| Package | flare.physics |
| Class | public class Simulation |
| Property | Defined by | ||
|---|---|---|---|
| bounds : Rectangle Sets a bounding box for particles in this simulation.
| Simulation | ||
| dragForce : DragForce
[read-only] The default drag force for this simulation.
| Simulation | ||
| gravityForce : GravityForce
[read-only] The default gravity force for this simulation.
| Simulation | ||
| nbodyForce : NBodyForce
[read-only] The default n-body force for this simulation.
| Simulation | ||
| objectPoolLimit : int = 5000 [static] The maximum number of items stored in a simulation object pool.
| Simulation | ||
| particles : Array [read-only]
Returns the particle list.
| Simulation | ||
| springForce : SpringForce
[read-only] The default spring force for this simulation.
| Simulation | ||
| springs : Array [read-only]
Returns the spring list.
| Simulation |
| Property | Defined by | ||
|---|---|---|---|
| _ppool : Array [static]
| Simulation | ||
| _spool : Array [static]
| Simulation |
| Method | Defined by | ||
|---|---|---|---|
|
Simulation(gx:Number = 0, gy:Number = 0, drag:Number = 0.1, attraction:Number = -5)
Creates a new physics simulation.
| Simulation | ||
|
Adds a custom force to the force simulation.
| Simulation | ||
|
addParticle(mass:Number, x:Number, y:Number):Particle
Adds a new particle to the simulation.
| Simulation | ||
|
Adds a spring to the simulation
| Simulation | ||
|
eval():void
Evaluates the set of forces in the simulation.
| Simulation | ||
|
getForceAt(idx:int):IForce
Returns the force at the given index.
| Simulation | ||
|
removeParticle(idx:uint):Boolean
Removes a particle from the simulation.
| Simulation | ||
|
removeSpring(idx:uint):Boolean
Removes a spring from the simulation.
| Simulation | ||
|
tick(dt:Number = 1):void
Advance the simulation for the specified time interval.
| Simulation |
| Method | Defined by | ||
|---|---|---|---|
|
getParticle(mass:Number, x:Number, y:Number):Particle
[static]
Returns a particle instance, pulling a recycled particle from the
object pool if available.
| Simulation | ||
|
[static]
Returns a spring instance, pulling a recycled spring from the
object pool if available.
| Simulation | ||
|
reclaimParticle(p:Particle):void
[static]
Reclaims a particle, adding it to the object pool for recycling
| Simulation | ||
|
reclaimSpring(s:Spring):void
[static]
Reclaims a spring, adding it to the object pool for recycling
| Simulation |
| bounds | property |
bounds:Rectangle
[read-write]Sets a bounding box for particles in this simulation. Null (the default) indicates no boundaries.
Implementation public function get bounds():Rectangle
public function set bounds(value:Rectangle):void
| dragForce | property |
dragForce:DragForce
[read-only]The default drag force for this simulation.
Implementation public function get dragForce():DragForce
| gravityForce | property |
gravityForce:GravityForce
[read-only]The default gravity force for this simulation.
Implementation public function get gravityForce():GravityForce
| nbodyForce | property |
nbodyForce:NBodyForce
[read-only]The default n-body force for this simulation.
Implementation public function get nbodyForce():NBodyForce
| objectPoolLimit | property |
public static var objectPoolLimit:int = 5000
The maximum number of items stored in a simulation object pool.
| particles | property |
particles:Array
[read-only]Returns the particle list. This is the same array instance backing the simulation, so edit the array with caution.
Implementation public function get particles():Array
| _ppool | property |
protected static var _ppool:Array
| _spool | property |
protected static var _spool:Array
| springForce | property |
springForce:SpringForce
[read-only]The default spring force for this simulation.
Implementation public function get springForce():SpringForce
| springs | property |
springs:Array
[read-only]Returns the spring list. This is the same array instance backing the simulation, so edit the array with caution.
Implementation public function get springs():Array
| Simulation | () | constructor |
public function Simulation(gx:Number = 0, gy:Number = 0, drag:Number = 0.1, attraction:Number = -5)
Creates a new physics simulation.
Parametersgx:Number (default = 0 ) — the gravitational acceleration along the x dimension
|
|
gy:Number (default = 0 ) — the gravitational acceleration along the y dimension
|
|
drag:Number (default = 0.1 ) — the default drag (viscosity) co-efficient
|
|
attraction:Number (default = -5 ) — the gravitational attraction (or repulsion, for
negative values) between particles.
|
| addForce | () | method |
public function addForce(force:IForce):void
Adds a custom force to the force simulation.
Parametersforce:IForce — the force to add
|
| addParticle | () | method |
public function addParticle(mass:Number, x:Number, y:Number):Particle
Adds a new particle to the simulation.
Parametersmass:Number — the mass (charge) of the particle
|
|
x:Number — the particle's starting x position
|
|
y:Number — the particle's starting y position
|
Particle —
the added particle
|
| addSpring | () | method |
public function addSpring(p1:Particle, p2:Particle, restLength:Number, tension:Number, damping:Number):Spring
Adds a spring to the simulation
Parametersp1:Particle — the first particle attached to the spring
|
|
p2:Particle — the second particle attached to the spring
|
|
restLength:Number — the rest length of the spring
|
|
tension:Number — the tension of the spring
|
|
damping:Number — the damping (friction) co-efficient of the spring
|
Spring —
the added spring
|
| eval | () | method |
public function eval():void
Evaluates the set of forces in the simulation.
| getForceAt | () | method |
public function getForceAt(idx:int):IForce
Returns the force at the given index.
Parametersidx:int — the index of the force to look up
|
IForce —
the force at the specified index
|
| getParticle | () | method |
protected static function getParticle(mass:Number, x:Number, y:Number):Particle
Returns a particle instance, pulling a recycled particle from the object pool if available.
Parametersmass:Number — the mass (charge) of the particle
|
|
x:Number — the particle's starting x position
|
|
y:Number — the particle's starting y position
|
Particle —
a particle instance
|
| getSpring | () | method |
protected static function getSpring(p1:Particle, p2:Particle, restLength:Number, tension:Number, damping:Number):Spring
Returns a spring instance, pulling a recycled spring from the object pool if available.
Parametersp1:Particle — the first particle attached to the spring
|
|
p2:Particle — the second particle attached to the spring
|
|
restLength:Number — the rest length of the spring
|
|
tension:Number — the tension of the spring
|
|
damping:Number — the damping (friction) co-efficient of the spring
|
Spring —
a spring instance
|
| reclaimParticle | () | method |
protected static function reclaimParticle(p:Particle):void
Reclaims a particle, adding it to the object pool for recycling
Parametersp:Particle — the particle to reclaim
|
| reclaimSpring | () | method |
protected static function reclaimSpring(s:Spring):void
Reclaims a spring, adding it to the object pool for recycling
Parameterss:Spring — the spring to reclaim
|
| removeParticle | () | method |
public function removeParticle(idx:uint):Boolean
Removes a particle from the simulation. Any springs attached to the particle will also be removed.
Parametersidx:uint — the index of the particle in the particle list
|
Boolean — true if removed, false otherwise.
|
| removeSpring | () | method |
public function removeSpring(idx:uint):Boolean
Removes a spring from the simulation.
Parametersidx:uint — the index of the spring in the spring list
|
Boolean — true if removed, false otherwise
|
| tick | () | method |
public function tick(dt:Number = 1):void
Advance the simulation for the specified time interval.
Parametersdt:Number (default = 1 ) — the time interval to step the simulation (default 1)
|


>Non-categorized grid list using non-TreeStore also supported. Footer with expand/collapse buttons omitted
>Touch column headers to sort ASC/DESC
>Rapid scrolling and sorting for 265 rows
>Alternate row shading and custom CSS to support row selection
>Example of custom "style" renders to display positve as green and negative as red


YO MAYNE! Darth Vader is luke sky's father manye!!! fa realz.
luke and leia are siblins yo.
7MongoDB is a database. MongoDB's great manual is the place to get started with NoSQL and MongoDB.
Express is an app server. Check out The Express Guide or StackOverflow for more info.
AngularJS is web app framework. Angular's website offers a lot. The Thinkster Popular Guide and Egghead Videos are great resources.
Node.js is a web server. Node's website and this stackOverflow thread offer excellent starting points to get to grasps with node.
Once you're familiar with the foundation technology, check out the MEAN.JS Documentation:


{% extends 'portal.html' %} {% block title %}{{assessment}} | Endpoints | HAWC {% endblock title %} {% block breadcrumbs %}
| Data type | Study summary | Outcome/Results | Outcome/Results + Doses |
|---|---|---|---|
| Bioassay | Study summary | Endpoints | Endpoints + Doses |
| Bioassay (including unpublished HAWC data) | Study summary | Endpoints | Endpoints + Doses |
| Epidemiology | Study summary | Results | N/A |
| Epidemiology (including unpublished HAWC data) | Study summary | Results | N/A |


A small adjustable gas burner used in laboratories. Named after Robert Bunsen.
A thin glass tube closed at one end, used to hold small amounts of material for laboratory testing or experiments.
A rack use to carry certain numbers of test tube.
A tube or pipe that is wide at the top and narrow at the bottom, used for guiding liquid or powder into a small opening.
A conical, flat-bottomed laboratory flask with a narrow neck. late 19th cent.: named after Emil Erlenmeyer (1825–1909), German chemist.
An instrument for measuring and indicating temperature, typically one consisting of a narrow, hermetically sealed glass tube marked with graduations and having at one end a bulb containing mercury or alcohol that expands and contracts in the tube with heating and cooling.
A lamp use burn material in a certain temperature.
A wire gauze is a sheet of thin metal that has net-like patterns or a wire mesh. Wire gauze is placed on the support ring that is attached to the retort stand between the Bunsen burner and the glassware to support the beakers, flasks, or other glassware during heating.
A tall narrow container with volume scale used especially for measuring liquids.
A lipped cylindrical glass container for laboratory use.
A round usually flat-bottomed laboratory vessel with a long neck.
A shallow, circular, transparent dish with a flat lid, used for the culture of microorganisms.
A short glass tube with a rubber bulb at one end and a tiny hole at the other, for measuring out drops of medicine or other liquids.
An optical instrument used for viewing very small objects, such as mineral samples or animal or plant cells, typically magnified several hundred times.
An instrument with two movable arms that are joined at one end, used for picking up and holding things.
A small, thin piece of glass used to cover and protect a specimen on a microscope slide.
A lens that produces an enlarged image, typically set in a frame with a handle and used to examine small or finely detailed things such as fingerprints, stamps, and fine print.
A metal stand consisting of a long upright rod attached to a heavy rectangular base that is used with rings and clamps for supporting laboratory apparatus.
 They are usually made of solid glass, about the thickness and slightly longer than a drinking straw, with rounded ends.
Or a rubber bung is mainly used in chemical laboratory in combination with flasks and test tube and also for fermentation in winery.
 A typical glass slide usually measures 25 mm wide by 75 mm, or 1 inch by 3 inches long, and is designed to fit under the stage clips on a microscope stage.


