Chapter 15 ASRM 2016
ASRM 2016은 미국생식의학회에서 주최하는 생식의학 관련 가장 큰 학회입니다.
https://drive.google.com/open?id=0B7BS_yg2ja1EeUFxWkxFWVU3dEE
15.1 Plenary lectures
15.1.1 Plenary 2
- speaker: Camran Nezhat, M.D. Lectureship in Innovations in Medicine
- speaker: Diana W. Bianchi, M.D. Tufts University School of Medicine (NICHD director, soon-to-be)
- Maternal Plasma DNA Sequencing
- Noninvasive prenatal genetic testing using analysis of cell-free DNA in maternal plasma has translated to and transformed clinical care.
- importance of positive and negative predictive values
15.1.2 Plenary Lecture 3 : The importance of Long-acting reversible contraception (LARC)
- speaker: Jeffrey F. Peipert (Indiana University)
- Unintended pregnancy = High-risk pregnancy
- Less likely to seek prenatal management
- Huge difference among countries - Sexual activity = Similar (US and Sweden)
- Teen birth 는 감소하고 있다.
- Common contraceptive method - OCP, Sterilization , Condom, Vasectomy
- IUD, DMPA, Implant - highly effective
- LNG-IUS ~ 5y, Copper ~ 10y, Implnat - 3y
- Myths - infection, infertility, pain, cancer,
- Providers - litigation fear
- Safety
- IUD does not cause PID (Only first month)
- IUD does not cause infertility (Chlamydia - infertility)
- Etopic pregnancy - Actually reduce!
- Actually lower risk of endometrial, cervical cancer
- Poor candidates for IUD - puerperal sepsis, post septic abortion, unexplained vaginal bleeding, current cervitis, chlamydia
- Adolescents - encourage use of dual
- Etonogestrel implant - subdermally implant (NEXPLANON)
- inhibits ovulation
- <1%
- didn’t vary by BMI status
- discontinuation - bleeding irregulatities
- Contraceptive Choice Project
- Promote LARC use
- 50% believe IUC is safe
- 10,000 participants (4 years) CHOICE study
- 2000 teenagers
- 75% chose LARC.
- NEJM published (2 papers)
- Very reliable - especially teenagers
- Decreased repeated abortion
- Race disparity can be minimized.
- Edutcation, Access, Costs & LARC-friendly providers
- Dissemination strategies - Short videos
Summary
- Unintended pregnancy and teen pregnancy continue to be important health problems in the United States.
- Long-acting reversible contraception (LARC) is one strategy that has proven to be effective, yet underutilized.
15.1.3 Plenary 4
- speaker: Jay Ross Kaplan, Ph.D. Wake Forest School of Medicine
- CV (CHD and stroke) - not just for men
- WISE study - endogenous estradiol in premenopausal women w or wo CHD
- Conclusions from epidemiology of sex differences in CHD
- Pre- and sugically postmenopausal monkeys
- Subclinical ovarian dysfunction - relatively common in premenopausal monkeys - precocious acceleration of atherosclerosis.
- Exogenous hormones (OCs) mitigate this effect.
- Estrogen treatment immediately following ovariectomy inhibits atheosclerosis; delayed treatment ineffective - perhaps because lesions are larger.
- CHD risk in pre- and early post-menopausal women - ELITE tiral and numerous re-examinations of existing trials.
15.1.4 Plenary 5
- speaker: Jan Deprest, M.D., Ph.D., F.R.C.O.G. - University of Leuven
- Fetal surgery
- Obstetical endoscopy - TTTS
- Angiogram showed “Third” circulation.
- “Chorangiopagus” - donor (oligohydramnios) recipient (polyhydramnios)
- Ultrasound screening programs can pick up congenital malformations, of which some are eligible for prenatal surgical repair.
- Some procedures are possible by fetoscopy, while others require a hysterotomy.
- impact of fetal surgery on the future reproductive life of the mother
- MOMS trial - 12mo outcomes (prenatal surgery, postnatal surgery) - uterine dehiscence (10%) !!!!
- Congenital diaphragmatic hernia - lethal pulmonary hypoplasia - fetoscopic surgery (tracheal occlusion)
Future
- Fetal surgery - fails in ~40% of cases -> Novel target discovery - gene expression analysis
- Explorer candidate medical Tx. -> Viagra
Conclusion
- Fetoscopy is a clinical reality (few materal Cx <1%)
- Open surgery (high materal morbidity)
15.1.5 Plenary 6 Update on Congenital Adrenal Hyperplasia
- Maria I. New, M.D. -> Icahn School of Medicine at Mount Sinai
- SRY (Y chromosome) Sertoli - MIF (Mullerian Inhibiting Factor -> supress tubes) -> Mullerian regression
- Leydig cells -> testosterone -> DHT (Penis, scrotum)
- 17OH Progesterone (CAH screening)
- bone age advancement, rapid growth
- Classical diseases
- Congenital adrenal hyperplasia is a common inherited form of adrenal insufficiency due to mutations (genetic defects) in the genes coding for several enzymes needed to produce vital adrenal cortex hormones.
- such as drug therapy with androgen-blocking effects and growth hormone to delay puberty, as well as surgical options, including prenatal therapy.
15.1.6 Plenary 7 - Why Parents Matter (Epigenetically): Genomic Imprinting in Health and Disease
- Marisa S. Bartolomei, Ph.D.
15.1.7 Plenary 8: AUA Bruce Stewart Memorial Lecture: The Futures of (Male(Reproductive)) Medicine
- Craig Niederberger, M.D., F.A.C.S.
- stackoverflow - advance all elements in a Range in Swift
- WOLFRAM Mathematica
- second order differential mathematics
- Wolfram Alpha
- Raspberry Pi
- RASPBERRY PI ZERO: THE $5 COMPUTER
- Medical Therapy - prior to TESE
- the future of reproductive medicine
- Urine pressure checker by Raspberry Pi
- Sperm analysis by automated machine
- Future shock by Alvin Toffler
15.2 Prize Oral
15.2.1 mTOR inhibitors preserve fertility in a murine model : a novel pharmacologic approach to fertility preservation during gonadotoxic chemotherapy
- Kara Goldmann (NYU) Schneider lab
- diminished ovarian reserve
- PI3K -> AKT -> mTORC1
- mTORC1 inhibitors (Everolimus) - breast cancer
- mTOR inhibitor 단독은 부작용 있지만, cyclophosphamide가 ovarian reserve를 보존할 수 있다
- rodent experiment
- AMH - (when increased, ovarian reserve decreased)
- Cytoxan단독은 AMH 낮추나 복합은 여전히 높아져 있음
- RAD INK daily CY(cyclophosphamide) RAD+CY INK+CK
- mTOR inhibitors preserved fertility
15.2.2 Verification of accuracy & safety for ovarian reserve assessment with optical coherence tomography using mouse ovary
- Seido Takae
- establishment of standard follicle imaging
- Safety of OCT - No impact on IVF outcome
- Clinical Trial - vitrification - aplastic anemia (15/F)
- Young cancer or POI patient can be benefited (Ovariectomy)
- Laparoscopy
15.2.3 O-6 RANDOMIZED CONTROLLED TRIAL OF LOW (5%) VS. ULTRALOW (2%) OXYGEN TENSION FOR IN VITRO DEVELOPMENT OF HUMAN EMBRYOS
- speaker: Daniel Kaser
- 5% - oviduct
- 2% - uterine
- How about culturing environment? 배양도 같은 방법으로 해야 하나?
- Design : 5% O2 (D1-D3) -> 5% vs 2% O2 (D4~ )
- Primary endpoint: Embryo stage and grade
- Secondary endpoint: Spent media analyses
- These findings support our hypothesis that blastocyst yield and quality may be superior when O2 tension is reduced from 5% to 2% on day 3, thereby recapitulating the O2 environment in vivo.
15.3 Symposium : Overview of Food and Drug Administration (FDA) Regulations of Products Used to Treat Reproductive Conditions in Women
- panel: Yun-shang Piao, Ph.D., R.A.C., Rhonda M. Hearns-Stewart, M.D., Shelley R. Slaughter, M.D., Ph.D., Monica Garcia, Ph.D., Michael T. Bailey, Ph.D.
15.3.1 Richard D. McFarland, M.D., Ph.D.
- OTAT - Office of Tissues and Advanced Therapies
- Cellular therapies, Cancer vaccines etc
- Human cells, Tissues (HCT/Ps)
- Two regulatory tiers
- “361 HCT/P”
- Drugs, devices and/or biological products
- 2667 registered (mostly HPC, blood bank)
- Relavant communicable disease agents or disease (RCDADs) - HIV-1,2, HBV, HBC, syphilis,
- Donor eligibility (DE) determination
- DE exception (Cells and tissue for autologous use, by sexually intimate partner..)
- Recent final guideline
- Syphilis Testing - FDA-licensed, approved or cleared donor screening tests
- WNV(West Nile Virus) Testing - licensed NAT donor screening test (June - Sep)
- HBV NAT - FDA-licensed NAT donor screening test
- ZIKV Screening - immediate implementation guidance
- 지금까지는 Subpart C, 지금부터는 Subpart A
15.3.2 Rhonda - CDER Drug review process
- speaker: Rhonda
- Important regulatory milestones
- 1906 - Pure Food Drugs Act
- 1938 - FDC (The Act)
- 1951 - Durham-Humphrey Amendment - prescription drug (habit forming, potentially harming drug)
- 1962 - Kefauver-Harris Drug Amendment - all new drugs must also establish efficacy
- 1984 - Hatch
- 1992 - prescription drug user fee act (PDUFA 프두파)
- 2007 - FDA Amendments Act (FDAAA 파다)
- CDER responsibility
- Investigational New Drug (IND) - how can an unapproved new drug be tested in clinical trials?
- IND - need or not? - Lawfully marketed? Off-label? Treat patient?
- Cover, TOC, Introductory statement and general plan, IB, Tox,
- 30 day safety review - are the risk to the clinical participant acceptable? adequate safety monitor? - Clinical Hold (deficiency)
- NDA - efficacy, safety - 505(b)(1), 505(b)(2)
- Evaluation that all requirements for submission have been met and that NDA is well orgenized
- Multi-disciplinary approach - Multiple levels
- 74-day letter
- Physician labeling - PLR (Physician labeling reult)
- REMS (risk evaluation and mitigations strategies) - REMS for NDA - medication guide, communication plan, implementation
- ETASU (elements to assure safeuse) - specific training
- Phase 4 : postmarketing requirements
- information on regulation of medical products intended for assisted reproduction
- Center for Biologics Evaluation and Research (CBER), Center for Drug Evaluation and Research (CDER), and Center for Devices and Radiological Health (CDRH)
15.3.3 CDRH (Center for Devices and Radiological Health)
- Monica
- Medical device - isn’t metabolized.
- Classification - Class I (Low risk)-premarket review not required, II (Intermediate) - Petri dishes etc - typically required, III (High) - PMA required.
- OB/GYN devices branch - ART devices, vaginal lubricants etc…
- 21 CFR Parts 884.6100 - 6200 subpart G
- Class II - substantially equivalence to another marketed devices. - Same intended use, technological characteristics
- MOA, Materials/components, Engineering schematics, Design specifications
- 510(k) submission -
- Device description,
- Labeling (False/misleading claims, instructions for use)
- Sterilization (Method, validation, package integrity)
- Shelf-life (duration of proposed shelf-life, performance), biocompatibility (patient contact, duration of contact)
- Electical safety, electromagnetic compatibility
- ART II special controls - design spec, MEA(Mouse embryo assay), HSSA(human sperm survival assay), endotoxin testing
- 510(k) outcomes - SE (substantially equivalence) | NES, try again | NSE
- Device clearance after SE outcome
- De Novo - the newest way for devices to come to market
- When come to FDA?
- Presubmission program for interactive feedback from FDA - regulatory pathway,
- Investigation Device Exemption (IDE)
- fda.gov/Tranining/CDRHlearn
15.3.4 Endometriosis, Tuesday EXPO theater
- ESHRE, European Society of Human Reproduction and Embryology (2014),
- WES(World Endometriosis Society), Consensus on current management of endometriosis (2013) - Consensus on current management of endometriosis.
The case for surgical diagnosis of endometriosis - Diamond
- Michael Diamond, MD - Pelvic pain DDX - Endometriosis, fibroids, adenomyosis, adhesions, PID (gynecologic) IBS, Intestitial cystitis, fibromyalgia (non-gynecologic)
- Most accurate technique for diagnosis -> laparoscopy with histological confirmation
The case for clinical diagnosis of endometriosis - Surrey
- mean - dianosis, 9.3y, 5 patients
- Ultrasound findings - 81% PPV (K - 0.58)
- Description of pain (throbbing …)
- Symptoms of women undergoing surgery -> dysmenorrha etc (high)
- Can response to medication be used to diagnose endometriosis? GnRH agonist or OCs.
- Dr. Surrey’s proposed diagnostic algorithm
Discussion
- Diamond - Ix of GnRH agonist - absense of pathology apparent by noninvasive diagnostic modalities
- Surrey - Ix of laparoscopy - suspicious or symptomatic adnexal mass, failure to respond to second-line therapy, management of fertility as primary concern, clear evidence of deeply invasive disease
15.4 Scientific Congress Prize Paper Session 2
15.4.1 O-91 PREOVULATORY PROTEIN RESTRICTION (PPR): DISRUPTED AMINO ACID (AA) KINETICS AND MITOCHONDRIAL STRUCTURE AND FUNCTION IN THE RAT OOCYTE
- speaker: Amy Schutt - Baylor College
- Maternal dietary intake critically supports the oocyte through maturation, fertilization and until embryo genome activation.
- PPR -> profound changes in amino acid metabolism and COC mitochondrial structure and function in the rat.
- Amino acid kinetics in the oocyte
- decreased ability to increase antioxidant precursor production
- lack of effective compensation in the setting of protein starvation.
- LP oocyte is vulnerable to oxidative stress as it cannot increase GSH production.
- abnormal COC mitochondrial ultrastructure and
- altered oocyte expression of genes related to mitochondrial biogenesis.
15.4.2 O-92 EFFECTS OF RESVERATROL ON POLYCYSTIC OVARY SYNDROME
- speaker: Antoni Duleba (University of California, San Diego)
- Hyperandrogenism is the central feature of PCOS
- isolated ovarian theca-interstitial cells demonstrated that resveratrol, a natural polyphenol, inhibits mRNA expression of Cyp17a1 and reduces androgen production
- evaluated endocrine and metabolic effects of resveratrol on women with PCOS.
- Prospective double-blind, randomized, placebo-controlled trial.
- clinical trial evaluating the effects of resveratrol on PCOS
- Resveratrol significantly reduces serum levels of testosterone and DHEAS
- effect on ovarian as well as adrenal androgen production.
- improvement of insulin sensitivity and a decline of insulin level
15.4.3 O-93 GENOME-WIDE DNA METHYLATION CHANGES IN MOUSE ZYGOTES ASSOCIATED WITH SUPEROVULATION
- speaker: Bo Yu (University of Washington, Seattle)
- Assisted Reproductive Technologies (ART) procedures can result in abnormal methylation of some imprinted genes in early embryos.
- genome-wide effect
- to identify DNA methylome changes in pre-implantation mouse embryos after ovarian hyperstimulation
15.4.4 O-94 CAN WE EXPECT TO IMPROVE AGE AT MENOPAUSE PREDICTIONS WITH REPEATED AMH MEASUREMENTS?
- speaker: Annelien de Kat (University Medical Center Utrecht, Utrecht, Netherlands)
- high AMH -> late menopause, low AMH -> early menopause
- AMH decline rate
- Repeated measures of AMH levels
- Anti-M€ullerian hormone (AMH) levels are considered to be an **indicator of ovarian aging
- unraveled longitudinal decline trajectories of AMH with age.
- 1,857 women enrolled in the prospective, population-based Doetinchem Cohort Study, with a known age at natural menopause (ANM)
- picoAMH assay (AnshLabs) in a total of 7,666 plasma samples
- Time to menopause
- modeled with the use of mixed model analyses, taking non-linear changes of AMH with age into account for each individual
- longitudinal study confirms the overall association of AMH levels with time to menopause, while taking into account individual AMH changes with time
15.5 Oral Presentation
15.5.1 O-229 THE IMPACT OF ELAGOLIX ON QUALITY OF LIFE IN WOMEN WITH ENDOMETRIOSIS-ASSOCIATED PAIN: RESULTS FROM TWO RANDOMIZED, PLACEBO-CONTROLLED STUDIES USING THE ENDOMETRIOSIS HEALTH PROFILE QUESTIONNAIRE (Hugh Taylor)
15.5.3 O-231 NEW PROCEDURE FOR THE ENDOMETRIOSIS DIAGNOSIS
- speaker: Xavier Santamaria
- mouse model - midventral incision, suture with peritoneal cavity
- GFP - endometriotic cells, CD45 - leukocytes
- LGR5 - transmembrane orphan receptors - microarray에서 control과 두드러진 차이 보임.
- human : in silico study : affymetrix HG U133 Plus 2.0 Arrays
- Co-localization with LGR5,
- none in donor vs high in endometriosis patient
- LGR5+ endometriosis vs LGR5- endometriosis
- Monocyte –(differentiation)–> macrophage, monocyte-derived DCs
- Conclusion
- LGR5+ cells co localized in stroma of human eutopic endometrium
- immune system, adhesion molecules, migration pathways were differnetially expressed.


