Where is a geodetic software package, used for professional analysis of VLBI data.
Running a VLBI analysis
To do an analysis with Where you only need to specify which analysis pipeline you want to run (i.e. VLBI), as well as the date and any pipeline specific options. For VLBI analysis you need to specify session_code. See the IVS observing program to find possible session codes. A basic Where command for VLBI is
where 2016 12 27 --vlbi --session_code=R1772
This command can be extended by setting any of the many configuration options
available for an analysis. Some of these will be described below. You can also
run where --help
for a quick overview.
Configuration
Every Where analysis is based on a configuration which describes in detail how the analysis is performed, including
- which models are being used,
- which version of each model that is being applied, and
- which parameters are being estimated.
If you run Where like above - without specifying any particular settings - the default configuration is used.
By using the -E
or --edit
option open the configuration in your
standard editor and change it:
where 2016 12 27 --vlbi --session_code=R1772 -E
When you are happy with the configuration, save and close the configuration file the analysis will be executed.
Other useful options
If you want to delete a configuration (and any analysis done) you can use the
-D
or --delete
option:
where 2016 12 27 --vlbi --session_code=R1772 -D
To reset the configuration without deleting any of the previous analysis done,
use the -N
or --new
option:
where 2016 12 27 --vlbi --session_code=R1772 -N
The same option can be combined with the delete option, to immediately start a new configuration:
where 2016 12 27 --vlbi --session_code=R1772 -D -N
Where tries to skip stages that have previously been processed and where none of the dependencies for
that stage has changed. This behaviour can be overridden using the -F
or --force
option.
where 2016 12 27 --vlbi --session_code=R1772 --F
Then all stages will be reprocessed using the existing configuration.
Configuration profiles
The default configuration for VLBI is tuned for analyzing R1/R4 sessions. To
make it easy to analyze other kinds of sessions you can create profiles. This is done by appending __<profilename>
to the configuration parameter that you want to change. There are example profiles created for intensive sessions
and VGOS sessions. Example on use:
where 2020 1 9 -v --session_code=VO0009 --profile=vgos
Comparative analysis
If you want to do several analyses of the same session (for instance to compare different models etc), you need to mark the analysis with their own ids. For instance,
where 2016 12 27 --vlbi --session_code=R1772 --elevation:cut_off=0 --id=zero
where 2016 12 27 --vlbi --session_code=R1772 --elevation:cut_off=3 --id=three
This will run two Where analyses with different elevation cut-offs, stored with
the ids of zero
and three
.
Running many analyses
To analyze many sessions at once, use the where_runner
tool. It has the same
form as the regular where
command, except that it needs two dates: The start
date and end date of the analysis (both inclusive).
where_runner 2016 1 1 2016 12 31 --vlbi
The where_runner
command does not need a --session_code
option. It will run all
kinds of sessions that it finds. If you want to specify that only one or a few
types of sessions should be analyzed, you can still list them with the
--session_types
option:
where_runner 2016 1 1 2016 12 31 --vlbi --session_types=R,CONT
In this example, Where will run all sessions that are of type R1/R4 and CONT and skip all other session types it finds. Session type in this context is a Where specific definition that refers to the first part of the session code that consist of letters (and not numbers). Meaning a session with code R1881 will have type R and a session with code AOV031 will have type AOV.


Interpick'Up is a sample application that demonstrayes how to build apps with Ionic 3, Angular 2, and Node.js


Member Function Documentation
Retrieve the RiakObject to which this link points.
- Parameters:
-
| integer | $r | - The R-value to use. |
- Returns:
- RiakObject
Retrieve the RiakObject to which this link points, as a binary.
- Parameters:
-
| integer | $r | - The R-value to use. |
- Returns:
- RiakObject
Get the bucket name of this link.
- Returns:
- string
Get the key of this link.
- Returns:
- string
Get the tag of this link.
- Returns:
- string
Return true if the links are equal.
- Parameters:
-
- Returns:
- boolean
| RiakLink |
( |
$ |
bucket, |
|
|
$ |
key, |
|
|
$ |
tag = NULL |
|
) |
| |
Construct a RiakLink object.
- Parameters:
-
| string | $bucket | - The bucket name. |
| string | $key | - The key. |
| string | $tag | - The tag. |
Set the bucket name of this link.
- Parameters:
-
| string | $name | - The bucket name. |
- Returns:
- $this
Set the key of this link.
- Parameters:
-
- Returns:
- $this
Set the tag of this link.
- Parameters:
-
- Returns:
- $this
| toLinkHeader |
( |
$ |
client ) |
|
Convert this RiakLink object to a link header string. Used internally.
The documentation for this class was generated from the following file:


Matthew Tse
ESFP. Product Manager & Storyteller
The best product experiences are crafted through human-centered design, data, and strategic engineering. Check out some of my latest work.
The best product experiences are crafted through human-centered design, data, and strategic engineering. Check out some of my latest work.


Error: Changes must be saved before deleting the group.
Error: Revision mismatch. Changes are not applied.


I saw a tweet from Colin Meloy pointing out handclap tweets are "kind of a hassle."
I'm open source on GitHub! All contributions are welcome.


Governor asks court to release 38 Studios grand jury records
PROVIDENCE, R.I. (AP) - Rhode Island Gov. Gina Raimondo is asking the state Supreme Court to release records from the grand jury investigation into the state’s deal with a video game company owned by former Boston Red Sox pitcher Curt Schilling.
The Providence Journal reports Raimondo’s senior counsel Claire Richards argued Thursday in court that Raimondo has standing to bring the case because the company’s collapse cost the state millions of dollars and hindered economic development programs.
Rhode Island invested $75 million in 2010 to lure 38 Studios from Massachusetts. Two years later, the company went bankrupt.
Richards says the public has a right to know how taxpayer money was handled.
Justices expressed concerns about opening grand jury records.
Assistant Attorney General Michael Field argued against the release, urging justices not to undermine secrecy rules.
Sign up for Daily Newsletters
Copyright © 2019 The Washington Times, LLC.
Please read our comment policy before commenting.


