| Supplemental
Table 6: Canonical and metabolic signaling pathayws - 120 hpf |
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Ingenuity pathway analysis results for 120 hpf for
all 2DLCMSMS and 2DGE identifications |
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Identifications for 2D LCMSMS and 2D PAGE at 120
hpf are listed from searches against the IPI Danio rerio v3.07 database |
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As the Ingenuity Pathway analyis did not support
zebrafish IPI accession numbers as inputs, a BLAST search of the identified
IPI sequences against the human Refseq database was performed. |
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To fulfill this criteria we performed a blast search
for all the IPI accession sequences against the Human Refseq Database, theses
accession numbers were used to generated |
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Theses accession numbers were used to generated the
pathway associations for canonical and metabolic signaling. |
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| 120 hpf |
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| method |
pathway category |
pathway |
accession (IPI) |
accession (RefSeq) |
gene symbol |
description |
location |
gene family |
interacting drugs |
additional pathway members (n in dataset / k in
database) |
|
| Filter |
Filter |
Filter |
Filter |
Filter |
Filter |
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| 2D LCMSMS |
canonical signaling |
amyloid processing |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
amyloid processing |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
2_35 |
|
| 2D LCMSMS |
canonical signaling |
Antigen presentation pathway |
IPI00503338 |
NP_001019820 |
CANX |
calnexin |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Antigen presentation pathway |
IPI00481873 |
NP_004334 |
CALR |
calreticulin |
Nucleus |
transcription regulator |
|
3_42 |
|
| 2D LCMSMS |
canonical signaling |
Antigen presentation pathway |
IPI00614458 |
NP_035316 |
PSMB5 |
proteasome (prosome, macropain) subunit, beta type, 5 |
Cytoplasm |
peptidase |
bortezomib |
|
|
| 2D LCMSMS |
canonical signaling |
apoptosis signaling |
IPI00490244 |
NP_003118 |
SPTAN1 |
spectrin, alpha, non-erythrocytic 1 (alpha-fodrin) |
Plasma Membrane |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
apoptosis signaling |
IPI00483990 |
NP_031834 |
CYCS |
cytochrome c, somatic |
Cytoplasm |
enzyme |
|
2_68 |
|
| 2D LCMSMS |
canonical signaling |
B cell receptor signaling |
IPI00492706 |
NP_002863 |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small
GTP binding protein Rac2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
B cell receptor signaling |
IPI00486393 |
NP_032939 |
PPP3CA |
protein phosphatase 3 (formerly 2B), catalytic subunit, alpha
isoform (calcineurin A alpha) |
Cytoplasm |
phosphatase |
cyclosporin A, pimecrolimus,
tacrolimus |
2_115 |
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00509545 |
NP_001002841 |
MYL4 |
myosin, light polypeptide 4, alkali; atrial, embryonic |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00487399 |
NP_001010935 |
RAP1A |
RAP1A, member of RAS oncogene family |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00508152 |
NP_001018005 |
TPM1 |
tropomyosin 1 (alpha) |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00506741 |
NP_001222 |
CASQ1 |
calsequestrin 1 (fast-twitch, skeletal muscle) |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00488248 |
NP_002466 |
MLC1SA |
myosin light chain 1 slow a |
Cytoplasm |
other |
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|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00481873 |
NP_004334 |
CALR |
calreticulin |
Nucleus |
transcription regulator |
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| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00490239 |
NP_006748 |
TNNT3 |
troponin T type 3 (skeletal, fast) |
Unknown |
other |
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| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00486393 |
NP_032939 |
PPP3CA |
protein phosphatase 3 (formerly 2B), catalytic subunit, alpha
isoform (calcineurin A alpha) |
Cytoplasm |
phosphatase |
cyclosporin A, pimecrolimus,
tacrolimus |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00483275 |
NP_033420 |
TNNC2 |
troponin C type 2 (fast) |
Unknown |
other |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00511139 |
NP_033431 |
TNNI2 |
troponin I type 2 (skeletal, fast) |
Unknown |
enzyme |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00506105 |
NP_033442 |
TPM2 |
tropomyosin 2 (beta) |
Cytoplasm |
other |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00492396 |
NP_033738 |
ACTC |
actin, alpha, cardiac muscle |
Cytoplasm |
other |
|
23_167 |
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00492774 |
NP_034990 |
MYL6 |
myosin, light polypeptide 6, alkali, smooth muscle and
non-muscle |
Cytoplasm |
other |
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|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00503219 |
NP_067442 |
TNNI1 |
troponin I type 1 (skeletal, slow) |
Unknown |
other |
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| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00513242 |
NP_074035 |
MYH11 |
myosin, heavy polypeptide 11, smooth muscle |
Cytoplasm |
other |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00484075 |
NP_109604 |
MYH1 |
myosin, heavy polypeptide 1, skeletal muscle, adult |
Cytoplasm |
enzyme |
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| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00607418 |
NP_115857 |
ASPH |
aspartate beta-hydroxylase |
Cytoplasm |
enzyme |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00499941 |
NP_524144 |
MYL1 |
myosin, light polypeptide 1, alkali; skeletal, fast |
Cytoplasm |
other |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00497758 |
NP_659210 |
MYH2 |
myosin, heavy polypeptide 2, skeletal muscle, adult |
Cytoplasm |
enzyme |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00508438 |
NP_733765 |
ATP2A2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
Cytoplasm |
transporter |
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|
|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00505794 |
NP_775293 |
ATP2A1 |
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
Cytoplasm |
transporter |
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|
| 2D LCMSMS |
canonical signaling |
calcium signalling |
IPI00484057 |
NP_796343 |
MYH8 |
myosin, heavy polypeptide 8, skeletal muscle, perinatal |
Cytoplasm |
other |
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|
|
| 2D LCMSMS |
canonical signaling |
call cycle G2/M DNA damage checkpoint |
IPI00487033 |
NP_006752 |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, epsilon polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
call cycle G2/M DNA damage checkpoint |
IPI00498898 |
NP_061223 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, beta polypeptide |
Cytoplasm |
other |
|
3_34 |
|
| 2D LCMSMS |
canonical signaling |
call cycle G2/M DNA damage checkpoint |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
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|
| 2D LCMSMS |
canonical signaling |
cAMP mediated signaling |
IPI00487399 |
NP_001010935 |
RAP1A |
RAP1A, member of RAS oncogene family |
Cytoplasm |
enzyme |
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|
|
| 2D LCMSMS |
canonical signaling |
cAMP mediated signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
cAMP mediated signaling |
IPI00486393 |
NP_032939 |
PPP3CA |
protein phosphatase 3 (formerly 2B), catalytic subunit, alpha
isoform (calcineurin A alpha) |
Cytoplasm |
phosphatase |
cyclosporin A, pimecrolimus,
tacrolimus |
4_145 |
|
| 2D LCMSMS |
canonical signaling |
cAMP mediated signaling |
IPI00486457 |
NP_066268 |
GNAO1 |
guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide O |
Plasma Membrane |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00493697 |
NP_002706 |
PPP2CA |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha
isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00485564 |
NP_058587 |
PPP2R1A |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), alpha isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00505088 |
NP_082890 |
PPP2R1B |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform |
Unknown |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00508438 |
NP_733765 |
ATP2A2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00505794 |
NP_775293 |
ATP2A1 |
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
Cytoplasm |
transporter |
|
7_77 |
|
| 2D LCMSMS |
canonical signaling |
Cardiac B adrenergic signalling |
IPI00493569 |
NP_996759 |
PPP1CB |
protein phosphatase 1, catalytic subunit, beta isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
chemokine signaling |
IPI00488085 |
NP_058034 |
HUMMLC2B |
fast skeletal myosin light chain 2 |
Cytoplasm |
other |
|
2_56 |
|
| 2D LCMSMS |
canonical signaling |
chemokine signaling |
IPI00507306 |
NP_058082 |
RHOA |
ras homolog gene family, member A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
complement and coagulation cascades |
IPI00515910 |
NP_001002235 |
SERPINA1 |
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase,
antitrypsin), member 1 |
Extracellular Space |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
complement and coagulation cascades |
IPI00486098 |
NP_033908 |
C3 |
complement component 3 |
Extracellular Space |
peptidase |
|
2_68 |
|
| 2D LCMSMS |
canonical signaling |
death receptor signaling |
IPI00483990 |
NP_031834 |
CYCS |
cytochrome c, somatic |
Cytoplasm |
enzyme |
|
1_51 |
|
| 2D LCMSMS |
canonical signaling |
Dopamine receptor signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
1_36 |
|
| 2D LCMSMS |
canonical signaling |
EGF signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
1_38 |
|
| 2D LCMSMS |
canonical signaling |
Endoplasmic reticulum stress pathway |
