TABLE OF INTERACTIONS WITH
APREPITANT
From the French ANSM drug interactions document of September 2016, pp. 35-36
APREPITANT RxNorm: 358255 ATC: A04AD12 |
ANTICONVULSANT ENZYMATIC INDUCERS CLASS CODE: N03A-001 |
Risk of very large decrease of the concentrations of aprepitant |
Not recommended |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
VITAMIN K ANTAGONISTS CLASS CODE: B01AA-001 |
Risk of decrease of the effect of the vitamin K antagonist due to increase of its hepatic metabolism by the aprepitant |
Precaution for use More frequent testing of the INR. Adjustment of the dosage of the vitamin K antagonist during and after the administration of the medications together. |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
CYPROTERONE RxNorm: 3014 ATC: G03HA01 G03HB01 |
Risk of decrease of the concentrations of the cyproterone with risk of lower contraceptive effectiveness |
Precaution for use --In its use as a hormonal contraceptive: Use a reliable contraceptive method, additional or alternative during the time these medications are taken together. |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
COMBINED ESTROGEN-PROGESTIN CONTRACEPTIVES CLASS CODE: G03AB-001 |
Decrease of the concentrations of the estrogen-progestin or of the progestin, with risk of lower contraceptive effectiveness. |
Precaution for use Chose another contraceptive method, in particular a barrier type, during the time these medications are taken together and a cycle following. |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
IFOSFAMIDE RxNorm: 5657 ATC: L01AA06 |
Risk of increase of the neurotoxicity of the ifosfamide |
Take into account |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
ITRACONAZOLE RxNorm: 28031 ATC: J02AC02 |
Increase of the concentrations of aprepitant due to decrease of its hepatic metabolism by the itraconazole. |
Take into account |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
PIMOZIDE RxNorm: 8331 ATC: N05AG02 |
Increased risk of ventricular arrhythmias, especially of torsades de pointes |
CONTRAINDICATION |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
PROGESTIN CONTRACEPTIVES CLASS CODE: G03-001 |
(Except for IUD), decrease of the concentrations of progestin, with risk of lower contraceptive effectiveness. |
Precaution for use Choose another method of contraception, in particular a barrier type, during the administration of these medications together and a cycle after. |
APREPITANT RxNorm: 358255 ATC: A04AD12 |
RIFAMPICIN RxNorm: 9384 ATC: J04AB02 |
Very large decrease of the concentrations of aprepitant |
Not recommended |


Netanyahu indicted for bribery, fraud
Israeli prime minister denies any wrongdoing.
by Paul DallisonIsraeli Prime Minister Benjamin Netanyahu was on Thursday indicted on corruption charges.
Attorney General Avichai Mandelblit issued an indictment charging Netanyahu with fraud, breach of trust and bribery, AP reported.
Netanyahu has denied any wrongdoing and said he is a victim of a witch hunt.
One case against the prime minister involves allegations of receiving gifts from billionaires, allegedly in exchange for favors. In another, Netanyahu is accused of colluding with the country’s top-selling newspaper, Yedioth Ahronoth, to hurt its competition in exchange for favorable coverage. In a third case, Netanyahu is accused of offering incentives to the Israeli telecoms provider Bezeq in exchange for positive stories on an online news website it owns.
In September, Netanyahu and his allies failed to garner a majority of seats in parliament, as Israelis went to the ballot box for the second time in a year following an inconclusive election in April.


@description@
# open a shell and run these commands pxt extract @id@ cd @dirname@ code .
Do you need help installing the tools? Follow these instructions!


| tbl_ptype {dplyr} | R Documentation |
Used in _if
functions to enable type-based selection even when the data
is lazily generated. Should either return the complete tibble, or if that
can not be computed quickly, a 0-row tibble where the columns are of
the correct type.
tbl_ptype(.data)


human origins
How did the modern human mind evolve?
What happened to our cousin species?
What were the lives and stories of our ancestors?
What happened over the last 500 generations?
Who were the people at Blombos Cave?
Or at Bhimbetka, or Lascaux, or Denisova?
How do we have confidence in the answers to any of these questions?
Cousin Species
Neanderthals were living in Europe for something like half a million years until about 40,000 years ago Denisova people, dwarf hominins of Flores, and possibly more
Early Human Evolution
Modern humans from hail from African coasts, the cradle of the human brain Much of our knowledge of humans in prehistory comes from archaeology and in more recent times from genetic analysis
Ideas about how humans evolved
💡 About 75,000 we were still colouring, making beads, learning
chemsitry, maybe even using symbolic language.
Afterwards, better wiring up of the brain came about possibly
through seafood nutrients from diet
💡 There was also a period where an Evolutionary bottleneck
that can be seen within human genome suggesting a population crash
- possibly taking the population to 600 breeding adults
(Multiple) Migrations out of Africa 🌍
Humans then travelled to the edges of the world. The extant diving bajao people of the South Philippines are maybe descendants of a specific such migration ...
Research Material Resources
- Big History Project
- Homo Sapiens: Child of the Ice Age
- World Populations Estimates
- Who We Are and How We Got Here by David Reich
- Early Indians by Tony Joseph
-
Which of us are Aryans?
by Romila Thapar, Michael Witzel,
Jaya Menon, Kai Friese, and Razib Khan - The Ascent of Man by Jacob Bronowski (Documentary)
Research Scientists Working on Human Origins
Chris Stringer, Niobe Thompson, Jayne Wilkins, Christopher Henshilwood, John Parkington, Erika Schagatay, Marta Lahr, Eske Willerslev, Tom Coulthard, Peter Parham, Brian Fagan, Piers Vitebsky


We began as a Moore Girl Scout Robotics FLL (First Lego League) team in the 2011-12 season and competed in FLL for 6 seasons. Throughout our six seasons in FLL we went to state 3 times and won multiple awards in areas such as teamwork and project. A couple of our members were also on a Jr. FLL team (The Sabercubs) for multiple years starting in the 2010-11 season. The Sabercubs won multiple awards at the regional and state level and were one of the 50 teams selected to go to Worlds twice. While at Worlds the Sabercubs won two awards, team spirit and simple machine. In the 2017-18 season The Sabercubs moved up from Jr. FLL to an FLL team.
The 2017-18 Season "Relic Recovery" was our rookie FTC season where we used a basic push bot design with blockly drag and drop code. Despite having technical errors at our first qualifier we earned the Motivate award which earned us a place at State. At state our robot was even better than before and worked a lot more consistently. Despite not advancing to super regionals, we placed 26th of the 41 teams at state in the robot game.
© 2019 Lauren R. Smith


Stacked Dot Plot (ggplot) - Stacked dot plot created using ggplot2 combining paneling, custom annotations and some simple data manipulation.


