366
## Lower LOA- lower 95% CI: -9.433029
##
## Derived measures:
## Mean of differences/means: -200
## Point estimate of bias as proportion of lowest average: -580
## Point estimate of bias as proportion of highest average -82.85714
## Spread of data between lower and upper LoAs: 7.937395
## Bias as proportion of LoA spread: -36.53592
##
## Bias:
## -2.9 ( -4.348487 to -1.451513 )
## ULoA:
## 1.068698 ( -1.495634 to 3.633029 )
## LLoA:
## -6.868698 ( -9.433029 to -4.304366 )
50 cfu
## Number of comparisons: 7
## Maximum value for average measures: 16
## Minimum value for average measures: 1
## Maximum value for difference in measures: 28
## Minimum value for difference in measures: -5
##
## Bias: 1.857143
## Standard deviation of bias: 11.59639
##
## Standard error of bias: 4.383022
## Standard error for limits of agreement: 7.890476
##
## Bias: 1.857143
## Bias- upper 95% CI: 12.58201
## Bias- lower 95% CI: -8.867726
##
## Upper limit of agreement: 24.58606
## Upper LOA- upper 95% CI: 43.89336
## Upper LOA- lower 95% CI: 5.278762
##
## Lower limit of agreement: -20.87178
## Lower LOA- upper 95% CI: -1.564476
## Lower LOA- lower 95% CI: -40.17908
##
## Derived measures:
## Mean of differences/means: -127.381
## Point estimate of bias as proportion of lowest average: 185.7143
## Point estimate of bias as proportion of highest average 11.60714
## Spread of data between lower and upper LoAs: 45.45784
## Bias as proportion of LoA spread: 4.085418
##
## Bias:
## 1.857143 ( -8.867726 to 12.58201 )
## ULoA:
## 24.58606 ( 5.278762 to 43.89336 )
## LLoA:
## -20.87178 ( -40.17908 to -1.564476 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 1.5
## Minimum value for average measures: 0.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -3
##
## Bias: -2.2
## Standard deviation of bias: 0.6324555
##
## Standard error of bias: 0.2
## Standard error for limits of agreement: 0.3540703
##
## Bias: -2.2
## Bias- upper 95% CI: -1.747569
## Bias- lower 95% CI: -2.652431
##
## Upper limit of agreement: -0.9603872
## Upper LOA- upper 95% CI: -0.1594246
## Upper LOA- lower 95% CI: -1.76135
##
## Lower limit of agreement: -3.439613
## Lower LOA- upper 95% CI: -2.63865
## Lower LOA- lower 95% CI: -4.240575
##
## Derived measures:
## Mean of differences/means: -200
## Point estimate of bias as proportion of lowest average: -440
## Point estimate of bias as proportion of highest average -146.6667
## Spread of data between lower and upper LoAs: 2.479226
## Bias as proportion of LoA spread: -88.73738
##
## Bias:
## -2.2 ( -2.652431 to -1.747569 )
## ULoA:
## -0.9603872 ( -1.76135 to -0.1594246 )
## LLoA:
## -3.439613 ( -4.240575 to -2.63865 )
300 cfu
Biospot failed TNTC
2.4 Pseudomonas aeruginosa Settle plates
1) Analyst 1 compared to Analyst 2:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 2
## Minimum value for average measures: 0
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -1
##
## Bias: 0
## Standard deviation of bias: 0.4714045
##
## Standard error of bias: 0.1490712
## Standard error for limits of agreement: 0.2639084
##
## Bias: 0
## Bias- upper 95% CI: 0.3372225
## Bias- lower 95% CI: -0.3372225
##
## Upper limit of agreement: 0.9239529
## Upper LOA- upper 95% CI: 1.520955
## Upper LOA- lower 95% CI: 0.3269506
##
## Lower limit of agreement: -0.9239529
## Lower LOA- upper 95% CI: -0.3269506
## Lower LOA- lower 95% CI: -1.520955
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: NaN
## Point estimate of bias as proportion of highest average 0
## Spread of data between lower and upper LoAs: 1.847906
## Bias as proportion of LoA spread: 0
##
## Bias:
## 0 ( -0.3372225 to 0.3372225 )
## ULoA:
## 0.9239529 ( 0.3269506 to 1.520955 )
## LLoA:
## -0.9239529 ( -1.520955 to -0.3269506 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 11.5
## Minimum value for average measures: 2
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -3
##
## Bias: -0.6
## Standard deviation of bias: 1.074968
##
## Standard error of bias: 0.3399346
## Standard error for limits of agreement: 0.6018037
##
## Bias: -0.6
## Bias- upper 95% CI: 0.1689856
## Bias- lower 95% CI: -1.368986
##
## Upper limit of agreement: 1.506937
## Upper LOA- upper 95% CI: 2.868311
## Upper LOA- lower 95% CI: 0.1455621
##
## Lower limit of agreement: -2.706937
## Lower LOA- upper 95% CI: -1.345562
## Lower LOA- lower 95% CI: -4.068311
##
## Derived measures:
## Mean of differences/means: -5.661327
## Point estimate of bias as proportion of lowest average: -30
## Point estimate of bias as proportion of highest average -5.217391
## Spread of data between lower and upper LoAs: 4.213873
## Bias as proportion of LoA spread: -14.23868
##
## Bias:
## -0.6 ( -1.368986 to 0.1689856 )
## ULoA:
## 1.506937 ( 0.1455621 to 2.868311 )
## LLoA:
## -2.706937 ( -4.068311 to -1.345562 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 24
## Minimum value for average measures: 11
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -3