IPI00618170 |
NP_071705 |
HSPA5 |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Endoplasmic reticulum stress pathway |
IPI00491508 |
NP_080390 |
EIF2S1 |
eukaryotic translation initiation factor 2, subunit 1 alpha,
35kDa |
Cytoplasm |
translation regulator |
|
2_17 |
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00487399 |
NP_001010935 |
RAP1A |
RAP1A, member of RAS oncogene family |
Cytoplasm |
enzyme |
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|
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00493697 |
NP_002706 |
PPP2CA |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha
isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
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|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00492706 |
NP_002863 |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small
GTP binding protein Rac2) |
Cytoplasm |
enzyme |
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|
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00485564 |
NP_058587 |
PPP2R1A |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), alpha isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00498898 |
NP_061223 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, beta polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00482129 |
NP_061359 |
YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, gamma polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00505088 |
NP_082890 |
PPP2R1B |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform |
Unknown |
phosphatase |
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|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
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|
| 2D LCMSMS |
canonical signaling |
ERK/MAPK signaling |
IPI00493569 |
NP_996759 |
PPP1CB |
protein phosphatase 1, catalytic subunit, beta isoform |
Cytoplasm |
phosphatase |
|
10_121 |
|
| 2D LCMSMS |
canonical signaling |
estrogen receptor signaling |
IPI00512852 |
NP_001003810 |
HNRPD |
heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA
binding protein 1, 37kDa) |
Nucleus |
other |
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|
| 2D LCMSMS |
canonical signaling |
estrogen receptor signaling |
IPI00488168 |
NP_004387 |
DDX5 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5 |
Nucleus |
enzyme |
|
5_102 |
|
| 2D LCMSMS |
canonical signaling |
estrogen receptor signaling |
IPI00501947 |
NP_009204 |
PHB2 |
prohibitin 2 |
Plasma Membrane |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
estrogen receptor signaling |
IPI00497325 |
NP_035174 |
PCK1 |
phosphoenolpyruvate carboxykinase 1 (soluble) |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
estrogen receptor signaling |
IPI00507246 |
NP_081703 |
TAF15 |
TAF15 RNA polymerase II, TATA box binding protein
(TBP)-associated factor, 68kDa |
Nucleus |
transcription regulator |
|
|
|
| 2D LCMSMS |
canonical signaling |
GABA receptor signalling |
IPI00503163 |
NP_000654 |
ABAT |
4-aminobutyrate aminotransferase |
Cytoplasm |
enzyme |
valproic acid |
5_37 |
|
| 2D LCMSMS |
canonical signaling |
GABA receptor signalling |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
GABA receptor signalling |
IPI00512912 |
NP_001003908 |
CLTC |
clathrin, heavy polypeptide (Hc) |
Plasma Membrane |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
GABA receptor signalling |
IPI00496656 |
NP_004399 |
DNM1 |
dynamin 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
GABA receptor signalling |
IPI00506807 |
NP_032766 |
NSF |
N-ethylmaleimide-sensitive factor |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
canonical signaling |
glutamate receptor signalling |
IPI00499739 |
NP_001028216 |
GLUL |
glutamate-ammonia ligase (glutamine synthetase) |
Cytoplasm |
enzyme |
|
4_47 |
|
| 2D LCMSMS |
canonical signaling |
glutamate receptor signalling |
IPI00490358 |
NP_004162 |
SLC1A2 |
solute carrier family 1 (glial high affinity glutamate
transporter), member 2 |
Plasma Membrane |
transporter |
riluzole |
|
|
| 2D LCMSMS |
canonical signaling |
glutamate receptor signalling |
IPI00488985 |
NP_004163 |
SLC1A3 |
solute carrier family 1 (glial high affinity glutamate
transporter), member 3 |
Plasma Membrane |
transporter |
riluzole |
|
|
| 2D LCMSMS |
canonical signaling |
glutamate receptor signalling |
IPI00482094 |
NP_068775 |
GRIK2 |
glutamate receptor, ionotropic, kainate 2 |
Plasma Membrane |
ion channel |
|
|
|
| 2D LCMSMS |
canonical signaling |
GM-CSF signaling |
IPI00507097 |
NP_032169 |
GNB2L1 |
guanine nucleotide binding protein (G protein), beta
polypeptide 2-like 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
GM-CSF signaling |
IPI00486393 |
NP_032939 |
PPP3CA |
protein phosphatase 3 (formerly 2B), catalytic subunit, alpha
isoform (calcineurin A alpha) |
Cytoplasm |
phosphatase |
cyclosporin A, pimecrolimus,
tacrolimus |
2_50 |
|
| 2D LCMSMS |
canonical signaling |
G-protein coupled receptor signaling |
IPI00487399 |
NP_001010935 |
RAP1A |
RAP1A, member of RAS oncogene family |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
G-protein coupled receptor signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
G-protein coupled receptor signaling |
IPI00486457 |
NP_066268 |
GNAO1 |
guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide O |
Plasma Membrane |
enzyme |
|
3_157 |
|
| 2D LCMSMS |
canonical signaling |
Hypoxia signaling in the cardiovascular |
IPI00484713 |
NP_000909 |
P4HB |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline
4-hydroxylase), beta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Hypoxia signaling in the cardiovascular |
IPI00504902 |
NP_003339 |
UBE2N |
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Hypoxia signaling in the cardiovascular |
IPI00609956 |
NP_005339 |
HSPCA |
heat shock 90kDa protein 1, alpha |
Cytoplasm |
other |
|
5_44 |
|
| 2D LCMSMS |
canonical signaling |
Hypoxia signaling in the cardiovascular |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Hypoxia signaling in the cardiovascular |
IPI00512269 |
NP_034829 |
LDHA |
lactate dehydrogenase A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
IGF-1 signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
IGF-1 signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
5_67 |
|
| 2D LCMSMS |
canonical signaling |
IGF-1 signaling |
IPI00498898 |
NP_061223 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, beta polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
IGF-1 signaling |
IPI00500460 |
NP_061359 |
YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, gamma polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
IGF-1 signaling |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
IL-6 signaling |
IPI00486162 |
NP_000079 |
COL1A1 |
collagen, type I, alpha 1 |
Extracellular Space |
other |
|
2_68 |
|
| 2D LCMSMS |
canonical signaling |
IL-6 signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
insulin receptor signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
insulin receptor signaling |
IPI00609891 |
NP_033523 |
VAMP2 |
vesicle-associated membrane protein 2 (synaptobrevin 2) |
Plasma Membrane |
other |
botulism toxin |
|
|
| 2D LCMSMS |
canonical signaling |
insulin receptor signaling |
IPI00493569 |
NP_996759 |
PPP1CB |
protein phosphatase 1, catalytic subunit, beta isoform |
Cytoplasm |
phosphatase |
|
3_102 |
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00492961 |
NP_000079 |
COL1A1 |
collagen, type I, alpha 1 |
Extracellular Space |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00502653 |
NP_000080 |
COL1A2 |
collagen, type I, alpha 2 |
Extracellular Space |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00487399 |
NP_001010935 |
RAP1A |
RAP1A, member of RAS oncogene family |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00513339 |
NP_001019399 |
ARF1 |
ADP-ribosylation factor 1 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00507577 |
NP_001093 |
ACTN1 |
actinin, alpha 1 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00611653 |
NP_001095 |
ACTN3 |
actinin, alpha 3 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00492706 |
NP_002863 |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small
GTP binding protein Rac2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00508338 |
NP_004915 |
ACTN4 |
actinin, alpha 4 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00487834 |
NP_031642 |
CAV1 |
caveolin 1, caveolae protein, 22kDa |
Plasma Membrane |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00492396 |
NP_033738 |
ACTC |
actin, alpha, cardiac muscle |
Cytoplasm |
other |
|
14_164 |
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00482295 |
NP_033739 |
ACTG1 |
actin, gamma 1 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00507306 |
NP_058082 |
RHOA |
ras homolog gene family, member A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00610381 |
NP_150371 |
ACTN2 |
actinin, alpha 2 |
Nucleus |
transcription regulator |
|
|
|
| 2D LCMSMS |
canonical signaling |
Integrin signalling |
IPI00483517 |
NP_690601 |
ARPC2 |
actin related protein 2/3 complex, subunit 2, 34kDa |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Neurotrophin/Trk signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
1_48 |
|
| 2D LCMSMS |
canonical signaling |
NF-KB signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
NF-KB signaling |
IPI00504902 |
NP_003339 |
UBE2N |
ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
NF-KB signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
3_107 |
|
| 2D LCMSMS |
canonical signaling |
Nitric oxide signalling in the cardiovascular |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Nitric oxide signalling in the cardiovascular |
IPI00609956 |
NP_005339 |
HSPCA |
heat shock 90kDa protein 1, alpha |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Nitric oxide signalling in the cardiovascular |
IPI00487834 |
NP_031642 |
CAV1 |
caveolin 1, caveolae protein, 22kDa |