'发生错误',
'The page you are looking for is temporarily unavailable' => '你所浏览的页面暂时无法访问',
'You can return to the previous page and try again' => '请检查是否操作有误、若还有疑问、请直接与我联系！'
];
?>
=$lang['An error occurred']?>
=$debug?$message:$lang['The page you are looking for is temporarily unavailable']?>
=$lang['You can return to the previous page and try again']?>


Create a new API Gateway for use by Services. When publishing a Service, at least one Gateway must be specified so that service configuration details can be published to the appropriate place.


| Modifier and Type | Method and Description |
|---|---|
TransformProcess.Builder |
TransformProcess.Builder.transform(Transform transform)
Add a transformation to be executed after the previously-added operations have been executed
|
| Constructor and Description |
|---|
DataAction(Transform transform) |
| Modifier and Type | Class and Description |
|---|---|
class |
NDArrayColumnsMathOpTransform
Perform an element wise mathematical operation on 2 or more NDArray columns
|
class |
NDArrayDistanceTransform
Calculate the distance (cosine similarity, EUCLIDEAN, MANHATTAN) between two INDArrays
|
class |
NDArrayMathFunctionTransform
A simple transform to do common mathematical operations, such as sin(x), ceil(x), etc.
|
class |
NDArrayScalarOpTransform
Perform an NDArray/scalar element wise operation, such as X.addi(scalar).
|
| Modifier and Type | Class and Description |
|---|---|
class |
ReduceSequenceTransform
Reduce The values in each column in the sequence to a single value using a reducer.
|
| Modifier and Type | Class and Description |
|---|---|
class |
BaseSequenceExpansionTransform
A base class for sequence expansion operations.
|
| Modifier and Type | Class and Description |
|---|---|
class |
SequenceTrimToLengthTransform
Trim or pad the sequence to the specified length (number of sequence steps).
|
class |
SequenceTrimTransform
SequenceTrimTranform removes the first or last N values in a sequence.
|
| Modifier and Type | Class and Description |
|---|---|
class |
ReduceSequenceByWindowTransform
Idea: do two things.
|
| Modifier and Type | Method and Description |
|---|---|
Transform |
BaseSerializer.deserializeTransform(String str)
Deserialize a Transform serialized using
BaseSerializer.serialize(Object) |
| Modifier and Type | Method and Description |
|---|---|
List<Transform> |
BaseSerializer.deserializeTransformList(String str)
Deserialize a Transform List serialized using
BaseSerializer.serializeTransformList(List) , or
an array serialized using BaseSerializer.serialize(Transform[]) |
| Modifier and Type | Method and Description |
|---|---|
String |
BaseSerializer.serialize(Transform[] transforms) |
| Modifier and Type | Method and Description |
|---|---|
String |
BaseSerializer.serializeTransformList(List<Transform> list)
Serialize a list of Transforms
|
| Constructor and Description |
|---|
TransformList(List<Transform> list) |
| Modifier and Type | Class and Description |
|---|---|
class |
BaseColumnsMathOpTransform
Base class for multiple column math operations.
|
class |
BaseColumnTransform
Map the values in a single column to new values.
|
class |
BaseTransform
BaseTransform: an
abstract transform class, that handles transforming
sequences by transforming
each example individually
|
| Modifier and Type | Class and Description |
|---|---|
class |
CategoricalToIntegerTransform
Created by Alex on 4/03/2016.
|
class |
CategoricalToOneHotTransform
Created by Alex on 4/03/2016.
|
class |
FirstDigitTransform
FirstDigitTransform converts a column to a categorical column, with values being the first digit of the number.
|
class |
IntegerToCategoricalTransform
Convert an integer column to a categorical column, using a provided
Map<Integer,String> |
class |
PivotTransform
Pivot transform operates on two columns:
- a categorical column that operates as a key, and
- Another column that contains a value
Essentially, Pivot transform takes keyvalue pairs and breaks them out into separate columns.
|
class |
StringToCategoricalTransform
Convert a String column
to a categorical column
|
| Modifier and Type | Class and Description |
|---|---|
class |
AddConstantColumnTransform
Add a new column, where the values in that column for all records are identical (according to the specified value)
|
class |
DuplicateColumnsTransform
Duplicate one or more columns.
|
class |
RemoveAllColumnsExceptForTransform
Transform that removes all columns except
for those that are explicitly
specified as ones to keep
To specify only the columns
to remove, use
RemoveColumnsTransform |
class |
RemoveColumnsTransform
Remove the specified columns from the data.
|
class |
RenameColumnsTransform
Rename one or more columns
|
class |
ReorderColumnsTransform
Rearrange the order of the columns.
|
| Modifier and Type | Class and Description |
|---|---|
class |
ConditionalCopyValueTransform
Replace the value in a specified column with a new value taken from another column, if a condition is satisfied/true.
|
class |
ConditionalReplaceValueTransform
Replace the value in a specified column with a new value, if a condition is satisfied/true.
|
class |
ConditionalReplaceValueTransformWithDefault
Replace the value in a specified column with a 'yes' value, if a condition is satisfied/true.
|
| Modifier and Type | Class and Description |
|---|---|
class |
BaseDoubleTransform |
class |
ConvertToDouble
Convert any value to an Double
|
class |
DoubleColumnsMathOpTransform
Add a new double column, calculated from one or more other columns.
|
class |
DoubleMathFunctionTransform
A simple transform to do common mathematical operations, such as sin(x), ceil(x), etc.
|
class |
DoubleMathOpTransform
Double mathematical operation.
|
class |
Log2Normalizer
Normalize by taking scale * log2((in-columnMin)/(mean-columnMin) + 1)
Maps values in range (columnMin to infinity) to (0 to infinity)
Most suitable for values with a geometric/negative exponential type distribution.
|
class |
MinMaxNormalizer
Normalizer to map (min to max) -> (newMin-to newMax) linearly.
|
class |
StandardizeNormalizer
Normalize using (x-mean)/stdev.
|
class |
SubtractMeanNormalizer
Normalize by substracting the mean
|
| Modifier and Type | Class and Description |
|---|---|
class |
BaseFloatTransform |
class |
ConvertToFloat
Convert any value to a Float
|
class |
FloatColumnsMathOpTransform
Add a new float column, calculated from one or more other columns.
|
class |
FloatMathFunctionTransform
A simple transform to do common mathematical operations, such as sin(x), ceil(x), etc.
|
class |
FloatMathOpTransform
Float mathematical operation.
|
| Modifier and Type | Class and Description |
|---|---|
class |
CoordinatesDistanceTransform
Computes the Euclidean distance between coordinates found in two columns, divided by an optional third for normalization purposes.
|
class |
IPAddressToCoordinatesTransform
Uses GeoIP2 from http://www.maxmind.com
to convert IP addresses to (approximate) coordinates (latitude:longitude).
|
class |
IPAddressToLocationTransform
Uses GeoIP2 from http://www.maxmind.com
to convert IP addresses to (approximate) locations.
|
| Modifier and Type | Class and Description |
|---|---|
class |
BaseIntegerTransform
Abstract integer transformation (single column)
|
class |
ConvertToInteger
Convert any value to an Integer.
|
class |
IntegerColumnsMathOpTransform
Add a new integer column, calculated from one or more other columns.
|
class |
IntegerMathOpTransform
Integer mathematical operation.
|
class |
IntegerToOneHotTransform
Convert an integer column to a set of one-hot columns.
|
class |
ReplaceEmptyIntegerWithValueTransform
Replace an empty/missing integer with a certain value.
|
class |
ReplaceInvalidWithIntegerTransform
Replace an invalid (non-integer) value in a column with a specified integer
|
| Modifier and Type | Class and Description |
|---|---|
class |
LongColumnsMathOpTransform
Add a new long column, calculated from one or more other columns.
|
class |
LongMathOpTransform
Long mathematical operation.
|
| Modifier and Type | Class and Description |
|---|---|
class |
TextToCharacterIndexTransform
Convert each text value in a sequence to a longer sequence of integer indices.
|
class |
TextToTermIndexSequenceTransform
Convert each text value in a sequence to a longer sequence of integer indices.
|
| Modifier and Type | Class and Description |
|---|---|
class |
ParseDoubleTransform
Convert string writables to doubles
|
| Modifier and Type | Class and Description |
|---|---|
class |
SequenceDifferenceTransform
SequenceDifferenceTransform: for an input sequence, calculate the difference on one column.
|
class |
SequenceMovingWindowReduceTransform
SequenceMovingWindowReduceTransform Adds a new column, where the value is derived by:
(a) using a window of the last N values in a single column, (b) Apply a reduction op on the window to calculate a new value for example, this transformer can be used to implement a simple moving average of the last N values, or determine the minimum or maximum values in the last N time steps. |
class |
SequenceOffsetTransform
Sequence offset transform takes a sequence, and shifts The values in one or more columns by a specified number of
times steps.
|
| Modifier and Type | Class and Description |
|---|---|
class |
AppendStringColumnTransform
Append a String to the
values in a single column
|
class |
BaseStringTransform
Abstract String column transform
|
class |
ChangeCaseStringTransform
Change case (to, e.g, all lower case) of String column.
|
class |
ConcatenateStringColumns
Concatenate values of one or more String columns into
a new String column.
|
class |
ConvertToString
Convert any value to a string.
|
class |
MapAllStringsExceptListTransform
This method maps all String values, except those is the specified list, to a single String value
|
class |
RemoveWhiteSpaceTransform
String transform that removes all whitespace charaters
|
class |
ReplaceEmptyStringTransform
Replace empty String values with the specified String
|
class |
ReplaceStringTransform
Replaces String values that match regular expressions.
|
class |
StringListToCategoricalSetTransform
Convert a delimited String to a list of binary categorical columns.
|
class |
StringListToCountsNDArrayTransform
Converts String column into a bag-of-words (BOW) represented as an NDArray of "counts."
|
class |
StringListToIndicesNDArrayTransform
Converts String column into a sparse bag-of-words (BOW)
represented as an NDArray of indices.
|
class |
StringMapTransform
A simple String -> String map function.
|
| Modifier and Type | Class and Description |
|---|---|
class |
DeriveColumnsFromTimeTransform
Create a number of new columns by deriving their values from a Time column.
|
class |
StringToTimeTransform
Convert a String column to a time column by parsing the date/time String, using a JodaTime.
|
class |
TimeMathOpTransform
Transform math op on a time column
Note: only the following MathOps are supported: Add, Subtract, ScalarMin, ScalarMax
For ScalarMin/Max, the TimeUnit must be milliseconds - i.e., value must be in epoch millisecond format |
| Modifier and Type | Interface and Description |
|---|---|
interface |
BagOfWordsTransform
A bag of words transform represents taking a list of words
and converting it to a vector where that vector is
of length number of vocab words.
|
| Modifier and Type | Class and Description |
|---|---|
class |
GazeteerTransform
A gazeteer is a work lookup table
based on a word list.
|
class |
MultiNlpTransform
A multi NLP transform takes in 1 or more bag of words transforms as a pipeline
and runs them in sequence.
|
class |
TokenizerBagOfWordsTermSequenceIndexTransform
This transform takes in a list of words
and outputs a single vector where that vector is of size
number of words in the vocab.
|
| Modifier and Type | Class and Description |
|---|---|
class |
PythonTransform
Row-wise Transform that applies arbitrary python code on each row
|
Copyright © 2020. All rights reserved.