Overview
GRIP stands for GRaph Integration Platform. It provides a graph interface on top of a variety of existing database technologies including: MongoDB, Elasticsearch, PostgreSQL, MySQL, MariaDB, Badger, and LevelDB.
Properties of an GRIP graph:
- Both vertices and edges in a graph can have any number of properties associated with them.
- There are many types of vertices and edges in a graph. Two vertices may have many types of edges connecting them, thus reflecting a myriad of relationship types.
- Edges in the graph are directed, meaning they have a source and destination.
GRIP also provides a query API for the traversing, analyzing and manipulating your graphs. Its syntax is inspired by Apache TinkerPop. Learn more here about GRIP and its application for querying the Bio Medical Evidence Graph (BMEG).
Supported Systems
GRIP has three types of drivers:
- Embedded : GRIP has built in graph storage, built using embedded databases. This allows you to quick set graphs for data storage and analysis, without having to configure an external database and connect it to GRIP. This is the default mode if GRIP is started without any configuration. The primarily driver is based on Badger.
- Database Backends : GRIP can utilize a number of different database backends to store graph data. In this mode, GRIP formats the database and manages the data. It provides a full Read/Write API, the same as the Embedded deployment. Supported systems include Mongo, Portgres SQL and Elastic Search. When deployed using Mongo, GRIP will translate GripQL queries into Mongo Aggregation Pipeline queries.
- Plugin Existing Resources : This mode is designed to take advantage of existing data resources, mapping them into a graph framework so they can be accessed using GripQL. This mode is currently read-only.
Future Plans
GRIP is still under active development and there are plans for a number of additional features. These include:
- Batch queries. Ability to submit long running queries to be processed asynchronously and stored for later retrieval.
- Query Caching.
- Query Continuation. Ability to describe a graph query that starts off where another query ended. For example, from batch or cached query and to filtering or a few additional steps.
- Optimized Plugable External Resource API. Adding additional operations, such as ‘joins’ or better filtering, to external resources would allow GRIP to better optimize queries and reduce query time.
- Managed Plugin deployment.


This intention opens a console and executes selected queries. It also attaches the current editor to the console so that later
queries can be executed directly from the code using console 'Execute' action shortcut without switching to the console itself.


coolbutton Behavior
This document describes technologies available in Internet Explorer 5. While we encourage you to evaluate these features and to send us your feedback, please note that these features are subject to change.
The coolbutton behavior inserts a button into a Web page, as a part of the coolbar behavior. It provides a visual cue in the form of an icon and/or a text cue in the form a label indicating which action will be performed. Both the icon and the text can be assigned hover effects for the onmouseout event.
The coolbutton.htc file can be downloaded from the coolbutton sample page.
The most up to date documentation on the coolbutton behavior can be found on the World Wide Web. Use Internet Explorer to navigate to the behaviors library reference.
If you have the latest MSDN-Online Web Workshop CD (formerly Sitebuilder Web Snapshot CD), map a drive to the CD and use Microsoft Windows Explorer to navigate to \workshop\author\behaviors\library\coolbutton\coolbutton.htm.


Powering off Raspberry Pi without proper shutdown could cause SD card corruption and force users to reflash SD cards time to time. By enabling this function NanoDLP listens to GPIO if state of GPIO changed to the required state, it will shutdown the printer during the idle mode and during the print it will stop the printer.
Gradeful Shutdown
To complete power-off it is possible to use Raspberry Pi kernel parameters (config.txt) to let external controller know that Pi is switched off. So it can cut the power completely.
GPIO state changes just after complete Raspberry Pi shutdown.
- Name
- gpio-poweroff
- Info
- Drives a GPIO high or low on poweroff (including halt). Enabling this
overlay will prevent the ability to boot by driving GPIO3 low.
- Load
- dtoverlay=gpio-poweroff,param=val
- Params
- gpiopin
- GPIO for signalling (default 26)
- active_low
- Set if the power control device requires a
high->low transition to trigger a power-down.
Note that this will require the support of a
custom dt-blob.bin to prevent a power-down
during the boot process, and that a reboot
will also cause the pin to go low.
- input
- Set if the gpio pin should be configured as
an input.
- export
- Set to export the configured pin to sysfs
- timeout_ms
- Specify (in ms) how long the kernel waits for
power-down before issuing a WARN (default 3000).
- Example
- dtoverlay=gpio-poweroff,gpiopin=20