Plasma Membrane |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Nitric oxide signalling in the cardiovascular |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
Nitric oxide signalling in the cardiovascular |
IPI00508438 |
NP_733765 |
ATP2A2 |
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
canonical signaling |
Nitric oxide signalling in the cardiovascular |
IPI00505794 |
NP_775293 |
ATP2A1 |
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 |
Cytoplasm |
transporter |
|
6_41 |
|
| 2D LCMSMS |
canonical signaling |
p38 MAPK signaling |
IPI00512078 |
NP_057216 |
MYEF2 |
myelin expression factor 2 |
Nucleus |
transcription regulator |
|
1_61 |
|
| 2D LCMSMS |
canonical signaling |
Parkinsons Signalling |
IPI00494877 |
NP_002679 |
SEPT,5 |
septin 5 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
Parkinsons Signalling |
IPI00512853 |
NP_004172 |
UCHL1 |
ubiquitin carboxyl-terminal esterase L1 (ubiquitin
thiolesterase) |
Cytoplasm |
peptidase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Parkinsons Signalling |
IPI00483990 |
NP_031834 |
CYCS |
cytochrome c, somatic |
Cytoplasm |
enzyme |
|
4_17 |
|
| 2D LCMSMS |
canonical signaling |
Parkinsons Signalling |
IPI00612196 |
NP_695012 |
UBE1 |
ubiquitin-activating enzyme E1 (A1S9T and BN75 temperature
sensitivity complementing) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
PDGF signaling |
IPI00487834 |
NP_031642 |
CAV1 |
caveolin 1, caveolae protein, 22kDa |
Plasma Membrane |
other |
|
2_54 |
|
| 2D LCMSMS |
canonical signaling |
PDGF signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
canonical signaling |
Phototransduction |
IPI00484130 |
NP_000504 |
OPN1MW |
opsin 1 (cone pigments), medium-wave-sensitive (color
blindness, deutan) |
Plasma Membrane |
G-protein coupled receptor |
|
4_24 |
|
| 2D LCMSMS |
canonical signaling |
Phototransduction |
IPI00504217 |
NP_000530 |
RHO |
rhodopsin (opsin 2, rod pigment) (retinitis pigmentosa 4,
autosomal dominant) |
Plasma Membrane |
G-protein coupled receptor |
|
|
|
| 2D LCMSMS |
canonical signaling |
Phototransduction |
IPI00483983 |
NP_031564 |
OPN1SW |
opsin 1 (cone pigments), short-wave-sensitive (color
blindness, tritan) |
Plasma Membrane |
G-protein coupled receptor |
|
|
|
| 2D LCMSMS |
canonical signaling |
Phototransduction |
IPI00503164 |
NP_033064 |
RCV1 |
recoverin |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
PI3K/AKT signaling |
IPI00493697 |
NP_002706 |
PPP2CA |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha
isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
PI3K/AKT signaling |
IPI00609956 |
NP_005339 |
HSPCA |
heat shock 90kDa protein 1, alpha |
Cytoplasm |
other |
|
6_88 |
|
| 2D LCMSMS |
canonical signaling |
PI3K/AKT signaling |
IPI00487033 |
NP_006752 |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, epsilon polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
PI3K/AKT signaling |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
PI3K/AKT signaling |
IPI00485564 |
NP_058587 |
PPP2R1A |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), alpha isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
PI3K/AKT signaling |
IPI00505088 |
NP_082890 |
PPP2R1B |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform |
Unknown |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
PPAR signaling |
IPI00609956 |
NP_005339 |
HSPCA |
heat shock 90kDa protein 1, alpha |
Cytoplasm |
other |
|
2_65 |
|
| 2D LCMSMS |
canonical signaling |
PPAR signaling |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
PTEN signaling |
IPI00492706 |
NP_002863 |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small
GTP binding protein Rac2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
PTEN signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
2_68 |
|
| 2D LCMSMS |
canonical signaling |
SAPK/JNK signaling |
IPI00492706 |
NP_002863 |
RAC2 |
ras-related C3 botulinum toxin substrate 2 (rho family, small
GTP binding protein Rac2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
SAPK/JNK signaling |
IPI00493887 |
NP_112552 |
HNRPK |
heterogeneous nuclear ribonucleoprotein K |
Nucleus |
other |
|
2_71 |
|
| 2D LCMSMS |
canonical signaling |
sonic hedgehog signaling |
IPI00493207 |
NP_002722 |
PRKACB |
protein kinase, cAMP-dependent, catalytic, beta |
Cytoplasm |
kinase |
|
1_22 |
|
| 2D LCMSMS |
canonical signaling |
T cell receptor signaling |
IPI00486393 |
NP_032939 |
PPP3CA |
protein phosphatase 3 (formerly 2B), catalytic subunit, alpha
isoform (calcineurin A alpha) |
Cytoplasm |
phosphatase |
cyclosporin A, pimecrolimus,
tacrolimus |
1_72 |
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00507577 |
NP_001093 |
ACTN1 |
actinin, alpha 1 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00611653 |
NP_001095 |
ACTN3 |
actinin, alpha 3 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00508338 |
NP_004915 |
ACTN4 |
actinin, alpha 4 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00483518 |
NP_006752 |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, epsilon polypeptide |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00492396 |
NP_033738 |
ACTC |
actin, alpha, cardiac muscle |
Cytoplasm |
other |
|
8_16 |
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00482295 |
NP_033739 |
ACTG1 |
actin, gamma 1 |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00491508 |
NP_080390 |
EIF2S1 |
eukaryotic translation initiation factor 2, subunit 1 alpha,
35kDa |
Cytoplasm |
translation regulator |
|
|
|
| 2D LCMSMS |
canonical signaling |
VEGF signalling |
IPI00610381 |
NP_150371 |
ACTN2 |
actinin, alpha 2 |
Nucleus |
transcription regulator |
|
|
|
| 2D LCMSMS |
canonical signaling |
wnt/b catenin signaling |
IPI00616795 |
NP_002323 |
LRP1 |
low density lipoprotein-related protein 1
(alpha-2-macroglobulin receptor) |
Plasma Membrane |
transmembrane receptor |
|
|
|
| 2D LCMSMS |
canonical signaling |
wnt/b catenin signaling |
IPI00493697 |
NP_002706 |
PPP2CA |
protein phosphatase 2 (formerly 2A), catalytic subunit, alpha
isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
wnt/b catenin signaling |
IPI00497366 |
NP_034105 |
CSNK2B |
casein kinase 2, beta polypeptide |
Cytoplasm |
kinase |
|
6_129 |
|
| 2D LCMSMS |
canonical signaling |
wnt/b catenin signaling |
IPI00485564 |
NP_058587 |
PPP2R1A |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), alpha isoform |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
canonical signaling |
wnt/b catenin signaling |
IPI00486457 |
NP_066268 |
GNAO1 |
guanine nucleotide binding protein (G protein), alpha
activating activity polypeptide O |
Plasma Membrane |
enzyme |
|
|
|
| 2D LCMSMS |
canonical signaling |
wnt/b catenin signaling |
IPI00505088 |
NP_082890 |
PPP2R1B |
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR
65), beta isoform |
Unknown |
phosphatase |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00515939 |
NP_001018005 |
TPM1 |
tropomyosin 1 (alpha) |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
integrin signaling |
IPI00618953 |
NP_001092 |
ACTB |
actin, beta |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
VEGF signaling |
IPI00618953 |
NP_001092 |
ACTB |
actin, beta |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00501621 |
NP_002462 |
MYH6 |
myosin, heavy polypeptide 6, cardiac muscle, alpha
(cardiomyopathy, hypertrophic 1) |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00494375 |
NP_003281 |
TPM4 |
tropomyosin 4 |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
antigen presentation pathway |
IPI00612351 |
NP_004334 |
CALR |
calreticulin |
Nucleus |
transcription regulator |
|
1_42 |
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00612351 |
NP_004334 |
CALR |
calreticulin |
Nucleus |
transcription regulator |
|
|
|
| 2D PAGE |
canonical signaling |
cell cycle:G2/M DNA damage checkpoint |
IPI00483518 |
NP_006752 |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, epsilon polypeptide |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
PI3K/AKT signaling |
IPI00483518 |
NP_006752 |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, epsilon polypeptide |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
VEGF signaling |
IPI00483518 |
NP_006752 |
YWHAE |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, epsilon polypeptide |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00551994 |
NP_031418 |
ACTA2 |
actin, alpha 2, smooth muscle, aorta |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
integrin signaling |
IPI00551994 |
NP_031418 |
ACTA2 |
actin, alpha 2, smooth muscle, aorta |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
VEGF signaling |
IPI00551994 |
NP_031418 |
ACTA2 |
actin, alpha 2, smooth muscle, aorta |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
PI3K/AKT signaling |
IPI00613109 |
NP_031640 |
CTNNB1 |
catenin (cadherin-associated protein), beta 1, 88kDa |
Nucleus |
transcription regulator |
|
3_88 |
|
| 2D PAGE |
canonical signaling |
Wnt/B-catenin signaling |
IPI00613109 |
NP_031640 |
CTNNB1 |
catenin (cadherin-associated protein), beta 1, 88kDa |
Nucleus |
transcription regulator |
|
1_129 |
|
| 2D PAGE |
canonical signaling |
hypoxia signaling in the cardiovascular |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
1_44 |
|
| 2D PAGE |
canonical signaling |
nitric oxide signaling in the cardiovascular |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
1_41 |
|
| 2D PAGE |
canonical signaling |
PI3K/AKT signaling |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
PPAR signaling |
IPI00491598 |
NP_032328 |
HSPCB |
heat shock 90kDa protein 1, beta |
Cytoplasm |
other |
|
1_65 |
|
| 2D PAGE |
canonical signaling |
apoptosis signaling |
IPI00502549 |
NP_032885 |
PRKCQ |
protein kinase C, theta |
Cytoplasm |
kinase |
|
1_68 |
|
| 2D PAGE |
canonical signaling |
Bcell receptor signaling |
IPI00502549 |
NP_032885 |
PRKCQ |
protein kinase C, theta |
Cytoplasm |
kinase |
|
1_115 |
|
| 2D PAGE |
canonical signaling |
NF-kB signaling |
IPI00502549 |
NP_032885 |
PRKCQ |
protein kinase C, theta |
Cytoplasm |
kinase |
|
1_107 |
|
| 2D PAGE |
canonical signaling |