Chords Transposer
Chords Transposer can manipulate guitar chords in many ways such as Guitar Chords parsing and Transposing.
Usage
- Click parse to filter raw song into chords and song lines.
- Click Transpose G# to transpose song from this scale to given scale (in this scenario G to G#)
- Click Transpose +1 to increase scale by 1 semitone
- Click Transpose -1 to decrease scale by 1 semitone
example #1: | Gm | F | Gm | Eb | | B | F | B | Gm | Gm F Gm Eb B F B Gm Mandaramen eha, dew duwak athi bala B Cm B F Mata yanna denna siyumeliye Suwanda soya soya B Cm B F Me raththriyama nisansalai Gm Eth oba nisa example #2: [Intro] ---------------------------------------- | Eb | - | Ab | - | | Eb | - | Cm | Dm | | Fm | - | Cm | Bb | | Eb | [Chorus] ---------------------------------------- Eb Anganavo Bb Eb Geethe Leewa Bb Eb Thaale Damuwa Eb Bb Ab Bb Sihinen mata keewa oba maage kiyala Eb Anganavo Rupikawo Bb Eb Ranguman Ranguwa Bb Eb Mata Ama mee peuwa Bb Ab Bb Eb Inne obe loke dan inne man obage loke
About
Chords Transposer was written by Nadun indunil.


Key: = Must support, = QICore-defined extension, = Is-Modifier
| Field | Card. | Type and Description |
|---|---|---|
| recorder |
0..1
|
Patient | RelatedPerson | Practitioner
|
| category |
0..1
|
code
|
| certainty |
1..1
|
Extension
|
| suspectEntity |
0..*
|
List<SuspectEntity>
|
| code |
1..1
|
Concept
|
| didNotOccur |
0..*
|
List<Extension>
|
| date |
0..1
|
DateTime
|
| identifier |
0..*
|
List<Identifier>
|
| location |
0..1
|
Location
|
| period |
0..*
|
List<Extension>
|
| reaction |
0..*
|
List<Condition>
|
| seriousness |
0..1
|
Concept
|
| subject |
0..1
|
Patient | Practitioner | ResearchSubject | RelatedPerson
|
| type |
0..1
|
Concept
|
| study |
0..*
|
ResearchStudy
|
Key: = Must support, = QICore-defined extension, = Is-Modifier


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--- layout: post title: Carglass TVC date: '2015-11-11T18:30:38+01:00' categories: - Storyboards picture_url: https://film-Storyboards.tumblr.com/post/133034529227 ---


Kim Kardashian cried when Robin Williams compared Met Gala look to Mrs Doubtfire
Kim Kardashian has opened up about feeling ‘insecure’ about her 2013 Met Gala dress, admitting she cried when she saw memes about it.
Safe to say, the memes were a lot less kind than Rise and Shine.
The star, who is known for her bold looks at the event, was worried about how she would look because she was pregnant with her daughter North.
‘I was very pregnant, very puffy and bloated and I was like, “Oh god, of course the first time I go I’m gonna be huge,”‘ she said, explaining that she wasn’t actually invited but went as her husband Kanye West’s plus one.
Designer Riccardo Tisci made sure she was wearing a stretchy fabric to be comfortable, but the public reaction wasn’t quite what she expected.
Of course, memes began to circulate, with even celebs like Robin Williams getting in on the joke.
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‘I think Robin Williams even tweeted it, said I looked like Mrs Doubtfire,’ Kim told Vogue. ‘I was crying the whole way home because I just couldn’t believe it.’
Adding that she would have rather gone with the plain black version of the dress, she said: ‘I could never really speak up at that point because I so shy and just wanted to make everybody happy.’
However, despite the public generally loving her outfit this year, it still wasn’t without a bit of stress on her part, due to a disagreement with Kanye.
A recent episode of Keeping Up With The Kardashians showed a row between Kim and Kanye about the sexiness of the custom corseted Thierry Mugler dress for May’s fashion gala.
The mother-of-four said: ‘Well, the dress initially, since I was wet coming out of the water, there were nipples attached to it. I think with editing I don’t know, I’m not sure if we actually put that part into that fight.
‘So, he was really certain that he didn’t want that on the dress and had mentioned it multiple times. And that was still on there so we did have that discussion.’
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Fake nipples aside, she still looked absolutely stunning.
Got a showbiz story?
If you've got a story, video or pictures get in touch with the Metro.co.uk Entertainment team by emailing us<EMAIL_ADDRESS>calling 020 3615 2145 or by visiting our Submit Stuff page - we'd love to hear from you.