Hilde Osland Stuns In Sheer-Paneled Yoga Pants: ‘Gotta Love It’
November 21, 2019
Hilde Osland Stuns In Sheer-Paneled Yoga Pants: ‘Gotta Love It’
Norwegian bombshell Hilde Osland stunned her fans on Thursday morning by posting a mega seven-picture update where she sizzled in a pretty, skintight yoga set.
The top part of the set consisted of a light mauve-colored sports bra. The front panels were cut into a triangle shape, almost like a bikini top. They were joined together by a stretchy see-through mesh fabric which could not conceal the curve of Hilde’s ample cleavage. The mesh extended up to create a halter-style neckline, and two additional straps joined at the bust to create a trendy crisscross for a final detail.
She paired it with matching yoga pants that featured a high cut that cinched at the waist, emphasizing her hourglass figure. Moreover, the skintight spandex material hugged her hips and her famously perky derriere. Down the side of the pants was another sheer mesh panel — like in the top — which exposed skin all down Hilde’s long and lean legs, much to her fans’ delight.
Hilde accessorized with a pair of gold hoop earrings and a bracelet, and wore chunky white sneakers to complete her look. She kept her makeup in a pretty peachy palette, with a slight brush of apricot eyeshadow, blush, and a touch of lip tint. Her long blond locks were styled into soft waves and cascaded down her back.
The setting was a street that boasted stunning flowering trees, and the blossoms perfectly matched Hilde’s attire — a fact the Scandinavian stunner mentioned in her caption.
In the first photo, Hilde gave the camera a side view of her fantastic figure as she attempted to tame her windswept hair. The second shot featured a front-facing pose, with Hilde running her hand through her hair while giving the camera a sweet smile.
Third and fourth pictures were full-body shots. One was a view of Hilde from behind to showcase her derriere, and the other was another side view.
Fifth and sixth featured a slightly upwards angle of the beachy beauty, one from the front and another from behind.
In the last picture, Hilde posed by cheekily looking over her shoulder.
Within under half an hour, fans already awarded the update around a whopping 14,000 likes and more than 350 comments.
Loading...
“You are incredibly beautiful. Picture perfect every time,” one fan raved.
“You just made my day,” added another, with two red hearts.
“Perfect 10,” concluded a third, with three fire emoji.
Hilde is often featured in athleisure wear and has often discussed her passion for fitness. Her killer body certainly shows the results of her hard work, and just yesterday she flaunted her taut midriff in a belly-baring crop top-and-skirt set, as previously covered by The Inquisitr.


--- layout: post title: "My Week in Review" date: 2018-02-04 13:30:00 +0000 tags: image: https://s3.amazonaws.com/audreywatters/2018-02-04-books.jpg imagecredits: https://www.flickr.com/photos/michidan/4460186035 ---
Icon credits: The Noun Project


---
layout: post
title: Isthmus | The Daily Page - Scoops for the week of Nov. 30- Dec. 7
date: '2007-11-30T09:58:00.001-06:00'
author: Tom Ray
tags:
modified_time: '2007-11-30T09:58:50.031-06:00'
blogger_id: tag:blogger.com,1999:blog-11319466.post-5547053050736708471
blogger_orig_url: http://www.lorenzosmusic.com/2007/11/isthmus-daily-page-scoops-for-week-of.html
---
An excerpt from a recent Isthmus article about our netcasts.
Lorenzo's Music are posting weekly netcasts to their website (www.lorenzosmusic.com) to unveil their forthcoming album, one song at a time. But the videos don't feature the band performing.Isthmus | The Daily Page - Scoops for the week of Nov. 30- Dec. 7
"I'm a fan of old movies and retro commercials," explains the local rock band's lead vocalist, Tom Ray. "So I searched some public domain archives and chose a film."


Internet, Movies, Reading, Dancing, Karaoke, Baseball, Language, Culture, History of Communism, Philosophy, Singing/Writing Music, Running, Finding New Food, Weight Lifting, Hiking, WWI Aviation, Travel, Building alternate communities
Music
Bands: Beatles, Superdrag, Jackson 5, Weezer, Sex Pistols, The Carpenters, Vain, Radiohead, Teenage Fanclub, Rocket from the Crypt, Pitchfork, Oasis, Rialto, Supergrass, Travis, The Doors, Cheap Trick, Simple Plan, Alice Cooper, KISS, A*TEENS, The Beach Boys, The Velvet Underground, Journey
Solo Artists: Billy Joel, Bruce Springsteen, Elvis, Brendan Benson, David Bowie, Rick Springfield, Barry Manilow, Paul Stanley Solo Album, Bob Dylan, Rod Stewart
Singers: Michael Jackson (age 14 & under), Karen Carpenter, Whitney Houston (particularly The Bodyguard soundtrack), George Michael, Louie Louie, Coco Lee, Robin Zander, Frank Sinatra, Steve Perry, Gerard Way
Albums: Appetite for Destruction - Guns & Roses; Life - The Cardigans; A Hard Day's Night - The Beatles; Dookie - Green Day; Blue - Weezer; One Missisipi - Brendan Benson; Two Steps from the Move - Hanoi Rocks; Led Zeppelin I, The Doors, In The Valley of Dying Stars - SuperDrag; Survivor When Seconds Count - Rick Springfield, Working Class Dog
Instruments: The Er Hu, Piano, certain guitar tones (Rocket from the Crypt, Sex Pistols, Rolling Stones)
Films: Lawrence of Arabia, Ben Hur, Patton, Spartacus, Gandhi, The 10 Commandments, Apocalypse Now, Beauty & The Beast (the cartoon), Thin Red Line, Titanic, Gladiator, The Patriot, Breakfast at Tiffanys, Un Coeur en Hiver, To Live, Happy Times, The Road Home, Not One Less, Ju Dou, Red Sorghum, The Empire of the Sun, Gone With the Wind, The Godfather, 2001, Clockwork Orange, Blade Runner, Deer Hunter, Mean Streets, Grease, Urban Cowboy, Saturday Night Fever, The Sound of Music, Copland, Xiu Xiu, Dances With Wolves
Directors: Kubrick, Francis Copolla, Zhang Yimou, Anh Hung Tran, Steven Spielberg
Television
Tuned out. Except for SF Giants. I rented Band of Brothers and liked that.
Books
Nietzsche, George Orwell, Milan Kundera, Laurens van der Post


Let the user pick the language and swipe next. If you want, you can translate the Tutorial too!
Ionic Framework is an open source SDK that enables developers to build high quality mobile apps with web technologies like HTML, CSS, and JavaScript.