##
## Bias: -1.1
## Standard deviation of bias: 1.197219
##
## Standard error of bias: 0.3785939
## Standard error for limits of agreement: 0.6702442
##
## Bias: -1.1
## Bias- upper 95% CI: -0.2435611
## Bias- lower 95% CI: -1.956439
##
## Upper limit of agreement: 1.246549
## Upper LOA- upper 95% CI: 2.762747
## Upper LOA- lower 95% CI: -0.2696485
##
## Lower limit of agreement: -3.446549
## Lower LOA- upper 95% CI: -1.930352
## Lower LOA- lower 95% CI: -4.962747
##
## Derived measures:
## Mean of differences/means: -6.820803
## Point estimate of bias as proportion of lowest average: -10
## Point estimate of bias as proportion of highest average -4.583333
## Spread of data between lower and upper LoAs: 4.693098
## Bias as proportion of LoA spread: -23.43867
##
## Bias:
## -1.1 ( -1.956439 to -0.2435611 )
## ULoA:
## 1.246549 ( -0.2696485 to 2.762747 )
## LLoA:
## -3.446549 ( -4.962747 to -1.930352 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 37
## Minimum value for average measures: 25
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -3
##
## Bias: -0.6
## Standard deviation of bias: 1.173788
##
## Standard error of bias: 0.3711843
## Standard error for limits of agreement: 0.6571266
##
## Bias: -0.6
## Bias- upper 95% CI: 0.2396772
## Bias- lower 95% CI: -1.439677
##
## Upper limit of agreement: 1.700624
## Upper LOA- upper 95% CI: 3.187148
## Upper LOA- lower 95% CI: 0.2141004
##
## Lower limit of agreement: -2.900624
## Lower LOA- upper 95% CI: -1.4141
## Lower LOA- lower 95% CI: -4.387148
##
## Derived measures:
## Mean of differences/means: -2.008808
## Point estimate of bias as proportion of lowest average: -2.4
## Point estimate of bias as proportion of highest average -1.621622
## Spread of data between lower and upper LoAs: 4.601248
## Bias as proportion of LoA spread: -13.03994
##
## Bias:
## -0.6 ( -1.439677 to 0.2396772 )
## ULoA:
## 1.700624 ( 0.2141004 to 3.187148 )
## LLoA:
## -2.900624 ( -4.387148 to -1.4141 )
300 cfu
## Number of comparisons: 10
## Maximum value for average measures: 80
## Minimum value for average measures: 63
## Maximum value for difference in measures: -2
## Minimum value for difference in measures: -14
##
## Bias: -6.2
## Standard deviation of bias: 3.966527
##
## Standard error of bias: 1.254326
## Standard error for limits of agreement: 2.220597
##
## Bias: -6.2
## Bias- upper 95% CI: -3.362518
## Bias- lower 95% CI: -9.037482
##
## Upper limit of agreement: 1.574392
## Upper LOA- upper 95% CI: 6.597733
## Upper LOA- lower 95% CI: -3.448948
##
## Lower limit of agreement: -13.97439
## Lower LOA- upper 95% CI: -8.951052
## Lower LOA- lower 95% CI: -18.99773
##
## Derived measures:
## Mean of differences/means: -8.705613
## Point estimate of bias as proportion of lowest average: -9.84127
## Point estimate of bias as proportion of highest average -7.75
## Spread of data between lower and upper LoAs: 15.54878
## Bias as proportion of LoA spread: -39.8745
##
## Bias:
## -6.2 ( -9.037482 to -3.362518 )
## ULoA:
## 1.574392 ( -3.448948 to 6.597733 )
## LLoA:
## -13.97439 ( -18.99773 to -8.951052 )
2) Analyst 1 compared to Biospot:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 1.5
## Minimum value for average measures: 0
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -1
##
## Bias: 0.1
## Standard deviation of bias: 0.7378648
##
## Standard error of bias: 0.2333333
## Standard error for limits of agreement: 0.413082
##
## Bias: 0.1
## Bias- upper 95% CI: 0.6278367
## Bias- lower 95% CI: -0.4278367
##
## Upper limit of agreement: 1.546215
## Upper LOA- upper 95% CI: 2.480671
## Upper LOA- lower 95% CI: 0.6117586
##
## Lower limit of agreement: -1.346215
## Lower LOA- upper 95% CI: -0.4117586
## Lower LOA- lower 95% CI: -2.280671
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: Inf