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To start off this assignment I have started hand drawing ideas for my index page and then have followed this up using the moqups site to create a digital wireframe.


|
Welcome to the tutorial section. In this section I will post any tutorials I make. They will be categorized appropriately
and will be listed in their individual sections. Feel free to send me an email if one (or more) of my tutorials are unclear
, confusing or if there are any mistakes since I do these on the fly without much preperation (I usually have a general script
of the topics I will discuss about). Any source code seen in the videos will be listed with it.
Again, please let me know if there is something unclear or if you have any tips on making these tutorials better. Also you'll
have to excuse my horrifying French accent. I am English, just grew up in a very French region of Canada ;)
Also, if you haven't noticed yet. I have a section called "Grey Hat Hacking". DO NOT EMAIL ME ASKING HOW TO HACK YOUR GIRLFRIENDS/BOYFRIENDS
EMAIL ACCOUNT OR ANY OTHER SUCH RETARDED THING; I will post the email with my comments on the website and you might not like that too much.
Also, if you're asking me what Grey Hat means, then you have no business in that section. I've placed a moron filter on the link. So do not
email me asking how to get in the section. If I find that you are genuinely interested, I might give you a hint.
Enjoy!
|


Detection
- Invalid input (such as input that is not consistent with application logic)
- Input that contains non alphanumeric characters or query syntax
- Empty inputs
- Inputs that are too long
- Access to internal pages without authentication
- Bypassing application flow


Perhaps I should mention a few things about my previous drug experiences before continuing, as that might explain a part of my personality which came to influence the experience I am about to describe. The only prior use of mind-altering drugs, including alcohol and tobacco, was some (very infrequent) cannabis smoking. Two of the times it went relatively well, powerful experiences that left me impressed but not particularly enlightened. The third time, however, I smoked an awful lot of it and after that went for a walk in the city. I discovered a few things about fear and paranoia. Usually I am not too comfortable about being near strangers, but under the influence of THC it was a true nightmare, and a reminder of how terribly important the setting can be for a psychedelic experience.
All along I have been looking for a chance to try either LSD or psilocin/psilocybin, but the former is quite rare and expensive in this corner of the world, and nobody around seemed to have any mushrooms either. Then a friend gets hold of some 2C-B, a chemical of which I had heard almost exclusively positive things when used in a somewhat responsible way, so I decide it could serve as an introduction to psychedelic substances other than cannabis.
Unfortunately not everyone has access to sophisticated laboratory equipment, or even accurate scales, but the capules were supposed to contain 25 mg of some 2C-B salt. Since everyone reacts differently, I can neither say I'm sure the effects corresponded to a 25 mg dose, nor that they didn't. There was four of us, after a joint had been passed around and we were all slightly stoned, the other three snorted their 2C-B. Careful as I am, I waited to see if there were going to be any convulsions, heavy bleeding, death or any other of the nasty effects some of 2C-B's cousins may cause. This did not happen, so a while later I swallowed the capsule.
Taking the drug orally, I did not expect any effects to be noticed within at least half an hour, the cannabis fog didn't exactly help when it came to detecting the first signs. To my suprise I noticed the first real effects after what felt like a relatively short period of time, and in retrospect I think the first few hints were noted after 10 or 15 minutes. My perception of time was perhaps not the best, but the onset was more rapid than I expected.
I could not detect any physical effects except impaired motor skills and some numbness. Psychologically I did not expect too much - and that was precisely what happened. Loss of short-term memory and perception of time, mild hallucinations (my arm was melting, things were moving around), closed-eye visions (lots of small, very sharp triangles) and the dream-like feeling that something has happened, I do not know what, but when I open your eyes (or focus on the usual reality) nothing has happened. A reality I can only vaguely sense.
We watched some TV. The faces of people looked very odd, like if they were monsters. In fact they were, as we happened to have turned on some horror movie. Remembering a story I read, about a group of people who went to watch The Ring (one of the few movies that has scared me, I must admit) after having taken LSD, I thought about this. But the movie seemed so ridiculous, I just couldn't stop laughing at it.
I was the one who suggested the walk. Considering none of the others are as uncomfortable with strangers that I am, you can probably tell how 2C-B affects my judgement. What I didn't think about is that everybody doesn't live in the woods, like I do. There were people outside, my enemies, who want to spit on me and put me in jail for no good reason. A young woman approached, suddenly she just moved a long distance in no time and passed us. I could feel her mind looking into mine and discovering the terrible crime I had commited. Soon after that I turned right back.
Later I tried to get back into the familiar reality. For some odd reason this was accomplished by removing my glasses, which are pretty strong. But after a number of seconds things started to get “sharp” again, and my thoughts ran away. The effects were still interesting, but not being able to think a rational thought got annoying. Instead I started to look at my emotions, just to find that there was nothing there. I didn't feel anything. This was certainly not what I expected from the reports I have read, but that was what I saw. Looking back at it, I think that I can see why. If there were no emotions there from the beginning, there is nothing for the drug to work with.
I have read about the uses of 2C-B within psychotherapy, I don't say it can't be useful, but if you go into the experience with the intent of exploring your mind, you might get disappointed. I have used it once more after that, using about the same dose, with similar effects.
One note about long-term effects – I still see those triangles when I close my eyes or look at the clear sky. Not serious enough to qualify as HPPD, but taking large doses of this chemical once a week is nothing I would try.
Experience Reports are the writings and opinions of the individual authors who submit them.
Some of the activities described are dangerous and/or illegal and none are recommended by Erowid.


{% import 'site/macros.html' as macros with context %} {% set comments_are_enabled = post.enable_comments and settings.enable_comments %}
on {{comment.publish_date}}
{{comment.author_name}} Says:


"Charity: An Example of the Believers" by lds.org
Ways to Practice Charity
- Hold the door open for someone.
- Do a chore for someone without them knowing.
- Compliment a friend.
- Help a friend study.
- Donate to charity.
- Smile!
- Volunteer in service activities.
- Call a loved one or friend.
- A simple "thank you".
- Minister in the moment.
- Compliment your roommates.


Welcome to the Slipknot Fan Page
This website highlights the band members of the Iowa-based heavy metal band along with their early beginnings, present accomplishments, and some of their most notable soundtracks.