Welcome to Marcel's Landing Site
Sprint 1
Sprint 2
Sprint 3
Sprint 4
Sprint 5
Sprint 6
Getting to know you site:
Resume:
Map Mania version 1
Map Mania version 2
JSON AJAX TUTORIAL
JSON Contact Info
Mustang Version 1
Final Project Proposal
Mustang Version 2


1-year-old boy drowns in river in Malawai , Gau
by Vijay NarayanA one-year-old boy drowned in a river in Malawai, Gau on Saturday afternoon.
The victim's mother noticed the child missing from their home and upon searching, found him floating in a nearby river.
He was rushed to the Nacavanadi Nursing Station where attempts to revive him proved futile.
Police investigations continue.
The drowning toll currently stands at 33 compared to 40 for the same period last year.


{% extends "base.html" %} {% block title %}Islandr - Page Not Found{% endblock %} {% block page_content %}
You don't have the permission to access the requested resource. It is either read-protected or not readable by the server.


target variable:
>
numeric expressions :
+
<
>
7
8
9
-
<=
>=
4
5
6
x
=
<>
1
2
3
%
&
|
0
.
xy
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)
delete
commit
cancel


I'm a passionate individual breaking into Front-End development industry. Looking to offer my skills in my ability to learn fast while maintaining an eye for detail.
I've always been that tech savvy guy that could figure out why something wasn't working quite right and come forward with a solution.
Hoping to become a part of a team that is motivated and positive while learning what I can from everyone I work with to become a great developer of web applications.
Fan made site of a new favorite game of mine. I pulled together various details from the game that I felt would give people a sense of familiarty while also informing people of various aspects of the game.
View ProjectI love to swim but always have a fear of swimming in open water. I hope to one day learn to scuba dive to overcome that fear, so I've put together a simple one page attribute to making that happen.
View Project


Get help buying. Chat now or call 1-800-MY-APPLE.
Touch Bar and Touch ID, 2.8GHz Processor, 256GB Storage
2.8GHz quad-core 7th-generation Intel Core i7 processor
Turbo Boost up to 3.8GHz
16GB 2133MHz LPDDR3 memory
256GB SSD storage
Radeon Pro 555 with 2GB memory
$2,399.00


Clicking Catalog
Changes tab and shows catalog page. But pageInit is called only once when application is loaded.
Clicking Component
Shows component page and pageInit is called every time clicked. But tab is remains on home and page is overlaying Home.


Upcoming Events
Philmont Scout Ranch: Trek Colfax County, New Mexico 2022 Spots Open!
- Pancake Breakfast: Applebee's Hughes Rd Madison, April 30
- Grimes Canoe Base: May 13-15
- Eagle Court of Honor: May 15, 3:00pm
- Summer Camp: Camp Comer, June 5 - 11
- Philmont Backpacking Trip: June 16 - 29
- Deep Creek: North Carolina, July 8 - 10


AYERS, Barbara
Wednesday, March 07, 2007
Obituary
: AYERS, Barbara - At Marshall Gowland Manor, Sarnia, on Monday, March 5, 2007. BARBARA AYERS (nee Robbins), 67 years, of Sarnia and formerly of ... [
View
]


MailServer implements a data model for mail servers configuration.
Default constructor
public Void MailServer()
Initializes a new instance of MailServer.
public Void MailServer(id)
| Name | Type | Summary |
|---|---|---|
| id | String | Object Id. |
Gets whether the model validation must be enforced.
public Boolean EnforceModelValidation { get; }
Address from which mails are sent.
public String From { get; set; }
Display name for the sending address.
public String FromName { get; set; }
The identification of this MailServer.
public String Id { get; set; }
Server name or IP address.
public String Name { get; set; }
Mail sending port.
public Int32 Port { get; set; }
Whether the server requires SSL.
public Boolean RequiresSsl { get; set; }
Whether the server uses authentication.
public Boolean UseAuthentication { get; set; }
User name for use with authentication.
public String UserName { get; set; }
Password of the user for use with authentication.
public String UserPassword { get; set; }
Checks whether other is equal to this object.
public Boolean Equals(other)
| Name | Type | Summary |
|---|---|---|
| other | MailServer | The object to check equality to. |
Checks whether obj is equal to this object.
public Boolean Equals(obj)
| Name | Type | Summary |
|---|---|---|
| obj | Object | The object to compare this object to. |
Serves as the default hash function.
public Int32 GetHashCode()
Initializes a new instance of MailServer and loads it data from the underlaying repository.
public MailServer Load(id)
| Name | Type | Summary |
|---|---|---|
| id | String | Object Id. |
Initializes a new instance of MailServer and loads it data from the underlaying repository asyncronously.
public Task<MailServer> LoadAsync(id)
| Name | Type | Summary |
|---|---|---|
| id | String | Object Id. |
Sends a message by mail.
public Task SendAsync(message)
| Name | Type | Summary |
|---|---|---|
| message | Message | The message to send. |
| Type | Summary |
|---|---|
| ArgumentNullException | Thrown when message is null. |
| SendException | Thrown when an error occours while sendind the message. |
Returns a textual representation of a MailServer.
public String ToString()
Checks whether the object is valid for saving.
public Void Validate()
| Type | Summary |
|---|---|
| ValidationException | Thrown when the object is not valid. |


What is the Testability Explorer
Testability-explorer is a tool which analyzes Java bytecode and computes how difficult it will be to write unit tests for the code. It attempts to help you quantitatively determine how hard your code is to test, and where to focus to make it more testable.
Testability Explorer can be used:
- As a learning tool which flags causes of hard to test code with detailed breakdown of reasons.
- To identify hard to test hair-balls in legacy code.
- As part of your code analysis-toolset.
- As a tool which can be added into continuous integration that can enforce testable code.
Currently the tool computes:
- Non-Mockable Total Recursive Cyclomatic Complexity. Cyclomatic Complexity is a measure of how many different paths of execution are there in the code. It is computed, by counting the if, while, and case as branching primitives. It is recursive because cost of the method as well as any methods it calls are counted. It is total because cost of object construction as well as any static initializations are counted. And finally, it is non-mockable because any code which can be mocked out in test is not counted as part of the cost. This means that the score is based on the amount of complex code that cannot be mocked out in a unit test.
- Global Mutable State. Counts the number of fields which are globally reachable by the class under test and which are mutable. Mutable global state makes testing difficult as tests are not isolatable, the global state needs to be set up and cleared between tests.
- Law of Demeter. This is the principle that calling methods on objects you get from other collaborators is trouble, instead, the collaborator should call that method itself. It makes testing harder because your mocks must expose some internal state through these methods.
For more information about testability explorer, please visit http://code.google.com/p/testability-explorer
For a demo of testability-explorer in action see http://testabilityexplorer.org/report.