CASTERBRIDGE ACADEMY
School allocation
| Funding | Description | Pupils | Rate | Total |
|---|---|---|---|---|
| Age Weighted Pupil Unit | Key Stage 3 | 481 | £3,758.00 | £1,807,598.00 |
| Key Stage 4 | 288 | £4,335.00 | £1,248,480.00 | |
| Deprivation | Secondary IDACI band F | 769 | £290.00 | £64,089.95 |
| Secondary IDACI band E | 769 | £380.00 | £59,659.93 | |
| Secondary FSM band F | 769 | £1,050.00 | £86,100.01 |
Age Weighted Pupil Unit
- Key Stage 3
- Pupils
- Rate
- Total
£120,359
- December 2015 to July 2016
- August 2016 to November 2016
- 12 months earning
£56,552
£76,335
- Baseline
- Affordability
- Calculated allocation
100%
£78,335
- Point one outcome
- Contract value to allocation value
-£1,867
Total


The NavigationManager contains all methods responsible for navigation.
More...
#include <navigation_manager.h>
|
| | NavigationManager (ros::NodeHandle &nh) |
| | Overloaded constructor that takes in a nodehandle. More...
|
| |
|
void | sendGoal () |
| | Method sending goals to the actionlib server.
|
| |
|
void | stopGoal () |
| | Method setting paused_ to true. Paused_ stops the navigation in sendGoal() method.
|
| |
| void | backOff (double back_velocity, double back_seconds) |
| | Method executing the back-off motion cue. More...
|
| |
| void | continueGoal (int seconds) |
| | Method Setting sendingGoal_ to true to continue the navigation. More...
|
| |
| void | setGoal1 (double x, double y, double z, double orientation) |
| | Method setting new coordinates to goal1_ variable. More...
|
| |
| void | setGoal2 (double x, double y, double z, double orientation) |
| | Method setting new coordinates to goal2_ variable. More...
|
| |
| void | setGoal3 (double x, double y, double z, double orientation) |
| | Method setting new coordinates to goal3_ variable. More...
|
| |
The NavigationManager contains all methods responsible for navigation.
The NavigationManager class manages the communication with the actionLib server and executes the motion cues. It is responsible to start, cancel and continue a navigation goal.
| lfe_navigation::NavigationManager::NavigationManager |
( |
ros::NodeHandle & |
nh | ) |
|
Overloaded constructor that takes in a nodehandle.
- Parameters
-
| nh | The nodehandle by which back-off backwards velocity is published for wheel control |
| void lfe_navigation::NavigationManager::backOff |
( |
double |
back_velocity, |
|
|
double |
back_seconds |
|
) |
| |
Method executing the back-off motion cue.
- Parameters
-
| back_velocity | Backwards velocity |
| back_seconds | Back-off duration in seconds |
| void lfe_navigation::NavigationManager::continueGoal |
( |
int |
seconds | ) |
|
Method Setting sendingGoal_ to true to continue the navigation.
- Parameters
-
| seconds | Time to wait before continuing the navigation in seconds |
| void lfe_navigation::NavigationManager::setGoal1 |
( |
double |
x, |
|
|
double |
y, |
|
|
double |
z, |
|
|
double |
orientation |
|
) |
| |
Method setting new coordinates to goal1_ variable.
- Parameters
-
| x | x-coordinate |
| y | y-coordinate |
| z | z-coordinate |
| orientation | Angular orientation around z-axis |
| void lfe_navigation::NavigationManager::setGoal2 |
( |
double |
x, |
|
|
double |
y, |
|
|
double |
z, |
|
|
double |
orientation |
|
) |
| |
Method setting new coordinates to goal2_ variable.
- Parameters
-
| x | x-coordinate |
| y | y-coordinate |
| z | z-coordinate |
| orientation | Angular orientation around z-axis |
| void lfe_navigation::NavigationManager::setGoal3 |
( |
double |
x, |
|
|
double |
y, |
|
|
double |
z, |
|
|
double |
orientation |
|
) |
| |
Method setting new coordinates to goal3_ variable.
- Parameters
-
| x | x-coordinate |
| y | y-coordinate |
| z | z-coordinate |
| orientation | Angular orientation around z-axis |
The documentation for this class was generated from the following file:


About Me
My name is Zachary Sadovszky. I'm a native Richmonder, I grew up in the West End and moved to the city when I was 18.
Upon my arrival into the adult world I was at a stalemate with what I wanted to do. I did the college thing for a little while and ultimately ended up working full time selling suits.
I found that job unfulfilling and wanted to change my course. I started teaching at a school for individuals on the Autism Spectrum. This job was rewarding, but the level of stress proved to be too much.
I transitioned to teaching neuro-typical children. I taughet pre-school, after-school, and after working a summer camp I realized that wasn't the field for me.
My best friend taught himself to code and got great job after great job with this skill. I saw an oppurtunity to make a career change and ultimately put me in the place I wanted to be financially.
I downloaded a few apps and with the help of my friend dipped my toes into the water, and found out it wasn't very cold. I really enjoyed the puzzles and solutions I was able to come up with.
With this new found hobby I decided to take a dive into the water and join the University of Richmond's Full Stack Bootcamp.
When I'm not in class or at work I love to skateboard with my friends and play music.


Eat together
There is something profoundly satisfying about sharing a meal. Eating together, breaking bread together, is one of the oldest and most fundamentaly unifying of human experiences.
When I was a young boy, my father told me never to recommend a church or a woman to anyone. And I have found it wise never to recommend a restuarant either. Something always goes wrong with the cheese souffle
There is something profoundly satisfying about sharing a meal. Eating together, breaking bread together, is one of the oldest and most fundamentaly unifying of human experiences.
There is something profoundly satisfying about sharing a meal.
There is something profoundly satisfying about sharing a meal.
There is something profoundly satisfying about sharing a meal.
There is something profoundly satisfying about sharing a meal.
There is something profoundly satisfying about sharing a meal.
There is something profoundly satisfying about sharing a meal.
There is something profoundly satisfying about sharing a meal. Eating together, breaking bread together, is one of the oldest and most fundamentaly unifying of human experiences.
There is something profoundly satisfying about sharing a meal. Eating together, breaking bread together, is one of the oldest and most fundamentaly unifying of human experiences.


We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty and the pursuit of Happiness.
If we find ourselves with a desire that nothing in this world can satisfy, the most probable explanation is that we were made for another world.
Tradition means giving votes to the most obscure of all classes, our ancestors. It is the democracy of the dead.


CLC-QuAD
CLC-QuAD[1] is the first large scale complex Chinese semantic parsing dataset over Wikidata, which consists of multi-hop questions, dualintent question, boolean questions and counting questions. This dataset is proposed to push forward Chinese KGQA research. In this dataset, questions are generated by translating all effective English questions in the LC-QuAD 2.0 dataset into Chinese. CLC-QuAD contains 28k+ pairs of question and SPARQL query in total, which is comparable to or bigger than most commonly used KBQA datasets.
Leaderboard
References
[1] Zou, Jianyun, Min Yang, Lichao Zhang, Yechen Xu, Qifan Pan, Fengqing Jiang, Ran Qin et al. A Chinese Multi-type Complex Questions Answering Dataset over Wikidata. arXiv preprint arXiv:2111.06086 (2021).


Does contain the classes and interfaces covering the data sample part as well as the service configuration data classes.