## Point estimate of bias as proportion of highest average 6.666667
## Spread of data between lower and upper LoAs: 2.89243
## Bias as proportion of LoA spread: 3.457301
##
## Bias:
## 0.1 ( -0.4278367 to 0.6278367 )
## ULoA:
## 1.546215 ( 0.6117586 to 2.480671 )
## LLoA:
## -1.346215 ( -2.280671 to -0.4117586 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 56.5
## Minimum value for average measures: 1
## Maximum value for difference in measures: 3
## Minimum value for difference in measures: -95
##
## Bias: -40.4
## Standard deviation of bias: 36.98708
##
## Standard error of bias: 11.69634
## Standard error for limits of agreement: 20.70664
##
## Bias: -40.4
## Bias- upper 95% CI: -13.94103
## Bias- lower 95% CI: -66.85897
##
## Upper limit of agreement: 32.09469
## Upper LOA- upper 95% CI: 78.93635
## Upper LOA- lower 95% CI: -14.74698
##
## Lower limit of agreement: -112.8947
## Lower LOA- upper 95% CI: -66.05302
## Lower LOA- lower 95% CI: -159.7364
##
## Derived measures:
## Mean of differences/means: -74.95479
## Point estimate of bias as proportion of lowest average: -4040
## Point estimate of bias as proportion of highest average -71.50442
## Spread of data between lower and upper LoAs: 144.9894
## Bias as proportion of LoA spread: -27.86411
##
## Bias:
## -40.4 ( -66.85897 to -13.94103 )
## ULoA:
## 32.09469 ( -14.74698 to 78.93635 )
## LLoA:
## -112.8947 ( -159.7364 to -66.05302 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 92
## Minimum value for average measures: 22.5
## Maximum value for difference in measures: -7
## Minimum value for difference in measures: -148
##
## Bias: -75.2
## Standard deviation of bias: 40.92215
##
## Standard error of bias: 12.94072
## Standard error for limits of agreement: 22.90962
##
## Bias: -75.2
## Bias- upper 95% CI: -45.92606
## Bias- lower 95% CI: -104.4739
##
## Upper limit of agreement: 5.007411
## Upper LOA- upper 95% CI: 56.83257
## Upper LOA- lower 95% CI: -46.81775
##
## Lower limit of agreement: -155.4074
## Lower LOA- upper 95% CI: -103.5822
## Lower LOA- lower 95% CI: -207.2326
##
## Derived measures:
## Mean of differences/means: -126.1543
## Point estimate of bias as proportion of lowest average: -334.2222
## Point estimate of bias as proportion of highest average -81.73913
## Spread of data between lower and upper LoAs: 160.4148
## Bias as proportion of LoA spread: -46.87846
##
## Bias:
## -75.2 ( -104.4739 to -45.92606 )
## ULoA:
## 5.007411 ( -46.81775 to 56.83257 )
## LLoA:
## -155.4074 ( -207.2326 to -103.5822 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 80
## Minimum value for average measures: 52
## Maximum value for difference in measures: -52
## Minimum value for difference in measures: -108
##
## Bias: -79.8
## Standard deviation of bias: 17.27426
##
## Standard error of bias: 5.4626
## Standard error for limits of agreement: 9.670721
##
## Bias: -79.8
## Bias- upper 95% CI: -67.44274
## Bias- lower 95% CI: -92.15726
##
## Upper limit of agreement: -45.94245
## Upper LOA- upper 95% CI: -24.06576
## Upper LOA- lower 95% CI: -67.81915
##
## Lower limit of agreement: -113.6575
## Lower LOA- upper 95% CI: -91.78085
## Lower LOA- lower 95% CI: -135.5342
##
## Derived measures:
## Mean of differences/means: -114.5429
## Point estimate of bias as proportion of lowest average: -153.4615
## Point estimate of bias as proportion of highest average -99.75
## Spread of data between lower and upper LoAs: 67.71509
## Bias as proportion of LoA spread: -117.8467
##
## Bias:
## -79.8 ( -92.15726 to -67.44274 )
## ULoA:
## -45.94245 ( -67.81915 to -24.06576 )
## LLoA:
## -113.6575 ( -135.5342 to -91.78085 )
300 cfu
## Number of comparisons: 10
## Maximum value for average measures: 98
## Minimum value for average measures: 68
## Maximum value for difference in measures: -14
## Minimum value for difference in measures: -58
##
## Bias: -33.6
## Standard deviation of bias: 15.07168
##
## Standard error of bias: 4.766084
## Standard error for limits of agreement: 8.437643
##
## Bias: -33.6
## Bias- upper 95% CI: -22.81837
## Bias- lower 95% CI: -44.38163
##
## Upper limit of agreement: -4.059506
## Upper LOA- upper 95% CI: 15.02777
## Upper LOA- lower 95% CI: -23.14678
##
## Lower limit of agreement: -63.14049
## Lower LOA- upper 95% CI: -44.05322
## Lower LOA- lower 95% CI: -82.22777
##
## Derived measures:
## Mean of differences/means: -38.86337
## Point estimate of bias as proportion of lowest average: -49.41176
## Point estimate of bias as proportion of highest average -34.28571
## Spread of data between lower and upper LoAs: 59.08099
## Bias as proportion of LoA spread: -56.87109
##
## Bias:
## -33.6 ( -44.38163 to -22.81837 )
## ULoA:
## -4.059506 ( -23.14678 to 15.02777 )
## LLoA:
## -63.14049 ( -82.22777 to -44.05322 )
3) Analyst 1 compared to AutoCol:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 32.5