Rails Cast for twitter bootstrap:
Note During install your can specify whether you want a fixed or fluid layout
LESS is a CSS precessor : to get LESS working with rails you need the help of some gems
I can download the source here. This is the preferred code not, this one.
Change Gemfile
1 2 3 |
|
Install Twitter Bootstrap
1 2 3 |
|
A file that was generated is: app/assets/stylesheets/bootstrap_and_override.css.less This is where I would do the bulk of the customization - including if padding is needed between the body and the nav bar…
1 2 3 |
|
Layout fixed makes it 940px and fluid makes it full screen. Both are responsive though.
When I generate new resources
1 2 3 |
|
Without the 3rd line it looks terrible so remember to run it!
Further reading is here.
When I’m ready for it, Bates does a follow up rails cast on more advanced twitter bootstrap.
NOTE: We went over twitter bootstrap in lecture 6 of ROR spring


Mingshou Monday
|
On Monday, one of the characters in the Japanese anime "xiamu Youren Zhang" was a popular actor and demon killer. Part time actor work, and the protagonist Xia muguizhi can see monsters, but hate monsters. After being influenced by summer eyes, it is no longer so annoying. He is very concerned about Xia mu.
|
Character setting
|
I often wear a fisherman's hat when I go out, a shirt and a suit most of the time, and a T-shirt occasionally when I am at home. My special skill is to shine a dazzling star and always keep a modest smile. Wearing glasses with no degree, you can't wear them at home (glasses are for seeing the world of monsters through the glass). There is a lizard like mole on the body (invisible to ordinary people, it's a monster)
Back to role introduction
|
|
|
| Xia Mu You Ren Zhang is a cartoon work of Luchuan. The style of cartoon is slightly different from that of animation. Xia Mu Guizhi got those contracts from the relics of his grandmother Xia Mu Lingzi; Friends account;, He decided to return the names of the monsters in his friend's account one by one. Around xiamu, all kinds of monsters began to gather & middot& middot;& middot;& middot;& middot;& middot; Xia muguizhi, a young man who can see monsters, tells us strange, sad, nostalgic and touching stories together with the monster spots on the appearance of Zhaocai cat. |
|
|


Tweets¶
Create, Read, Delete¶
var tweet = await userClient.Tweets.PublishTweetAsync("My first tweet with Tweetinvi!");
var publishedTweet = await client.Tweets.GetTweetAsync(tweet.Id);
await userClient.Tweets.DestroyTweetAsync(tweet);
Tweets are not just text, here are various additional metadata you can add to your tweets.
var fullTweet = await userClient.Tweets.PublishTweetAsync(new PublishTweetParameters("A complex tweet from Tweetinvi")
{
Coordinates = new Coordinates(37.7821120598956, -122.400612831116),
DisplayExactCoordinates = true,
TrimUser = true,
PlaceId = "3e8542a1e9f82870",
PossiblySensitive = true,
});
Extended Tweets¶
Tweets are created by default with
tweet_mode
set toextended
. You can change this in all parameters associated with tweets.
Learn more about extended mode
Retweets¶
// publish a retweet
var retweet = await userClient.Tweets.PublishRetweetAsync(tweet);
// destroy the retweet
await userClient.Tweets.DestroyRetweetAsync(retweet);
// get retweeters
var retweeters = await client.Tweets.GetRetweeterIdsAsync(tweet);
// or
var retweeterIdsIterator = client.Tweets.GetRetweeterIdsIterator(tweet);
Replies¶
// reply to a tweet
var tweet = await userClient.Tweets.GetTweetAsync(1313034609437880320);
var reply = await userClient.Tweets.PublishTweetAsync(new PublishTweetParameters("@" + tweet.CreatedBy + " here is a great reply")
{
InReplyToTweet = tweet
});
// remove the same way as you would delete a tweet
await userClient.Tweets.DestroyTweetAsync(reply);
To send a reply, you must prefix the tweet text with a @username
.
Not doing so will result in the tweet to be sent as a normal tweet and not a reply.
Publish with Media¶
You can attach images, gif and videos that you uploaded to your tweets.
With an image¶
var tweetinviLogoBinary = File.ReadAllBytes("./tweetinvi-logo-purple.png");
var uploadedImage = await userClient.Upload.UploadTweetImageAsync(tweetinviLogoBinary);
var tweetWithImage = await userClient.Tweets.PublishTweetAsync(new PublishTweetParameters("Tweet with an image")
{
Medias = { uploadedImage }
});
With a video¶
var videoBinary = File.ReadAllBytes("./video.mp4");
var uploadedVideo = await userClient.Upload.UploadTweetVideoAsync(videoBinary);
// IMPORTANT: you need to wait for Twitter to process the video
await userClient.Upload.WaitForMediaProcessingToGetAllMetadataAsync(uploadedVideo);
var tweetWithVideo = await userClient.Tweets.PublishTweetAsync(new PublishTweetParameters("tweet with media")
{
Medias = { uploadedVideo }
});
Favorites¶
// favorite
await userClient.Tweets.FavoriteTweetAsync(tweet);
// remove
await userClient.Tweets.UnfavoriteTweetAsync(tweet);
// get user favourites
var favouritedTweets = await userClient.Tweets.GetUserFavoriteTweetsAsync("tweetinviapi");
// or
var favoriteTweetsIterator = userClient.Tweets.GetUserFavoriteTweetsIterator("tweetinviapi");
OEmbed Tweets¶
Twitter can generate HTML for you so that you can display a tweet on your website as it would appear on twitter.
You can generate oembed tweets from Tweetinvi. If you want to learn more please read Twitter documentation.
var oEmbedTweet = await client.Tweets.GetOEmbedTweetAsync(tweet);