PIO configuration
Install VSCode
VS CODE is a more common development tool. Go to the VSCode official website and download and install the installation package for the corresponding operating system version.
Install the PIO plugin
Open VSCode -> click on the left extension -> search for PlatformIO -> click install plugin -> wait for the installation to complete -> restart VSCODE
Install the GD32V platform definition
PIO currently offers both command line and graphical interface installation. The following will introduce:
(PS: Recommended command line, because you can see the download progress bar.)
Command line
Click the PlatformIO logo on the left -> click New Terminal at the bottom left -> execute the following installation command in the terminal window
- Release version (stable version)
platformio platform install gd32v
- Development version (synchronized with Github)
platformio platform install https://github.com/sipeed/platform-gd32v
Note: Due to the domestic network environment, the installation process takes a long time, please be patient.
Graphical interface
Open VS CODE -> click on the PIO icon on the left -> click on the Open option at the bottom left -> click on the Platforms page -> click on Advanced Installation to open the add window
Enter the following URL in the window that opens
https://github.com/sipeed/platform-gd32v.git
Click Install to add it.
Wait patiently to install successfully. (The installation failure is mostly for network reasons, please try again after replacing the network environment)


|
||||||||||
| PREV CLASS NEXT CLASS | FRAMES NO FRAMES | |||||||||
| SUMMARY: NESTED | FIELD | CONSTR | METHOD | DETAIL: FIELD | CONSTR | METHOD |
public interface NativeEnhancer
The NativeEnhancer
is the interface used to perform enhancement tasks with
user defined native capable classes.
An enhanced class (on filesystem or enhanced on load) contains the complementary native information needed by the framework (native memory layout etc) to create and manage native instances.
If an enhanced class is used first time and loaded as usual, the class register itself into the framework.
JNIEasy.getEnhancer()
| Method Summary | |
|---|---|
java.lang.ClassLoader |
enableOnLoad(java.lang.String[] includeImports,
java.lang.String[] excludeImports)
Enables the runtime enhancement of user defined native capable classes using the default ClassLoader of the framework as parent. |
java.lang.ClassLoader |
enableOnLoad(java.lang.String[] includeImports,
java.lang.String[] excludeImports,
java.lang.ClassLoader parent)
Enables the runtime enhancement of user defined native capable classes. |
void |
enhance(java.net.URL filePath,
java.lang.String outputDir)
Enhances the user defined native capable classes specified in the XML file located with the filePath parameter. |
JNIEasy |
getJNIEasy()
Returns the JNIEasy parent object. |
| Method Detail |
|---|
JNIEasy getJNIEasy()
java.lang.ClassLoader enableOnLoad(java.lang.String[] includeImports, java.lang.String[] excludeImports, java.lang.ClassLoader parent)
ClassLoader
is created, registered with
com.innowhere.jnieasy.core.typedec.NativeTypeManager#setClassLoader(ClassLoader)
and returned,
this ClassLoader will be the default of the framework, and
NativeTypeManager.getClassLoader()
will return it.
The new ClassLoader is an enhancer ClassLoader:
if the class to load is a user defined native capable it will be enhanced
in memory previously to register in the JVM with ClassLoader.defineClass()
,
if the class is already
enhanced nothing will be done and will be registered normally.
This way, is not necessary a previous enhancement step, because is performed
on runtime automatically when the class is first time used.
To enhance a user native capable class on runtime, the ClassLoader needs
to locate the XML native information of the class, this archive is located using
ClassLoader.getResource(String)
(implies it must be in the classpath of the
parent ClassLoader) and must follow this name convention:
SimpleClassName.jnieasy.enh.xmlFor instance: if class name is
mypkg1.mypkg2.MyClass
, getResource()
is
invoked with the parameter: mypkg1/mypkg2/MyClass.jnieasy.enh.xml
, if found and valid the class
is enhanced.
The parent
parameter specifies the parent ClassLoader, the enhancer ClassLoader does not
follow a pure delegation model:
excludeImports
parameter.
includeImports
parameter
or is an internal native wrapper class.
Specifying what load by self first and what delegate after, is possible enhancing on runtime and running in any type of "class loading managed environment" because the enhancer ClassLoader does not need to be the root loader. But when using runtime enhancement, is necessary to load with the enhancer ClassLoader all classes that manipulate native classes, because if a normal class uses a native capable class and this has not been loaded before, then it will be loaded with the ClassLoader of the normal class, but if a native capable class not enhanced is loaded with the parent ClassLoader, then it never will be enhanced and never will be native. Achieve that is not very difficult: enable the enhancer before executing any native related code, and load the starting class explicitly with the enhancer ClassLoader.
For instance:
TheString[] included = new String[] { "myapp.nativemgrcode.*" }; ClassLoader enhancerCL = enhancer.enableOnLoad(included,null,myParentClassLoader); Class clsStart = Class.forName("myapp.nativemgrcode.Start",true, enhancerCL); // Start class implements StartInterface StartInterface start = (StartInterface)clsStart.newInstance(); start.run();
includeImports
and excludeImports
parameters are
String arrays with the "import formatted" criteria to include or exclude
(delegate) the class loading. The import format is explained in
NativeTypeManager.setDefaultImports(String[])
.
The enhancer ClassLoader implements the interface NativeEnhancerClassLoader
to
identification purposes.
includeImports
- the included list of classes using Java import syntaxexcludeImports
- the excluded list of classes using Java import syntax. Can be nullparent
- the parent ClassLoader
NativeTypeManager.getClassLoader()
java.lang.ClassLoader enableOnLoad(java.lang.String[] includeImports, java.lang.String[] excludeImports)
ClassLoader parent = getJNIEasy().getTypeManager().getClassLoader(); return enableOnLoad(includeImports,excludeImports,parent);
includeImports
- the included list of classes using Java import syntaxexcludeImports
- the excluded list of classes using Java import syntax, can be null
enableOnLoad(String[],String[],ClassLoader)
void enhance(java.net.URL filePath, java.lang.String outputDir)
filePath
parameter.
The XML file is a XML enhancement descriptor.
The resulting classes will be saved in the directory specified with the
outputDir
parameter, using the equivalent relative directory tree
of the package of each class to save.
For instance, if MyClass.class is enhanced and represents mypkg1.mypkg2.MyClass, then
the enhanced .class is saved as file:
outputDir + "/" + "mypkg1/mypkg2/MyClass.class"
The default ClassLoader as returned by NativeTypeManager.getClassLoader()
will be used to locate class files, is not necessary an enhancer ClassLoader.
Enhanced class files do not need XML descriptors anymore to create native objects.
filePath
- the location of XML file listing the classes to enhanceoutputDir
- the directory to save enhanced files
|
||||||||||
| PREV CLASS NEXT CLASS | FRAMES NO FRAMES | |||||||||
| SUMMARY: NESTED | FIELD | CONSTR | METHOD | DETAIL: FIELD | CONSTR | METHOD |


Create a new Engine instance.
The standard method of specifying the engine is via URL as the first positional argument, to indicate the appropriate database dialect and connection arguments, with additional keyword arguments sent as options to the dialect and resulting Engine.
The URL is a string in the form dialect://user:password@host/dbname[?key=value..], where dialect is a name such as mysql, oracle, postgres, etc. Alternatively, the URL can be an instance of URL.
**kwargs takes a wide variety of options which are routed towards their appropriate components. Arguments may be specific to the Engine, the underlying Dialect, as well as the Pool. Specific dialects also accept keyword arguments that are unique to that dialect. Here, we describe the parameters that are common to most create_engine() usage.
| Parameters: |
|
|---|
Create a new Engine instance using a configuration dictionary.
The dictionary is typically produced from a config file where keys are prefixed, such as sqlalchemy.url, sqlalchemy.echo, etc. The ‘prefix’ argument indicates the prefix to be searched for.
A select set of keyword arguments will be “coerced” to their expected type based on string values. In a future release, this functionality will be expanded and include dialect-specific arguments.
Represent the components of a URL used to connect to a database.
This object is suitable to be passed directly to a create_engine() call. The fields of the URL are parsed from a string by the module-level make_url() function. the string format of the URL is an RFC-1738-style string.
All initialization parameters are available as public attributes.
| Parameters: |
|
|---|
Translate url attributes into a dictionary of connection arguments.
Returns attributes of this url (host, database, username, password, port) as a plain dictionary. The attribute names are used as the keys by default. Unset or false attributes are omitted from the final dictionary.
| Parameters: |
|
|---|
Connects a Pool and Dialect together to provide a source of database connectivity and behavior.
Return a Connection object which may be newly allocated, or may be part of some ongoing context.
This Connection is meant to be used by the various “auto-connecting” operations.
When True, enable log output for this element.
This has the effect of setting the Python logging level for the namespace of this element’s class and object reference. A value of boolean True indicates that the loglevel logging.INFO will be set for the logger, whereas the string value debug will set the loglevel to logging.DEBUG.
Return a list of all table names available in the database.
Execute the given function within a transaction boundary.
This is a shortcut for explicitly calling begin() and commit() and optionally rollback() when exceptions are raised. The given *args and **kwargs will be passed to the function, as well as the Connection used in the transaction.
Provides high-level functionality for a wrapped DB-API connection.
Provides execution support for string-based SQL statements as well as ClauseElement, Compiled and DefaultGenerator objects. Provides a begin method to return Transaction objects.
The Connection object is not thread-safe.
Construct a new Connection.
Connection objects are typically constructed by an Engine, see the connect() and contextual_connect() methods of Engine.
Begin a transaction and return a Transaction handle.
Repeated calls to begin on the same Connection will create a lightweight, emulated nested transaction. Only the outermost transaction may commit. Calls to commit on inner transactions are ignored. Any transaction in the hierarchy may rollback, however.
Begin a nested transaction and return a Transaction handle.
Nested transactions require SAVEPOINT support in the underlying database. Any transaction in the hierarchy may commit and rollback, however the outermost transaction still controls the overall commit or rollback of the transaction of a whole.
Begin a two-phase or XA transaction and return a Transaction handle.
Returns self.
This Connectable interface method returns self, allowing Connections to be used interchangably with Engines in most situations that require a bind.
Returns self.
This Connectable interface method returns self, allowing Connections to be used interchangably with Engines in most situations that require a bind.
Detach the underlying DB-API connection from its connection pool.
This Connection instance will remain useable. When closed, the DB-API connection will be literally closed and not returned to its pool. The pool will typically lazily create a new connection to replace the detached connection.
This method can be used to insulate the rest of an application from a modified state on a connection (such as a transaction isolation level or similar). Also see PoolListener for a mechanism to modify connection state when connections leave and return to their connection pool.
Invalidate the underlying DBAPI connection associated with this Connection.
The underlying DB-API connection is literally closed (if possible), and is discarded. Its source connection pool will typically lazily create a new connection to replace it.
Upon the next usage, this Connection will attempt to reconnect to the pool with a new connection.
Transactions in progress remain in an “opened” state (even though the actual transaction is gone); these must be explicitly rolled back before a reconnect on this Connection can proceed. This is to prevent applications from accidentally continuing their transactional operations in a non-transactional state.
Executes and returns the first column of the first row.
The underlying result/cursor is closed after execution.
Interface for an object which supports execution of SQL constructs.
The two implementations of Connectable are Connection and Engine.
Wraps a DB-API cursor object to provide easier access to row columns.
Individual columns may be accessed by their integer position, case-insensitive column name, or by schema.Column object. e.g.:
row = fetchone()
col1 = row[0] # access via integer position
col2 = row['col2'] # access via name
col3 = row[mytable.c.mycol] # access via Column object.
ResultProxy also contains a map of TypeEngine objects and will invoke the appropriate result_processor() method before returning columns, as well as the ExecutionContext corresponding to the statement execution. It provides several methods for which to obtain information from the underlying ExecutionContext.
Close this ResultProxy.
Closes the underlying DBAPI cursor corresponding to the execution.
If this ResultProxy was generated from an implicit execution, the underlying Connection will also be closed (returns the underlying DBAPI connection to the connection pool.)
This method is called automatically when:
- all result rows are exhausted using the fetchXXX() methods.
- cursor.description is None.
Return last_inserted_ids() from the underlying ExecutionContext.
See ExecutionContext for details.
Return last_inserted_params() from the underlying ExecutionContext.
See ExecutionContext for details.
Return last_updated_params() from the underlying ExecutionContext.
See ExecutionContext for details.
Return lastrow_has_defaults() from the underlying ExecutionContext.
See ExecutionContext for details.
Return postfetch_cols() from the underlying ExecutionContext.
See ExecutionContext for details.
Proxy a single cursor row for a parent ResultProxy.
Mostly follows “ordered dictionary” behavior, mapping result values to the string-based column name, the integer position of the result in the row, as well as Column instances which can be mapped to the original Columns that produced this result set (for results that correspond to constructed SQL expressions).
Represent a Transaction in progress.
The Transaction object is not threadsafe.
Close this transaction.
If this transaction is the base transaction in a begin/commit nesting, the transaction will rollback(). Otherwise, the method returns.
This is used to cancel a Transaction without affecting the scope of an enclosing transaction.
Decorator, memoize a function in a connection.info stash.
Only applicable to functions which take no arguments other than a connection. The memo will be stored in connection.info[key].
Define the behavior of a specific database and DB-API combination.
Any aspect of metadata definition, SQL query generation, execution, result-set handling, or anything else which varies between databases is defined under the general category of the Dialect. The Dialect acts as a factory for other database-specific object implementations including ExecutionContext, Compiled, DefaultGenerator, and TypeEngine.
All Dialects implement the following attributes:
A mapping of DB-API type objects present in this Dialect’s DB-API implmentation mapped to TypeEngine implementations used by the dialect.
This is used to apply types to result sets based on the DB-API types present in cursor.description; it only takes effect for result sets against textual statements where no explicit typemap was present.
Build DB-API compatible connection arguments.
Given a URL object, returns a tuple consisting of a *args/**kwargs suitable to send directly to the dbapi’s connect function.
Create a two-phase transaction ID.
This id will be passed to do_begin_twophase(), do_rollback_twophase(), do_commit_twophase(). Its format is unspecified.
Check the existence of a particular sequence in the database.
Given a Connection object and a string sequence_name, return True if the given sequence exists in the database, False otherwise.
Check the existence of a particular table in the database.
Given a Connection object and a string table_name, return True if the given table (possibly within the specified schema) exists in the database, False otherwise.
Load table description from the database.
Given a Connection and a Table object, reflect its columns and properties from the database. If include_columns (a list or set) is specified, limit the autoload to the given column names.
Transform a generic type to a database-specific type.
Transforms the given TypeEngine instance from generic to database-specific.
Subclasses will usually use the adapt_type() method in the types module to make this job easy.
Bases: sqlalchemy.engine.base.Dialect
Default implementation of Dialect
Create a random two-phase transaction ID.
This id will be passed to do_begin_twophase(), do_rollback_twophase(), do_commit_twophase(). Its format is unspecified.
Provide a database-specific TypeEngine object, given the generic object which comes from the types module.
Subclasses will usually use the adapt_type() method in the types module to make this job easy.
Bases: sqlalchemy.engine.base.ExecutionContext
Bases: sqlalchemy.schema.SchemaVisitor
A visitor which accepts ColumnDefault objects, produces the dialect-specific SQL corresponding to their execution, and executes the SQL, returning the result value.
DefaultRunners are used internally by Engines and Dialects. Specific database modules should provide their own subclasses of DefaultRunner to allow database-specific behavior.
A messenger object for a Dialect that corresponds to a single execution.
ExecutionContext should have these datamembers:
Return a new cursor generated from this ExecutionContext’s connection.
Some dialects may wish to change the behavior of connection.cursor(), such as postgres which may return a PG “server side” cursor.
Return the list of the primary key values for the last insert statement executed.
This does not apply to straight textual clauses; only to sql.Insert objects compiled against a schema.Table object. The order of items in the list is the same as that of the Table’s ‘primary_key’ attribute.
Return a dictionary of the full parameter dictionary for the last compiled INSERT statement.
Includes any ColumnDefaults or Sequences that were pre-executed.
Return a dictionary of the full parameter dictionary for the last compiled UPDATE statement.
Includes any ColumnDefaults that were pre-executed.
Called after the execution of a compiled statement.
If a compiled statement was passed to this ExecutionContext, the last_insert_ids, last_inserted_params, etc. datamembers should be available after this method completes.
Called before an execution of a compiled statement.
If a compiled statement was passed to this ExecutionContext, the statement and parameters datamembers must be initialized after this statement is complete.
Return a result object corresponding to this ExecutionContext.
Returns a ResultProxy.
Bases: sqlalchemy.schema.SchemaVisitor
A visitor that can gather text into a buffer and execute the contents of the buffer.