## Minimum value for average measures: 1.5
## Maximum value for difference in measures: -1
## Minimum value for difference in measures: -65
##
## Bias: -33.7
## Standard deviation of bias: 23.05573
##
## Standard error of bias: 7.290862
## Standard error for limits of agreement: 12.90739
##
## Bias: -33.7
## Bias- upper 95% CI: -17.20692
## Bias- lower 95% CI: -50.19308
##
## Upper limit of agreement: 11.48923
## Upper LOA- upper 95% CI: 40.68777
## Upper LOA- lower 95% CI: -17.70931
##
## Lower limit of agreement: -78.88923
## Lower LOA- upper 95% CI: -49.69069
## Lower LOA- lower 95% CI: -108.0878
##
## Derived measures:
## Mean of differences/means: -178.6667
## Point estimate of bias as proportion of lowest average: -2246.667
## Point estimate of bias as proportion of highest average -103.6923
## Spread of data between lower and upper LoAs: 90.37846
## Bias as proportion of LoA spread: -37.28765
##
## Bias:
## -33.7 ( -50.19308 to -17.20692 )
## ULoA:
## 11.48923 ( -17.70931 to 40.68777 )
## LLoA:
## -78.88923 ( -108.0878 to -49.69069 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 11
## Minimum value for average measures: 4
## Maximum value for difference in measures: 1
## Minimum value for difference in measures: -4
##
## Bias: -2.8
## Standard deviation of bias: 1.619328
##
## Standard error of bias: 0.5120764
## Standard error for limits of agreement: 0.9065551
##
## Bias: -2.8
## Bias- upper 95% CI: -1.641603
## Bias- lower 95% CI: -3.958397
##
## Upper limit of agreement: 0.3738823
## Upper LOA- upper 95% CI: 2.424652
## Upper LOA- lower 95% CI: -1.676888
##
## Lower limit of agreement: -5.973882
## Lower LOA- upper 95% CI: -3.923112
## Lower LOA- lower 95% CI: -8.024652
##
## Derived measures:
## Mean of differences/means: -42.16552
## Point estimate of bias as proportion of lowest average: -70
## Point estimate of bias as proportion of highest average -25.45455
## Spread of data between lower and upper LoAs: 6.347765
## Bias as proportion of LoA spread: -44.11002
##
## Bias:
## -2.8 ( -3.958397 to -1.641603 )
## ULoA:
## 0.3738823 ( -1.676888 to 2.424652 )
## LLoA:
## -5.973882 ( -8.024652 to -3.923112 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 21.5
## Minimum value for average measures: 9
## Maximum value for difference in measures: 6
## Minimum value for difference in measures: -2
##
## Bias: 1.8
## Standard deviation of bias: 2.485514
##
## Standard error of bias: 0.7859884
## Standard error for limits of agreement: 1.391476
##
## Bias: 1.8
## Bias- upper 95% CI: 3.578029
## Bias- lower 95% CI: 0.02197069
##
## Upper limit of agreement: 6.671607
## Upper LOA- upper 95% CI: 9.819343
## Upper LOA- lower 95% CI: 3.52387
##
## Lower limit of agreement: -3.071607
## Lower LOA- upper 95% CI: 0.0761299
## Lower LOA- lower 95% CI: -6.219343
##
## Derived measures:
## Mean of differences/means: 11.0902
## Point estimate of bias as proportion of lowest average: 20
## Point estimate of bias as proportion of highest average 8.372093
## Spread of data between lower and upper LoAs: 9.743213
## Bias as proportion of LoA spread: 18.4744
##
## Bias:
## 1.8 ( 0.02197069 to 3.578029 )
## ULoA:
## 6.671607 ( 3.52387 to 9.819343 )
## LLoA:
## -3.071607 ( -6.219343 to 0.0761299 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 28.5
## Minimum value for average measures: 20.5
## Maximum value for difference in measures: 17
## Minimum value for difference in measures: 1
##
## Bias: 10.8
## Standard deviation of bias: 5.116422
##
## Standard error of bias: 1.617955
## Standard error for limits of agreement: 2.864348
##
## Bias: 10.8
## Bias- upper 95% CI: 14.46007
## Bias- lower 95% CI: 7.139932
##
## Upper limit of agreement: 20.82819
## Upper LOA- upper 95% CI: 27.30779
## Upper LOA- lower 95% CI: 14.34858
##
## Lower limit of agreement: 0.7718122
## Lower LOA- upper 95% CI: 7.251419
## Lower LOA- lower 95% CI: -5.707794
##
## Derived measures:
## Mean of differences/means: 45.51476
## Point estimate of bias as proportion of lowest average: 52.68293
## Point estimate of bias as proportion of highest average 37.89474
## Spread of data between lower and upper LoAs: 20.05638
## Bias as proportion of LoA spread: 53.84821
##
## Bias:
## 10.8 ( 7.139932 to 14.46007 )
## ULoA:
## 20.82819 ( 14.34858 to 27.30779 )
## LLoA:
## 0.7718122 ( -5.707794 to 7.251419 )
300 cfu