2956 Bernice Road Ste 1E
Lansing , IL, 60438
773-368-7594
Tuesday 9:00am-6:00pm Wednesday 9:00am-6:00pm Thursday 9:00am-6:00pm Friday 9:00am-6:00pm Saturday 9:00am-6:00pm
Tuesday 9:00am-6:00pm
Wednesday 9:00am-6:00pm
Thursday 9:00am-6:00pm
Friday 9:00am-6:00pm
Saturday 9:00am-6:00pm


{{>_header}}
Find out how nodes are listed on the library and how you can get yours included.
Add a new example flow to the library for others to learn from.
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|
Exodus
6.36
|
#include "exodusII.h"
#include "exodusII_int.h"
#include "netcdf.h"
#include <stdio.h>
#include <stdlib.h>
Macros | |
| #define | NC_FLOAT_WORDSIZE 4 |
| #define | NC_DOUBLE_WORDSIZE 8 |
Functions | |
| struct ex_file_item * | ex_find_file_item (int exoid) |
| int | ex_conv_ini (int exoid, int *comp_wordsize, int *io_wordsize, int file_wordsize, int int64_status, int is_parallel, int is_mpiio, int is_pnetcdf) |
| void | ex_conv_exit (int exoid) |
| nc_type | nc_flt_code (int exoid) |
| int | ex_int64_status (int exoid) |
| int | ex_set_int64_status (int exoid, int mode) |
| int | ex_set_option (int exoid, ex_option_type option, int option_value) |
| int | ex_comp_ws (int exoid) |
| int | ex_is_parallel (int exoid) |
Variables | |
| static struct ex_file_item * | file_list = NULL |
this file contains code needed to support the various floating point word size combinations for computation and i/o that applications might want to use. See the netcdf documentation for more details on the floating point conversion capabilities.
netCDF supports two floating point word sizes for its files:
| #define NC_DOUBLE_WORDSIZE 8 |
| #define NC_FLOAT_WORDSIZE 4 |
| int ex_comp_ws | ( | int | exoid | ) |
ex_comp_ws() returns 4 (i.e. sizeof(float)) or 8 (i.e. sizeof(double)), depending on the value of floating point word size used to initialize the conversion facility for this file id (exoid).
| exoid | integer which uniquely identifies the file of interest. |
| void ex_conv_exit | ( | int | exoid | ) |
ex_conv_exit() takes the structure identified by "exoid" out of the linked list which describes the files that ex_conv_array() knows how to convert.
| exoid | integer which uniquely identifies the file of interest. |
| int ex_conv_ini | ( | int | exoid, |
| int * | comp_wordsize, | ||
| int * | io_wordsize, | ||
| int | file_wordsize, | ||
| int | int64_status, | ||
| int | is_parallel, | ||
| int | is_mpiio, | ||
| int | is_pnetcdf | ||
| ) |
ex_conv_ini() initializes the floating point conversion process.
| exoid | an integer uniquely identifying the file of interest. |
| comp_wordsize | compute floating point word size in the user's code. a zero value indicates that the user is requesting the default float size for the machine. The appropriate value is chosen and returned in comp_wordsize, and used in subsequent conversions. a valid but inappropriate for this parameter cannot be detected. |
| io_wordsize | the desired floating point word size for a netCDF file. for an existing file, if this parameter doesn't match the word size of data already stored in the file, a fatal error is generated. a value of 0 for an existing file indicates that the word size of the file was not known a priori, so use whatever is in the file. a value of 0 for a new file means to use the default size, an NC_FLOAT (4 bytes). when a value of 0 is specified the actual value used is returned in io_wordsize. |
| file_wordsize | floating point word size in an existing netCDF file. a value of 0 should be passed in for a new netCDF file. |
| int64_status | the flags specifying how integer values should be stored on the database and how they should be passes through the api functions. See #FileVars for more information. |
word size parameters are specified in bytes. valid values are 0, 4, and 8:
| struct ex_file_item* ex_find_file_item | ( | int | exoid | ) |
| int ex_int64_status | ( | int | exoid | ) |
| int ex_is_parallel | ( | int | exoid | ) |
ex_is_parallel() returns 1 (true) or 0 (false) depending on whether the file was opened in parallel or serial/file-per-processor mode. Note that in this case parallel assumes the output of a single file, not a parallel run using file-per-processor.
| int ex_set_int64_status | ( | int | exoid, |
| int | mode | ||
| ) |
| int ex_set_option | ( | int | exoid, |
| ex_option_type | option, | ||
| int | option_value | ||
| ) |
| nc_type nc_flt_code | ( | int | exoid | ) |
|
static |


State health officials launch investigation into E. coli infections
by Logan RudeMADISON, Wis. - State Department of Health Services officials are investigating a significant increase in reported cases of E. coli in the state, according to a news release.
Officials said they are working with local health departments to interview sick people in an attempt to find commonalities in their behavior that might be the cause of the outbreak.
According to the release, symptoms of an E. coli infection vary, but can include stomach cramps, diarrhea and vomiting. Roughly 5% to 10% of people who are diagnosed can develop a life-threatening complication that can cause kidney failure and extended periods of hospitalization, the release said.
DHS officials said you can prevent E. coli by washing your hands before eating or preparing food and after using the restroom. Officials also recommend staying home from work, school or day care when you are sick.