August 10th, 2016 - DigitalCrafts, Atlanta Tech Village
A blockchain is a public database with a record of numbers that individuals can transfer with transactions. These transactions are collected into blocks and timestamped. Each block is uniquely identified and will reference the previous block. To prevent there being two competing block chains, computational effort must be used for a block to become valid. This roughly averages the time between blocks to be around ten minutes.
Is a mathematical means to be able to verify that someone has knowledge of a secret large number without it being necessary to share the number.
You can think of the bitcoin blockchain as a database.
In bitcoin, a transaction can move bitcoin from one address to another by defining how a transaction can be modified.
A transaction has inputs and outputs.
The outputs describe the new "locks" where the inputs unlock previous outputs. An input will reference an previous output and provide an additional unlocking script.
Bitcoin uses a domain specific, stack based language to construct "locks", called script. The input script plus the output script are combined and executed. If the end value is true then the bitcoin is unlocked, and the value can move to a new output.
OP_TRUE
Anyone can spend
OP_RETURN
The output is provably unspendable
65 0x0496b538e853519c... OP_CHECKSIG
Pay to public key (historical)
OP_DUP OP_HASH160 20 0xa09be8040cbf399926aeb1f470c37d1341f3b465 OP_EQUALVERIFY OP_CHECKSIG
Pay to public key hash
OP_2 33 0x02987fe2... 33 0x033049a... OP_2 OP_CHECKMULTISIG
Pay to multiple public keys (bare multisig)
OP_HASH160 20 0xebb275803c6eb384e89ec52f654ea610883425c9 OP_EQUAL
Pay to script hash (multisig)
There are two main supported networks for Bitcoin.
Setup project and load dependencies
mkdir bitcore-workshop
cd bitcore-workshop
npm init
npm install bitcore-lib qrcode-terminal --save
node
Generate a private key and address
var bitcore = require('bitcore-lib');
var qrcode = require('qrcode-terminal');
var privateKey = new bitcore.PrivateKey('testnet');
var address = privateKey.toAddress();
qrcode.generate('bitcoin:' + privateKey.toAddress());
console.log(address);
View transaction history and the unspent output
https://test-insight.bitpay.com/address/ADDRESSHERE
https://test-insight.bitpay.com/api/addr/ADDRESSHERE/utxo
Generate a transaction
var tx = bitcore.Transaction();
tx.from(UTXOHERE); // adds input to transaction
tx.to(ADDRESSHERE, 900000); // adds output to transaction
tx.change(YOURADDRESS); // adds output with remainder amount
tx.addData('my name', 'ascii'); // adds output with data
tx.sign(privateKey); // adds scripts to inputs
tx.serialize(); // serializes as a hex string
Broadcast transaction
https://test-insight.bitpay.com/tx/send
If you would like to run your own block explorer API instead of using https://test-insight.bitpay.com
, you can run these two commands and wait (several hours to a day).
$ npm install -g bitcore
$ bitcored
For more details: https://bitcore.io/guides/full-node
The unique attribute to look for when searching for a hosted provider is an ability to scale the disk usage independently from CPU and memory usage. A few ideas:
You can also take a look at https://bitnodes.21.co/nodes/?q=bitcore for ideas.
This market could use some improvement.


All images and text © Mary Benton, 2021.
This site developed by Duncan Colhoun, Graduate of Cohort34, Central New Mexico Community College Deep Dive Coding.


Programming actors
[Functionality by programming task]
Collaboration diagram for Programming actors:
Modules | |
| Programming integer actors | |
| Programming set actors | |
| Reified propagator patterns | |
| Generic branching based on view and value selection | |
| Propagator patterns | |
| Patterns for set propagators | |
Classes | |
| class | Gecode::ViewArray< View > |
| View arrays. More... | |
| class | Gecode::Actor |
| Base-class for both propagators and branchings. More... | |
| class | Gecode::Propagator |
| Base-class for propagators. More... | |
| class | Gecode::BranchingDesc |
| Branch description for batch recomputation. More... | |
| class | Gecode::Branching |
| Base-class for branchings. More... | |
Partial fixpoints | |
| ExecStatus | Gecode::Propagator::ES_FIX_PARTIAL (PropModEvent pme) |
| Propagator has computed partial fixpoint | |
| ExecStatus | Gecode::Propagator::ES_NOFIX_PARTIAL (PropModEvent pme) |
| Propagator has not computed partial fixpoint | |
Defines | |
| #define | GECODE_ME_CHECK(me) |
| Check whether modification event me is failed, and forward failure. | |
| #define | GECODE_ME_CHECK_MODIFIED(modified, me) |
| Check whether me is failed or modified, and forward failure. | |
| #define | GECODE_ME_FAIL(home, me) |
| Check whether modification event me is failed, and fail space home. | |
| #define | GECODE_ES_CHECK(es) |
| Check whether execution status es is failed, and forward failure. | |
| #define | GECODE_ES_FAIL(home, es) |
| Check whether execution status es is failed, and fail space home. | |
Typedefs | |
| typedef int | Gecode::PropModEvent |
| Propagator modification events. | |
Enumerations | |
| enum | Gecode::ExecStatus { Gecode::ES_FAILED = -1, Gecode::ES_NOFIX = 0, Gecode::ES_OK = 0, Gecode::ES_FIX = 1, Gecode::ES_SUBSUMED = 2, Gecode::__ES_FIX_PARTIAL = 3, Gecode::__ES_NOFIX_PARTIAL = 4 } |
| Status of constraint propagation and branching commit. More... | |
| enum | Gecode::PropCost { Gecode::PC_CRAZY_LO = 0, Gecode::PC_CRAZY_HI = 0, Gecode::PC_CUBIC_LO = 1, Gecode::PC_CUBIC_HI = 1, Gecode::PC_QUADRATIC_LO = 2, Gecode::PC_QUADRATIC_HI = 2, Gecode::PC_LINEAR_HI = 3, Gecode::PC_LINEAR_LO = 4, Gecode::PC_TERNARY_HI = 5, Gecode::PC_BINARY_HI = 6, Gecode::PC_TERNARY_LO = 6, Gecode::PC_BINARY_LO = 7, Gecode::PC_UNARY_LO = 7, Gecode::PC_UNARY_HI = 7, Gecode::PC_MAX = 7 } |
| Classification of propagation cost. More... | |
Functions | |
| void | Gecode::Space::fail (void) |
| Fail space. | |
| bool | Gecode::Space::failed (void) const |
| Check whether space is failed. | |
| bool | Gecode::me_failed (ModEvent me) |
| Check whether modification event me is failed. | |
| bool | Gecode::me_modified (ModEvent me) |
| Check whether modification event me describes variable modification. | |
| PropCost | Gecode::cost_lo (int n, PropCost pc) |
| Dynamic low-propagation cost computation. | |
| PropCost | Gecode::cost_hi (int n, PropCost pc) |
| Dynamic high-propagation cost computation. |
Define Documentation
|
|
Value: if (::Gecode::me_failed(me)) \ return ::Gecode::ES_FAILED; To be used inside the propagate member function of a propagator or the commit member function of a branching. Definition at line 29 of file macros.icc. |
|
|
Value: { \ ModEvent __me__ ## __LINE__ = (me); \ if (::Gecode::me_failed(__me__ ## __LINE__)) \ return ::Gecode::ES_FAILED; \ modified |= ::Gecode::me_modified(__me__ ## __LINE__); \ } To be used inside the propagate member function of a propagator or the commit member function of a branching. Definition at line 40 of file macros.icc. |
|
|
Value: if (::Gecode::me_failed(me)) { \ (home)->fail(); \ return; \ } To be used inside post functions. Definition at line 53 of file macros.icc. |
|
|
Value: if ((es) < ::Gecode::ES_OK) \ return ::Gecode::ES_FAILED;
Definition at line 65 of file macros.icc. |
|
|
Value: if ((es) < ::Gecode::ES_OK) { \ (home)->fail(); \ return; \ }
Definition at line 73 of file macros.icc. |
Typedef Documentation
|
|
Propagator modification events. Propagator modification events are used by propagators. A propagator stores a modification event for each variable type. They can be accessed through a variable or a view from a given propagator. They can be constructed from a given modevent by a variable or view. |
Enumeration Type Documentation
|
|
Status of constraint propagation and branching commit.
|
|
Function Documentation
|
|
Propagator has computed partial fixpoint Set propagator modification events after processing of variables to pme.
|
|
|
Propagator has not computed partial fixpoint Set propagator modification events before processing of variables to pme.
|
|
|
Fail space. This is useful for failing outside of actors. Never use inside a propagate or commit member function. The system will crash! |
|
|
Check whether space is failed. Note that this does not perform propagation. This is useful for posting actors: only if a space is not yet failed, new actors are allowed to be created. |
|
|
Check whether modification event me is failed.
Definition at line 42 of file modevent.icc. |
|
|
Check whether modification event me describes variable modification.
Definition at line 47 of file modevent.icc. |
|
|
Dynamic low-propagation cost computation. If n is less than 4, use constant low-costs, otherwise use pc. Definition at line 268 of file propagator.icc. |
|
|
Dynamic high-propagation cost computation. If n is less than 4, use constant hight-costs, otherwise use pc. Definition at line 275 of file propagator.icc. |


Custom Sound System
-
Description
I am wanting to wire a surround sound system in my dorm room so I can host movie nights and other various activities for my floor. -
What I Need
- 12 gauge wire
- Soldering iron
- Solder
- RCA cables
-
Why I Need It
I'm wanting to use this equipment to not only host events in my room, but to gain some experience in electrical work. The wire and RCA cables will be used to connect speakers positioned at various locations. The solering iron and solder will be used to connect the wires. -
Location