Tcell receptor signaling |
IPI00502549 |
NP_032885 |
PRKCQ |
protein kinase C, theta |
Cytoplasm |
kinase |
|
1_72 |
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00506105 |
NP_033442 |
TPM2 |
tropomyosin 2 (beta) |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00570197 |
NP_033736 |
ACTA1 |
actin, alpha 1, skeletal muscle |
Cytoplasm |
other |
|
14_167 |
|
| 2D PAGE |
canonical signaling |
integrin signaling |
IPI00570197 |
NP_033736 |
ACTA1 |
actin, alpha 1, skeletal muscle |
Cytoplasm |
other |
|
5_164 |
|
| 2D PAGE |
canonical signaling |
VEGF signaling |
IPI00570197 |
NP_033736 |
ACTA1 |
actin, alpha 1, skeletal muscle |
Cytoplasm |
other |
|
6_66 |
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00551966 |
NP_033738 |
ACTC |
actin, alpha, cardiac muscle |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
integrin signaling |
IPI00551966 |
NP_033738 |
ACTC |
actin, alpha, cardiac muscle |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
VEGF signaling |
IPI00551966 |
NP_033738 |
ACTC |
actin, alpha, cardiac muscle |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
integrin signaling |
IPI00482295 |
NP_033739 |
ACTG1 |
actin, gamma 1 |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
VEGF signaling |
IPI00482295 |
NP_033739 |
ACTG1 |
actin, gamma 1 |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00616801 |
NP_034985 |
MYH4 |
myosin, heavy polypeptide 4, skeletal muscle |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
canonical signaling |
chemokine signaling |
IPI00496651 |
NP_058034 |
HUMMLC2B |
fast skeletal myosin light chain 2 |
Cytoplasm |
other |
|
1_56 |
|
| 2D PAGE |
canonical signaling |
cell cycle:G2/M DNA damage checkpoint |
IPI00498898 |
NP_061223 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, beta polypeptide |
Cytoplasm |
other |
|
3_34 |
|
| 2D PAGE |
canonical signaling |
ERK/MAPK signaling |
IPI00498898 |
NP_061223 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, beta polypeptide |
Cytoplasm |
other |
|
3_121 |
|
| 2D PAGE |
canonical signaling |
IGF-1 signaling |
IPI00498898 |
NP_061223 |
YWHAB |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, beta polypeptide |
Cytoplasm |
other |
|
3_67 |
|
| 2D PAGE |
canonical signaling |
ERK/MAPK signaling |
IPI00500460 |
NP_061359 |
YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, gamma polypeptide |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
IGF-1 signaling |
IPI00500460 |
NP_061359 |
YWHAG |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, gamma polypeptide |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
endoplasmic reticulum stress pathway |
IPI00618170 |
NP_071705 |
HSPA5 |
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) |
Cytoplasm |
other |
|
1_17 |
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00503572 |
NP_109604 |
MYH1 |
myosin, heavy polypeptide 1, skeletal muscle, adult |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00499941 |
NP_524144 |
MYL1 |
myosin, light polypeptide 1, alkali; skeletal, fast |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00497758 |
NP_659210 |
MYH2 |
myosin, heavy polypeptide 2, skeletal muscle, adult |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
canonical signaling |
cell cycle:G2/M DNA damage checkpoint |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
canonical signaling |
ERK/MAPK signaling |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
canonical signaling |
IGF-1 signaling |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00509838 |
NP_796343 |
MYH8 |
myosin, heavy polypeptide 8, skeletal muscle, perinatal |
Cytoplasm |
other |
|
|
|
| 2D PAGE |
canonical signaling |
calcium signaling |
IPI00509746 |
XP_913340 |
MYH13 |
myosin, heavy polypeptide 13, skeletal muscle |
Cytoplasm |
other |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00503163 |
NP_000654 |
ABAT |
4-aminobutyrate aminotransferase |
Cytoplasm |
enzyme |
valproic acid |
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00609142 |
NP_001340 |
DARS |
aspartyl-tRNA synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00497028 |
NP_031520 |
ASS |
argininosuccinate synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00486567 |
NP_071504 |
PC |
pyruvate carboxylase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00512580 |
NP_597700 |
GPT2 |
glutamic pyruvate transaminase (alanine aminotransferase) 2 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00612969 |
NP_666329 |
AARS |
alanyl-tRNA synthetase |
Cytoplasm |
enzyme |
|
9_31 |
|
| 2D LCMSMS |
metabolic signaling |
alanine and aspartate metabolism |
IPI00490817 |
NP_689541 |
ADSSL1 |
adenylosuccinate synthase like 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
aminoacyl-tRNA biosynthesis |
IPI00609142 |
NP_001340 |
DARS |
aspartyl-tRNA synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
aminoacyl-tRNA biosynthesis |
IPI00504095 |
NP_006504 |
SARS |
seryl-tRNA synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
aminoacyl-tRNA biosynthesis |
IPI00612969 |
NP_666329 |
AARS |
alanyl-tRNA synthetase |
Cytoplasm |
enzyme |
|
3_33 |
|
| 2D LCMSMS |
metabolic signaling |
aminosugars metabolism |
IPI00613630 |
NP_075675 |
CHIA |
chitinase, acidic |
Extracellular Space |
enzyme |
|
1_30 |
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00503812 |
NP_000147 |
GAMT |
guanidinoacetate N-methyltransferase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00484713 |
NP_000909 |
P4HB |
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline
4-hydroxylase), beta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00497388 |
NP_001814 |
CKB |
creatine kinase, brain |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00609872 |
NP_001815 |
CKM |
creatine kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00503075 |
NP_001816 |
CKMT2 |
creatine kinase, mitochondrial 2 (sarcomeric) |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00483853 |
NP_005262 |
GLUD1 |
glutamate dehydrogenase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00497028 |
NP_031520 |
ASS |
argininosuccinate synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
12_65 |
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
arginine and proline metabolism |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ascorbate and aldarate metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ascorbate and aldarate metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ascorbate and aldarate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
3_12 |
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00554392 |
NP_000007 |
ACADM |
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00510456 |
NP_000009 |
ACADVL |
acyl-Coenzyme A dehydrogenase, very long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00503163 |
NP_000654 |
ABAT |
4-aminobutyrate aminotransferase |
Cytoplasm |
enzyme |
valproic acid |
12_50 |
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00483740 |
NP_031407 |
ACADL |
acyl-Coenzyme A dehydrogenase, long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00509410 |
NP_033494 |
DPYSL3 |
dihydropyrimidinase-like 3 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00493073 |
NP_034085 |
DPYSL2 |
dihydropyrimidinase-like 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
b-alanine metabolism |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00490409 |
NP_000662 |
ADH5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00484255 |
NP_666342 |
MGC29978 |
3-ketoacyl-CoA thiolase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
bile acid biosynthesis |
IPI00500184 |
NP_803421 |
ACAA2 |
acetyl-Coenzyme A acyltransferase 2 (mitochondrial
3-oxoacyl-Coenzyme A thiolase) |
Cytoplasm |
enzyme |
|
7_37 |
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00616094 |
NP_000275 |
PDHA1 |
pyruvate dehydrogenase (lipoamide) alpha 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00485562 |
NP_000427 |
OXCT1 |
3-oxoacid CoA transferase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00503163 |
NP_000654 |
ABAT |
4-aminobutyrate aminotransferase |
Cytoplasm |
enzyme |
valproic acid |
12_47 |
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00512330 |
NP_005318 |
HADHSC |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00489732 |
NP_035637 |
SUCLG2 |
succinate-CoA ligase, GDP-forming, beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
butanoate metabolism |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00500416 |
NP_002159 |
IDH2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00551885 |
NP_002532 |
OGDH |
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00495512 |
NP_005908 |
MDH1 |
malate dehydrogenase 1, NAD (soluble) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00491947 |
NP_031412 |
ACO1 |
aconitase 1, soluble |
Cytoplasm |
enzyme |
|
13_27 |
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00512157 |
NP_032643 |
MDH2 |
malate dehydrogenase 2, NAD (mitochondrial) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00497325 |
NP_035174 |
PCK1 |
phosphoenolpyruvate carboxykinase 1 (soluble) |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00497153 |
NP_035636 |
SUCLA2 |
succinate-CoA ligase, ADP-forming, beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00489732 |
NP_035637 |
SUCLG2 |
succinate-CoA ligase, GDP-forming, beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00486567 |
NP_071504 |
PC |
pyruvate carboxylase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00498165 |
NP_080720 |
CS |
citrate synthase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00496649 |
NP_083849 |
IDH3A |
isocitrate dehydrogenase 3 (NAD+) alpha |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Citrate cycle |
IPI00483652 |
NP_542364 |
ACO2 |
aconitase 2, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
cysteine metabolism |
IPI00508477 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
cysteine metabolism |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
4_14 |
|
| 2D LCMSMS |
metabolic signaling |