A toggle button is a special type of button that conveys a pressed or non-pressed state; this state is conveyed programmatically via the aria-pressed attribute. They can be used in single-select or multi-select groups.
These buttons, like all buttons, should NOT contain structural elements, such as headings or lists.
A toggle button can have one of three different layouts: minimal (default), list or gallery.
The default, minimal toggle button should be used when the contents are single-line and very short, as in shoe sizing, for example. This layout is geared more towards allowing the display of many more options and maximizing screen real estate.
NOTE: All toggle button examples utilize JavaScript to toggle the aria-pressed state of the button.
List layout should be used when it's desired to have wider horizontal buttons. These are more easily stackable on narrower screens.
You may use this layout by adding the toggle-button--list-layout modifier to the toggle button.
A subtitle can be added via toggle-button__subtitle block.
To have a multi-line subtitle, you may use a single <p> tag that has longer text or a maximum of two separate <p> tags with shorter text inside the toggle-button__subtitle block.
To add an icon to a toggle button, you can use the toggle-button__icon block.
To add an image to a toggle button, you can use the toggle-button__image-container block using an <img> or as a css background image.
Gallery layout should be used when there will be fewer buttons (as larger buttons take up more screen real estate) and it's desired to have a more vertical/square implementations with more emphasis on graphical elements (images/icons). As such, since the purpose of gallery layout buttons is to exentuate graphical elements, a graphical element (icon or image) is typically required in gallery layout buttons.
You may use this layout by adding the toggle-button--gallery-layout modifier to the toggle button.
To add an image to a toggle button, you can use the toggle-button__image-container block.
Toggle buttons have a mininum and maximum width and are meant to be fluid between those boundaries. If using these buttons separately, you will need to set up their combined high-level layouts on your own. In these examples, their widths are artificially/manually set to various widths to demonstrate how the buttons undergo responsive adjustments.
The image used in these buttons will shrink/grow responsively in width and height based on the overall button width.
These buttons use background-size: contain; for background image scaling/filling.
These buttons use background-size: cover; for background image filling the alloted space. The following buttons have the background image positioning using background-position-y: 20%;. Depending on your specific image, you may also need to adjust the background positioning along the x and y axis to ensure the main focal point remains visible and centered in your implementation.
To add an icon to a toggle button, you can use the toggle-button__icon block.


Bypass Censorship
bypasscensorship.orgBypass Censorship find and promote tools that provide Internet access to everyone.
The site is built by:
- Leyla Avsar (designer)
- Fredrik Jonsson (dev)
The British Broadcasting Corporation (BBC) (UK), Deutsche Welle (DW) (Germany), France Médias Monde (FMM) (France), the U.S. Agency for Global Media (USAGM) (US) and the Open Technology Fund (OTF) (US) co-sponsor the Bypass Censorship website.
Websites of international news agencies are often blocked in many countries. In order to connect people to these sites, Bypass Censorship feature and recommend tools in the following languages: English, French, Spanish, Arabic, Farsi, Chinese, and Russian.
One of the tools is the Bypass Censorship Extension for Firefox and Chrome. The extension help direct people to mirrors of partners sites if they are being censored.
The first version of the site was built in Drupal 8 but it was relaunched as a static site built with Hugo in 2019.
Security, page load time and easy of hosting is the main reasons for switching to a static site. As the lead developer I had good experience with Hugo and was interested in exploring the multilingual features.
It’s a simply site, basically one page in seven languages. I had no problems getting Hugo to output what I wanted. Found the multilingual support straight forward and easy to work with.
Thanks to the design by Leyla Avsar the site also looks good. I used the Hugo Zen theme with a few custom templates and the needed CSS.
The editors can maintain content via Forestry.io CMS or directly via Git. Forestry does unfortunately not have multilingual support. All the language versions are in one pile making it harder to find the right file to edit, but it works.


Create random primes
Prime numbers are used in many cryptographic algorithms. The RSA algorithm for example needs two very big prime numbers for the creation of a secure key pair.
These big prime numbers are usually created with the help of a random number generator.
With this dialog you can generate a list of 10 random prime numbers with either 20, 50 or 100 digits, or even up to 500 digits by using the "n x m digits" input field.


--- layout: null permalink: /setup/ ---
{{ site.description }}
See the elements with dotted borders? Hover your cursor over them to see the variables that set them accordingly.
The download links on the left are generated using site.repository_url
site.title
is shown as the title in tabs. page.title
may be used to overide site.title
page.excerpt
may also be used to add description of page.
To create a navigation bar as the one at the top of the page, you need to place an mapping of titles to relative urls under the key items
in the file _data/menu.yml
For example,
items:
"introduction": "/"
"setup": "/setup/"
You can simply place any markdown files in the docs/
directory for your documentation. They will be automatically converted to HTML.
If need be, you may use HTML files instead.
A Sample file would be: (docs/sample.md)
---
layout: default
permalink: /endpoint
---
# markdown
I shall write this in Markdown only.
You may remove docs/setup.html
and script/
as they are not required for deployment.


{% style "/css/screen.css" %}
Bob's Blog
Home
Kids
Resume
Projects
Dippybird - Clojure webapp for blogging
Judge - Clojure webapp for judging a science fair
Sciencefair - Clojure webapp - Groton Dunstable Elementary School science fair web site
Notes - Clojure webapp - A simple wiki
CarCast - Android Podcast Downloader/Player
jbum - Java Swing photo web page builder
jblog - Simple Java/JSP based blogging platform
About
{% block content %} {% endblock %}
{% block page-scripts %} {% endblock %}


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We would love to hear your feedback!
Please send your feedback to
support@whatcaniwatch.com


Before Change
cv = model_selection.SlidingWindowForecastCV(window_size=100, step=24, h=1)
// store the residuals for each model
m1_residuals = []
m2_residuals = []
for train_window_indices, val_index in cv.split(train):
tr_fold = train[train_window_indices]
model1.fit(tr_fold)
model2.fit(tr_fold)
m1_residuals.append(train[val_index] - model1.predict(n_periods=1))
m2_residuals.append(train[val_index] - model2.predict(n_periods=1))
// make sure residuals are flat and compute RMSE
rmse = lambda arr: np.sqrt(np.average(utils.check_endog(arr) ** 2))
After Change
model2, train, scoring="mean_squared_error", cv=cv, verbose=2)
// Pick based on which has a lower mean error rate
m1_average_error = np.average(model1_cv_scores)
m2_average_error = np.average(model2_cv_scores)
errors = [m1_average_error, m2_average_error]
models = [model1, model2]