WITNESS LIST Health & Human Services Committee March 15, 2005 - 9:00A SB 248 ON: Lenarduzzi, Roland Veterinarian (Texas Veterinary Medical Association), Manvel, TX Registering, but not testifying: For: Crocker, Maureen Deputy Director of Governmental Affairs (City of Houston), Houston, TX Holloway, Cile Volunteer (Self), Frisco, TX Hubbard, John Lobbyist (Texas Federation of Humane Socities), Austin, TX Johnson, Howard Animal Shelter Veterinarian (Self), Dripping Springs, TX Moore, Leila Director of Humane Societies (Bastrop County Humane Society), Bastrop, TX Nordyke, Patricia Executive Director (Texas Federation of Humane Societies), Manchaca, TX Trimble, Skip Real Estate Executive (Metroplex Animal Coalition), Dallas, TX SB 271 FOR: Davis, Howard Draftsman (Self), Rockwall, TX Davis, Kristi Insurance (Self), Rockwall, TX Turner, Amanda Aerospace (Self), Mesquite, TX ON: Lewis, Candice Student (Austin Civil Liberties Union), Austin, TX Registering, but not testifying: For: Cleveland, Tanja Paralegal Student (Self), Rowlett, TX Nevels, Carolyn Childcare Provider (Self), Fort Worth, TX Nevels, John Transportation Administrator (Self), Fort Worth, TX On: Connelly, Marc Allen Assistant General Counsel (Department of State Health Services), Austin, TX Harris, Geraldine State Registrar (Department of State Health Services), Austin, TX Providing written testimony: For: Edwards, Brenda Homemaker (The MISS Foundation and her grandson), Weatherford, TX Ellis, Rebekah Accountant (Self), Mesquite, TX SB 423 ON: Garanflo, Jaime Director of Customer Affairs (Texas State Board of Medical Examiners), Austin, TX Whitten, Meredith Policy Analyst (Sunset Commission), Austin, TX SB 424 ON: Garanflo, Jaime Director of Customer Affairs (Texas State Board of Medical Examiners), Austin, TX Registering, but not testifying: For: Kroll, Carrie Director of Advocacy (Texas Pediatric Society), Austin, TX SB 521 FOR: Baumgardner, David Ambulance Service Director (Texas Ambulance Association), Texarkana, TX Sprinkle, G.K. Public Policy Consultant (Texas Ambulance Association), Austin, TX Registering, but not testifying: On: Bavousett, Terry State EMS Director (Department of State Health Services), Austin, TX SB 523 FOR: Jurenka, Jerry Anne Volunteer (Texas Affiliate - American Heart Association), Austin, TX Rodriguez, Ernesto Paramedic and Administrator (American Heart Association), Austin, TX ON: Bavousett, Terry State EMS Director (Department of State Health Services), Austin, TX Shelton, Steve Executive Director (East Texas Area Health Education Center/University of Texas Medical Branch), Galveston, TX Registering, but not testifying: For: Welsh, Dinah Director of State Affairs (Texas Hospital Association), Austin, TX SB 563 ON: Winter, Raymond Assistant Attorney General (Office of the Attorney General), Austin, TX SB 626 FOR: Kafka, Bob Organizer (ADAPT), Austin, TX McCarthy, Amber Public Policy (National Multiple Sclerosis Society), Austin, TX Mizcles, Amy Director of Governmental Affairs (The Arc of Texas), Austin, TX Murphree, Susan Disability Policy Specialist (Advocacy, Inc.), Austin, TX Registering, but not testifying: For: Cranston, Ron Volunteer Disability Rights Advocate (ADAPT), Austin, TX Crowe, Michael Attorney/Lobbyist (Texas Assisted Living Association), Austin, TX Langendorf, Jean Executive Director (United Cerebral Palsy of Texas), Austin, TX McPhail, Jennifer (ADAPT), Austin, TX Park, Jodi Director of Projects and Communications (Coalition of Texans with Disabilities), Austin, TX Stalvey, Beth Public Policy Director (Texas Council for Developmental Disability), Austin, TX Thomas, Stephanie Disability Organizer (Institute for Disability Access), Austin, TX On: Horn, Adelaide Deputy Commissioner (Department of Aging and Disability Services), Austin, TX Tucker, Elizabeth (Texas Community Integration Collaborative), Austin, TX Providing written testimony: For: Meinkowsky, John Policy Advocate (ARCIL, INC.), Austin, TX SB 627 FOR: Horton, Colleen Public Policy Director (Texas Center for Disability Studies, UT), Austin, TX Mizcles, Amy Director of Governmental Affairs (The ARC of Texas), Austin, TX Murphree, Susan Disability Policy Specialist (Advocacy, Inc.), Austin, TX Park, Jodi Director of Projects & Communications (Coalition of Texans with Disabilities), Austin, TX Saenz, Danny (Self), Austin, TX Tucker, Elizabeth Disability Services (Texas Community Integration Collaborative), Austin, TX AGAINST: Brito, Allison Manager (EduCare Community Living), Austin, TX Butler, Lora Administrator (Mission Road Developmental Center), San Antonio, TX Henning, Peter Administrator of HCS & ICF (Bethesda Lutheran Homes and Services, Inc.), Cypress, TX Hernandez, Richard Director of Governmental Affairs (EduCare Community Living), Austin, TX Lautner Smith, Annette Executive Director (EduCare - Esperanza), Austin, TX Palombi, Therese Associate Director (Private Providers Association of Texas), Austin, TX ON: Horn, Adelaide Deputy Commissioner (Department of Aging and Disability Services), Austin, TX Walker, Lisa Medical Director for Children with Special Healthcare Needs (Department of State Health Services), Austin, TX Registering, but not testifying: For: Brown, William Retired, Volunteer (AARP), Austin, TX Cranston, Ron Volunteer (ADAPT), Austin, TX Dennis, Hilary (Texas Medical Association), Austin, TX Kafka, Bob Organizer (ADAPT), Austin, TX Kroll, Carrie Director of Advocacy (Texas Pediatric Society), Austin, TX Langendorf, Jean Executive Director (United Cerebral Palsy of Texas), Austin, TX Lynch, Louise Director, Developmental Disabilities (Austin Travis County Mental Health Mental Retardation), Austin, TX McCarthy, Amber Public Policy (National Multiple Sclerosis Society), Austin, TX McPhail, Jennifer (ADAPT), Austin, TX Oldham, Melanie Physical Therapist (Self), Angleton, TX Sanchez, Joe State Director of AARP (Amercican Association of Retired Persons), San Antonio, TX Stalvey, Beth Public Policy Director (Texas Council for Developmental Disbalitities), Austin, TX Thomas, Stephanie Disability Organizer (Institute for Disability Access), Austin, TX Against: Gray, W.K. Residental Provider of Medical Services (Kenmar Residential Services), Round Rock, TX Grayson, Julia Healthcare (EduCare), Austin, TX Hullum, Joyce (EduCare), Austin, TX Steur, Jane Vice President (EduCare), Austin, TX Weatherson, Wendy Executive Director (EduCare/Rescare), Denton, TX Wright, Susan QMRP (EduCare/Rescare), Denton, TX Providing written testimony: For: Meinkowsky, John Policy Advocate (ARCIL, INC.), Austin, TX Against: Reding, Julie Manager (Educare Community Living), Austin, TX SB 632 FOR: Lane, Ronda President (Texas Dental Assistants Association), Irving, TX Long, Jerry Dentist (Texas Dental Association), Houstin, TX Mendoza, Celena Dental Assistant (Self), Austin, TX Peppard, Mark Dentist (Texas Dental Association), Austin, TX Tolar, Jeanette Dental Assistant (Self), Round Rock, TX Wade, Herb Pediatric Dentist (Texas Dental Association), Bryan, TX Wineinger, Joanne Dental Assistant (Texas Dental Assistants Association), Corinth, TX AGAINST: Henson, Niki Dental Assistant, Dental Assistant Educator (Cornerstone Dental Academy), Houston, TX ON: Sanders, Sherri Director of Licensing (State Board of Dental Examiners), Austin, TX Registering, but not testifying: For: Bingham, William Lawyer (Texas Dental Association), Austin, TX Jones, Theresa Ann Certified Dental Assistant (Self), Austin, TX Nordin, Erica Dental Assistant (Self), Austin, TX Rudd, Jim Lawyer/Lobbyist (TSOMS - Oral Surgeons), Austin, TX Schnabel, Charlie Consultant (Texas Academy of Pediatric Dentistry), Pflugerville, TX Williams, Liz Certified Dental Assistant (Self), Austin, TX On: Schmidt, Bobby Executive Director (Texas State Board of Dental Examiners), Austin, TX Providing written testimony: For: Rainosek, Ronald General Dentistry (Texas Academy of General Dentistry), Hanker Heights, TX


title = "Showcase | Primal Light"
url = "/showcase/primal-light"
layout = "showcase-item"
description = "Primal Light showcase page"
is_hidden = 0
==
{##}
{% put title %} Primal Light {% endput %}
{% put author %} Fat Gem {% endput %}
{% put author_url %} https://twitter.com/primallightgame {% endput %}
{% put release_date %} July 2020 {% endput %}
{% put platforms %} windows, macos, linux {% endput %}
{% put description %}
Primal Light is a linear 2D action platformer for Windows, Mac, and Linux.
Inhabit Krog, a mysterious blue creature in a red loincloth, as he traverses a
labyrinth of ladders, levers, traps, and monsters. Explore the nooks and
crannies of a bizarre and evocative world as you hack and slash your way to
victory, leaving a graveyard of grotesque bosses in your wake.
Features
- Explore a bizarre and evocative world filled with ladders, levers, traps, and monsters, arranged linearly across 10 levels.
- Face 10 challenging bosses in arcade-style combat reminiscent of the 16-bit era.
- Master new acrobatic abilities as you progress, allowing you to overcome obstacles and enemies.
- Dive into challenging side paths to uncover hidden collectibles, unlocking upgrades and passive abilities.
- Experience jaw-dropping pixel art and a hypnotic soundtrack.
{% endput %}
{% put image %} primal-light.png {% endput image %}
{% put placeholder %} linear-gradient(90deg, #24190a 5%, #24190a 15%, #25190a 28%, #25190a 83%) {% endput %}
{% put youtube_embed_code %} Kf4lVuTYdeM {% endput %}
{% put link_steam %} https://store.steampowered.com/app/771420/Primal_Light/ {% endput %}


This page demonstrates the timeline zoom and move functions
Zoom controls
Move controls
Icons by
DryIcons
and
TpdkDesign.net