## Number of comparisons: 10
## Maximum value for average measures: 60.5
## Minimum value for average measures: 48.5
## Maximum value for difference in measures: 38
## Minimum value for difference in measures: 4
##
## Bias: 22
## Standard deviation of bias: 11.28421
##
## Standard error of bias: 3.56838
## Standard error for limits of agreement: 6.317286
##
## Bias: 22
## Bias- upper 95% CI: 30.07224
## Bias- lower 95% CI: 13.92776
##
## Upper limit of agreement: 44.11705
## Upper LOA- upper 95% CI: 58.40774
## Upper LOA- lower 95% CI: 29.82635
##
## Lower limit of agreement: -0.1170462
## Lower LOA- upper 95% CI: 14.17365
## Lower LOA- lower 95% CI: -14.40774
##
## Derived measures:
## Mean of differences/means: 40.63054
## Point estimate of bias as proportion of lowest average: 45.36082
## Point estimate of bias as proportion of highest average 36.36364
## Spread of data between lower and upper LoAs: 44.23409
## Bias as proportion of LoA spread: 49.73539
##
## Bias:
## 22 ( 13.92776 to 30.07224 )
## ULoA:
## 44.11705 ( 29.82635 to 58.40774 )
## LLoA:
## -0.1170462 ( -14.40774 to 14.17365 )
4) Analyst 2 compared to Biospot:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 1
## Minimum value for average measures: 0
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -2
##
## Bias: 0.1
## Standard deviation of bias: 0.9944289
##
## Standard error of bias: 0.314466
## Standard error for limits of agreement: 0.5567154
##
## Bias: 0.1
## Bias- upper 95% CI: 0.8113716
## Bias- lower 95% CI: -0.6113716
##
## Upper limit of agreement: 2.049081
## Upper LOA- upper 95% CI: 3.308458
## Upper LOA- lower 95% CI: 0.789703
##
## Lower limit of agreement: -1.849081
## Lower LOA- upper 95% CI: -0.589703
## Lower LOA- lower 95% CI: -3.108458
##
## Derived measures:
## Mean of differences/means: NaN
## Point estimate of bias as proportion of lowest average: Inf
## Point estimate of bias as proportion of highest average 10
## Spread of data between lower and upper LoAs: 3.898161
## Bias as proportion of LoA spread: 2.565312
##
## Bias:
## 0.1 ( -0.6113716 to 0.8113716 )
## ULoA:
## 2.049081 ( 0.789703 to 3.308458 )
## LLoA:
## -1.849081 ( -3.108458 to -0.589703 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 56.5
## Minimum value for average measures: 1
## Maximum value for difference in measures: 3
## Minimum value for difference in measures: -95
##
## Bias: -39.8
## Standard deviation of bias: 36.78405
##
## Standard error of bias: 11.63214
## Standard error for limits of agreement: 20.59297
##
## Bias: -39.8
## Bias- upper 95% CI: -13.48627
## Bias- lower 95% CI: -66.11373
##
## Upper limit of agreement: 32.29675
## Upper LOA- upper 95% CI: 78.88129
## Upper LOA- lower 95% CI: -14.2878
##
## Lower limit of agreement: -111.8967
## Lower LOA- upper 95% CI: -65.3122
## Lower LOA- lower 95% CI: -158.4813
##
## Derived measures:
## Mean of differences/means: -72.07381
## Point estimate of bias as proportion of lowest average: -3980
## Point estimate of bias as proportion of highest average -70.44248
## Spread of data between lower and upper LoAs: 144.1935
## Bias as proportion of LoA spread: -27.6018
##
## Bias:
## -39.8 ( -66.11373 to -13.48627 )
## ULoA:
## 32.29675 ( -14.2878 to 78.88129 )
## LLoA:
## -111.8967 ( -158.4813 to -65.3122 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 93
## Minimum value for average measures: 22
## Maximum value for difference in measures: -8
## Minimum value for difference in measures: -146
##
## Bias: -74.1
## Standard deviation of bias: 40.34421
##
## Standard error of bias: 12.75796
## Standard error for limits of agreement: 22.58607
##
## Bias: -74.1
## Bias- upper 95% CI: -45.23949
## Bias- lower 95% CI: -102.9605
##
## Upper limit of agreement: 4.974658
## Upper LOA- upper 95% CI: 56.0679
## Upper LOA- lower 95% CI: -46.11859
##
## Lower limit of agreement: -153.1747
## Lower LOA- upper 95% CI: -102.0814
## Lower LOA- lower 95% CI: -204.2679
##
## Derived measures:
## Mean of differences/means: -122.9275
## Point estimate of bias as proportion of lowest average: -336.8182
## Point estimate of bias as proportion of highest average -79.67742
## Spread of data between lower and upper LoAs: 158.1493
## Bias as proportion of LoA spread: -46.85445
##
## Bias:
## -74.1 ( -102.9605 to -45.23949 )
## ULoA:
## 4.974658 ( -46.11859 to 56.0679 )
## LLoA:
## -153.1747 ( -204.2679 to -102.0814 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 80.5
## Minimum value for average measures: 52
## Maximum value for difference in measures: -52
## Minimum value for difference in measures: -107