Automatically analyzing your deployed application against its predecessor is critical to the success of your customers.
With this service, you simply provide a link to your cluster, and it will assess if performance has degraded, giving you back a response in seconds.
If you click on the hyperlink above, you'll get back a JSON document detailing a set of canary checks performed against an application cluster.
Related:


DfE enquiries
Central newsdesk 020 7783 8300
General enquiries 0370 000 2288
Press release
New focus on the highest quality qualifications and more information to be published in transparent school league tables.
The Department for Education today announced that only the highest quality qualifications will be included in new, transparent school league tables.
Today’s reforms follow Professor Alison Wolf’s review of vocational education. They will ensure schools focus on valued qualifications that make it easier for young people to enter good jobs or go on to higher education.
All 14-16 qualifications currently count in performance tables whether or not they include external assessment. From 2014 only GCSEs and valued vocational qualifications that meet strict new criteria will be recognised in the tables. All these qualifications will count equally. At the moment, some qualifications are worth as much as six GCSEs in the tables.
Schools will retain the freedom to offer any qualification approved for 14- to 16-year-olds. Teachers will still be able to use their professional judgement to offer the qualifications which they believe are right for their pupils. But only the most rigorous will count in league tables.
A consultation, to run until the end of September, will help define the rules governing high-quality qualifications.
We propose that all full-course GCSEs, established iGCSEs and AS levels should continue to count in the tables.
We also propose that other qualifications should only count if:
When the consultation ends a list of qualifications which will feature in future performance tables will be drawn up.
In order to ensure that students are encouraged to follow a balanced curriculum which encourages progress, only two non-GCSEs will be allowed to count towards the existing five A*-C GCSE indicators.
The Wolf Report demonstrated that the current performance table system creates perverse incentives. Schools have been tempted to teach qualifications which attract the most points in the performance tables - not the qualifications that will support young people to progress.
Professor Alison Wolf said:
Pupils need to acquire the broad skills which will enable them to progress in the short term, and to thrive over a lifetime of worldwide economic and industrial change.
The Government needs to give schools every incentive possible to offer the programmes and qualifications which will achieve this end. In recent years though, schools have been under enormous pressure to pile up league table points. When any qualification under the English sun can contribute these, the pernicious effects are obvious.
We need a single list of good qualifications which all have the same key structural characteristics, but cover a wide range of content. They need to be stretching, standardised, and to fit easily into a typical pupil’s programme and into a school’s overall timetable.
Schools Minister Nick Gibb said:
Young people should be taking only the best qualifications in academic and vocational subjects that allow them to progress.
Reforming the league tables so that they include only those qualifications that allow young people to maximise their potential is long overdue.
The Department for Education’s annual Statement of Intent, published today, sets out the key indicators against which a school’s performance will be judged. This data will be published in January 2012 alongside a wider set of information, including school spending and pupil cohort data, as part of the Government’s commitment to greater transparency in January 2012.
The 2011 school league tables will highlight the performance and progress of disadvantaged groups compared with other pupils. This will create a powerful incentive to narrow the gap in achievement between richer and poorer pupils.
The league tables will also include attainment data, progress measures and an extensive range of additional information on progress made by low, medium and high attainers. There will also be data on those receiving free school meals and looked-after children. Together this will place a much greater focus on what schools are doing to help all their pupils fulfil their potential.
Schools Minister Nick Gibb said:
Parents want more information so they can judge schools’ performance. The changes we have made mean that parents will have a complete picture of their local schools so they can choose the right school for their child. These changes will also ensure schools do an even better job in helping vulnerable children to succeed.
The Statement of Intent states that the make-up of the English Baccalaureate - a mark of achievement for GCSE-stage pupils - will stay the same. Pupils’ results will count towards the EBacc measure if they achieve a C or better in each of English, maths, geography or history, the sciences and a language (modern or ancient).
For secondary schools where Key Stage 4 exam results for Year 11 pupils are published, the definitions will be based on Key Stage 2 test results attained by pupils at the end of primary school:
For primary schools where we publish Key Stage 2 test results for Year 6 pupils, the definitions will be based on Key Stage 1 results attained by pupils at the end of the infant phase:
The detailed make-up is:
In addition to GCSE the following exams in the above subjects also count:
Central newsdesk 020 7783 8300
General enquiries 0370 000 2288
Published: 20 July 2011


INNOVATIVE TECHNOLOGY PROTOCOL $ITP
We're building the world's first E-commerce platform, where you can BUY/SELL products using cryptocurrencies. The project is under development phase and the launch dates will be updated soon.
We're building the world's first E-commerce platform, where you can BUY/SELL products using cryptocurrencies. The project is under development phase and the launch dates will be updated soon.


Global
home
Polymer component
Angular component
React component
Extra actions
reset store
remove id
{{item.key}}
x


This week we learned how to style our websites with CSS. One important concept to understand is how you use padding, margin and border. Lets imagine that all HTML elements are wrapped in a box. The box consists of: margins, borders, padding areas and the content (text, image etc) The padding area of an element is the horizontal and vertical space that’s set around the actual content. The border area extends the padding area to the area containing the borders of the element. Margin is the space outside the border of that element. If elements have no margins around them, they will bump right up against each other.


apple
mango
Croissants | Flour and Stones
Croissants | Flour and Stones
Croissants | Flour and Stones
Croissants | Flour and Stones
Croissants | Flour and Stones
Croissants | Flour and Stones


Legal Notice
This documentation is distributed under an open source license. You may review the terms of this license at: http://www.oracle.com/technetwork/database/berkeleydb/downloads/jeoslicense-086837.html
Oracle, Berkeley DB, Berkeley DB Java Edition and Sleepycat are trademarks or registered trademarks of Oracle. All rights to these marks are reserved. No third-party use is permitted without the express prior written consent of Oracle.
Java™ and all Java-based marks are a trademark or registered trademark of Sun Microsystems, Inc, in the United States and other countries.
Other names may be trademarks of their respective owners.
To obtain a copy of this document's original source code, please submit a request to the Oracle Technology Network forum at: https://forums.oracle.com/forums/forum.jspa?forumID=273
1-Feb-2017
Table of Contents