cysteine metabolism |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
cysteine metabolism |
IPI00512269 |
NP_034829 |
LDHA |
lactate dehydrogenase A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00512330 |
NP_005318 |
HADHSC |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00484255 |
NP_666342 |
MGC29978 |
3-ketoacyl-CoA thiolase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00500184 |
NP_803421 |
ACAA2 |
acetyl-Coenzyme A acyltransferase 2 (mitochondrial
3-oxoacyl-Coenzyme A thiolase) |
Cytoplasm |
enzyme |
|
7_18 |
|
| 2D LCMSMS |
metabolic signaling |
fatty acid biosynthesis (pathway 2) |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00554392 |
NP_000007 |
ACADM |
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00510456 |
NP_000009 |
ACADVL |
acyl-Coenzyme A dehydrogenase, very long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00490409 |
NP_000662 |
ADH5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00512330 |
NP_005318 |
HADHSC |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00483740 |
NP_031407 |
ACADL |
acyl-Coenzyme A dehydrogenase, long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00498960 |
NP_034153 |
DCI |
dodecenoyl-Coenzyme A delta isomerase (3,2
trans-enoyl-Coenzyme A isomerase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00484255 |
NP_666342 |
MGC29978 |
3-ketoacyl-CoA thiolase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00500184 |
NP_803421 |
ACAA2 |
acetyl-Coenzyme A acyltransferase 2 (mitochondrial
3-oxoacyl-Coenzyme A thiolase) |
Cytoplasm |
enzyme |
|
15_133 |
|
| 2D LCMSMS |
metabolic signaling |
fatty acid metaboism |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00494768 |
NP_000280 |
PFKM |
phosphofructokinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00484161 |
NP_000356 |
TPI1 |
triosephosphate isomerase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00499849 |
NP_031464 |
ALDOA |
aldolase A, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00618628 |
NP_032852 |
PFKL |
phosphofructokinase, liver |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00511575 |
NP_060760 |
PGM2 |
phosphoglucomutase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00505184 |
NP_659152 |
ALDOB |
aldolase B, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
fructose and manose metabolism |
IPI00513405 |
NP_697021 |
AKR1A1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
Unknown |
enzyme |
|
8_47 |
|
| 2D LCMSMS |
metabolic signaling |
galactose metabolism |
IPI00494768 |
NP_000280 |
PFKM |
phosphofructokinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
galactose metabolism |
IPI00487547 |
NP_002624 |
PGM1 |
phosphoglucomutase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
galactose metabolism |
IPI00618628 |
NP_032852 |
PFKL |
phosphofructokinase, liver |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
galactose metabolism |
IPI00511575 |
NP_060760 |
PGM2 |
phosphoglucomutase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
galactose metabolism |
IPI00513405 |
NP_697021 |
AKR1A1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
Unknown |
enzyme |
|
5_49 |
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00503163 |
NP_000654 |
ABAT |
4-aminobutyrate aminotransferase |
Cytoplasm |
enzyme |
valproic acid |
7_37 |
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00499739 |
NP_001028216 |
GLUL |
glutamate-ammonia ligase (glutamine synthetase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00483853 |
NP_005262 |
GLUD1 |
glutamate dehydrogenase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00489732 |
NP_035637 |
SUCLG2 |
succinate-CoA ligase, GDP-forming, beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutamate metabolism |
IPI00512580 |
NP_597700 |
GPT2 |
glutamic pyruvate transaminase (alanine aminotransferase) 2 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutathione metabolism |
IPI00502668 |
NP_000843 |
GSTP1 |
glutathione S-transferase pi |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutathione metabolism |
IPI00500416 |
NP_002159 |
IDH2 |
isocitrate dehydrogenase 2 (NADP+), mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glutathione metabolism |
IPI00509532 |
NP_034487 |
GSTA4 |
glutathione S-transferase A4 |
Cytoplasm |
enzyme |
|
4_63 |
|
| 2D LCMSMS |
metabolic signaling |
glutathione metabolism |
IPI00496649 |
NP_083849 |
IDH3A |
isocitrate dehydrogenase 3 (NAD+) alpha |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycerolipid metabolism |
IPI00490409 |
NP_000662 |
ADH5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
Cytoplasm |
enzyme |
|
5_83 |
|
| 2D LCMSMS |
metabolic signaling |
glycerolipid metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycerolipid metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycerolipid metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
glycerolipid metabolism |
IPI00513405 |
NP_697021 |
AKR1A1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycerophospholipid metabolism |
IPI00484865 |
NP_034401 |
GPD1 |
glycerol-3-phosphate dehydrogenase 1 (soluble) |
Cytoplasm |
enzyme |
|
1_80 |
|
| 2D LCMSMS |
metabolic signaling |
glycine serine and threonine metabolism |
IPI00503812 |
NP_000147 |
GAMT |
guanidinoacetate N-methyltransferase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycine serine and threonine metabolism |
IPI00491662 |
NP_001704 |
BHMT |
betaine-homocysteine methyltransferase |
Cytoplasm |
enzyme |
|
5_48 |
|
| 2D LCMSMS |
metabolic signaling |
glycine serine and threonine metabolism |
IPI00504095 |
NP_006504 |
SARS |
seryl-tRNA synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycine serine and threonine metabolism |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycine serine and threonine metabolism |
IPI00481475 |
NP_619606 |
SARDH |
sarcosine dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00487456 |
NP_000166 |
GPI |
glucose phosphate isomerase |
Extracellular Space |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00616094 |
NP_000275 |
PDHA1 |
pyruvate dehydrogenase (lipoamide) alpha 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00494768 |
NP_000280 |
PFKM |
phosphofructokinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00501310 |
NP_000281 |
PGAM2 |
phosphoglycerate mutase 2 (muscle) |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00508365 |
NP_000282 |
PGK1 |
phosphoglycerate kinase 1 |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00484161 |
NP_000356 |
TPI1 |
triosephosphate isomerase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00490409 |
NP_000662 |
ADH5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
Cytoplasm |
enzyme |
|
26_91 |
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00483215 |
NP_001419 |
ENO1 |
enolase 1, (alpha) |
Cytoplasm |
transcription regulator |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00497753 |
NP_002037 |
GAPD |
glyceraldehyde-3-phosphate dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00495855 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00509016 |
NP_002620 |
PGAM1 |
phosphoglycerate mutase 1 (brain) |
Cytoplasm |
phosphatase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00487547 |
NP_002624 |
PGM1 |
phosphoglucomutase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00609989 |
NP_002645 |
PKM2 |
pyruvate kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00499849 |
NP_031464 |
ALDOA |
aldolase A, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00490877 |
NP_031959 |
ENO3 |
enolase 3 (beta, muscle) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00618628 |
NP_032852 |
PFKL |
phosphofructokinase, liver |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00512269 |
NP_034829 |
LDHA |
lactate dehydrogenase A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00487455 |
NP_055179 |
GAPDS |
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00511575 |
NP_060760 |
PGM2 |
phosphoglucomutase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00505184 |
NP_659152 |
ALDOB |
aldolase B, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00513405 |
NP_697021 |
AKR1A1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glyoxylate and dicarboxylate metabolism |
IPI00495512 |
NP_005908 |
MDH1 |
malate dehydrogenase 1, NAD (soluble) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glyoxylate and dicarboxylate metabolism |
IPI00491947 |
NP_031412 |
ACO1 |
aconitase 1, soluble |
Cytoplasm |
enzyme |
|
5_16 |
|
| 2D LCMSMS |
metabolic signaling |
glyoxylate and dicarboxylate metabolism |
IPI00512157 |
NP_032643 |
MDH2 |
malate dehydrogenase 2, NAD (mitochondrial) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glyoxylate and dicarboxylate metabolism |
IPI00498165 |
NP_080720 |
CS |
citrate synthase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
glyoxylate and dicarboxylate metabolism |
IPI00483652 |
NP_542364 |
ACO2 |
aconitase 2, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
histidine metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
histidine metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
histidine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
3_35 |
|
| 2D LCMSMS |
metabolic signaling |
Inositol Metabolism |
IPI00484161 |
NP_000356 |
TPI1 |
triosephosphate isomerase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Inositol Metabolism |
IPI00499849 |
NP_031464 |
ALDOA |
aldolase A, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Inositol Metabolism |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
Inositol Metabolism |
IPI00512371 |
NP_598803 |
ALDH6A1 |
aldehyde dehydrogenase 6 family, member A1 |
Cytoplasm |
enzyme |
|
5_6 |
|
| 2D LCMSMS |
metabolic signaling |
Inositol Metabolism |
IPI00505184 |
NP_659152 |
ALDOB |
aldolase B, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
9_51 |
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00551885 |
NP_002532 |
OGDH |
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00512330 |
NP_005318 |
HADHSC |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