Peeking into the JVM
1 Introduction
- Some details inside the JVM
- How the JVM fits into the bigger picture
- It's a big subject, we won't get to all of it
- Why I think the JVM is cool
2 What is the JVM
- Part of the Java Platform
- Java is a tool for producing software in a platform independant way
- Compile code once, run it anywhere (in theory)
- Sandboxing
3 Native code
In order to run code it has to be converted to a set of instructions that the CPU on that machine understands.
So the traditional process for developing software is to compile the source code into the instruction set that a specific computer architecture understands.
And then in order to run it on another architecture, it needs to be recompiled first, and any architecture specific portions (such as the GUI etc) may need to be 'ported' or rewritten to work on the new platform.
If you want to run the software on a platform to which it hasn't been ported, you are out of luck (other than porting it yourself of course).
4 Java model
The JVM follows a different model. Instead of compiling the code to native instructions for each platform, it is compiled once to a generic "bytecode".
bytecode is a very simple instruction set and it is designed to be executed very fast by the CPUs. It consists of simple instructions that move data onto and off a stack, simple arithmetic etc.
This is still a compilation, because the bytecode designed to be much simpler and quicker to execute.
Of course you still can't run this bytecode on the machine, because the CPU doesn't understand those instructions. So you need an 'interpreter', which is a piece of software that will interpret and execute this bytecode.
This means that the software developer can create and compile their software once and it will run identically (in theory) on any platform that has a Java bytecode interepreter available. This is the Java Virtual Machine, or JVM.
So it is decoupling the software creation process from the execution platform. To support a new platform, you port the JVM and all of the existing software will start working on it without having to be recompiled.
It's worth pointing out here that this isn't quite the whole picture: as we said earlier the Java bytecode is a very simple, low-level architecture suitable for abstracting computation. But there is still a higher level at which the platforms differ, so for example, the process of locating and opening a file will be potentially very different on a Windows machine compared to say a Linux one.
So the Java Runtime Environment, as well the JVM, also includes a
massive and extremely comprehensive standard library that Java
software can rely on to provide an, again entirely platform
independant abstraction over these details, allowing us to just
option, for example a FileInputStream
and not have to worry about
how that is actually implemented on each platform.
4.1 Standard library
- A much higher-level of abstraction
- On each platform, it knows how to, e.g
- open a network socket
- load classes
- find a file by name
- etc.
- Provides higher-level data structures and utilities
- List
- InputStream
- Encryption
- etc.
- Adds new features all the time, e.g. Java8 → Java9 etc
4.2 The Java Specification
5 What's in the JVM?
5.1 Heap
- Memory where objects etc are allocated
- Global in the VM instance (i.e. shared across threads)
- Allocated data remains until de-allocated
- Garbage collected to automatically de-allocated unused items
5.2 Methods
- The stage space where executable bytecode loaded from class files is stored.
5.3 Threads
- An individual execution state
5.4 Stacks
- Ephemeral storage
- Local variables
- Unique to a thread
5.4.1 Call stack
5.4.2 Call stack - visit
5.4.3 Call stack - return
5.4.4 Stacktrace
public class Excep { public static void fn2() throws IllegalArgumentException { throw new IllegalArgumentException(); } public static void fn1() throws IllegalArgumentException { fn2(); } public static void main(String[] args) throws IllegalArgumentException { fn1(); } }
Exception in thread "main" java.lang.IllegalArgumentException at Excep.fn2(Excep.java:3) at Excep.fn1(Excep.java:7) at Excep.main(Excep.java:11)
6 What does bytecode look like?
- 1-byte opcode specifying operation to be performed
- Followed by zero or more operands
- the specific bytecode defines how many of what type of operands it takes
- Very little typing
- the compiler still has to do that work before generating the bytecode.
- primitive types, int, long etc.
reference
type
6.1 yeah but I want to see it
- We can use
javap
to disassemble class files and take a look.-c
to include 'disassembly' to byte code-verbose
to include the constant pool
6.2 A simple example - Java source
Java code:
public void count(int max) { int i = 0; while(i < max) i++; }
6.3 A simple example - bytecode
6.4 A simple example - bytecode 2
6.5 A simple example - bytecode 3
6.6 A simple example - bytecode 4
6.7 A simple example - bytecode 5
6.8 A simple example - bytecode 6
7 The Class file
- Bytecode is stored in a Class file (e.g. on disk etc)
- Each class file contains the definition of a single class, interface, or module
- Used at compile time as well as run-time
7.1 Class file format
- A stream of platform-agnostic bytes
- e.g. always big-endian etc.
- Usually stored on disk but really it is anything created by a class loader
- could come from network
- or even be generated dynamically
Slightly glossing over some of the details, the way the JVM loads an application is by identifying the classes that it needs to run, searching the Classpath for some on-disk (or on-network) representation of these classes, and then it loads them in memory and instantiates them as neccessary. Classes as the JVM sees them have many of the properties that exist at the higher-level of the languages used to create those classes, such as methods with associated visibility, and properties etc.
The fact that the JVM understands Classes and methods and so on is an indicator that it does exist at a higher-level than native machine-code, so the JVM does need to do a fair bit more work than just loading code into memory and executing it.
7.2 Header
- Magic Constant that identifies the beginning of the stream as a Class File
- Version number
$ hexdump -C Count.class 00000000 ca fe ba be 00 00 00 38 ...
7.3 Constant pool
- Avoids having to repeat constants over and over again
- Constants are just appear as an index into this table
0: ldc #2 // String Hello World 2: astore_1
7.4 Method definitions
The core instructions which define the computations.
8 Optimisations
- The spec just defines the external view of the behaviour
- Lots of scope to improve the way the JVM performs without changing it's behaviour at the abstract level
8.1 Just-In-Time compilation
- Code actually gets faster the more it runs
8.1.1 Compile to native code
- The JVM is capable of compiling to native code on the fly
- But compiling takes time
- If a piece of code only runs once, for less time than it takes to compile it, you don't save time
8.1.2 Compile only when needed
- The JVM detects 'hot' code
- code which is executed many times
- and compiles it after a certain threshold
9 Garbage Collector
- Tracks references to objects
- Frees the memory when they are no longer referenced / reachable
- Removes the burden on the programmer to manage memory
9.1 Marking phase
- searches all objects to see which are accessible
- marks objects as used or unused
- can take a very long time if all objects need to be searched
9.2 Deletion phase
- frees up space by deleting objects marked as unused
- results in fragmented free space
- which can affect performance
9.3 Compaction phase
- moves objects around to make contiguous free space
- requires freezing the VM so it can move objects around
9.4 Optimisations
- Generational collector
- most objects are short lived
- limit 'minor' collections to just young objects
- quicker because it searches fewer objects
- Concurrent sweep
- don't stop the world
- cannot compact memory
- etc…!
10 Graal
10.1 A new(ish) JVM
- Written in Java
- Provides compilers and runtimes for many non-Java languages
- Javascript, Ruby etc
- Ahead-of-time compiler:
- compiles bytecode to native
- Still follows the same concepts as those outlined here
- just a better implementation of them
11 References & more info
- Crafting Virtual Interpreters - "A handbook for making programming languages."
- Invoke Dynamic - from article "Java Virtual Machine Support for Non-Java Languages"
- Java VM Specification
- Java Garbage Collection Basics
- Top Ten Things to do with GraalVM


Alignment of MusicBrainz and Doremus entities
Latest MB database update: 2021-01-13
Latest update: 2021-02-01
Count links in either direction between MusicBrainz and Doremus
from_mb
from_doremus
area
0
0
artist
0
3727
event
0
0
instrument
0
0
label
0
0
place
0
0
recording
0
0
release
0
0
release_group
0
0
series
0
0
work
0
0


Contents
Server-Side Resource Access API
Server-Side Computation API
Server-Side Communication API
Server-Side Resource Access API
Server-Side Computation API


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| DOSE: |
|
smoked |
DMT |
(powder / crystals) |
I first tried this years ago, and misfired because the smoke was too harsh. The following is a very ineadequate accounting of my second attempt--and first experience--with DMT.
I had done a great deal of LSD and mushrooms, and considered myself experienced in terms of psychedelia. Having taken over ten grams of mushrooms more than once I felt that I could always remind myself that I, as the observer, had made a choice.

My partner, and so called trip guide, was an intelligent man in his fifties (I was thirty), and had also introduced me to peyote. We had agreed that the experience would occur at his place, and all of the usual pre-trip steps were taken...i.e., the fasting, the meditation, and so on.
At this point I must interject that my meditations were, up to the experience, a facade, although I was not yet aware of this fact. I simply thought about myself. Real hard. Even some of the more difficult mushroom experiences that I had undergone up until then had not purged me of my buried feelings of inadequacy, and this is important to mention here, because I did not understand something very VERY crucial, and that is that I was not trying DMT to learn, but rather, to PROVE something to myself. This is very unwise.
The crystals were smoked from a pipe, and among a few tobacco grounds. I was able to draw a good amount from the end of the pipe, and yet again, and I tried to hold the smoke but again, I could not. I exhaled, halfway expecting that I would get the so-called 'museum dose' of the compound.
I have read much literature about DMT. I cannot say that anything has come close to adequately describing even the most miniscule element of the experience. I did not notice anything at all in terms of distortions before my mind went.
The feeling is very difficult to relate with words. Imagine understanding your own mind to be a map, a very small representation of a very large idea, and suddenly discovering that it was, in fact, foldable, and that it had been folded for all time.
I sensed my mind was flat, and very inadequate, and that I had been folded up and put away, so to speak, centuries ago, forever ago, because I was discarded. I was effluent. I was a remnant of a grand theme, once possible, but now ruined and shattered, and as a conscious entity I could not be destroyed, but only amused. The amusement ended when the occlusion to its purpose ended, and I became aware of my SOLITUDE. This was immediate and powerful.
I cannot recall the transition to the void, there were no colors, or visions in the traditional sense. I realized immediately that I had actually poisoned myself, and this was not a DMT trip at all, this was death.
This period of time is impossible to relate. Try to understand that there was no sensation of time at all. Nothing was linear, and my ideas seemed to come to me at impossible intervals. My brain had been killed, I could tell, because I could not think. I could only sense the overwhelming loneliness and shame. I had actually believed at some point, somewhere, that I was alive, but this was not possible, because I was a scrap of discarded thought, not worthy of keeping. It was a foregone conclusion that I would destroy myself.
This seemed to be forever.
There appeared in the vastness a tiny point of light. I remember realizing that I had not died at all, but that I had been dead. Then, not dead, but dormant. DORMANT. I was about to be born.
The feeling of flying is not an accurate description of the sensation that accompanied my movement toward the point, which was gold, and, to my surprise, was actually metallic. I came immediately upon the source, which was a DNA scarab, a construct, an insect of impossible dimensions, miles in diameter and circumference.
The skin of the carapace was polished to a high sheen and thin to the point of transparency. I could see tiny, endless arrangements of gears and pinions just beneath the gold wing, tiny points of alien light darted from what were molecular points of cognitive energy, impossible in color and detail, billions and billions of precision gears meshing quietly and generating consciousness, which was traversing a planned route, terrifying in its complexity, but beautiful in its exactitude.
I followed a point, there was warmth, to the top of the scarab's enormous body. It had a tiny human head, the size of a marble, attached via a series of DNA strands that had been transformed into a clear metal. The head was unaware of my presence and it had a small mouth, which opened to speak.
From the mouth came forth the matured beam of thought, which had started from a cog (Cognitive) in the belly of the insect, years ago, and had grown as it rose to the head, morphing into a form of concentrated phosphene light. the beam poured from the tiny mouth, and became stacatto at once, and conical, in sections that grew, as ideas, and hypnotized me into allowing myself to be enveloped by a punctuated green, now a geometry of raw cognition without ego, and with a destination.
I rode in the singular idea, aware of its purity and clarity, and above all, its sense of purpose, as it was not aware of my presence, and fell to a violet montage of heads which were dislocated and ethereal, but awaiting its arrival.
I was, suddenly, inside of a brain. I became instantly aware of the physicality of the idea, which was A NOTE OF MUSIC.
It was then revealed to me on a large screen, attached to a gleaming wall, that the brain was the brain of Bach, and the idea was one in a stream of many, and fell to his shaking hand in a dimly lit room, flickering with candlelight and heavy curtains, to the end of the point of his pen, where it was transcribed, in ink, and solidified forever.
This, I realized, happened concurrently with the HEARING of that exact note, in that exact piece of music, namely, the second of Six Motets, and that I had, in some elusive past, cued that CD to play while I tripped, and I was now revisiting that precise moment, which occured exactly then, and only then, and required of the universe the creation of cognition and the receiving thereof, just to hear the one note, exactly there, in exactly that fashion.
I watched the transcription through a telescope from a starship, and realized that it was diminished only by my yearning to beccome a stenographer of music (I am a musician). My own music seemed like noise.
I saw the fatigue in the wrinkled forhead of the great master, Johann Sebastian Bach, as he received the beams of knowledge, and his music was living.
From there I was told by a small man sitting in a plant that I was mediocre, and that in and of itself, my mediocrity had a function, which was to define what is great, and what is not, because how can the great be great if it is commonplace?
I, in my mediocrity, was a necessary element of greatness, then, and this eased my spirit.
I found myself at that point laying on a couch, and had a fleeting sensation of having taken a drug, and I realized that my heart was not beating, and that I was trying to enter my own body. I saw clearly the fear in my own eyes, and was saddened by my weakness.
I became preoccupied with my lying. Everything I was, was lies.  Even lying down, I was lying, always lying. My existence was a tangled cluster of lies, cancelling themselves out, struggling to make sense, surviving only on the energy that others gave when they turned to see the freak who could not tell the truth. And so I had lied to myself about DMT, and it was not a hallucinogen, it was a poison, used by all liars, to destroy themselves.  They were giant, glistening centipedes, hideously related in a mutant way to the glorious insects of cognition, but bastardized and diminished. I saw broken gears in their grotesque bodies, and they came from my own mouth while I lay there, motionless.
I then realized that they were being driven from me. I was undergoing a type of exorcism, and I was immediately aware of a ram on a hill of purple grasses, beyond a rushing stream of beautiful microscopic geometries. The ram had eyes all over its head, and beside was a horse that was ten feet tall at the shoulder, and breathing heavily. The horse watched, and then ran towards a greying horizon, while overhead a silver sun was spinning sounlessly.
The ram had driven the lies from me, and I approached the stream. There were machines in the stream, and I was told not to touch the water, but to find the crossing, and I realized that the cross of Christ was not a cross, but a crossing, from judgement into salvation, and that the stories of religion were allegories, froming themselves again and again until they could be superimposed over the framework of machinery that was my own personal syntax.
I realized the glory, the importance, of TRUTH.
The truth was that my fear ruled my existence.
Could salvation be truth?