Disable feature by name You can disable feature one by one, for more information go Here!
You can disable feature one by one, for more information go Here!
Personal token
If you're a Gitlab Enterprise user, visit your Gitlab Enterprise site, right-click on Refined Gitlab's icon in the toolbar and select Enable Refined Gitlab on this domain.


|
|
Meridian Point : UB-1
Location: In a depression, .1 cun above the inner canthus of the eye.
English Name: Bright Eyes
Pinyin Name: Jing Ming
Actions & Effect:
Main point for all eye disorders especially from wind (internal or external), excess, a/or heat.
Eye pain, strain, redness, swelling, itching, twitching, blurry vision, etc.
Myopia, color blindness, night blindness.
Glaucoma, optic nerve atrophy, cataracts.
Disease
Blurred vision, dizziness, nearsightness, night blindness, color blindness
Meridian Point : UB-2
Location: On the medial end of the eyebrow, directly above the inner canthus of the eye (on the supraorbital notch).
English Name: Bamboo Gathering
Pinyin Name: Zan Zhu
Actions & Effect:
Local point for sinus congestion a/or headache.
Red, itchy, watery eyes - allergies.
Use in facial massage for headaches with GB 20, ST 8, LI 4, and UB 60.
Glaucoma, night blindness, blurry and/or weak vision.
Generally, needle towards UB 1 for eye disease or Yuyao for supraorbital pain.
Disease
Facial distortion, blurred vision, redness, swelling and pain of the eye, twitching of eyelids, prolapse of eyelids, headache
Meridian Point : UB-3
Location: .5 cun inside the anterior hairline, directly above UB 2, between GV 24 and UB 4.
English Name: Eyebrow Ascension
Pinyin Name: Mei Chong
Actions & Effect:
Local point for headaches, nasal obstruction.
Epilepsy, agitation of the heart (possibly resulting in mania or excessive giddiness).
Disease
Headache, vertigo, nasal congestion
Meridian Point : UB-4
Location: 1.5 cun lateral to GV 24, or .5 cun inside the AHL at the junction of the medial 1/3 and lateral 2/3's distance between GV 24 & ST 8.
English Name: Deviating Turn
Pinyin Name: Qu Cha
Actions & Effect:
Local point for headache and/or nasal issues.
Headaches, particularly frontal/sinus, eye pain, vision issues (dimness, blurry).
Nasal polyps, nosebleeds, allergies, rhinitis.
Disease
Headache, nasal congestion, epistaxis, blurring of vision
Meridian Point : UB-5
Location: .5 cun behind UB 4 or 1 cun above the AHL and 1.5 cun lateral to the AML or 1.5 cun lateral to GV 23.
English Name: Fifth Place
Pinyin Name: Wu Chu
Actions & Effect:
Local point for headache and/or eye pain.
Epilepsy, yang ascension issues (manic episodes, dizziness, etc.)
Sinus congestion, stuffy head.
Disease
Headache, dizziness
Meridian Point : UB-6
Location: 1.5 cun posterior to UB 5 or 2.5 cun above AHL and 1.5 cun lateral to the AML.
English Name: Light Guard
Pinyin Name: Cheng Guang
Actions & Effect:
Local Point.
Disease
Blurring of vision, dizziness
Meridian Point : UB-7
Location: 1.5 cun posterior to UB 6 or 4 cun above the AHL and 1.5 cun lateral to the AML.
English Name: Celestial Connection
Pinyin Name: Tong Tian
Actions & Effect:
Local Point.
Disease
Nasal congestion, nasal polyps, nasal ulcers, rhinorrhea, epistaxis, headache, dizziness
Meridian Point : UB-8
Location: 1.5 cun posterior to UB 7 or 5.5 cun above the AHL and 1.5 cun lateral to the AML.
English Name: Declining Connection
Pinyin Name: Luo Que
Actions & Effect:
Useful for removing obstructions causing Qi flow issues to the head/brain (heavy head, vertex pain, distention, depression)
Disease
Blurring of vision, tinnitus
Meridian Point : UB-9
Location: 1.3 cun lateral to GV 17 or 2.5 cun above the PHL, 1.3 cun lateral to the PML in depression level with GV 17.
English Name: Jade Pillow
Pinyin Name: Yu Zhen
Actions & Effect:
Local Point.
Tong Ren/Tam Healing System: Used to effect the cerebellum (muscle coordination, equilibrium). Useful for stroke recovery, ALS, MS, Parkinson's, etc.
Disease
Headache and neck pain, blurring of vision, nasal congestion
Meridian Point : UB-10
Location: 1.3 cun lateral to GV 15 in a depression or .5 cun above the PHL and 1.3 cun lateral to the PML on the lateral aspect of the trapezius.
English Name: Celestial Pillar
Pinyin Name: Tian Zhu
Actions & Effect:
Neck issues, stiffness, ROM, occipital headache. For stiffness on one-side of the neck combine with SI 3 on the same side & GB 39 on the opposite side.
Secondary point to release the exterior in wind-cold conditions, primary is GB 20.
Disease
Headache, stiff neck, dizziness, headache, pain in the shoulder and back, depressive psychosis, epilepsy
Meridian Point : UB-11
Location: 1.5 cun lateral to GV 13, level with T1.
English Name: Great Shuttle
Pinyin Name: Da Zhu
Actions & Effect:
Wind disorders.
Hui-meeting point of the bones, useful with any bone or problem such as osteoporosis, arthritis, inflammation, sensation of heat in the bones, etc.
Useful adjunctive point to effect the lungs in cases of infections, colds a/or flus or asthma related conditions.
Sea of Blood Point with ST 37 & ST 39. According to the Ling Shu Treatise on the Seas, "when the Sea of blood is full, the patient has the sensation that his body is bigger than it is. One feels uneasy, and does not know the disease; when the Sea of blood is insufficient, one often feels the body is small, one feels uneasy and does not know the disease." May be useful for leukemia, anemia, said to tonify the bone marrow.
Disease
Stiff neck, pain in the shoulder and back, headache, nasal obstruction, sore throat, cough and fever
Meridian Point : UB-12
Location: 1.5 cun lateral to GV line, level with T2.
English Name: Wind Gate
Pinyin Name: Feng Men
Actions & Effect:
Main point to expel wind from the Wei Qi level of the body, useful for early stages of wind-cold conditions.
Apply moxa here and on ST 36 to strengthen the Wei Qi.
Disease
Common cold, cough, fever, headache, neck stiffness, pain in the chest and back
Meridian Point : UB-13
Location: 1.5 cun lateral to GV 12, level with T3.
English Name: Lung Shu
Pinyin Name: Fei Shu
Actions & Effect:
Main point for all Lung problems: cough, asthma, bronchitis, sore throat, nasal congestion, shortness of breath, weakness of the voice, etc.
Useful for skin disorders, itching, acne, hives, etc.
Lung related emotional imbalances such as grief and sadness.
Disease
Fever, cough, hemoptysis, night sweating, nasal congestion
Meridian Point : UB-14
Location: 1.5 cun lateral to the GV line, level with T4.
English Name: Jue Yin Shu (Pericardium Shu)
Pinyin Name: Jue Yin Shu
Actions & Effect:
For all heart conditions: palpitations, anxiety, stress, etc. Combine with PC 6 to open the chest.
As the "Jueyin Shu" you may also treat LV related conditions such as stagnation of LV Qi.
Disease
Angina pectoris, palpitation, vomiting, cough, chest congestion
Meridian Point : UB-15
Location: 1.5 cun lateral to GV 11, level with T5.
English Name: Heart Shu
Pinyin Name: Xin Shu
Actions & Effect:
Main point for all heart, blood and circulatory related issues of an excess or deficient nature.
Main point for all heart related emotional issues: palpitations, anxiety, stress, poor memory. Useful with PC 6, HT 7, CV 14 a/or UB 14.
Main point for insomnia.
Night sweats in Heart Qi a/or Yin deficiency.
Disease
Angina pectoris, palpitation, chest congestion, shortness of breath, insomnia, cough and night sweating
Meridian Point : UB-16
Location: 1.5 cun lateral to GV 10, level with T6.
English Name: Governing Shu
Pinyin Name: Du Shu
Actions & Effect:
Hot a/or toxic skin conditions (esp. on the back): acne, boils, etc.
Disease
Angina pectoris, chest congestion, gastric pain, abdominal pain, cough, asthma
Meridian Point : UB-17
Location: 1.5 cun lateral to GV 9, level with T7.
English Name: Diaphragm Shu
Pinyin Name: Ge Shu
Actions & Effect:
Hui-meeting Point of the Blood, useful for all Blood related conditions. Classically combined with UB 19 to create the "Four Flowers" which is used to nourish the Blood, although in clinical practice UB 18 & UB 19 may used equally as often.
For menstrual problems, from deficiency (scanty, light periods, amenorrhea) or stasis (dark clots, dysmenorrhea).
Important point for red, itchy skin disorders, from heat in the Blood: eczema, carbuncles.
As the "Diaphgram shu" it is useful for problems with diaphragmatic breathing or shortness of breath and other diaphragm related conditions such as belching or hiatal hernia.
Disease
Vomiting, Acute epigastric pain, hiccup, dysphagia, blood in the stools, cough, asthma
Meridian Point : UB-18
Location: 1.5 cun lateral to GV 8, level with T9.
English Name: Liver Shu
Pinyin Name: Gan Shu
Actions & Effect:
Main point for all Liver related conditions: hepatitis, jaundice, cirrhosis, Blood stagnation, Qi stagnation, etc.
Main point for eye problems, pain, itching, dryness, redness, blurred vision, visual dizziness, twitching.
Main point for LV related emotional issues such as anger, depression, irritability, frustration, stress a/or PMS.
Useful for hypochondriac a/or subcostal pain/distention.
Disease
Jaundice, dizziness, eye diseases, vomiting, back pain, epilepsy
Meridian Point : UB-19
Location: 1.5 cun lateral to GV 7, level with T10
English Name: Gallbladder Shu
Pinyin Name: Dan Shu
Actions & Effect:
Shao Yang level diseases, alternating fever and chills.
Main point for damp heat in the Liver and Gall Bladder: hepatitis, cholecystitis, jaundice, vomiting, flank pain and distension, bitter taste in the mouth. Often combined with the LV Shu (UB 18).
UB 17 & UB 19 are classcially known as the "Four Flowers," useful for tonifying the Blood.
Pain along the GB meridian (sides of the body) from any etiology, intercostal neuralgia, rib pain, trauma, herpes zoster.
Gall Bladder related emotional issues: indecision, timidity.
Disease
Jaundice, bitter taste in mouth, fever
Meridian Point : UB-20
Location: 1.5 cun lateral to GV 6, level with T11.
English Name: Spleen Shu
Pinyin Name: Pi Shu
Actions & Effect:
Main point for all Spleen problems: low energy, fatigue, prolapses, damp related conditions a/or bleeding disorders.
Commonly used for SP Qi Deficiency: fatigue, lack of appetite, abdominal bloating a/or distention, undigested food in the stools, chronic diarrhea a/or belching.
Disease
Abdominal distention, jaundice, vomiting, diarrhea, dysentery, blood in the stools
Meridian Point : UB-21
Location: 1.5 cun lateral to GV line, level with T12
English Name: Stomach Shu
Pinyin Name: Wei Shu
Actions & Effect & Functions:
Main point for all Stomach related issues: food stagnation, abdominal distention, borborygmus, mouth ulcers, vomiting, belching, nausea, etc.
Dissolve accumulations/lumps in the abdomen, combine with Pigen (point for lumps, tumors), 3.5 cun lateral to the lower border of L1.
Harmonizes the Stomach and strengthens the Spleen
Disease
Vomiting, abdominal distention, pain in the chest and back
Meridian Point : UB-22
Location: 1.5 cun lateral to GV 5, level with L1.
English Name: Triple Burner Shu
Pinyin Name: San Jiao Shu
Actions & Effect:
As Triple Heater Shu this point effects conditions related to imbalances between the upper and lower parts of the body especially those related to water: edema, bloating, ascites, borborygmus, difficult or painful urination, urinary retention.
Disease
Abdominal distention, vomiting, diarrhea, dysentery, stiffness and pain in the loins and back
Meridian Point : UB-23
Location: 1.5 cun lateral to GV 4, level with L2.
English Name: Kidney Shu
Pinyin Name: Shen Shu
Actions & Effect:
For all Kidney related issues which effect the brain, bone, hair, teeth a/or hearing.