Pion WebRTC - Record and Playback as Stream Example
Record your audio/video on the server
Stream back your recordings


This page contains webassembly and javascript content, please enable javascript in your browser.
Rustmen - a Micemen tribute


mongoc_socket_t
Portable socket abstraction
Synopsis
#include <mongoc.h> typedef struct _mongoc_socket_t mongoc_socket_t
Synopsis
This structure provides a socket abstraction that is friendlier for portability than BSD sockets directly. Inconsistencies between Linux, various BSD's, Solaris, and Windows are handled here.


Why The Colts Will Score More Than The Other Guys - Steelers Edition
by jgerbigWho: The Indianapolis Colts vs the Pittsburgh Steelers.
What: Week 9 of the 2019 NFL season.
Where: Ketchup Field, Pittsburgh, PA.
When: 1 PM Eastern, Sunday, November 3rd. Daylight saving time goes into effect at 2 this morning, so everyone’s going to be griping about that. TV: CBS. Once again we get their #2 crew of Ian Eagle and Dan Fouts. Hopefully Rock Ya-Sin gives them something else to talk about this week. (He was penalized 4 times during that sentence).
Why the Colts will score more than the other guys:
1. Luck
No, no, no, not that guy. SMH. “To wait for luck is the same as waiting for death” – Japanese proverb. Kinda like reading this article.
I had something nifty all planned out for this space, then things just went all astray, and upside down and back and forth and all of that stuff.
At about 3 this morning (game day), I stopped off at the inconvenience store, my mind lost in thought over the events of the night. I parked on the side of the building, same as always, and as I rounded the corner I saw a disheveled looking man with a full beard, and wearing a disheveled looking Colts hoodie. I have no idea why he was sitting there, but as I passed him, we made eye contact and with a wink he held up a sign reading “I gave my heart to this team!”
Marlon Mack is going to run over these fools.  And so are the people who wave them.
2. Why do I even try
Jess is back this week and dropped a gem (?):
“Because unlike the other famous Rudolph, Mason’s nose isn’t a beacon of light, leading teams to eternal holiday glory.”
 I’m just the messenger.
3. Throwback Sunday
A throwback to the days when life was different
Whew.
Colts 21, Steelers 17


diagrams match assignment requirements OKAY
diagrams are properly written/drawn OKAY
EXECUTION
test plan exercises assignment requirements OKAY
code satisfies test plan OKAY
code has no bugs when run on: Chrome, Firefox, IE, Safari, Android, iOS (choose any 3) OKAY
SPECIFICATIONS
code satisfies assignment requirements OKAY
code is pushed to github OKAY
code is indented properly OKAY
code is organized modularly OKAY
copied code is properly cited OKAY
files are named properly OKAY
files are saved in proper subdirectories OKAY
COMMENTS
comments are appropriately thorough OKAY
comments are clear and meaningful OKAY
comments neither obfuscate nor or state the obvious OKAY
comments are properly formatted OKAY
EXTRA
I did three extra widgets


A version control system maintains an organized set of all the versions of files that are made over time. Version control systems allow people to go back to previous revisions of individual files, and to compare any two revisions to view the changes between them. In this way, version control keeps a historically accurate and retrievable log of a file's revisions. More importantly, version control systems help several people (even in geographically disparate locations) work together on a development project over the Internet or private network by merging their changes into the same source repository.
Because CVS is a vastly powerful tool, the learning curve might seem formidable. Certainly there are plenty of books and web sites offering comprehensive CVS knowledge bases (many good sources are referenced at the bottom of this site's main CVS page). However, it is not necessary to digest an entire tome to be able to incorporate CVS into your software development practices immediately and effectively.
CVS allows you to work within your own development cycle while keeping track of the project's overall development cycle:
- You begin working on a project by obtaining your own working copy of files, known as checking out the project repository or modules, individual groups of project source files.
- You make your contributions to the project by modifying these files and creating new files.
This part of the cycle doesn't involve cvs directly. You modify your working copies of project files using a file editor on your local machine. You can save and compile your edited files to test how your changes affect the particular project module you are working in without affecting anyone else's work on those same project files. Nothing you do affects other project participants until you merge your changes into the project repository.
- You test and tweak your latest changes in your own workspace to make sure these work without breaking or corrupting the overall project.
- Finally, you contribute back or check in your changes to the main or "top" body of project files, merging your work with the most recent working version known in CVS terminology as the head.
Committing your changes to merge with other developers' work is the most powerful aspect of CVS, but that power also makes it the most critical aspect. It's possible to get confused and accidentally overwrite someone else's changes or your own. Your contributed changes invariably will conflict with someone else's at some point. Understanding how and when to update your working copies and how to resolve merge conflicts are two particularly critical aspects of using CVS in collaborative development projects.
This copy-modify-merge cycle is repeated throughout the life of the project by all contributing developers. CVS enables everyone to work on project files simultaneously, to stay up to date on the latest changes contributed by others, and to test how their own changes affect the overall project without interrupting other developers' cycles.
If you are new to CVS, learn more at:
CVS for New Users (an article)
An Overview of CVS (from the online version of Karl Fogel's book Open Source Development with CVS)
Back to main Help index