It is impossible to adequately relate to those reading this that all of the above was occurring simultaneously, and yet, in right angles, and even moreover, in a corner of what I was to discover was a pile of powder on a floor, into which my eyeballs fell, and the dust did adhere.
I got up, yet I did not move.
My arm was hanging of the side of the couch, I remember, and there was my friend, watching a ball of regurgitated and spoiled silliness (television?), and he was unaware of my fear and astonishment, but turned his head to look at me.
His head was flat, and it scrolled as it turned, because there was no depth, and he himself was devoid of depth, and there was a pool of idea between I an he, and in the pool, an unfathomable depth, and in that depth, a monster.
How do I tell someone, anyone, that nothing so far related amounts to even one iota of the simultaneous aspect of dimensional revelation, and the absence of spacetime, and the simplicity of observation in the only-then-and-thereness of that particular embodiment of who I was and who I have become?
The experience cannot be shared, and as I read over what I have typed, I understand that I have only served to diminish the experience, and turn it into an absurdly inadequate written version of a cinematic version of a non-cinematic event.
What do I say from here?
Writing this seems like a wisp of a tentacle that remains, and seems like punishment, because it involves the re-integration of an ego so shattered, and yet necessary for day to day function, and I am acutely aware of my lies, insofar as I cannot tell what happened to any audience, no matter how hard I try.
There was, in the 'comedown', a moment of such beauty, when I became aware of the Motets, playing, still playing, perfectly and crisply, while I lay on the couch, being born.
A lot of people talk about the tragedy of one's life if their most profound experiences were those occurring under the influence of a drug.
Those people are unwatered seeds.
I have done DMT two other times. Each was more fantastic than the preceding. Indescribable, every second. I find that a part of me is convinced that this drug, this molecule, is of itself, alive, and was once married to us, and has since been divorced, and we are therefore in a state of bereavement and mourning.
And then I realize that we are longing, as humans, for contact, any contact, with ourselves and those whom we love, and that contact is so elusive, and seemingly inadequate, and yet, even every touch and word from another is a precious singularity, never to be repeated, but only diminished by retelling, and remembering, and finally, fading away.
I cannot communicate how my DMT experience altered everything forever. It was after this experience that I stopped all cocaine and crack, for good, never to visit them again. They are my enemy. I was taught this on, and by, DMT.
For those of you who are considering trying DMT, I would say, do not consider this to be even a shred of what to expect, there is NOTHING that can prepare you, there is no comparison to LSD, and while there may be some allegorical connection to the mushroom, the mushroom is like a movie of the actual life of DMT.
Anyway, I have talked incessantly to many people about the experiences I have had, and I wanted to share these aspects of this infinity here, if for no other reason, just to stimulate thought and curiosity.
DMT is bigger than me.
Experience Reports are the writings and opinions of the individual authors who submit them.
Some of the activities described are dangerous and/or illegal and none are recommended by Erowid.


WaterFern
Professor
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'Boys Don't Cry' (1999)
A movie review by Walter Frith
<EMAIL_ADDRESS>Member of the 'Online Film Critics Society' http://www.ofcs.org
The untimely death of Matthew Sheppard in Wyoming a few years ago made headlines around the world.  'Boys Don't Cry' focuses on the same subject matter and reverses genders in its story of friendship gone terribly wrong and is also based on a true story. It attempts to follow a similar path in the way it looks pursuant to the 1991 film 'My Own Private Idaho' which starred Keanu Reeves and River Phoenix. That film was about a male prostitute making his way around the country and finding whoever he could in order to make a living selling his body. While different from 'Boys Don't Cry' in its subject matter, it still looks and feels very similar.
Actress Hilary Swank is scooping up virtually every major award for her portrayal of Teena Brandon, a lonely ne'er-do-well that has had run ins with the law and is struggling sexually to find her identity. She tries to pass herself off as Brandon Teena, a man, and falls in love with someone that provides tragic consequences. The film did disappoint me somewhat by surrounding itself with American mid-western folks perceived as white trash. Some, of course, are but there is good and bad in everyone and the film has no positive characters in it, they are all deeply flawed individuals so this makes the challenge of telling the story an uphill battle by putting the audience in a very bleak story that will stay in their minds long after the curtain drops. The characters in the film smoke too much, drink too much (which includes giving beer to infants), dress typically trashy and act with little regard for self respect, let alone respect for anyone else. I suppose if the story is true, the right circumstances have to be re-created but it still left me saying "*blah*". The saving grace of this film is the acting.
Teena Brandon (Hilary Swank) is seen near the beginning of the film fleeing from rednecks that want to kill her after she comes on as a man to a young teenaged girl and has to hide with a friend who will protect her. She has a date in court but may not show up which could lead to a bench warrant issued for her arrest.
Teena Brandon now becomes Brandon Teena as she passes herself off as a man and makes friends with some equally ne'er-do-wells. There are Tom and John (Brandon Sexton III and Peter Sarsgaard) and the girl Teena falls in love with, Lana (Chloe Sevigny), who is the only person that truly understands Teena and her performance is a great supporting effort with good chemistry along side Hilary Swank and the two of them are Oscar bound. They (all the young, free-minded characters) joy ride without seat belts while drinking, the girls wear too much make-up and look like they have had one too many trips to the local donut shop and the mother of one of the girls shows exactly where this bad behaviour on the part of her daughter and her friends came from. The film is a series of emotions expressed by all members of the cast as Teena's masquerade begins to fall apart and many hateful and eventually harmful things happen to her.
The film is progressively honest and doesn't hold one false note in its portrayal of these people and sophomore director Kimberly Peirce (1994's 'The Last Good Breath') has found a raw and pinching nerve to rely on that grabs the audience by the collar and doesn't let them go. The film is bound to generate controversy. There is a rape scene that reminded me of 1988's 'The Accused' with Jodie Foster. That film had Foster being gang raped after teasing some men in a bar and some wondered if it was really necessary to show the actual rape scene rather than imagine what it would have been like for the victim. Sometimes what we don't see on the screen can actually be more powerful than what we do see if the actors can convey their emotions and act out the stories they are telling.
The audience I saw 'Boys Don't Cry' with sat stone faced through its running time. I saw it at an art house with few seats in the theatre, and with a crowd that obviously knows how to appreciate a small, honest and low budgeted film like this. Definitely not a mainstream motion picture, its conclusion will be discussed for years among knowledgeable movie fans who see the performances as a work of art and the work of true professionals. There is Oscar buzz being generated and the cast deserves one big Oscar as none of them do it alone. Uniquely satisfying!
OUT OF 5 > * * * 1/2
Visit FILM FOLLOW-UP by Walter Frith http://www.cgocable.net/~wfrith/movies.htm
* * * * * - a must see * * * * 1/2 - don't miss it * * * * - an excellent film * * * 1/2 - a marginal recommendation * * * - can't quite recommend it * * 1/2 - don't recommend it * * - avoid it * 1/2 - avoid it seriously * - avoid it AT ALL COSTS 1/2 - see it at your own risk zero - may be hazardous to your health
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Related links: index of all rec.arts.movies.reviews reviews