lysine degradation |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
methane metabolism |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
1_13 |
|
| 2D LCMSMS |
metabolic signaling |
methionine metabolism |
IPI00506192 |
NP_000678 |
AHCY |
S-adenosylhomocysteine hydrolase |
Cytoplasm |
enzyme |
|
3_19 |
|
| 2D LCMSMS |
metabolic signaling |
methionine metabolism |
IPI00491662 |
NP_001704 |
BHMT |
betaine-homocysteine methyltransferase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
methionine metabolism |
IPI00612599 |
NP_005902 |
MAT2A |
methionine adenosyltransferase II, alpha |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
n-glycan biosynthesis |
IPI00509272 |
NP_002942 |
RPN2 |
ribophorin II |
Cytoplasm |
enzyme |
|
1_36 |
|
| 2D LCMSMS |
metabolic signaling |
nicotinate and nicotinamide metabolism |
IPI00508462 |
NP_036475 |
NNT |
nicotinamide nucleotide transhydrogenase |
Cytoplasm |
enzyme |
|
1_29 |
|
| 2D LCMSMS |
metabolic signaling |
nitrogen metabolism |
IPI00499739 |
NP_001028216 |
GLUL |
glutamate-ammonia ligase (glutamine synthetase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
nitrogen metabolism |
IPI00483853 |
NP_005262 |
GLUD1 |
glutamate dehydrogenase 1 |
Cytoplasm |
enzyme |
|
3_34 |
|
| 2D LCMSMS |
metabolic signaling |
nitrogen metabolism |
IPI00481475 |
NP_619606 |
SARDH |
sarcosine dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
one carbon pool by folate |
IPI00501402 |
NP_004035 |
ATIC |
5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase/IMP cyclohydrolase |
Unknown |
enzyme |
|
2_19 |
|
| 2D LCMSMS |
metabolic signaling |
one carbon pool by folate |
IPI00481475 |
NP_619606 |
SARDH |
sarcosine dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00490401 |
NP_001001973 |
ATP5C1 |
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma
polypeptide 1 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00496195 |
NP_001679 |
ATP5F1 |
ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit B1 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00570320 |
NP_001684 |
ATP6V1B2 |
ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00495780 |
NP_001687 |
ATP6V1E1 |
ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00483070 |
NP_001688 |
ATP5O |
ATP synthase, H+ transporting, mitochondrial F1 complex, O
subunit (oligomycin sensitivity conferring
protein) |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00505260 |
NP_001852 |
COX4I1 |
cytochrome c oxidase subunit IV isoform 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00484560 |
NP_002484 |
NDUFB6 |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00496979 |
NP_003356 |
UQCRC1 |
ubiquinol-cytochrome c reductase core protein I |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00501589 |
NP_003357 |
UQCRC2 |
ubiquinol-cytochrome c reductase core protein II |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00499213 |
NP_004535 |
NDUFA10 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00501774 |
NP_004709 |
COX7A2L |
cytochrome c oxidase subunit VIIa polypeptide 2 like |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00618809 |
NP_004993 |
NDUFA9 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00484712 |
NP_006347 |
ATP5H |
ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit d |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00505301 |
NP_006467 |
ATP5L |
ATP synthase, H+ transporting, mitochondrial F0 complex,
subunit g |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00501377 |
NP_009034 |
NDUFV1 |
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00491975 |
NP_031531 |
ATP5A1 |
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha
subunit 1, cardiac muscle |
Cytoplasm |
transporter |
|
30_143 |
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00483506 |
NP_031534 |
ATP6V1A |
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00488350 |
NP_031773 |
COX5A |
cytochrome c oxidase subunit Va |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00513099 |
NP_034072 |
COX5B |
cytochrome c oxidase subunit Vb |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00483018 |
NP_035016 |
NDUFA4 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00498104 |
NP_038505 |
ATP6V0D1 |
ATPase, H+ transporting, lysosomal 38kDa, V0 subunit D1 |
Cytoplasm |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00505335 |
NP_066952 |
PPA1 |
pyrophosphatase (inorganic) 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00513660 |
NP_075691 |
NDUFA7 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00494833 |
NP_075801 |
NDUFA13 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00497575 |
NP_079827 |
NDUFA12 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00612801 |
NP_079843 |
CYC1 |
cytochrome c-1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00491457 |
NP_079986 |
UQCRFS1 |
ubiquinol-cytochrome c reductase, Rieske iron-sulfur
polypeptide 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00512704 |
NP_080979 |
NDUFA8 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00501910 |
NP_694704 |
NDUFS2 |
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa
(NADH-coenzyme Q reductase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
oxidative phosphorylatipn |
IPI00506453 |
NP_904330 |
COX1 |
cytochrome c oxidase subunit I |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pantothenate and CoA biosynthesis |
IPI00509410 |
NP_033494 |
DPYSL3 |
dihydropyrimidinase-like 3 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pantothenate and CoA biosynthesis |
IPI00493073 |
NP_034085 |
DPYSL2 |
dihydropyrimidinase-like 2 |
Cytoplasm |
enzyme |
|
2_21 |
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00487456 |
NP_000166 |
GPI |
glucose phosphate isomerase |
Extracellular Space |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00494768 |
NP_000280 |
PFKM |
phosphofructokinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00487547 |
NP_002624 |
PGM1 |
phosphoglucomutase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00499849 |
NP_031464 |
ALDOA |
aldolase A, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
10_33 |
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00618628 |
NP_032852 |
PFKL |
phosphofructokinase, liver |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00498510 |
NP_033414 |
TKT |
transketolase (Wernicke-Korsakoff syndrome) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00511575 |
NP_060760 |
PGM2 |
phosphoglucomutase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00505184 |
NP_659152 |
ALDOB |
aldolase B, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pentose phosphate pathway |
IPI00613160 |
NP_689953 |
HIBADH |
3-hydroxyisobutyrate dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine metabolism |
IPI00513570 |
NP_002406 |
MIF |
macrophage migration inhibitory factor
(glycosylation-inhibiting factor) |
Extracellular Space |
cytokine |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
5_28 |
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine metabolism |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine metabolism |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine metabolism |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine tyrosine and tryptophan |
IPI00483215 |
NP_001419 |
ENO1 |
enolase 1, (alpha) |
Cytoplasm |
transcription regulator |
|
4_14 |
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine tyrosine and tryptophan |
IPI00490877 |
NP_031959 |
ENO3 |
enolase 3 (beta, muscle) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine tyrosine and tryptophan |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phenylalanine tyrosine and tryptophan |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
phospholipid degradation |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
1_50 |
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00554392 |
NP_000007 |
ACADM |
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00510456 |
NP_000009 |
ACADVL |
acyl-Coenzyme A dehydrogenase, very long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00503163 |
NP_000654 |
ABAT |
4-aminobutyrate aminotransferase |
Cytoplasm |
enzyme |
valproic acid |
16_59 |
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00495855 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00483740 |
NP_031407 |
ACADL |
acyl-Coenzyme A dehydrogenase, long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00512269 |
NP_034829 |
LDHA |
lactate dehydrogenase A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00497153 |
NP_035636 |
SUCLA2 |
succinate-CoA ligase, ADP-forming, beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00489732 |
NP_035637 |
SUCLG2 |
succinate-CoA ligase, GDP-forming, beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00512371 |
NP_598803 |
ALDH6A1 |
aldehyde dehydrogenase 6 family, member A1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
propanoate metabolism |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
prostaglandin and leukotriene metabolism |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
2_76 |
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00483373 |
NP_000027 |
AMPD1 |
adenosine monophosphate deaminase 1 (isoform M) |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00504861 |
NP_000874 |
IMPDH1 |
IMP (inosine monophosphate) dehydrogenase 1 |
Cytoplasm |
enzyme |
mycophenolic acid, rebetron,
ribavirin, thioguanine |
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00505523 |
NP_001029138 |
AK2 |
adenylate kinase 2 |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00502624 |
NP_001668 |
ATP1B1 |
ATPase, Na+/K+ transporting, beta 1 polypeptide |
Plasma Membrane |
transporter |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00609989 |
NP_002645 |
PKM2 |
pyruvate kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00498499 |
NP_002795 |
PSMC3 |
proteasome (prosome, macropain) 26S subunit, ATPase, 3 |
Nucleus |
transcription regulator |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00501402 |
NP_004035 |
ATIC |