Ninya.io
LOCATION
SKILLS
Those are the top AngularJS developers from London
Those are the top Node.js developers from London
Those are the top JavaScript developers from London
Those are the top AngularJS developers from San Francisco
Those are the top Node.js developers from San Francisco
Those are the top JavaScript developers from San Francisco
Those are the top AngularJS developers from Berlin
Those are the top Node.js developers from Berlin
Those are the top JavaScript developers from Berlin
Those are the top AngularJS developers from Hamburg
Those are the top Node.js developers from Hamburg
Those are the top JavaScript developers from Hamburg
Those are the top AngularJS developers from Germany
Those are the top Node.js developers from Germany
Those are the top JavaScript developers from Germany
Those are the top AngularJS developers from Birmingham
Those are the top Node.js developers from Birmingham
Those are the top JavaScript developers from Birmingham
Results
from
{{user.location}}
with reputation
{{user.reputation}}


cubic-bezier in js
run
css3 ease-out in js
css3 ease-out
js easeOut
js cubic-bezier(1,0.22,0,0.84)
css3 cubic-bezier(1,0.22,0,0.84)


I built the Quip Ecommerce platform, named a Top 25 Invention by
Time Magazine in 2016.
Coding bootcamp and learning management system.
Eventbrite is the leading event management platform on the web
with millions of individuals utilizing their applications to
find, register or, and management events in numerous industries.
Shop Hacker allows you to easily import digital products such as
elearning courses, software, and games directly into your
ecommerce store.
Online tutorials and productivity tips.
Keep track of what you learn every day.
What you track improves. DashTrack is a journal that makes it
easy to track your daily tasks and make the most of your time
each day.
Online shop for developer happiness.
Online technology tutorials.

Publish and share daily devotionals.
Easy way to manage the digital life of your bar or restaurant.


Collocation
collocation: a combination of words in a language, that happens very often and more frequently than would happen by chance 词组；组合
B
bona fide: 真诚的；真实的；合法的 genuine, real or legal; not false
- a bona fide reason 真正原因
-
Is it a bona fide, reputable organization?
这是不是个合法的、值得信赖的机构？
by and large:大体上；总的来说；基本上 used for referring to something in a very general way; when everything about a situation is considered together
- by and large, that information is accurate
- There are a few small things that I don't like about my job, but by and large it's very enjoyable.
- By and large, the people of this state are not happy with the governor's policies.
D
de facto: 实际上存在的（不一定合法）existing in fact, although perhaps not intended, legal, or accepted
- The city is rapidly becoming the de facto centre of the financial world.
- He's her de facto husband though they're not actually married.
- English is de facto the common language of much of the world today.
-
The general took de facto control of the country.
这位将军实际上控制了整个国家。
H
hit the mark: 达到目的；打中要害 to achieve/not achieve the result that you intended
-
Their discussions were impractical and did not hit the mark.
他们的讨论全是空谈，根本没有切中问题关键！
P
per se: 本身；本质 上 used meaning ‘by itself' to show that you are referring to sth on its own, rather than in connection with other things
- Research shows that it is not divorce per se that harms children, but the continuing conflict between parents.
-
The drug is not harmful per se, but is dangerous when taken with alcohol.
这种药本身无害，但与酒同服就危险了。
S
state-of-the-art: 应用最先进技术（或方法）的；最先进的 very modern and using the most recent ideas and methods
- a state-of-the-art computer
- The control panel uses all the newest technology and is considered state-of-the-art.


Thomas Rhett to perform at 2019 American Music Awards on ABC
by WABCLOS ANGELES -- Country music superstar Thomas Rhett will take the stage at the American Music Awards later this month, the show announced Friday.
Rhett's performance will cap a busy year for the performer, who is also nominated favorite male country artist. In May, Rhett released his fourth studio album, "Center Point Road," which debuted at the top of the Billboard Top 200 Albums chart and marked the highest streaming debut for a country album ever.
His AMA performance also comes amid his ongoing work with Wells Fargo to raise awareness for the company's Holiday Food Bank initiative benefiting Feeding America. Rhett will volunteer with Wells Fargo employees at a local food bank prior to his American Music Awards performance.
Taylor Swift, Selena Gomez, Camila Cabello, Dua Lipa, Lizzo and Billie Eilish were previously announced as performers. Swift, who will receive the Artist of the Decade award, is set to put on "an unprecedented performance celebrating the biggest hits of her career."
The 2019 American Music Awards will air Sunday, Nov. 24, at 8 p.m. ET/PT | 7 p.m. CT on ABC. Click here to see a full list of 2019 American Music Awards nominees.
Fans can vote for their favorite artists until Wednesday, Nov. 20, 2019, at 11:59:59 p.m. PT. by visiting goo.gle/AMAsVote or by going to Google.com and using the search terms "AMAs Vote" or "[Nominee Name] AMAs Vote."


view all...In Japanese history, a ninja is an elite warrior, highly trained in all aspects of combat martial arts, and specializing in a variety of unorthodox arts of war. The methods used by ninja included assassination, espionage, stealth, camouflage, unconventional warfare, specialized weapons, and a vast array of martial arts. Their exact origins are still unknown. Their roles may have included sabotage, espionage, scouting and assassination missions as a way to destabilize and cause social chaos in enemy territory or against an opposing ruler, perhaps in the service of their feudal rulers (daimyo, shogun), or an underground ninja organization waging guerilla warfare.


1.) Pick the elements you want to use in your prompt.
1.) Pick the elements you want to use in your prompt.
2.) Select colors and rearrange elements here.
3.) Preview the output.
24-bit Colors
256 Colors
16 Colors
4.) Copy and paste the code into your bashrc.