--- layout: one-column title: AppVeyor 2.0 Beta description: The all new AppVeyor CI Beta ---
After 4 months of intensive development we are excited to announce a public beta of AppVeyor 2.0! This new release provides you with whole new experience: build environment that is under your full control, large projects support with build matrix and parallel testing, scriptless deployment and release management!
You could see those great features in flagman continuous integration services for Linux such as Travis CI, but not for Windows up until now. Today, I'm really proud to say that AppVeyor is the only CI solution for Windows that offers dedicated build machines with admin access, build matrix with jobs parallelization and integrated deployment.
In AppVeyor 2.0 we are moving away from shared build servers to dedicated VMs. Every build job runs on pristine VM with admin rights! This was probably the main reason for kicking-off this release.
AppVeyor 2.0 has built-in hosting for private and public NuGet feeds.
Every account comes with a private password-protected NuGet feed aggregating packages from all projects and enabling publishing of your custom packages.
Projects have separate NuGet feeds with all NuGet packages pushed as artifacts.
Easily build/test for multiple configurations. Specify which operating systems, build configurations and platforms you would like to include into build matrix and AppVeyor will start a build with multiple jobs for all combinations.
Build matrix supports the following dimensions:
Large projects can contain hundreds and thousands of tests that could run for hours. AppVeyor 2.0 allows to split your tests into groups by categories, assemblies or custom criteria and run them as build jobs in parallel thus drastically reducing overall build time.
Read more about parallel testing
AppVeyor 2.0 has scriptless, repetitive one-click deployment to multiple environments! Deploy as part of the build or promote releases later - manually or through API.
Supported deployment providers: Web Deploy, FTP, Amazon S3, Azure blob, Azure Cloud Services, NuGet, Deployment Agent, Local (for integration testing) and Script.
Great Windows software must provide user interface for any function it has. AppVeyor 2.0 follows this tradition and further extends project settings, so you can control build environment and inject custom script logic on any stage of build pipeline without ever touching your repository!
For command-line gurus or those coming from Linux we added fancy YAML configuration support! Add appveyor.yml with project configuration into root of your repository and next time you fork the repo just add a new project in AppVeyor.
Read more about build configuration
AppVeyor 2.0 has completely re-designed UI to get results faster and on the go!
AngularJS, SignalrR and Foundation helped us to build great experience we're really proud of:
* Free plan with support of public repositories only. Let us know if you need private repositories support or want to play with parallel testing and we'll be happy to enable them for your account.
https://www.appveyor.com/docs/
Enjoy the beta and let us know if you have any questions or suggestions. We are looking forward to your feedback!


{% extends "layouts/_block_content.html" %} {% from "components/address-output/_macro.njk" import onsAddressOutput %} {% set page_title = "Contact us" %} {% block main %}
Opening hours:
Monday to Thursday 8:30am – 5pm
Friday 8:30am - 4:30pm


Changes will take place the next time you start your browser. Or if you don't want to close the browser you could uncheck and recheck the enabled box next to this extension on the Extensions tab page.


Zverev denies illegal phone use at ATP Finals
LONDON, Nov 14 — Alexander Zverev denied he was using his phone illegally during his ATP Finals round-robin defeat to Stefanos Tsitsipas at London’s O2 Arena.
The defending champion was asked about the incident during the post-match press conference following his 6-3, 6-2 defeat yesterday.
TV footage that circulated on social media appeared to show him touching something in his bag at a changeover during the match.
Rules state players cannot access any electronic devices during matches.
But Zverev, 22, insisted he did not have his phone with him on court.
“My phone was in the locker room,” he said. “I always leave it there. I don’t know what they saw, but it was definitely not a phone.”
When asked what he might have been touching in his bag, the German said: “I mean, a water bottle? Empty water bottle maybe?”
Zverev beat Rafael Nadal earlier in the week but his comprehensive defeat by Tsitsipas leaves his tournament hopes in the balance ahead of his final group match against Daniil Medvedev on Friday. — AFP


--- layout: default ---
During the summer of 2008, I rode my bike from San Francisco to Boston. It took me 54 days and I created a custom website and documented the journey online at Bikeacrossthe.us (I no longer own it)


Before Change
logger.exception(traceback.format_exc())
def handle_server_activity(self, data: dict, activity: Activity) -> None:
if activity.id in self.recently_delegated_events:
logger.info("ignoring event with id %s sine we delegated from this node" % activity.id)
return
logger.debug("got internally published event with verb %s id %s" % (activity.verb, activity.id))
if activity.verb in ["ban", "kick", "remove"]:
self.handle_local_node_events(data, activity)
else:
// otherwise it"s external events for possible analysis
environ.env.publish(data, external=True)
def kick(self, data: dict, activity: Activity, room_id: str, user_id: str, user_sid: str, namespace: str) -> None:
try:
_users = list()
if room_id in self.socketio.server.manager.rooms[namespace]:
After Change
logger.exception(traceback.format_exc())
def handle_server_activity(self, data: dict, activity: Activity) -> None:
try:
self.handle_server_activity(data, activity)
except Exception as e:
logger.error("could not handle server activity: %s" % str(e))
logger.exception(traceback.format_exc())
def _handle_server_activity(self, data: dict, activity: Activity) -> None:
if activity.id in self.recently_delegated_events:
logger.info("ignoring event with id %s sine we delegated from this node" % activity.id)
return


Updating game files...
- files
Hey there! Seems like we haven't met yet. My name's Kitty. Wut's yours?
KITTYDEX
DODGE TO SURVIVE!
TAP TO SPACE JUMP!
Y.O.L.O.
SCORE: 2342
BEST:NEW! 2342
RANK: KITTY


A stacked Line chart using the table reader with a right aligned key
|
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
Monday |
Tuesday |
Wednesday |
Thursday |
Friday |
| Richard |
4 |
8 |
5 |
7 |
3 |
5 |
1 |
3 |
8 |
4 |
| Ricky |
7 |
4 |
8 |
9 |
1 |
6 |
7 |
2 |
3 |
2 |
| Rachel |
6 |
7 |
8 |
5 |
2 |
4 |
6 |
7 |
6 |
3 |
| Ruth |
3 |
5 |
4 |
8 |
6 |
3 |
2 |
9 |
8 |
7 |
This goes in the documents header:

Put this where you want the chart to show up:

<canvas id="cvs" width="750" height="350">[No canvas support]</canvas>

Monday
Tuesday
Wednesday
Thursday
Friday
Monday
Tuesday
Wednesday
Thursday
Friday

Richard
4
8
5
7
3
5
1
3
8
4

Ricky
7
4
8
9
1
6
7
2
3
2

Rachel
6
7
8
5
2
4
6
7
6
3

This is the code that generates the chart - it should be placed AFTER the canvas tag(s):


pdfjam-slides6up(1) pdfjam-slides6up(1) NAME pdfjam-slides6up - put presentation slides onto 6-up pages SYNOPSIS pdfjam-slides6up [--pagenumbering SWITCH] [OPTION [OPTION] ...] [SRC [PAGESPEC] [SRC [PAGESPEC]] ...] DESCRIPTION pdfjam-slides6up converts PDF files whose pages are presentation slides (with 4:3 aspect ratio) into 6-up versions suitable for making a handout (for example). By default, the 6-up pages do not themselves have page numbers. To put page numbers on the output pages, use either '--pagenumbering true' or, for example, '--pagenumbering 3.0cm' to place the page numbers a bit lower on the page than the default position. The value of 'SWITCH' must be either 'true', 'false' or a dimension that can be used by LateX. (To be precise, it's the value of the 'footskip' dimension in LaTeX; by default, pdfjam-slides6up sets that as 2.7cm, which works pretty well in conjunction with both '--paper a4paper' and '--paper letterpaper'.) If no source PDF file ('SRC') is specified, input is from /dev/stdin. If 'PAGESPEC' is omitted, all pages are processed. Source files are processed sequentially into a single output unless the '--batch' option is used, in which case they are processed separately. pdfjam-slides6up is a simple wrapper for pdfjam, which provides a front end to many of the capabilities of the pdfpages package for pdflatex. A working installation of pdflatex, with the pdfpages package, is required. pdfjam-slides6up operates on one or more PDF files, and (either with the '--batch' option or with '--outfile DIR' where 'DIR' is a directory) the resulting files have the suffix '-6up' applied to their names by default. To change the suffix, use the '--suffix' option, for example pdfjam-slides6up --suffix '2x3' --batch myslides1.pdf mys‐ lides2.pdf will result in files named 'myslides1-2x3.pdf' and 'myslides2-2x3.pdf'. By default a narrow line frame is printed around every slide. This can be turned off if required by using the option '--frame false'. pdfjam-slides6up is part of the "PDFjam" package of tools, whose homepage is at http://www.warwick.ac.uk/go/pdfjam . SETUP See http://go.warwick.ac.uk/pdfjam . USAGE For the other available options and site/user defaults, see the output of pdfjam --help For further information and some examples see http://go.war‐ wick.ac.uk/pdfjam . LIMITATIONS AND BUGS pdfjam-slides6up does not work with encrypted PDF files, and does not preserve hyperlinks. Please report bugs! See the website at http://www.warwick.ac.uk/go/pdfjam . LICENSE PDFjam is distributed under the GNU public license. SEE ALSO pdfjam(1) pdfjam-slides3up(1) . AUTHOR pdfjam-slides6up is written and maintained by David Firth as part of the PDFjam package. 10 March 2010 pdfjam-slides6up(1)