Female sexual and reproductive disorders: dysmenorrhea, amenorrhea, cold uterus, frigidity, infertility, leukorrhea.
Tonification point in deficiency conditions: exhaustion, weakness, chronic fatique, good point for the elderly as Kidney Jing is naturally depleted.
Main point for acute or chronic low back pain, sprains a/or strains.
Useful for KD related ear issues: tinnitus, deafness, chronic ear infections.
Disease
Lower back pain, deafness, tinnitus, cough, asthma
Meridian Point : UB-24
Location: 1.5 cun lateral to GV line, level with L3.
English Name: Sea of Qi Shu
Pinyin Name: Qi Hai Shu
Actions & Effect:
Back pain.
Disease
Abdominal distention, hemorrhoids
Meridian Point : UB-25
Location: 1.5 cun lateral to GV 3, level with L4.
English Name: Large Intestine Shu
Pinyin Name: Da Chang Shu
Actions & Effect:
Main point for low back pain especially when related to constipation a/or menstruation. Combine with local points such as GV 3, UB 26, Shiqizhui (between L5 and S1), UB 31, UB 32, GB 30 & distal points such as GB 34, GB 39, GB 41, UB 40, UB 57, UB 58, UB 60 & UB 62.
Main point for all intestine related issues: constipation, diarrhea, dysentery, colitis, IBS, et.
Disease
Abdominal distention, diarrhea, constipation, bleeding hemorrhoids, lumbar pain
Meridian Point : UB-26
Location: 1.5 cun lateral to GV line, level with L5.
English Name: Origin Pass Shu
Pinyin Name: Guan Yuan Shu
Actions & Effect:
Low back pain.
Disease
Pain in the lumbosacral region, abdominal distention, diarrhea, frequent urination
Meridian Point : UB-27
Location: 1.5 cun lateral to GV line, level with 1st PSF.
English Name: Small Intestine Shu
Pinyin Name: Xiao Chang Shu
Actions & Effect:
Main point for all Small Intestine related issues: damp heat effecting the bladder (difficult or painful urination, hematuria, dark urine), damp heat effecting the intestines (diarrhea, dysentary).
Disease
Diarrhea, urinary problems, lower abdominal distention and pain
Meridian Point : UB-28
Location: 1.5 cun lateral to GV line, level with 2nd PSF.
English Name: Bladder Shu
Pinyin Name: Pang Guang Shu
Actions & Effect:
Main point for all Bladder issues: from damp heat (painful a/or dark urination), from cold (frequent urination, incontinence).
For dampness anywhere in the body, combine with SP 9 to expel dampness through urinatio.
Disease
Dysuria, retention of urine, stiffness and pain in loins and spine, leg pain, diarrhea, constipation
Meridian Point : UB-29
Location: 1.5 cun lateral to the GV line, level with the 3rd PSF.
English Name: Central Backbone Shu
Pinyin Name: Zhong Lu Shu
Actions & Effect:
Local Point.
Disease
Diarrhea, hernia, lower back pain and stiffness
Meridian Point : UB-30
Location: 1.5 cun lateral to the GV line, level with the 4th PSF.
English Name: White Ring Shu
Pinyin Name: Bai Huan Shu
Actions & Effect:
Secondary point for KD related gynecological disorders: menstrual problems, leukorrhea, pelvic inflammatory disease, enometriosi.
Disease
Irregular menstruation, hernia
Meridian Point : UB-31
Location: On the sacrum at the midpoint of the PSIS and the PML, level with the 1st PSF.
English Name: Upper Bone Hole
Pinyin Name: Shang Liao
Actions & Effect:
UB 31, UB 32, UB 33 & UB 34 together form the "Eight Liao" points and are all useful for local low back a/or sacrum problems and most genital and urinary related disorders. Of these UB 32 is most often used clinically.
Disease
Dysuria, impotence, irregular menstruation, prolapse of uterus
Meridian Point : UB-32
Location: On the sacrum medial and inferior to the PSIS, level with the 2nd PSF.
English Name: Second Bone Hole
Pinyin Name: Ci Liao
Actions & Effect:
UB 31, UB 32, UB 33 & UB 34 together form the "Eight Liao" points and are all useful for local low back a/or sacrum problems and most genital and urinary related disorders. Of these UB 32 is most often used clinically.
OB/GYN issues: leukorrhea, painful menstruation, blood stagnation.
Important point for easing labor pain a/or inducing labo.
Disease
Irregular menstruation, pain, weakness, and numbness of the lower extremities, hernia, dysuria, impotence
Meridian Point : UB-33
Location: On the sacrum medial and inferior to UB 32, level with the 3rd PSF.
English Name: Central Bone Hole
Pinyin Name: Zhong Liao
Actions & Effect:
UB 31, UB 32, UB 33 & UB 34 together form the "Eight Liao" points and are all useful for local low back a/or sacrum problems and most genital and urinary related disorders. Of these UB 32 is most often used clinicall.
Disease
Irregular menstruation, constipation, diarrhea, unsmooth urination
Meridian Point : UB-34
Location: On the sarcum lateral to GV 2, level with the 4th PSF.
English Name: Lower Bone Hole
Pinyin Name: Xia Liao
Actions & Effect:
UB 31, UB 32, UB 33 & UB 34 together form the "Eight Liao" points and are all useful for local low back a/or sacrum problems and most genital and urinary related disorders. Of these UB 32 is most often used clinicall.
Disease
Lower abdominal pain, constipation, unsmooth urination, irregular menstruation
Meridian Point : UB-35
Location: .5 cun lateral to the GV line on either side of the tip of the coccyx bone.
English Name: Meeting of Yang
Pinyin Name: Hui Yang
Actions & Effect:
Main point for hemorrhoids.
Trauma a/or pain of the coccyx, deviation.
Disease
Diarrhea, blood in the stools, hemorrhoids, impotence
Meridian Point : UB-36
Location: On posterior side of the thigh at the midpoint of the inferior gluteal crease (locate in prone position).
English Name: Support
Pinyin Name: Cheng Fu
Actions & Effect:
Low back pain/sciatica where pain runs down the posterior aspect of the leg.
Weakness of the lower limb.
Disease
Pain in the waist, hemorrhoids
Meridian Point : UB-37
Location: 6 cun below UB 36 on a line joining UB 36 and UB 40.
English Name: Gate of Abundance
Pinyin Name: Yin Men
Actions & Effect:
Local Point.
Disease
Lumbar pain, pain, numbness and weakness of the lower extremities
Meridian Point : UB-38
Location: 1 cun above UB 39 on the medial side of the tendon of biceps femoris (found with knee slightly bent).
English Name: Superficial Cleft
Pinyin Name: Fu Xi
Actions & Effect:
Local Point.
Disease
Stiffness and pain of waist and spine, lower abdominal distention, spasmodic pain in foot and legs
Meridian Point : UB-39
Location: Lateral to UB 40 on the medial border of the tendon of biceps femoris.
English Name: Bend Yang
Pinyin Name: Wei Yang
Actions & Effect:
Damp heat conditions effecting the lower warmer: disperse for difficult urination.
Tonify for urinary incontinence.
Disease
Lumbar pain, spasm and weakness of the lower extremities, abdominal pain, vomiting, diarrhea
Meridian Point : UB-40
Location: Midpoint of the transverse crease of the popliteal fossa, between the tendons of biceps femoris and semitendinosis.
English Name: Bend Middle
Pinyin Name: Wei Zhong
Actions & Effect:
As the Lumbar Command Point, useful for all lumbar related issues: acute low back pain, sprain, muscle spasms, etc.
Main point for heat conditions such as summer heat, heatstroke and heat exhaustion.
Main point for all skin related issues: itching, oozing, inflammation, etc.
Good local point for leg a/or knee pai.
Disease
Lumbar pain, spasm and weakness of the lower extremities, abdominal pain, vomiting, diarrhea
Meridian Point : UB-41
Location: 3 cun lateral to the GV line, level with T2, on the spinal border of the scapula.
English Name: Attached Branch
Pinyin Name: Fu Fen
Actions & Effect:
Local Point.
Disease
Rigidity and pain of the neck, spasm of the shoulder and back, numbness of the elbow and arm
Meridian Point : UB-42
Location: 3 cun lateral to GV 12, level with T3, on the spinal border of the scapula.
English Name: Po Door
Pinyin Name: Po Hu
Actions & Effect:
Reinforce the Lung Shu (UB 13) for Lung related disorders: cough, asthma, etc.
Effect the psycho-emotional aspects of the Lung meridian.
Drain heat from the Lun.
Disease
Cough, asthma, pulmonary tuberculosis, neck stiffness, pain in the shoulder and back
Meridian Point : UB-43
Location: 3 cun lateral to the GV line, level with T4.
English Name: Gao Huang Shu
Pinyin Name: Gao Huang Shu
Actions & Effect:
Main point for all disorders of the Lung and Upper Warmer: asthma, dyspnea, cough, tuberculosis, etc.
Tonification point for cases of weakness and deficiency especially from chronic illness.
Disease
Pulmonary tuberculosis, cough, asthma, poor appetite, loose stools, emaciation and weakness, aching pain in the shoulder and back
Meridian Point : UB-44
Location: 3 cun lateral to GV 11, level with T5.
English Name: Spirit Hall
Pinyin Name: Shen Tang
Actions & Effect:
Reinforce the HT Shu (UB 15) and treat Heart related psycho-emotional issues: anxiety, insomnia, etc.
Disease
Cardiac pain, palpitations, insomnia, chest congestion, cough, asthma
Meridian Point : UB-45
Location: 3 cun lateral to GV 10, level with T6.
English Name: Yi Xi
Pinyin Name: Yi Xi
Actions & Effect:
Local Point.
Disease
Cough, asthma, pain of the shoulder and back
Meridian Point : UB-46
Location: 3 cun lateral to GV 9, level with T7.
English Name: Diaphragm Pass
Pinyin Name: Ge Guan
Actions & Effect:
Local Point.
Disease
Vomiting, belching, hiccup, stiffness and pain of the back and spine
Meridian Point : UB-47
Location: 3 cun lateral to GV 8, level with T9.
English Name: Hun Gate
Pinyin Name: Hun Men
Actions & Effect:
Reinforce the LV Back Shu (UB 18) and help treat the psycho-emotional aspects of the LV: depression, frustration, etc.
Disease
Chest congestion and hypochondrium, vomiting, diarrhea, back pain
Meridian Point : UB-48
Location: 3 cun lateral to GV 7, level with T10.
English Name: Yang Headrope
Pinyin Name: Yang Gang
Actions & Effect:
Local Point.
Disease
Jaundice, abdominal pain, borborygmus, diarrhea, diabetes
Meridian Point : UB-49
Location: 3 cun lateral to GV 6, level with T11.
English Name: Reflection Abode
Pinyin Name: Yi She
Actions & Effect:
Reinforce the SP Shu (UB 20) especially with damp heat conditions: hepatitis, cholecystitis, wasting and thirsting (diabetes), etc.
Disease
Abdominal distention, borborygmus, vomiting, diarrhea
Meridian Point : UB-50
Location: 3 cun lateral to the GV line, level with T12.
English Name: Stomach Granary
Pinyin Name: Wei Cang
Actions & Effect:
Local Point.
Disease
Abdominal distention, infantile dyspepsia, edema
Meridian Point : UB-51
Location: 3 cun lateral to GV 5, level with L1.
English Name: Huang Gate
Pinyin Name: Huang Men
Actions & Effect:
Local Point.
Disease
Abdominal pain, constipation, abdominal mass, breast disease
Meridian Point : UB-52
Location: 3 cun lateral to GV 4, level with L2.
English Name: Will Chamber
Pinyin Name: Zhi Shi
Actions & Effect:
Reinforce the KD Back Shu (UB 23) for fertility issues (impotence, infertility) a/or urinary issues especially from damp heat or KD Qi or Yang deficiency (incontinence, dribbling urine).
Disease
Impotence, lumbar stiffness and pain
Meridian Point : UB-53
Location: 3 cun lateral to the medial sacral crest, level with the 2nd PSF.
English Name: Bladder Huang
Pinyin Name: Bao Huang
Actions & Effect:
Local Point.
Disease
Lumbar pain, abdominal distention
Meridian Point : UB-54
Location: 3 cun lateral to the GV line, level with the 4th PSF.
English Name: Sequential Limit
Pinyin Name: Zhi Bian
Actions & Effect:
Sciatica especially if pain radiates along the posterior aspect of the leg.
Five Lin (Painful Urination) disorder.
Disease
Dysuria, constipation, muscular atrophy, pain, numbness and motor impairment of the lower extremities, hemorrhoids
Meridian Point : UB-55
Location: 2 cun directly below UB 40 between the medial and lateral heads of the gastrocnemius, on a line joining UB 40 - UB 57.
English Name: Yang Union
Pinyin Name: He Yang
Actions & Effect:
Local Point.
Disease
Lumbar stiffness and pain, pain, numbness and weakness of the lower extremities, hernia
Meridian Point : UB-56
Location: 5 cun below UB 40 on the line connecting UB 40 - UB 57, midway between UB 55 and UB 57 in the center of the belly of the gastrocnemius.
English Name: Sinew Support
Pinyin Name: Cheng Jin
Actions & Effect:
Local Point.
Disease
Hemorrhoids
Meridian Point : UB-57
Location: 8 cun below UB 40 in a pointed depression below the gastrocnemius when leg is stretched or heel is lifted.
English Name: Mountain Support
Pinyin Name: Cheng Shan
Actions & Effect:
Main point for pain, swelling a/or cramping of the calf.
Heel a/or foot pain from trauma but also from paralysis a/or neurological disorder. Main point for hemorrhoids from any etiology.
Disease
Hemorrhoids
Meridian Point : UB-58
Location: 7 cun directly above UB 60 on the posterior border of the fibula about 1 cun lateral and inferior to UB 57.
English Name: Taking Flight
Pinyin Name: Fei Yang
Actions & Effect:
Releases the exterior for wind/wind-cold conditions, especially useful when accompanied with neck stiffness a/or occipital headache.
As Luo Connecting Point, which connects to the KD, useful for chronic low back pain, especially with weak lower limbs and KD deficiency.
"Excess above with deficiency below," weak low back w/tight stiff neck a/or low back pain with weak lower limb.
Disease
Headache, dizziness, pain and weakness of the lumbar and leg, hemorrhoids
Meridian Point : UB-59
Location: 3 cun directly above UB 60.
English Name: Instep Yang
Pinyin Name: Fu Yang
Actions & Effect:
Acute pain a/or spasm of the Bladder a/or Yang Qiao meridians.
Lateral ankle sprai.
Disease
Headache, heavy sensation of the head, pain, numbness and weakness of the lower extremities
Meridian Point : UB-60
Location: In a depression between the tip of the external malleolus and the achilles tendon.
English Name: Kunlun Mountains
Pinyin Name: Kun Lun
Actions & Effect:
Main point for pain anywhere along the spine (UB 40 may be used more for pain in the middle of the spine).
Main point for chronic low back pain a/or problems of pain a/or numbness in the lower limbs.
Main point for headache and other excesses effecting the head.
Induce labor or promote discharge of a retained placent.
Disease
Acute lumbar pain, swelling and pain of the heel, difficult labor, headache, neck stiffness, dizziness
Meridian Point : UB-61
Location: Posterior and Inferior to the external malleolus, directly below UB 60, lateral to the calcaneum at the junction of the red and white skin.
English Name: Subservient Visitor
Pinyin Name: Pu Can
Actions & Effect:
Local Point.
Disease
Pain, numbness and weakness of the lower extremities
Meridian Point : UB-62
Location: In a depression directly below the external malleolus.
English Name: Extending Vessel
Pinyin Name: Shen Mai
Actions & Effect:
With SI 3 for low back pain, difficulty walking, spinal problems as well as wind-cold effecting the taiyang channels: stiff neck a/or shoulders, occipital headache, etc.
Insomnia, nervousness (especially late at night), combine with KD 6.
Disease
Epilepsy, manic psychosis, insomnia, headache, neck rigidity, pain of the lumbar and leg
Meridian Point : UB-63
Location: On the lateral side of the foot, directly below the anterior border of the external malleolus, on the lower border of the cuboid bone.
English Name: Metal Gate
Pinyin Name: Metal Gate
Actions & Effect:
Local Point.
Disease
Headache, manic psychosis, epilepsy, infantile convulsion, lumbar pain, pain, numbness and weakness of the lower extremities, pain in the external malleolus
Meridian Point : UB-64
Location: Below the tuberosity of the 5th metatarsal bone at the junction of the red and white skin.
English Name: Capital Bone
Pinyin Name: Jing Gu
Actions & Effect:
Has a relationship to the Heart and Spirit, good distal point for palpitations, chest pain, irritability, mental confusion.
Local Point.
Disease
Headache, neck rigidity, cataract
Meridian Point : UB-65
Location: Posterior to the 5th metatarsophalangeal joint at the junction of the red and white skin.
English Name: Bundle Bone
Pinyin Name: Shu Gu
Actions & Effect:
Local Point.
Disease
Headache, neck rigidity, pain of the lumbar and the leg, dizziness
Meridian Point : UB-66
Location: Anterior to the 5th metatarsophalangeal joint
English Name: Valley Passage
Pinyin Name: Tong Gu
Actions & Effect:
Local Point.
Disease
Headache, neck rigidity, dizziness, psychosis
Meridian Point : UB-67
Location: .1 cun posterior to the corner of the nail on the lateral side of the little toe.
English Name: Reaching Yin
Pinyin Name: Zhi Yin
Actions & Effect:
Clears pain a/or stagnation from the opposite end of the channel: headache, eye pain, sinus pain, etc.
Use with moxabustion to adjust breech fetal position (generally indirect moxa for 10-20 minutes 1x/day).
Disease
Headache, eye pain, nasal congestion, difficult labor
|