5-aminoimidazole-4-carboxamide ribonucleotide
formyltransferase/IMP cyclohydrolase |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00490588 |
NP_004661 |
PAPSS2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00509630 |
NP_006494 |
PSMC4 |
proteasome (prosome, macropain) 26S subunit, ATPase, 4 |
Nucleus |
peptidase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00613421 |
NP_009057 |
VCP |
valosin-containing protein |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00502388 |
NP_031424 |
ADA |
adenosine deaminase |
Cytoplasm |
enzyme |
pentostatin |
20_262 |
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00497989 |
NP_032730 |
NME1 |
non-metastatic cells 1, protein (NM23A) expressed in |
Nucleus |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00495318 |
NP_032973 |
PSMC1 |
proteasome (prosome, macropain) 26S subunit, ATPase, 1 |
Nucleus |
peptidase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00495740 |
NP_033500 |
UOX |
urate oxidase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00502330 |
NP_062667 |
BAT1 |
HLA-B associated transcript 1 |
Nucleus |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00501538 |
NP_067490 |
AK1 |
adenylate kinase 1 |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00507865 |
NP_080235 |
PSMC6 |
proteasome (prosome, macropain) 26S subunit, ATPase, 6 |
Nucleus |
peptidase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00484075 |
NP_109604 |
MYH1 |
myosin, heavy polypeptide 1, skeletal muscle, adult |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00490817 |
NP_689541 |
ADSSL1 |
adenylosuccinate synthase like 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
purine metabolism |
IPI00510085 |
NP_932099 |
DDX39 |
DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 |
Nucleus |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyrimidine metabolism |
IPI00493073 |
NP_034085 |
DPYSL2 |
dihydropyrimidinase-like 2 |
Cytoplasm |
enzyme |
|
4_146 |
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
16_72 |
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00616094 |
NP_000275 |
PDHA1 |
pyruvate dehydrogenase (lipoamide) alpha 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00508477 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00609989 |
NP_002645 |
PKM2 |
pyruvate kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00495512 |
NP_005908 |
MDH1 |
malate dehydrogenase 1, NAD (soluble) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00512157 |
NP_032643 |
MDH2 |
malate dehydrogenase 2, NAD (mitochondrial) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00512269 |
NP_034829 |
LDHA |
lactate dehydrogenase A |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00497325 |
NP_035174 |
PCK1 |
phosphoenolpyruvate carboxykinase 1 (soluble) |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00486567 |
NP_071504 |
PC |
pyruvate carboxylase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00513405 |
NP_697021 |
AKR1A1 |
aldo-keto reductase family 1, member A1 (aldehyde reductase) |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
pyruvate metabolism |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
selenoamino acid metabolism |
IPI00506192 |
NP_000678 |
AHCY |
S-adenosylhomocysteine hydrolase |
Cytoplasm |
enzyme |
|
3_21 |
|
| 2D LCMSMS |
metabolic signaling |
selenoamino acid metabolism |
IPI00490588 |
NP_004661 |
PAPSS2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
selenoamino acid metabolism |
IPI00612599 |
NP_005902 |
MAT2A |
methionine adenosyltransferase II, alpha |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
starch and sucrose metaboliam |
IPI00487456 |
NP_000166 |
GPI |
glucose phosphate isomerase |
Extracellular Space |
enzyme |
|
5_84 |
|
| 2D LCMSMS |
metabolic signaling |
starch and sucrose metaboliam |
IPI00509069 |
NP_002442 |
MTAP |
methylthioadenosine phosphorylase |
Nucleus |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
starch and sucrose metaboliam |
IPI00487547 |
NP_002624 |
PGM1 |
phosphoglucomutase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
starch and sucrose metaboliam |
IPI00484650 |
NP_002854 |
PYGL |
phosphorylase, glycogen; liver (Hers disease, glycogen storage
disease type VI) |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
starch and sucrose metaboliam |
IPI00511575 |
NP_060760 |
PGM2 |
phosphoglucomutase 2 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
stilbene coumarine and lignin biosynthesis |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
1_14 |
|
| 2D LCMSMS |
metabolic signaling |
sulfur metabolism |
IPI00490588 |
NP_004661 |
PAPSS2 |
3'-phosphoadenosine 5'-phosphosulfate synthase 2 |
Cytoplasm |
enzyme |
|
2_16 |
|
| 2D LCMSMS |
metabolic signaling |
sulfur metabolism |
IPI00508335 |
NP_058051 |
SULT1D1 |
sulfotransferase family 1D, member 1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
synthesis and degradation of ketone bodies |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
3_10 |
|
| 2D LCMSMS |
metabolic signaling |
synthesis and degradation of ketone bodies |
IPI00485562 |
NP_000427 |
OXCT1 |
3-oxoacid CoA transferase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
synthesis and degradation of ketone bodies |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
9_118 |
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00551885 |
NP_002532 |
OGDH |
oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00512330 |
NP_005318 |
HADHSC |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tryptophan metabolism |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tyrosine metabolism |
IPI00490409 |
NP_000662 |
ADH5 |
alcohol dehydrogenase 5 (class III), chi polypeptide |
Cytoplasm |
enzyme |
|
5_47 |
|
| 2D LCMSMS |
metabolic signaling |
tyrosine metabolism |
IPI00513570 |
NP_002406 |
MIF |
macrophage migration inhibitory factor
(glycosylation-inhibiting factor) |
Extracellular Space |
cytokine |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tyrosine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
tyrosine metabolism |
IPI00506920 |
NP_034454 |
GOT1 |
glutamic-oxaloacetic transaminase 1, soluble (aspartate
aminotransferase 1) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
tyrosine metabolism |
IPI00501009 |
NP_034455 |
GOT2 |
glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate
aminotransferase 2) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00484560 |
NP_002484 |
NDUFB6 |
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6, 17kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00499213 |
NP_004535 |
NDUFA10 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00618809 |
NP_004993 |
NDUFA9 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00501377 |
NP_009034 |
NDUFV1 |
NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00483018 |
NP_035016 |
NDUFA4 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa |
Cytoplasm |
enzyme |
|
10_49 |
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00513660 |
NP_075691 |
NDUFA7 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00494833 |
NP_075801 |
NDUFA13 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00497575 |
NP_079827 |
NDUFA12 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00512704 |
NP_080979 |
NDUFA8 |
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 8, 19kDa |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
ubiquinone biosynthesis |
IPI00501910 |
NP_694704 |
NDUFS2 |
NADH dehydrogenase (ubiquinone) Fe-S protein 2, 49kDa
(NADH-coenzyme Q reductase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00503812 |
NP_000147 |
GAMT |
guanidinoacetate N-methyltransferase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00609142 |
NP_001340 |
DARS |
aspartyl-tRNA synthetase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00497388 |
NP_001814 |
CKB |
creatine kinase, brain |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00609872 |
NP_001815 |
CKM |
creatine kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00503075 |
NP_001816 |
CKMT2 |
creatine kinase, mitochondrial 2 (sarcomeric) |
Cytoplasm |
kinase |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00483853 |
NP_005262 |
GLUD1 |
glutamate dehydrogenase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00497028 |
NP_031520 |
ASS |
argininosuccinate synthetase |
Cytoplasm |
enzyme |
|
8_29 |
|
| 2D LCMSMS |
metabolic signaling |
urea cycle and metabolism of amino acids |
IPI00481475 |
NP_619606 |
SARDH |
sarcosine dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine biosynthesis |
IPI00616094 |
NP_000275 |
PDHA1 |
pyruvate dehydrogenase (lipoamide) alpha 1 |
Cytoplasm |
enzyme |
|
1_12 |
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00554392 |
NP_000007 |
ACADM |
acyl-Coenzyme A dehydrogenase, C-4 to C-12 straight chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00510456 |
NP_000009 |
ACADVL |
acyl-Coenzyme A dehydrogenase, very long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00481049 |
NP_000010 |
ACAT1 |
acetyl-Coenzyme A acetyltransferase 1 (acetoacetyl Coenzyme A
thiolase) |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00485562 |
NP_000427 |
OXCT1 |
3-oxoacid CoA transferase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00507539 |
NP_000687 |
ALDH9A1 |
aldehyde dehydrogenase 9 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00483375 |
NP_001173 |
ALDH7A1 |
aldehyde dehydrogenase 7 family, member A1 |
Unknown |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00512330 |
NP_005318 |
HADHSC |
L-3-hydroxyacyl-Coenzyme A dehydrogenase, short chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00483740 |
NP_031407 |
ACADL |
acyl-Coenzyme A dehydrogenase, long chain |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00502389 |
NP_444349 |
ECHS1 |
enoyl Coenzyme A hydratase, short chain, 1, mitochondrial |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00512371 |
NP_598803 |
ALDH6A1 |
aldehyde dehydrogenase 6 family, member A1 |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00494197 |
NP_663533 |