##
## Bias: -79.2
## Standard deviation of bias: 16.75178
##
## Standard error of bias: 5.297379
## Standard error for limits of agreement: 9.378222
##
## Bias: -79.2
## Bias- upper 95% CI: -67.2165
## Bias- lower 95% CI: -91.1835
##
## Upper limit of agreement: -46.36651
## Upper LOA- upper 95% CI: -25.15149
## Upper LOA- lower 95% CI: -67.58152
##
## Lower limit of agreement: -112.0335
## Lower LOA- upper 95% CI: -90.81848
## Lower LOA- lower 95% CI: -133.2485
##
## Derived measures:
## Mean of differences/means: -113.2918
## Point estimate of bias as proportion of lowest average: -152.3077
## Point estimate of bias as proportion of highest average -98.38509
## Spread of data between lower and upper LoAs: 65.66699
## Bias as proportion of LoA spread: -120.6085
##
## Bias:
## -79.2 ( -91.1835 to -67.2165 )
## ULoA:
## -46.36651 ( -67.58152 to -25.15149 )
## LLoA:
## -112.0335 ( -133.2485 to -90.81848 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 99.5
## Minimum value for average measures: 70
## Maximum value for difference in measures: -10
## Minimum value for difference in measures: -55
##
## Bias: -27.4
## Standard deviation of bias: 16.561
##
## Standard error of bias: 5.237048
## Standard error for limits of agreement: 9.271414
##
## Bias: -27.4
## Bias- upper 95% CI: -15.55298
## Bias- lower 95% CI: -39.24702
##
## Upper limit of agreement: 5.059557
## Upper LOA- upper 95% CI: 26.03295
## Upper LOA- lower 95% CI: -15.91384
##
## Lower limit of agreement: -59.85956
## Lower LOA- upper 95% CI: -38.88616
## Lower LOA- lower 95% CI: -80.83295
##
## Derived measures:
## Mean of differences/means: -30.39048
## Point estimate of bias as proportion of lowest average: -39.14286
## Point estimate of bias as proportion of highest average -27.53769
## Spread of data between lower and upper LoAs: 64.91911
## Bias as proportion of LoA spread: -42.20637
##
## Bias:
## -27.4 ( -39.24702 to -15.55298 )
## ULoA:
## 5.059557 ( -15.91384 to 26.03295 )
## LLoA:
## -59.85956 ( -80.83295 to -38.88616 )
5) Analyst 2 compared to AutoCol:
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 32.5
## Minimum value for average measures: 1
## Maximum value for difference in measures: -2
## Minimum value for difference in measures: -65
##
## Bias: -33.7
## Standard deviation of bias: 23.01232
##
## Standard error of bias: 7.277133
## Standard error for limits of agreement: 12.88308
##
## Bias: -33.7
## Bias- upper 95% CI: -17.23798
## Bias- lower 95% CI: -50.16202
##
## Upper limit of agreement: 11.40414
## Upper LOA- upper 95% CI: 40.5477
## Upper LOA- lower 95% CI: -17.73942
##
## Lower limit of agreement: -78.80414
## Lower LOA- upper 95% CI: -49.66058
## Lower LOA- lower 95% CI: -107.9477
##
## Derived measures:
## Mean of differences/means: -188.6667
## Point estimate of bias as proportion of lowest average: -3370
## Point estimate of bias as proportion of highest average -103.6923
## Spread of data between lower and upper LoAs: 90.20828
## Bias as proportion of LoA spread: -37.35799
##
## Bias:
## -33.7 ( -50.16202 to -17.23798 )
## ULoA:
## 11.40414 ( -17.73942 to 40.5477 )
## LLoA:
## -78.80414 ( -107.9477 to -49.66058 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 12.5
## Minimum value for average measures: 4
## Maximum value for difference in measures: 2
## Minimum value for difference in measures: -4
##
## Bias: -2.2
## Standard deviation of bias: 2.347576
##
## Standard error of bias: 0.7423686
## Standard error for limits of agreement: 1.314253
##
## Bias: -2.2
## Bias- upper 95% CI: -0.5206456
## Bias- lower 95% CI: -3.879354
##
## Upper limit of agreement: 2.401248
## Upper LOA- upper 95% CI: 5.374295
## Upper LOA- lower 95% CI: -0.5717991
##
## Lower limit of agreement: -6.801248
## Lower LOA- upper 95% CI: -3.828201
## Lower LOA- lower 95% CI: -9.774295
##
## Derived measures:
## Mean of differences/means: -36.50159
## Point estimate of bias as proportion of lowest average: -55
## Point estimate of bias as proportion of highest average -17.6
## Spread of data between lower and upper LoAs: 9.202496
## Bias as proportion of LoA spread: -23.90656
##
## Bias:
## -2.2 ( -3.879354 to -0.5206456 )
## ULoA:
## 2.401248 ( -0.5717991 to 5.374295 )
## LLoA:
## -6.801248 ( -9.774295 to -3.828201 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 21.5
## Minimum value for average measures: 10
## Maximum value for difference in measures: 6
## Minimum value for difference in measures: -1
##
## Bias: 2.9
## Standard deviation of bias: 2.024846