Date created: {{ object.created|date:SYSTEM_SETTINGS.display_date_format }}
mdi-content-save-outlineSave
{% include "_includes/page_action_item.html" with click_action="isDisplayExpansionPanel = !isDisplayExpansionPanel" icon="[[ displayIcon ]]" tooltip="Change Display" %}
{% csrf_token %}
{% if form.errors %}
{% include "_includes/errors.html" %}
{% endif %}
mdi-contactsContact Details
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/autocomplete.html" %}
{% include "contacts/includes/other_online_id_table_edit.html" %}
mdi-accountPersonal
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textfield_date.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/select.html" %}
{% include "_includes/model_fields/autocomplete.html" %}
mdi-undoCurrent/Previous Work
{% include "_includes/model_fields/slider.html" %}
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textarea.html" %}
mdi-informationOthers
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/select.html" %}
{% include "_includes/model_fields/autocomplete.html" %}
mdi-medical-bagMedical
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textfield_date.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/select.html" %}
{% include "_includes/v_tab.html" %}
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/autocomplete.html" %}
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textfield_date.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/select.html" %}
{% include "_includes/model_fields/autocomplete.html" %}
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/select.html" %}
{% include "_includes/model_fields/autocomplete.html" %}
{% include "_includes/model_fields/slider.html" %}
{% include "_includes/model_fields/textfield.html" %}
{% include "_includes/model_fields/textfield_date.html" %}
{% include "_includes/model_fields/textarea.html" %}
{% include "_includes/model_fields/select.html" %}


Here at Mama's Pizza we are dedicated to satisfying our customers.We have competent workers who promptly respond to customers orders according to our policy Your request,our command.
Monday...........10am-3pm
Tuesday...........10am-3pm
Wednesday.....10am-3pm
Thursday........10am-3pm
Friday............10am-3pm
Weekend..............closed