A couple of weeks ago I ran into a problem where I needed to create some spatially correlated data for a project and I realized that I didn’t know the first thing about how to go about doing it. I was lucky to find that the paper that I was trying to replicate did a great job of detailing their methods in such a way that I was able to create some spatial data of my own. The idea is that you need to create a covariance matrix of the relationships of your data to pull form a multivariate random normal distribution.
is just the scalar mean and can be set to any real number but defining a sensible covariance matrix was originally difficult. The way that Riebler et al. did it was by using a matrix Q
where is the number of neighbors a location has and means that the two locations are adjacent. Im used to working with spatial polygons data frames in R and found that its pretty easy to create this matrix with the right packages. Here’s an example with US state shape file.
library(sp)
library(surveillance)
library(spdep)
library(MASS)
# load in some USA data to work with
load(url("http://biogeo.ucdavis.edu/data/gadm2/R/USA_adm2.RData"))
cont_usa_locs <- c("Texas", "Louisiana")
# spatial polygons data frame to simulate from
cont_usa <- gadm[(gadm@data$NAME_1 %in% cont_usa_locs),]
cont_usa$ID <- 1:length(cont_usa)
# adjacency matrix for spatial data 1's if adjacent 0 otherwise
adjmat <- poly2adjmat(cont_usa)
# Create Q from an adjacency matrix
n_delta_i <- rowSums(adjmat)
Q <- adjmat * -1
diag(Q) <- n_delta_i
Using the inverse of Q as the covariance matrix creates a smooth spatial dispersion, that you can see below, when compared to just simple dispersion at random. A more complete example can be found here.


@* * Copyright 2010-2013 Artima, Inc. * * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. *@ @userGuidePage("Tagging your tests") {
ScalaTest allows you to define arbitrary test categories, to "tag" tests as belonging to those categories, and filter tests to run based on their tags. For example, you could tag some tests as being slow and chose to exclude the slow tests during some runs. ScalaTest supports one tag by default: ignore. You can tag a test as ignored to "switch it off" temporarily.
To support the common use case of “temporarily” disabling a test, with the
good intention of resurrecting the test at a later time, each style trait provides a way to tag tests as ignored.
For example, in a FlatSpec
you can change an it
or an in
to ignore
:
import org.scalatest.FlatSpec import scala.collection.mutable.Stack
class StackSpec extends FlatSpec {
"A Stack" should "pop values in last-in-first-out order" in { val stack = new Stack[Int] stack.push(1) stack.push(2) assert(stack.pop() === 2) assert(stack.pop() === 1) }
ignore should "throw NoSuchElementException if an empty stack is popped" in { val emptyStack = new Stack[String] intercept[NoSuchElementException] { emptyStack.pop() } } }
If you run this version of StackSpec
in the Scala interpreter with:
scala> (new StackSpec).execute()
It will run only the first test and report that the second test was ignored:
A Stack - should pop values in last-in-first-out order - should throw NoSuchElementException if an empty stack is popped !!! IGNORED !!!
Each style trait provides a way to tag tests. To tag tests in a FlatSpec
, for example,
you pass objects that extend abstract class org.scalatest.Tag
to taggedAs
just before the in
. Class Tag
takes one parameter, a string name.
Here's how you might define tags to mark tests that are slow or require a database:
import org.scalatest.Tag
object SlowTest extends Tag("com.mycompany.tags.SlowTest") object DbTest extends Tag("com.mycompany.tags.DbTest")
Given these definitions, you could tag FlatSpec
tests like this:
import org.scalatest.FlatSpec
class ExampleSpec extends FlatSpec {
"The Scala language" must "add correctly" taggedAs(SlowTest) in { val sum = 1 + 1 assert(sum === 2) }
it must "subtract correctly" taggedAs(SlowTest, DbTest) in { val diff = 4 - 1 assert(diff === 3) } }
This code marks both tests with the com.mycompany.tags.SlowTest
tag,
and test "The Scala language should subtract correctly"
with the com.mycompany.tags.DbTest
tag.
When executing a suite, tests can optionally be included and/or excluded (i.e., filtered) based on their tags. Here's how:
Next, learn about running your tests.


Trump, GOP lawmakers, not on same page for impeachment defense
by Jamie DupreeJust days before impeachment hearings are set to begin the U.S. House, President Donald Trump and Republicans in Congress continued to be on different pathways when it comes to defending the President's conduct, as Mr. Trump on Sunday again maintained that he did nothing wrong in his phone call with the leader of Ukraine.
"The call to the Ukrainian President was PERFECT," Mr. Trump tweeted from Trump Tower in New York. "Read the Transcript!"
But Democrats said the transcript showed behavior which was not acceptable - and there were some GOP lawmakers agreeing in part.
"I believe it was inappropriate," Rep. Mac Thornberry (R-TX) said of the President's request in a July phone call for the government of Ukraine to launch investigations which would have benefited Mr. Trump politically.
"I do not believe it was impeachable," Thornberry said on ABC's "This Week."
Mr. Trump argued specifically against that.
"Republicans, don’t be led into the fools trap of saying it was not perfect, but is not impeachable," he tweeted.
The White House document detailing the call - which is not a full, word for word transcript - shows the President clearly asking the leader of Ukraine to investigate the son of Vice President Biden, along with probing the assertion that Ukraine - and not Russia - had hacked Democrats in the 2016 elections.
[Caption]
While the White House and Republicans tried to sort out their impeachment arguments, Democrats were blasting the GOP.
"Witness testimony shows that everybody involved in the President’s pressure campaign knew what he wanted," said Rep. Mike Quigley (D-I), "political investigations to undermine our free and fair elections."
"Republicans cried for weeks for open & public impeachment inquiry hearings," said Rep. Nanette Barragan (D-CA). "Now that public hearings begin this week, Trump & GOP don’t want them."