##
## Standard error of bias: 0.6403124
## Standard error for limits of agreement: 1.133578
##
## Bias: 2.9
## Bias- upper 95% CI: 4.348487
## Bias- lower 95% CI: 1.451513
##
## Upper limit of agreement: 6.868698
## Upper LOA- upper 95% CI: 9.433029
## Upper LOA- lower 95% CI: 4.304366
##
## Lower limit of agreement: -1.068698
## Lower LOA- upper 95% CI: 1.495634
## Lower LOA- lower 95% CI: -3.633029
##
## Derived measures:
## Mean of differences/means: 17.86127
## Point estimate of bias as proportion of lowest average: 29
## Point estimate of bias as proportion of highest average 13.48837
## Spread of data between lower and upper LoAs: 7.937395
## Bias as proportion of LoA spread: 36.53592
##
## Bias:
## 2.9 ( 1.451513 to 4.348487 )
## ULoA:
## 6.868698 ( 4.304366 to 9.433029 )
## LLoA:
## -1.068698 ( -3.633029 to 1.495634 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 29.5
## Minimum value for average measures: 21
## Maximum value for difference in measures: 18
## Minimum value for difference in measures: 1
##
## Bias: 11.4
## Standard deviation of bias: 5.378971
##
## Standard error of bias: 1.70098
## Standard error for limits of agreement: 3.011332
##
## Bias: 11.4
## Bias- upper 95% CI: 15.24788
## Bias- lower 95% CI: 7.552116
##
## Upper limit of agreement: 21.94278
## Upper LOA- upper 95% CI: 28.75489
## Upper LOA- lower 95% CI: 15.13068
##
## Lower limit of agreement: 0.8572161
## Lower LOA- upper 95% CI: 7.669323
## Lower LOA- lower 95% CI: -5.954891
##
## Derived measures:
## Mean of differences/means: 47.35981
## Point estimate of bias as proportion of lowest average: 54.28571
## Point estimate of bias as proportion of highest average 38.64407
## Spread of data between lower and upper LoAs: 21.08557
## Bias as proportion of LoA spread: 54.06542
##
## Bias:
## 11.4 ( 7.552116 to 15.24788 )
## ULoA:
## 21.94278 ( 15.13068 to 28.75489 )
## LLoA:
## 0.8572161 ( -5.954891 to 7.669323 )
300cfu
## Number of comparisons: 10
## Maximum value for average measures: 65
## Minimum value for average measures: 50.5
## Maximum value for difference in measures: 46
## Minimum value for difference in measures: 9
##
## Bias: 28.2
## Standard deviation of bias: 11.39005
##
## Standard error of bias: 3.601851
## Standard error for limits of agreement: 6.376542
##
## Bias: 28.2
## Bias- upper 95% CI: 36.34795
## Bias- lower 95% CI: 20.05205
##
## Upper limit of agreement: 50.52451
## Upper LOA- upper 95% CI: 64.94925
## Upper LOA- lower 95% CI: 36.09977
##
## Lower limit of agreement: 5.875494
## Lower LOA- upper 95% CI: 20.30023
## Lower LOA- lower 95% CI: -8.549247
##
## Derived measures:
## Mean of differences/means: 48.87212
## Point estimate of bias as proportion of lowest average: 55.84158
## Point estimate of bias as proportion of highest average 43.38462
## Spread of data between lower and upper LoAs: 44.64901
## Bias as proportion of LoA spread: 63.15929
##
## Bias:
## 28.2 ( 20.05205 to 36.34795 )
## ULoA:
## 50.52451 ( 36.09977 to 64.94925 )
## LLoA:
## 5.875494 ( -8.549247 to 20.30023 )
6) Biospot compared to AutoCol :
1 cfu
## Number of comparisons: 10
## Maximum value for average measures: 32.5
## Minimum value for average measures: 2
## Maximum value for difference in measures: 0
## Minimum value for difference in measures: -65
##
## Bias: -33.8
## Standard deviation of bias: 22.95793
##
## Standard error of bias: 7.259936
## Standard error for limits of agreement: 12.85264
##
## Bias: -33.8
## Bias- upper 95% CI: -17.37688
## Bias- lower 95% CI: -50.22312
##
## Upper limit of agreement: 11.19755
## Upper LOA- upper 95% CI: 40.27223
## Upper LOA- lower 95% CI: -17.87714
##
## Lower limit of agreement: -78.79755
## Lower LOA- upper 95% CI: -49.72286
## Lower LOA- lower 95% CI: -107.8722
##
## Derived measures:
## Mean of differences/means: -180
## Point estimate of bias as proportion of lowest average: -1690
## Point estimate of bias as proportion of highest average -104
## Spread of data between lower and upper LoAs: 89.9951
## Bias as proportion of LoA spread: -37.5576
##
## Bias:
## -33.8 ( -50.22312 to -17.37688 )
## ULoA:
## 11.19755 ( -17.87714 to 40.27223 )
## LLoA:
## -78.79755 ( -107.8722 to -49.72286 )
10 cfu