Hosting your Blog on Amazon S3
July 25, 2013 · 4 minute read · CommentsOne of the cleanest designed blogs I have seen in a while belongs to Karma Mobility. So I asked in the comments on a particularly interesting post by Stefan Borsje and he very nicely responded “Thanks Daniel! This blog uses Jekyll and is hosted on S3.”
Hmmm. That’s two cool things at once.
So let’s do this! I know a little about Jekyll and I know it’s engine behind GitHub Pages, plus om Github you can host it for free.But it has two disadvantages I know of:
- You can not use custom Jekyll plugins with GitHub Pages. Your site is generated with
--safe
. - There is no possibility to redirect requests. This is vital if you do not want to lose any link traffic when fixing a typo in your URL.
Jekyll on Amazon S3
In order to serve your site from S3 you need to first create a bucket to hold the content. So, using the S3 web console create a bucket.
Next we need to setup the bucket for web hosting. Click the properties button to edit the properties of your new bucket. Then go to the Static Website Hosting section and click “Enabled website hosting”. Note the Endpoint of your site and remember to save!
You also need to set your index document. I chose index.html for my index document and nothing for my error document since I am using a redirect rule to redirect all errors back to the root of my blog. That way no one ever gets a 404. Cool right?
The rule is simple:
<RoutingRules>
<RoutingRule>
<Condition>
<HttpErrorCodeReturnedEquals>403</HttpErrorCodeReturnedEquals >
</Condition>
<Redirect>
<HostName>error.html</HostName>
</Redirect>
</RoutingRule>
</RoutingRules>
In the “Permissions” section you also need to add a bucket policy that makes your bucket content publicly available:
{
"Version": "2008-10-17",
"Statement": [
{
"Sid": "PublicReadForGetBucketObjects",
"Effect": "Allow",
"Principal": {
"AWS": "*"
},
"Action": "s3:GetObject",
"Resource": "arn:aws:s3:::snapvotr-blog/*"
}
]
}
Now you could click Upload next and push your site up on S3.
But we have another trick up our sleeve - s3_website
First if you are already running Jekyll then you should have all the dependencies already setup. So just run:
gem install s3_website
To configure s3_website, make sure you are in your website’s root directory, then run:
s3_website cfg create
This generates a configuration file called s3_website.yml
. Open it in a text editor and change the values to your AWS secret and key ID. This is where you also name your Amazon S3 bucket.  The command will also ask if you want to use Amazon’s CloudFront CDN. I said “y”.
In hindsight I would have kept it simple and made sure everything was working properly from S3 first. If you do enable it there are some additional steps you have to do on Amazon:
- You have to tell CloudFront what CNAME(s) you will be using. So Login, edit your new CloudFront distribution and fill in the “Alternate Domain Names (CNAMEs)” field. Since I was creating a blog I used “blog.website.com” with my own domain of course.
- You also need to tweak the origin per the link in the references - you need a custom origin* pointing to your S3 bucket.
Now, deploying your website is as simple as running:
s3_website push
When I am done adding content or tweaking I can build and deploy with two commands:
jekyll build
s3_website push
That my friends is AWESOME!
Setup your CNAME with your DNS provider
You must be able to point a CNAME at CloudFront. I was creating a blog so it was easy. You do this via your DNS provider, which in many cases is your domain registrar unless you already moved your DNS hosting elsewhere. I created a blog CNAME (so my URL will end up being blog.website.com) pointing to the Amazon CloudFront domain that was assigned. It looks like this: xxxxxxxxxxxx.cloudfront.net. Boom! done.
References
- http://docs.aws.amazon.com/AmazonS3/latest/dev/WebsiteHosting.html
- http://docs.aws.amazon.com/AmazonCloudFront/latest/DeveloperGuide/CNAMEs.html
- http://holgr.com/blog/2011/12/getting-a-custom-404-document-using-amazon-cloudfront-and-s3/
- http://legatomaniac.blogspot.com/2013/06/howto-avoid-403-in-cloudfront-requests.html


--- layout: post authors: ["Rayna Harris"] title: "Assessing Assessment" date: 2015-10-10 time: "02:30:00" tags: ["Assessment"] ---
Jason Williams and I met with two consultants at the University of Texas at the end of September to get feedback on Software Carpentry's post-workshop survey. They gave us detailed suggestions for improving six of the questions, and felt the rest were OK as they are. The feedback is given below; even without the whole questionnaire (which we will post shortly), we hope it's helpful.
Change "I learned valuable skills" to "I learned skills that I can use in my research" because valuable is too vague and subjective.
"The instructors/helpers were effective" is vague. Maybe add an "(e.g. knowledgeable, good communicators)" or make multiple specific questions.
There were a few suggestions/options for improving the question, "Before the workshop, did you feel any of the following topics were intimidating?"
Change to a sliding scale response to allow finer resolution between intimidating and not intimidating.
Change the response to a Likert scale and rephrase the question to something like, "For each topic, how well do you identify with the statement 'Before the workshop, this topic was very intimidating.'" Or, you could use a "describes my feelings" scale or agree-disagree scale.
Also, students may not be able to accurately self-report on pre-workshop attitude after taking the workshop. This question could be move to pre-assessment survey.
There were a few suggestions for, "After taking this workshop, which statement best reflects how you feel about learning more on the following subjects?"
Change questions to, "After taking the workshop, how interested are in you in learning more about the following topics?"
New responses could be something like 'uninterested/not relevant', 'uninterested/already know enough', 'slightly uninterested', 'neither uninterested nor interested', 'slightly interested', 'interested'.
For the second skills questions, we might be able to get at both what was covered in the workshop and what skills were gained by the student using the side-by-side question format. For example:
The question would be, "For the following tasks, please rate the quality of instruction and how confident you are in your ability to perform the task."
Scale for quality of instruction subset: poor-excellent or above-below average.
Scale for task performance subset: no chance to good chance or easy to difficult.
Change "sex" to "gender" for demographic questions.


Class rex_backend_password_policy
- rex_password_policy
- rex_backend_password_policy uses rex_factory_trait
Package: redaxo\core\login
Author: gharlan
Located at redaxo/src/core/lib/login/backend_password_policy.php
Author: gharlan
Located at redaxo/src/core/lib/login/backend_password_policy.php
Methods summary
public
|
||
public static
static
|
Methods inherited from rex_password_policy
check()
,
getRule()
,
isValid()
,
matchesCount()
Methods used from rex_factory_trait
callFactoryClass()
,
getFactoryClass()
,
hasFactoryClass()
,
setFactoryClass()


Random image1 downloaded from unsplash.com.
Random image2 downloaded from unsplash.com.
Random image3 downloaded from unsplash.com.
A true random image courtesy of unsplash.com.


Preparation time
less than 30 mins
Cooking time
10 to 30 mins
Serves
Serves 4
Season the John Dory fillets with salt and freshly ground black pepper, then dredge the fillets in the flour on each side.
Heat the oil a frying pan until hot. Add the fish, skin-side down and cook on each side for 1-2 minutes, until just cooked through. Remove from the pan and set aside to rest in a warm place.
For the shrimp sauce vierge, heat the olive oil in a separate frying pan over a very low heat. When the oil is warm (but not too hot), add the shallots and garlic and warm through for one minute.
Add the tomatoes and shrimps and warm through for a further two minutes.
Add the tarragon, lemon juice and season, to taste, with salt and freshly ground black pepper.
For the sautéed potatoes, heat a separate frying pan until hot then add the rapeseed oil and potatoes. Sauté for 5-6 minutes, until golden brown all over and tender. Remove with a slotted spoon and drain the potatoes onto kitchen paper. Season, to taste, with salt and sprinkle with the parsley.
To serve, place the John Dory onto the centre of the plate, then spoon over the shrimp sauce vierge. Place a spoonful of the sautéed potatoes alongside.


{% assign reading_time = content | strip_html | number_of_words | append: '.0' | divided_by: 180 %}
{% if reading_time < 0.5 %}
Less than a minute read
{% elsif reading_time >= 0.5 and reading_time < 1.5 %}
1 minute read
{% elsif reading_time >= 1.5 %}
{{ reading_time | round }} minutes read
{% endif %}


|
Apache Mesos
|
Classes | |
| class | ProcessCapabilities |
| Encapsulation of capability value sets. More... | |
| class | Capabilities |
| Provides wrapper for the linux process capabilities interface. More... | |
Enumerations | |
| enum | Capability : int { CHOWN = 0, DAC_OVERRIDE = 1, DAC_READ_SEARCH = 2, FOWNER = 3, FSETID = 4, KILL = 5, SETGID = 6, SETUID = 7, SETPCAP = 8, LINUX_IMMUTABLE = 9, NET_BIND_SERVICE = 10, NET_BROADCAST = 11, NET_ADMIN = 12, NET_RAW = 13, IPC_LOCK = 14, IPC_OWNER = 15, SYS_MODULE = 16, SYS_RAWIO = 17, SYS_CHROOT = 18, SYS_PTRACE = 19, SYS_PACCT = 20, SYS_ADMIN = 21, SYS_BOOT = 22, SYS_NICE = 23, SYS_RESOURCE = 24, SYS_TIME = 25, SYS_TTY_CONFIG = 26, MKNOD = 27, LEASE = 28, AUDIT_WRITE = 29, AUDIT_CONTROL = 30, SETFCAP = 31, MAC_OVERRIDE = 32, MAC_ADMIN = 33, SYSLOG = 34, WAKE_ALARM = 35, BLOCK_SUSPEND = 36, AUDIT_READ = 37, MAX_CAPABILITY = 38 } |
| enum | Type { EFFECTIVE, PERMITTED, INHERITABLE, BOUNDING } |
Functions | |
| Capability | convert (const CapabilityInfo::Capability &capability) |
| std::set< Capability > | convert (const CapabilityInfo &capabilityInfo) |
| CapabilityInfo | convert (const std::set< Capability > &capabilitySet) |
| std::ostream & | operator<< (std::ostream &stream, const Capability &capability) |
| std::ostream & | operator<< (std::ostream &stream, const Type &type) |
| std::ostream & | operator<< (std::ostream &stream, const ProcessCapabilities &capabilities) |
| enum mesos::internal::capabilities::Capability : int |
| Capability mesos::internal::capabilities::convert | ( | const CapabilityInfo::Capability & | capability | ) |
| std::set<Capability> mesos::internal::capabilities::convert | ( | const CapabilityInfo & | capabilityInfo | ) |
| CapabilityInfo mesos::internal::capabilities::convert | ( | const std::set< Capability > & | capabilitySet | ) |
| std::ostream& mesos::internal::capabilities::operator<< | ( | std::ostream & | stream, |
| const Capability & | capability | ||
| ) |
| std::ostream& mesos::internal::capabilities::operator<< | ( | std::ostream & | stream, |
| const Type & | type | ||
| ) |
| std::ostream& mesos::internal::capabilities::operator<< | ( | std::ostream & | stream, |
| const ProcessCapabilities & | capabilities | ||
| ) |


Fortnite
Epic Games
GET
Information
Fortnite sideloaded after it got banned
Updated
June 15, 2020
License
Free Package


[§342D-17] Enforcement by state and county authorities. All state and county health authorities and police officers shall enforce this chapter and the rules and orders of the department. [L 1989, c 212, pt of §2]
Law Journals and Reviews
Ala Loop and the Private Right of Action Under Hawaii Constitution Article XI, Section 9: Charting a Path Toward a Cohesive Enforcement Scheme. 33 UH L. Rev. 367 (2010).


Click "Start Indexing" button to refresh draw.io diagrams index Please note that the indexing procedure will take some time and the browser window must remain open until the indexing is completed.
Gliffy import
Click "Start Import" button to import all Gliffy diagrams to draw.io Please note that the import procedure will take some time and the browser window must remain open until the import is completed.


See the repository README for explanations and page source code for an example on how to use the BiquadFilter.


class NetworkRequestHelper
Does the HTTP GET request to the backend. Uses EventBus to communicate back to the SDK user
timeout
- set the connection timeout in ms
<init> |
Does the HTTP GET request to the backend. Uses EventBus to communicate back to the SDK user NetworkRequestHelper(timeout: Long) |
doHttpGetRequestAsync |
Does a request to the backend. Will communicate back over EventBus to the SDK user. fun doHttpGetRequestAsync(request: NetworkRequest): Unit |