What is the IntelliJ Platform?
The IntelliJ Platform is not a product in and of itself but provides a platform for building IDEs. It is used to power JetBrains products such as IntelliJ IDEA. It is also Open Source and can be used by third parties to build IDEs, such as Android Studio from Google.
The IntelliJ Platform provides all of the infrastructure that these IDEs need to provide rich language tooling support. It provides a component driven, cross-platform JVM based application host with a high-level user interface toolkit for creating tool windows, tree views and lists (supporting fast search) as well as popup menus and dialogs.
It also includes an image editor as well as a full text editor, and provides abstract implementations of syntax highlighting, code folding, code completion, and other rich text editing features.
Furthermore, it includes open APIs to build common IDE functionality, such as a project model and a build system. It also provides infrastructure for a very rich debugging experience, with language agnostic advanced breakpoint support, call stacks, watch windows, and expression evaluation.
But the IntelliJ Platform’s real power comes from the Program Structure Interface (PSI). This is a set of functionality that can be used to parse files and build rich syntactic and semantic models of the code, and to build indexes from this data. This powers a lot of functionality, from quick navigating to files, types and symbols, to the contents of code completion windows and find usages, code inspections and code rewriting, for quick fixes or refactorings, as well as many other features.
The IntelliJ Platform includes parsers and a PSI model for a number of languages, and its extensible nature means that it is possible to add support for other languages.
Plugins
Products built on the IntelliJ Platform are extensible applications, with the platform being responsible for the creation of components, and the injection of dependencies into classes. The IntelliJ Platform fully supports plugins, and JetBrains hosts a plugin repository that can be used to distribute plugins that support one or more of the products. It is also possible to host your own repositories, and distribute plugins separately.
Plugins can extend the platform in lots of ways, from adding a simple menu item to adding support for a complete language, build system and debugger. A lot of the existing functionality in the IntelliJ Platform is written as plugins that can be included or excluded depending on the needs of the end product. See the Quick Start Guide for more details.
The IntelliJ Platform is a JVM application, written mostly in Java and Kotlin. You should be experienced with these languages, large libraries written in them, their associated tooling, and large open source projects to write plugins for products based on the IntelliJ Platform. At this time, it’s not possible to extend the IntelliJ Platform in non-JVM languages.
Open Source
The IntelliJ Platform is Open Source, under the Apache license, and hosted on GitHub.
While this guide refers to the IntelliJ Platform as a separate entity, there is no “IntelliJ Platform” GitHub repo. Instead, the platform is considered to be an almost complete overlap with the IntelliJ IDEA Community Edition, which is a free and Open Source version of IntelliJ IDEA Ultimate (the GitHub repo linked above is the JetBrains/intellij-community repo).
The version of the IntelliJ Platform is defined by the version of the corresponding release of IntelliJ IDEA Community Edition.
For example, to build a plugin against IntelliJ IDEA (2019.1.1,) build #191.6707.61, means specifying the same build number tag to get the correct Intellij Platform files from the intellij-community
repo.
See the build number ranges page for more information about build numbers corresponding to version numbering.
Typically, an IDE that is based on the IntelliJ Platform will include the intellij-community
repo as a Git submodule and provide configuration to describe which plugins from the intellij-community
, and which custom plugins will make up the product. This is how the IDEA Ultimate team work, and they contribute code to both the custom plugins and the IntelliJ Platform itself.
IDEs Based on the IntelliJ Platform
The IntelliJ Platform underlies many JetBrains IDEs. IntelliJ IDEA Ultimate is a superset of the IntelliJ IDEA Community Edition, but includes closed source plugins (see this feature comparison). Similarly, other products such as WebStorm and DataGrip are based on the IntelliJ IDEA Community Edition, but with a different set of plugins included and excluding other default plugins. This allows plugins to target multiple products, as each product will include base functionality and a selection of plugins from the IntelliJ IDEA Community Edition repo.
The following IDEs are based on the IntelliJ Platform:
- JetBrains IDEs
- Android Studio IDE from Google.
- Comma IDE for Raku (formerly known as Perl 6)
- CUBA Studio
- Cursive IDE for Clojure
Rider
JetBrains Rider uses the IntelliJ Platform differently than other IntelliJ based IDEs. It uses the IntelliJ Platform to provide the user interface for a C# and .NET IDE, with the standard IntelliJ editors, tool windows, debugging experience and so on. It also integrates into the standard Find Usages and Search Everywhere UI, and makes use of code completion, syntax highlighting, and so on.
However, Rider doesn’t create a full PSI (syntactic and semantic) model for C# files. Instead, it reuses ReSharper to provide language functionality. All of the C# PSI model and all inspections and code rewriting, such as quick fixes and refactorings are run out of process, in a command line version of ReSharper. This means that creating a plugin for Rider involves two parts - a plugin that lives in the IntelliJ “front end” to show user interface, and a plugin that lives in the ReSharper “back end” to analyze and work with the C# PSI.
Fortunately, many plugins can simply work with the ReSharper backend - Rider takes care of displaying the results of inspections and code completion, and many plugins can be written that don’t require an IntelliJ UI component. More details can be found in the Product Specific section.


This module provides the class representing the requests to throttle.
Exception that occurs when a finished is tried to change some attributes to a finished throttled request
| Parameters: | msg (string) – the message |
|---|
This class represents a throttled request
| Parameters: |
|
|---|
Create a throttled request with the given prepared request
| Parameters: | request (requests.PreparedRequest) – the prepared request to throttle |
|---|
The flag that indicates if the request has been processed
| Getter: | Returns finished |
|---|---|
| Type: | boolean |
The response obtained by processing the request
| Getter: | Returns response |
||||
|---|---|---|---|---|---|
| Setter: | Sets the response received after the processing of the request |
||||
| Raise: |
|
||||
| Type: | requests.Response |
Return the exception that occurs by processing the request (blocking)
| Getter: | Returns exception |
||||
|---|---|---|---|---|---|
| Setter: | Sets the exception raised during the processing of the request |
||||
| Raise: |
|
||||
| Type: | Exception |
Return the response obtained by processing the request
If timeout is None it waits until a response has been obtained or an execption occurs. When a response has been obtained it is returned, if an exception occurs it is raised. If timeout is not None and no response still hasn’t been obtained after the expiration of timeout, then None is returned.
| Parameters: | timeout (float) – the timeout value in seconds (default: 0) |
|---|---|
| Returns: | response or None |
| Return type: | requests.Response |
Return the exception that occurs by processing the request
If timeout is None it waits until a response has been obtained or an execption occurs. If an exception occurs it is returned otherwise None is returned. If timeout is not None and no response still hasn’t been obtained None is returned.
| Parameters: | timeout (float) – the timeout value in seconds (default: 0) |
|---|---|
| Returns: | exception or None |
| Return type: | Exception |


ARCTIC WILD
SCHEDULE
DESTINATIONS
ACTIVITIES
PLANNING
ABOUT
CONTACT
ENJOY THE SOLITUDE AND SOLACE OF
ARCTIC WILD
EXPLORE BELOW
RAFTING TRIPS
BASE CAMP TRIPS
BACKPACKING TRIPS
CANOE TRIPS
PHOTOGRAPHY TRIPS
CUSTOM TRIPS


ART
permanent collection
collections online
exhibitions
provenance
EVENTS
calendar
film
music
PROGRAMS
education dept.
institute (IAC)
LACMA lab
STORES
MEMBERSHIP
I
NFORMATION
gen. info / tickets
guest book
support LACMA
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special support groups
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PRESS


{% extends "example/base.html" %} {% load url from future %} {% block content %}
Ok, here is the link you have to use to reach your authorization page and beg for an authorization token
Now click, give your authorization and see you later, possibly with an access token
{{ authorization_link }} {% else %}(At this point, you should have created an Application instance on your side, up and running.)
{% if not error %} {% endif %} {% endif %} {% endblock %}


If ghyll scambling is your thing then Stickle Ghyll is a great place to explore starting at the New Dungeon Hotel and finishing off at Stickle Tarn to be met by the towering peaks of Pavey Ark and Harrison Stickle
Visit the extraordinary Aira Force Falls at Ullswater in the Lake District. View the almighty falls and then take a more leisurely steamer across the lake at Ullswater
Head into the Yorkshire Dales National Park to see the magnificient Ingleton Falls and enjoy the surrounding peaks
"This is fantastic! Wonderful pictures!"
"I've visited so many new places since visiting this website!"
"I can't wait to get started on some new adventures!"