06 November 1998
Disease Outbreak Reported
Hurricane Mitch and associated flooding have affected 3-5 million persons in Central America, and caused an unknown number of deaths. Although epidemics are relatively rare in the aftermath of natural disasters, in this case there is a combination of high-risk factors which could lead to an increase in the transmission of communicable diseases: the magnitude of the hurricane, the large number of displaced persons, the contamination of drinking-water and poor sanitation conditions.
Even though the mosquito population may decrease (washing effect of the storm) in the first weeks following the hurricane, it will inevitably rebound due to the subsequent accumulation of stagnant water. This could lead to an increased risk of malaria and dengue epidemics in an area that is already highly endemic for these diseases.
Cholera is also endemic in Central America, and again the risk of transmission is likely to increase. Information regarding suspected cases of cholera in the suburbs of Managua (Nicaragua) has recently been received from field workers.
Although no epidemic has been confirmed so far, WHO strongly recommends that relief agencies pay particular attention to epidemic readiness and water safety activities.


| Package | Description |
|---|---|
| sorcer.co.tuple | |
| sorcer.core.context | |
| sorcer.core.signature | |
| sorcer.eo | |
| sorcer.service | |
| sorcer.util |
| Modifier and Type | Class and Description |
|---|---|
class |
Args
Extracted from sorcer.eo.operator
|
class |
Complement<T1,T2>
Extracted from operator
|
class |
DataEntry<T2>
Extracted from operator
|
class |
Entry<T1,T2> |
class |
IndexedTriplet<T> |
class |
InEntry<T>
extracted from operator
|
class |
InoutEntry<T>
Extracted from operator
|
class |
OutEntry<T>
Extracted from operator
|
class |
ParameterTypes |
class |
Path<T2> |
class |
StrategyEntry |
class |
target
Extracted from operator
|
class |
Tuple2<T1,T2> |
class |
Tuple3<T1,T2,T3> |
| Modifier and Type | Class and Description |
|---|---|
class |
ControlContext |
| Modifier and Type | Method and Description |
|---|---|
T |
ServiceContext.doGetReturnValue(ReturnPath<T> path,
Parameter... entries) |
T |
ServiceContext.getReturnJobValue(Parameter... entries) |
T |
ServiceContext.getReturnValue(Parameter... entries) |
T |
ServiceContext.getValue(Parameter... entries) |
T |
ServiceContext.getValue(String path,
Parameter... entries) |
Object |
AssociativeContext.getValue(String path,
Parameter... parameters) |
ServiceContext |
ServiceContext.substitute(Parameter... entries) |
| Modifier and Type | Class and Description |
|---|---|
class |
EvaluationSignature |
class |
NetSignature |
class |
ObjectSignature |
class |
ServiceSignature |
| Modifier and Type | Method and Description |
|---|---|
static Object |
operator.exec(Context context,
Parameter... entries) |
static Object |
operator.exec(Exertion exertion,
Parameter... entries) |
static <T extends Exertion> |
operator.exert(Exertion input,
Parameter... entries) |
static <T extends Exertion> |
operator.exert(T input,
Transaction transaction,
Parameter... entries) |
static Revaluation |
operator.revaluable(Revaluation evaluation,
Parameter... entries)
Makes this Revaluation revaluable, so its return value is to be again
evaluated as well.
|
static Object |
operator.revalue(Evaluation evaluation,
String path,
Parameter... entries) |
static Object |
operator.revalue(Object object,
Parameter... entries) |
static Evaluation |
operator.substitute(Evaluation evaluation,
Parameter... entries)
Returns the Evaluation with a realized substitution for its arguments.
|
static <T> T |
operator.value(Evaluation<T> evaluation,
Parameter... entries) |
static <T> T |
operator.value(Evaluation<T> evaluation,
String evalSelector,
Parameter... entries) |
static <T> T |
operator.value(Exertion evaluation,
Parameter... entries) |
| Modifier and Type | Interface and Description |
|---|---|
interface |
Signature
|
interface |
Strategy |
| Modifier and Type | Class and Description |
|---|---|
class |
ReturnPath<T>
Extracted from sorcer.service.Signature
|
| Modifier and Type | Method and Description |
|---|---|
static Object |
ExertionExecutor.exec(Exertion exertion,
Parameter... entries) |
Exertion |
Exerter.exert(Exertion xrt,
Parameter... entries) |
Exertion |
Exerter.exert(Exertion xrt,
Transaction txn,
Parameter... entries) |
Exertion |
ServiceExertion.exert(Parameter... entries) |
Exertion |
Exertion.exert(Parameter... entries) |
<T extends Exertion> |
ServiceExertion.exert(Transaction txn,
Parameter... entries) |
<T extends Exertion> |
Exertion.exert(Transaction txn,
Parameter... entries)
Sends this exertion to the assigned service provider if set.
|
Exertion |
ServiceExertion.exert(Transaction txn,
String providerName,
Parameter... entries) |
static <T extends Exertion> |
ExertionExecutor.exert(T input,
Transaction transaction,
Parameter... entries) |
static Exertion |
ExertionExecutor.exertOpenTask(Exertion exertion,
Parameter... entries) |
T |
Context.getReturnValue(Parameter... entries) |
Object |
ServiceExertion.getValue(Parameter... entries) |
T |
Evaluation.getValue(Parameter... entries)
Returns the current value of this evaluation.
|
T |
Context.getValue(String path,
Parameter... entries)
Returns an evaluated value of the key object.
|
Object |
ServiceExertion.invoke(Context context,
Parameter... entries) |
T |
Invocation.invoke(Context context,
Parameter... entries) |
Object |
ServiceExertion.invoke(Parameter... entries) |
T |
Invocation.invoke(Parameter... entries) |
ServiceExertion |
ServiceExertion.substitute(Parameter... entries) |
Evaluation<T> |
Evaluation.substitute(Parameter... entries)
Realizes the substitution for this evaluation with respect to the provided parameters.
|
static <T> T |
Evaluator.value(Evaluation<T> evaluation,
Parameter... entries) |
| Modifier and Type | Method and Description |
|---|---|
Exertion |
ExertProcessor.exert(Exertion xrt,
Parameter... entries) |
Exertion |
ExertProcessor.exert(Exertion xrt,
Transaction txn,
Parameter... entries) |
Exertion |
ExertProcessor.exert(Parameter... entries) |
Exertion |
ExertProcessor.exert(Transaction txn,
String providerName,
Parameter... entries) |
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