## Number of comparisons: 10
## Maximum value for average measures: 57.5
## Minimum value for average measures: 3
## Maximum value for difference in measures: 93
## Minimum value for difference in measures: -7
##
## Bias: 37.6
## Standard deviation of bias: 37.77477
##
## Standard error of bias: 11.94543
## Standard error for limits of agreement: 21.14761
##
## Bias: 37.6
## Bias- upper 95% CI: 64.62244
## Bias- lower 95% CI: 10.57756
##
## Upper limit of agreement: 111.6386
## Upper LOA- upper 95% CI: 159.4778
## Upper LOA- lower 95% CI: 63.79933
##
## Lower limit of agreement: -36.43855
## Lower LOA- upper 95% CI: 11.40067
## Lower LOA- lower 95% CI: -84.27777
##
## Derived measures:
## Mean of differences/means: 53.49743
## Point estimate of bias as proportion of lowest average: 1253.333
## Point estimate of bias as proportion of highest average 65.3913
## Spread of data between lower and upper LoAs: 148.0771
## Bias as proportion of LoA spread: 25.39218
##
## Bias:
## 37.6 ( 10.57756 to 64.62244 )
## ULoA:
## 111.6386 ( 63.79933 to 159.4778 )
## LLoA:
## -36.43855 ( -84.27777 to 11.40067 )
50 cfu
## Number of comparisons: 10
## Maximum value for average measures: 91.5
## Minimum value for average measures: 21
## Maximum value for difference in measures: 149
## Minimum value for difference in measures: 10
##
## Bias: 77
## Standard deviation of bias: 40.59009
##
## Standard error of bias: 12.83571
## Standard error for limits of agreement: 22.72372
##
## Bias: 77
## Bias- upper 95% CI: 106.0364
## Bias- lower 95% CI: 47.9636
##
## Upper limit of agreement: 156.5566
## Upper LOA- upper 95% CI: 207.9612
## Upper LOA- lower 95% CI: 105.1519
##
## Lower limit of agreement: -2.55658
## Lower LOA- upper 95% CI: 48.84805
## Lower LOA- lower 95% CI: -53.96121
##
## Derived measures:
## Mean of differences/means: 132.5774
## Point estimate of bias as proportion of lowest average: 366.6667
## Point estimate of bias as proportion of highest average 84.15301
## Spread of data between lower and upper LoAs: 159.1132
## Bias as proportion of LoA spread: 48.39323
##
## Bias:
## 77 ( 47.9636 to 106.0364 )
## ULoA:
## 156.5566 ( 105.1519 to 207.9612 )
## LLoA:
## -2.55658 ( -53.96121 to 48.84805 )
100 cfu
## Number of comparisons: 10
## Maximum value for average measures: 77
## Minimum value for average measures: 48.5
## Maximum value for difference in measures: 116
## Minimum value for difference in measures: 59
##
## Bias: 90.6
## Standard deviation of bias: 16.6012
##
## Standard error of bias: 5.249762
## Standard error for limits of agreement: 9.293923
##
## Bias: 90.6
## Bias- upper 95% CI: 102.4758
## Bias- lower 95% CI: 78.72421
##
## Upper limit of agreement: 123.1384
## Upper LOA- upper 95% CI: 144.1627
## Upper LOA- lower 95% CI: 102.114
##
## Lower limit of agreement: 58.06164
## Lower LOA- upper 95% CI: 79.08595
## Lower LOA- lower 95% CI: 37.03732
##
## Derived measures:
## Mean of differences/means: 141.6277
## Point estimate of bias as proportion of lowest average: 186.8041
## Point estimate of bias as proportion of highest average 117.6623
## Spread of data between lower and upper LoAs: 65.07672
## Bias as proportion of LoA spread: 139.2203
##
## Bias:
## 90.6 ( 78.72421 to 102.4758 )
## ULoA:
## 123.1384 ( 102.114 to 144.1627 )
## LLoA:
## 58.06164 ( 37.03732 to 79.08595 )
300 cfu
## Number of comparisons: 10
## Maximum value for average measures: 89.5
## Minimum value for average measures: 55.5
## Maximum value for difference in measures: 96
## Minimum value for difference in measures: 25
##
## Bias: 55.6
## Standard deviation of bias: 20.90827
##
## Standard error of bias: 6.611774
## Standard error for limits of agreement: 11.70516
##
## Bias: 55.6
## Bias- upper 95% CI: 70.55687
## Bias- lower 95% CI: 40.64313
##
## Upper limit of agreement: 96.5802
## Upper LOA- upper 95% CI: 123.0591
## Upper LOA- lower 95% CI: 70.10128
##
## Lower limit of agreement: 14.6198
## Lower LOA- upper 95% CI: 41.09872
## Lower LOA- lower 95% CI: -11.85912
##
## Derived measures:
## Mean of differences/means: 75.79279
## Point estimate of bias as proportion of lowest average: 100.1802
## Point estimate of bias as proportion of highest average 62.12291
## Spread of data between lower and upper LoAs: 81.9604
## Bias as proportion of LoA spread: 67.83764
##
## Bias:
## 55.6 ( 40.64313 to 70.55687 )
## ULoA:
## 96.5802 ( 70.10128 to 123.0591 )
## LLoA:
## 14.6198 ( -11.85912 to 41.09872 )


Under each MicroSurvey configuration, you can change it your desired Welcome Text
Coming Soon...
Coming Soon...
Coming Soon...
You will see the MicroSurvey PopUp in Full Screen and UI elements are intelligently adjusted to fit best on the mobile screen.
Coming Soon...
Coming Soon...
Here. Login --> CX Setup --> Invitation & Tokens --> Tokens & Other Settings --> Micro Survey Setup