HADHB |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), beta subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00484255 |
NP_666342 |
MGC29978 |
3-ketoacyl-CoA thiolase B |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00613160 |
NP_689953 |
HIBADH |
3-hydroxyisobutyrate dehydrogenase |
Cytoplasm |
enzyme |
|
|
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00500184 |
NP_803421 |
ACAA2 |
acetyl-Coenzyme A acyltransferase 2 (mitochondrial
3-oxoacyl-Coenzyme A thiolase) |
Cytoplasm |
enzyme |
|
16_61 |
|
| 2D LCMSMS |
metabolic signaling |
valine leucine and isoleucine degradation |
IPI00500793 |
NP_849209 |
HADHA |
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A
thiolase/enoyl-Coenzyme A hydratase (trifunctional
protein), alpha subunit |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
citrate cycle |
IPI00488038 |
NP_000134 |
FH |
fumarate hydratase |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
fructose and mannose metabolism |
IPI00619157 |
NP_000356 |
TPI1 |
triosephosphate isomerase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00619157 |
NP_000356 |
TPI1 |
triosephosphate isomerase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
Inositol metabolism |
IPI00619157 |
NP_000356 |
TPI1 |
triosephosphate isomerase 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
starch and sucrose metabolism |
IPI00511168 |
NP_000690 |
AMY2A |
amylase, alpha 2A; pancreatic |
Extracellular Space |
enzyme |
acarbose |
1_84 |
|
| 2D PAGE |
metabolic signaling |
butanoate metabolism |
IPI00506951 |
NP_000916 |
PDHB |
pyruvate dehydrogenase (lipoamide) beta |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00506951 |
NP_000916 |
PDHB |
pyruvate dehydrogenase (lipoamide) beta |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
pentose phosphate pathway |
IPI00506951 |
NP_000916 |
PDHB |
pyruvate dehydrogenase (lipoamide) beta |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
pyruvate metabolism |
IPI00506951 |
NP_000916 |
PDHB |
pyruvate dehydrogenase (lipoamide) beta |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
valine, leucine and isoleucine biosynthesis |
IPI00506951 |
NP_000916 |
PDHB |
pyruvate dehydrogenase (lipoamide) beta |
Cytoplasm |
enzyme |
|
1_12 |
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00483215 |
NP_001419 |
ENO1 |
enolase 1, (alpha) |
Cytoplasm |
transcription regulator |
|
|
|
| 2D PAGE |
metabolic signaling |
phenylalanine tyrosine and tryptophan |
IPI00483215 |
NP_001419 |
ENO1 |
enolase 1, (alpha) |
Cytoplasm |
transcription regulator |
|
2_14 |
|
| 2D PAGE |
metabolic signaling |
glycine, serine and threoine metabolism |
IPI00491662 |
NP_001704 |
BHMT |
betaine-homocysteine methyltransferase |
Cytoplasm |
enzyme |
|
2_48 |
|
| 2D PAGE |
metabolic signaling |
methionine metabolism |
IPI00491662 |
NP_001704 |
BHMT |
betaine-homocysteine methyltransferase |
Cytoplasm |
enzyme |
|
1_19 |
|
| 2D PAGE |
metabolic signaling |
arginine and proline metabolism |
IPI00497388 |
NP_001814 |
CKB |
creatine kinase, brain |
Cytoplasm |
kinase |
|
|
|
| 2D PAGE |
metabolic signaling |
urea cycle and metabolism of amino groups |
IPI00497388 |
NP_001814 |
CKB |
creatine kinase, brain |
Cytoplasm |
kinase |
|
2_29 |
|
| 2D PAGE |
metabolic signaling |
arginine and proline metabolism |
IPI00616390 |
NP_001815 |
CKM |
creatine kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D PAGE |
metabolic signaling |
urea cycle and metabolism of amino groups |
IPI00616390 |
NP_001815 |
CKM |
creatine kinase, muscle |
Cytoplasm |
kinase |
|
|
|
| 2D PAGE |
metabolic signaling |
cysteine metabolism |
IPI00495855 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
1_14 |
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00495855 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
propanoate metabolism |
IPI00495855 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
pyruvate metabolism |
IPI00495855 |
NP_002291 |
LDHB |
lactate dehydrogenase B |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
purine metabolism |
IPI00505091 |
NP_009057 |
VCP |
valosin-containing protein |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
citrate cycle |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
3_27 |
|
| 2D PAGE |
metabolic signaling |
glycine, serine and threoine metabolism |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
pyruvate metabolism |
IPI00511568 |
NP_031887 |
DLD |
dihydrolipoamide dehydrogenase (E3 component of pyruvate
dehydrogenase complex, 2-oxo-glutarate complex,
branched chain keto acid dehydrogenase complex) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00490877 |
NP_031959 |
ENO3 |
enolase 3 (beta, muscle) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
phenylalanine tyrosine and tryptophan |
IPI00490877 |
NP_031959 |
ENO3 |
enolase 3 (beta, muscle) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
citrate cycle |
IPI00619732 |
NP_032643 |
MDH2 |
malate dehydrogenase 2, NAD (mitochondrial) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
glyoxylate and dicarboxylate metabolism |
IPI00619732 |
NP_032643 |
MDH2 |
malate dehydrogenase 2, NAD (mitochondrial) |
Cytoplasm |
enzyme |
|
1_16 |
|
| 2D PAGE |
metabolic signaling |
pyruvate metabolism |
IPI00619732 |
NP_032643 |
MDH2 |
malate dehydrogenase 2, NAD (mitochondrial) |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
purine metabolism |
IPI00497989 |
NP_032730 |
NME1 |
non-metastatic cells 1, protein (NM23A) expressed in |
Nucleus |
kinase |
|
|
|
| 2D PAGE |
metabolic signaling |
B-alanine metabolism |
IPI00509410 |
NP_033494 |
DPYSL3 |
dihydropyrimidinase-like 3 |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
pantothenate and CoA biosynthesis |
IPI00509410 |
NP_033494 |
DPYSL3 |
dihydropyrimidinase-like 3 |
Cytoplasm |
enzyme |
|
1_21 |
|
| 2D PAGE |
metabolic signaling |
arginine and proline metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
3_65 |
|
| 2D PAGE |
metabolic signaling |
ascorbate and aldarate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_12 |
|
| 2D PAGE |
metabolic signaling |
B-alanine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
2_50 |
|
| 2D PAGE |
metabolic signaling |
bile acid biosynthesis |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_37 |
|
| 2D PAGE |
metabolic signaling |
butanoate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
2_47 |
|
| 2D PAGE |
metabolic signaling |
fatty acid metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_133 |
|
| 2D PAGE |
metabolic signaling |
glycerolipid metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_83 |
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
8_91 |
|
| 2D PAGE |
metabolic signaling |
histidine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_35 |
|
| 2D PAGE |
metabolic signaling |
lysine degradation |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_51 |
|
| 2D PAGE |
metabolic signaling |
phenylalanine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
2_28 |
|
| 2D PAGE |
metabolic signaling |
propanoate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
3_59 |
|
| 2D PAGE |
metabolic signaling |
pyruvate metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
5_72 |
|
| 2D PAGE |
metabolic signaling |
tryptophan metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_118 |
|
| 2D PAGE |
metabolic signaling |
tyrosine metabolism |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
1_47 |
|
| 2D PAGE |
metabolic signaling |
valine, leucine and isoleucine degradation |
IPI00511179 |
NP_033786 |
ALDH2 |
aldehyde dehydrogenase 2 family (mitochondrial) |
Cytoplasm |
enzyme |
disulfiram |
2_61 |
|
| 2D PAGE |
metabolic signaling |
fructose and mannose metabolism |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
2_47 |
|
| 2D PAGE |
metabolic signaling |
glycolysis/gluconeogenesis |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
Inositol metabolism |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
pentose phosphate pathway |
IPI00490850 |
NP_033787 |
ALDOC |
aldolase C, fructose-bisphosphate |
Cytoplasm |
enzyme |
|
2_33 |
|
| 2D PAGE |
metabolic signaling |
nicotinate and nicotinamide metabolism |
IPI00503999 |
NP_036475 |
NNT |
nicotinamide nucleotide transhydrogenase |
Cytoplasm |
enzyme |
|
1_29 |
|
| 2D PAGE |
metabolic signaling |
purine metabolism |
IPI00504177 |
NP_058054 |
ATP5B |
ATP synthase, H+ transporting, mitochondrial F1 complex, beta
polypeptide |
Cytoplasm |
transporter |
|
|
|
| 2D PAGE |
metabolic signaling |
purine metabolism |
IPI00501538 |
NP_067490 |
AK1 |
adenylate kinase 1 |
Cytoplasm |
kinase |
|
5_262 |
|
| 2D PAGE |
metabolic signaling |
purine metabolism |
IPI00503572 |
NP_109604 |
MYH1 |
myosin, heavy polypeptide 1, skeletal muscle, adult |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
Inositol metabolism |
IPI00512371 |
NP_598803 |
ALDH6A1 |
aldehyde dehydrogenase 6 family, member A1 |
Cytoplasm |
enzyme |
|
3_6 |
|
| 2D PAGE |
metabolic signaling |
propanoate metabolism |
IPI00512371 |
NP_598803 |
ALDH6A1 |
aldehyde dehydrogenase 6 family, member A1 |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
phospholipid degradation |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
1_50 |
|
| 2D PAGE |
metabolic signaling |
prostaglandin and leukotriene metabolism |
IPI00511497 |
NP_663723 |
YWHAZ |
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation
protein, zeta polypeptide |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
methane metabolism |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
1_13 |
|
| 2D PAGE |
metabolic signaling |
phenylalanine metabolism |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
|
|
| 2D PAGE |
metabolic signaling |
prostaglandin and leukotriene metabolism |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
2_76 |
|
| 2D PAGE |
metabolic signaling |
stilbene, coumarine and lignin biosynthesis |
IPI00482908 |
NP_859048 |
PRDX1 |
peroxiredoxin 1 |
Cytoplasm |
enzyme |
|
1_14 |
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