What is CoGe?
CoGe's name is derived
from the phrase "Comparative Genomics" which is the field of computational
biology that is centered on the discovery of patterns in genomes through
intergenomic comparisons. These
patterns are interesting because they reflect the function or evolutionary
history of genomes or genomic regions.
Examples of such genome patterns are:
1. Series of
orthologous/paralogous genes that have a conservation of order in a
genome. Two or more genomic
regions (either within the same organism or between different organisms) that
have a conservation of gene order is indicative that the genomic regions shared
a common ancestral genomic region.
Such regions are called syntenic and in the case of intragenomic
detection, are used to determine if an organism experienced a genome
duplication event.
2. Conserved
Non-coding Sequences around orthologous/paralogous genes. These sequences are presumed to be
under evolutionary selective constraints because they have a function (probably
involved with the regulation of gene expression either directly through the
recruitment of transcription accessory factors/proteins or indirectly through
chomatin remodeling.)
CoGe was designed in
order to simplify access to genomic information and the development of
computational tools for use in comparative genomics.
There are already
many existing databases and tools for accessing genomic information. Why make another set of resources?
A current limitation
of many genome databases is their organism centric organization. For example, Ensembl's genome database
is designed to store a single organism's genome; thus requires a separate
installation of their database for each genome. This approach limits the tractability and maintainability of
genomic information as each new genome or new release of an existing genome
requires a separate database installation. Likewise, this "one genome–one database" approach also
limits the development and deployment of new comparative genomics tools. If new tools or data organization
schemas are developed for one genome, redeploying them for previously existing
genomes requires patching each installation separately. Here we propose to develop a new
database and application programming interface (API) to store any genome in one
unified system.
The principal
objective of this effort is to design a relational database schema that allows
for the tracking of any genome in an organism non-specific manner that also
allows for the co-existence of multiple versions of the same genome. By have a unified database for all
genomes, any tool developed for analyzing one organism's genome is immediately
available to all genomes in the database.
This approach also makes the development of comparative genomic tools
easier by having all genomic information in one centralized location, and
similarly, if comparative genomic tools are developed to analyze one set
of genomes, they are immediately available to any set of genomes.
What is in CoGe
system?
CoGe is a collection
of software resources that includes a database, visualization packages, and
analysis tools. These items can be
used to create software tools to access and analyze genomic information in any
number of ways. Tools that we
develop tend to fall into three general categories: APIs, command-line tools, and web-based tools. The APIs (application programming
interfaces) are an on-going collection of libraries used to access genomic
information in the CoGe database, generate visual representation of genomic
information, and give access to other informatics tools and algorithms
developed in-house. Command-line
tools usually center around data import and export from the genomes
database. Web-based tools utilize
web 2.0 design principles to make interactive and easy–to-use comparative
genomic analysis and visualization tools.
These tools are made available for general use on the CoGe web-site.
What software
models, databases, and languages are used by CoGe?
The CoGe database is
written for MySQL. Its design
focuses on minimizing data redundancy and maximizing data retrieval speeds
while maintaining simplicity of data structures and relationships. The core of the CoGe database centers
on the storage of any genome, paying attention to the need to accommodate
genomes for different sources (e.g. genbank, TIGR, JGI, Ensembl), multiple
datasets for a given genome (e.g separate datasets for each chromosome,
additional annotation information for a given genome), and accommodating
multiple versions of a given genome (although data quality should increase as a
function of time, analyses performed on old datasets require old the old
datasets for subsequent validation efforts).
APIs, components of
web-tools, and most command-line tools are written in PERL. PERL's near ubiquitous presence in web applications
and bioinformatics, extensive additional libraries for performing web-based and
database transactions, and large user base makes it an ideal language for
CoGe. We use PERL's object
oriented programming style extensively as well as POD for API documentation.
Additionally, we use
javascript, AJAX, and Web 2.0 design principles for designing easy-to-use,
desktop-like web-based tools.
How is the CoGe
genomes database organized?
We have made great
efforts to keep the design of the database for storing and accessing genomic
information simple while not compromising performance. The core part of the database (those
tables that store genomic information specifically) consists of 13 tables. The central concept around which all
other information orbits is genomic "features". A genomic feature merely refers to some genomic region to
which additional information is attached.
Take a "gene" as an example.
Although the specific definition of a gene varies, abstractly it refers
to a genomic region that contains biologically functional information. This information, when read through a
process called transcription, gives rise to the creation of RNAs. These RNAs either carry out some
cellular function (such as tRNAs and rRNAs) or encode information for use in
creating proteins through the process of translation. Thus, in order to track a region of a genome that has
associated additional information, all we need to know is its location. If you look at the schema for the CoGe
genome database, you will see a relationship between the feature table and the
location table. The feature table
stores only three types of information, the internal database id of a feature
(each feature gets a unique id), the feature_type_id which links a feature to
the feature_type table (although you can probably guess the information stored
in that table, we will go into more detail of the feature_type table further on
in this discussion), and the data_information_id (which is the dataset from
which the feature was obtained). The
location table stores the information about the position of the feature: the chromosome from which it is
derived, the start position (nucleotide coordinates), the end position, the
strand (+/1 for top strand, -/-1 for bottom strand), and the feature database
id (feature_id) to which the location belongs. The relationship between the feature and location tables is
a "one to many" relationship where one feature can have more than one location
associated to it. The reason for
this will become clear in a moment.
Some genes contain
information for transcribing more than one RNA where different RNAs use
different genomic sequence contained within the gene. In order to track this kind of information (aka alternative
splicing), we need to specify additional genomic features for each RNA. However, since not all of the DNA
sequence of the gene is necessarily used for a given RNA, we may need to track
different genomic locations for the gene and each RNA. To do this, we can specify a unique
feature for the gene and each RNA, and specify the appropriate genomic
location(s) used for each. By
having a one to many relationship between the feature and location tables, we
can accommodate all this information.
For example:
GeneA: Chromosome 1, Strand 1, Position (1000-10000)
RNA_A1: Chr 1, Strand 1,
Position (1100-3000,4000-5000,8000,-9500)
RNA_A2: Chr 1, Strand 1,
Position (1100-3000,4000-6000,7000-7500,8000,-9500)
To extend this example
further, assume that each RNA listed above encodes a protein. However, not all of the information
that is transcribe into RNA is necessarily translated into protein. In this case, we can specify additional
features for just the protein coding region using the same process that was done
for the RNA coding regions.
One thing that you may
have noticed from this example is that we specified several different kinds of
genomic features: genes, RNAs and
proteins coding regions (aka CDS).
However, it is easy to find several more examples of different types of
genomic features. For example,
there are several different types of RNA genes besides those that code for
proteins (aka mRNA): tRNA, rRNA,
micro RNA, snRNA, snoRNA, etc.
Additionally, there are several genomic features that don't code for
RNA, but are useful to track because they have function. A TATA-box is such an
example of a genomic feature.
TATA-boxes are genomic regions that contain the information needed to
position RNA polymerases (usually RNA pol II) correctly in order to transcribe
a gene in eukaryotic transcription systems.
In order to track this
kind of information (different types of features), there is a table in the CoGe
genomes database designed just for that purpose: the feature_type table. This table has three types of associated information: the internal database id of the feature
type, the name of the feature type (e.g. mRNA), and the description of the
feature type (usually not used, but good to have just in case.)
One problem with genomic
features is the plethora of alternative names that may be used to refer to a
single feature. To accommodate
this, there is a table in the database called feature_name. Each entry in this table contains a
name and description (optional) for a feature and is linked to the feature
table with a one-to-many relationship (i.e. one feature entry can have multiple
feature_name entries.)
At this point, we have
specified the central concept of the CoGe genomes database: the genomic
feature. A feature needs to be of
a particular type (feature_type table), has genomic coordinates (location
table), and one or more names (feature_name table). In addition to this information, there are additional kinds
of information that can be associated with a feature. Generally, this additional information breaks into type
types: specific sequences (e.g.
translated protein sequence) and annotations. If a feature has a specific non-DNA sequence associated with
it, such as a protein sequence, this information can be stored in the sequence
table. The sequence table in turn
is associated with the sequence_type table to store the name and description of
the type/kind of sequence.
The term "annotation" is
a broad category of associated information about a gene that is gathered
through experimental and computational analysis of a genomic feature. Some types of annotations are
functional information, database references, literature references, cellular
locations, etc. In order to track
this kind of information in a flexible yet organized manner, a three level
annotation schema is employed. At
the root is the annotation table which stores an annotation, the feature to
which it belongs, and the type of annotation (stored in the annotation_type
table) that it is. In order to
organize types of annotations, there is an annotation_type table that has the
name and description of the type of annotation. Additionally, annotation_types can be grouped into broader
categories using the annotation_type_group table. This tree-tiered approach allows maximum flexibility for
specifying annotations, types of annotations, and groups of types of
annotations.
An example of this
three-tiered annotation approach is well suited for Geneontology
annotations. Let us say we have
the following annotation for a gene:
go_function: nucleic acid binding [goid
0003676].
For this annotation, we
can create an annotation_type_group with the name of "go_function", an
annotation_type with the name of "0003676" and description "goid", and the
annotation will be "nucleic acid binding". Using this type of a schema, it makes finding all
annotation_types with an annotation_type_group of "go_function" trivial. Likewise, it because easy to find all
features with an annotation_type of "0003676".
The next major section
of the CoGe database is for storing information about a dataset, the organism
to which it belongs, and the actual genomic sequence. The key table for this information is the data_information
table. Although this table should have
been called the dataset table, the primary information this stores is the name,
description, and version of a given dataset. Though it the data_source, feature, organism, and
genomic_sequence tables are linked.
The data_source table stores the name, description and web-link of a
source providing genomic data (e.g. genbank, JGI, TIGR, Ensembl). The organism table stores the name and
description of an organism (e.g. Arabidopsis thaliana, Escherichia coli); the genomic_sequence table stores the genomic
sequence. Since genomes can be
large (the human genome is ~3,000,000,000 base pairs), genomic sequence is
broken into chunks (usually 10,000 nucleotides).
Using this schema to
store genomic data allows for storing genomes in any number of
configurations. For example, a
genome (and all chromosomes contained therein) can be provided as a single file
or multiple files (e.g. one chromosome per file). Also, multiple versions of a genome can be stored by
specifying the "version" column of the data_information table. And finally, additional
feature/annotation files can be stored that are associated with a version of a
genome, but do not actually contain genomic sequence (e.g. an annotation file
of all protein domains in a genome).
How do I get a copy
of the API, genome database, end-user tools, etc?
As the CoGe system is
still in its early phases of development, we have not yet had time to finish
the documentation of the various components, package up the API, example
scripts, data files, etc. for general release. However, we would be more than happy to provide you with
anything you might find helpful.
Just send an e-mail to elyons(@)nature.berkeley.edu (remember to remove
the "()" around the "@" symbol.)


This may turn out to be important to anyone with a moderate dependence to opiates. For my own sake, I hope so, but the initial data seems very encouraging!
History: Decided to start taking Hydrocodone/APAP about 2 months ago for experimental purposes. Personally, I am one who does not get a euphoric rush from opiates, at least not recently. The first time I had taken any was several years ago before any experimentation and subsequent alteration to my brain and body chemistry. At that time, I had only about 10 Vicodin, not knowing the Hydro content, but only a half gave me a good groove, and I spread them out over several weeks, adding them to whatever else I was doing, usually extacy, but this is focused on Hydrocodone and my experimentation with it.
After about the first month starting my Hydro, I already had physical dependence. Not taking my next dose, which daily had risen quickly to about 100mg/day : (10) Norco 10/325, left me with initial lethargy, irritableness and VERY BAD intestinal discomfort. Let me just add that while taking any opiates, I suggest also taking daily swigs of Senokot laxative or Senna tablets to keep you from becoming dangerously constipated.
Immodium AD can be used to offset this physical, what I call intestinal withdrawl, but that causes constipation as well. Don't take opiates and Immodium at the same time! You'll not go to the bathroom for a month! This is extremely not a pleasant experience.
I am still not sure about supplementing DXM with opiate use to decrease dependence. I never took the Robitussin Gel Caps steadily enough to know for sure.
During my initial time taking Hydro, those first two months or so, there was very little pleasure other than warding off the withdrawl symptoms, just a little relaxed feeling someone who needed a smoke would understand.
I eventually was unable to get any more Hydro and went through withdrawls for real for about a week, each day a bit better than the last. But in order to get through it, I kept knocking myself out with Xanax ... just to sleep through the pain. Needless to say, I was not very productive during this time, but I got through it without substituting a habit of Xanax in it's place, and I have ALOT of Xanax.
But during my constant usage of Hydro, I needed something to offset the sleepiness it gave me, so I tried adding Pseudoephedrine. This made me feel sick for the most part, and the little lift it gave was not worth it, for me.
Well, wouldn't you know that after I thought I was through with all this silliness, I went and got another refill of Hydro. This is all through online pharmacies, by the way. So now here I am finishing the last 20 or so of the 90 I got only a couple weeks ago. Once again, the knowledge of painful withdrawl haunts me. However, I think I discovered something that may take care of this, Provigil (Modafinil).
The other night, I was working late as I regularly do, and I was going to reach for the Pseudoephedrine, when I searched out a vial of Provigil I had lurking in my stash. I've had this for quite awhile to offset the lethargy from SSRI's I was taking at the time, but the combination didn't seem to agree with me. But now it's a different ballgame, and like everything else, I decided to give it another try.
While mildly buzzing on my steady dosing of Hydro, I took 100mg of the Provigil. All my pills are broken in half, as the standard 200mg was way too much back when first trying it. I sat back down in front of the computer, as I am now, and to my utter surprise, I started to feel giddy and motivated, and the slothy, polluted feeling of the Hydro lifted off me like removing a wet sweater.
I thought I found a great combination to go with my Hydro, but again, to my surprise, it seems to NEGATE the opiate. I'm still trying to figure this out for sure, but today I had a dentist appointment (no, i didn't get any drugs) and instead of grabbing my Hydro that i hadn't had for the last few hours, I instead started to clean off the Halloween decorations from the porch (It's now December), take out the trash, fix some things, etc.. etc.. I didn't even care for a smoke as much.
So, my hope and initial feeling is this: taking Provigil could help you get off Hydro at least, maybe other opiates. It has a cleansing feeling, and I think it's going to work much better than doping myself with the Xanax like last time! And, at the very least, I keep working and working. Provigil may have many more surprises in store.
Experience Reports are the writings and opinions of the individual authors who submit them.
Some of the activities described are dangerous and/or illegal and none are recommended by Erowid.


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