TARGRETIN- bexarotene gel
Ligand Pharmaceuticals Inc.
Targretin® (bexarotene) gel 1% contains bexarotene and is intended for topical application only. Bexarotene is a member of a subclass of retinoids that selectively activate retinoid X receptors (RXRs). These retinoid receptors have biologic activity distinct from that of retinoic acid receptors (RARs).
The chemical name is 4-[1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl] benzoic acid, and the structural formula is as follows:
Bexarotene is an off-white to white powder with a molecular weight of 348.48 and a molecular formula of C24H28O2. It is insoluble in water and slightly soluble in vegetable oils and ethanol, USP.
Targretin® gel is a clear gelled solution containing 1.0% (w/w) bexarotene in a base of dehydrated alcohol, USP, polyethylene glycol 400, NF, hydroxypropyl cellulose, NF, and butylated hydroxytoluene, NF.
Bexarotene selectively binds and activates retinoid X receptor subtypes (RXRα, RXRβ, RXRγ). RXRs can form heterodimers with various receptor partners such as retinoic acid receptors (RARs), vitamin D receptor, thyroid receptor, and peroxisome proliferator activator receptors (PPARs). Once activated, these receptors function as transcription factors that regulate the expression of genes that control cellular differentiation and proliferation. Bexarotene inhibits the growth in vitro of some tumor cell lines of hematopoietic and squamous cell origin. It also induces tumor regression in vivo in some animal models. The exact mechanism of action of bexarotene in the treatment of cutaneous T-cell lymphoma (CTCL) is unknown.
Plasma concentrations of bexarotene were determined during clinical studies in patients with CTCL or following repeated single or multiple-daily dose applications of Targretin® gel 1% for up to 132 weeks. Plasma bexarotene concentrations were generally less than 5 ng/mL and did not exceed 55 ng/mL. However, only two patients with very intense dosing regimens (> 40% BSA lesions and QID dosing) were sampled. Plasma bexarotene concentrations and the frequency of detecting quantifiable plasma bexarotene concentrations increased with increasing percent body surface area treated and increasing quantity of Targretin® gel applied. The sporadically-observed and generally low plasma bexarotene concentrations indicated that, in patients receiving doses of low to moderate intensity, there is a low potential for significant plasma concentrations following repeated application of Targretin® gel. Bexarotene is highly bound (>99%) to plasma proteins. The plasma proteins to which bexarotene binds have not been elucidated, and the ability of bexarotene to displace drugs bound to plasma proteins and the ability of drugs to displace bexarotene binding have not been studied (see PRECAUTIONS: Protein Binding). The uptake of bexarotene by organs or tissues has not been evaluated.
Four bexarotene metabolites have been identified in plasma following oral administration of bexarotene: 6- and 7-hydroxy-bexarotene and 6- and 7-oxo-bexarotene. In vitro studies suggest that cytochrome P450 3A4 is the major cytochrome P450 responsible for formation of the oxidative metabolites and that the oxidative metabolites may be glucuronidated. The oxidative metabolites are active in in vitro assays of retinoid receptor activation, but the relative contribution of the parent and any metabolites to the efficacy and safety of Targretin® gel is unknown.
The renal elimination of bexarotene and its metabolites was examined in patients with Type 2 diabetes mellitus following oral administration of bexarotene. Neither bexarotene nor its metabolites were excreted in urine in appreciable amounts.
Elderly, Gender, Race: Because of a large number of immeasurable plasma concentrations (< 1ng/mL), any potential pharmacokinetic differences between Special Populations could not be assessed.
Pediatric: Studies to evaluate bexarotene pharmacokinetics in the pediatric population have not been conducted (see PRECAUTIONS: Pediatric Use).
Renal Insufficiency: No formal studies have been conducted with Targretin® gel in patients with renal insufficiency. Urinary elimination of bexarotene and its known metabolites is a minor excretory pathway (<1% of an orally administered dose), but because renal insufficiency can result in significant protein binding changes, pharmacokinetics may be altered in patients with renal insufficiency (seePRECAUTIONS: Renal Insufficiency).
Hepatic Insufficiency: No specific studies have been conducted with Targretin® gel in patients with hepatic insufficiency. Because less than 1% of the dose of oral bexarotene is excreted in the urine unchanged and there is in vitro evidence of extensive hepatic contribution to bexarotene elimination, hepatic impairment would be expected to lead to greatly decreased clearance (see PRECAUTIONS: Hepatic Insufficiency).
No formal studies to evaluate drug interactions with bexarotene or Targretin® gel have been conducted. Bexarotene oxidative metabolites appear to be formed through cytochrome P450 3A4. Drugs that affect levels or activity of cytochrome P450 3A4 may potentially affect the disposition of bexarotene. Concomitant gemfibrozil was associated with increased bexarotene concentrations following oral administration of bexarotene.
Targretin® gel was evaluated for the treatment of patients with early stage (Stage IA-IIA) CTCL in one multicenter, open-label, clinical trial as well as in a Phase I-II program (dose-seeking trials with different response criteria than the multicenter trial). These clinical studies enrolled a total of 117 patients.
In the multicenter, open-label clinical trial, Targretin® gel was evaluated for the treatment of patients with early stage CTCL who were refractory to, intolerant to, or reached a response plateau for at least six months on at least two prior therapies. The study was conducted in the U.S., Canada, Europe, and Australia and enrolled a total of 50 patients; 46% of these patients were male, 80% were Caucasian, and the median age was 64 years (range 13 to 85).
Targretin® gel was also evaluated for the treatment of patients with CTCL in a U.S. Phase I-II program involving patients with early stage CTCL. This program enrolled a total of 67 patients; 55% of these patients were male, 85% were Caucasian, and the median age was 61 years (range 30 to 87).
In the multicenter, open-label clinical trial, considering prior systemic, irradiation, and topical treatments, patients had been exposed to a median of 3 prior therapies (range 2-7). All patients failed at least two treatments; the majority (68%) of patients were either refractory to two or more therapies, or were refractory to one therapy and intolerant to at least one therapy.
Patients were treated with Targretin® gel 1% for a planned 16-week period with an option to continue provided that no unacceptable toxicity was occurring.
Tumor response was assessed in the multicenter study by observation of up to five baseline-defined index lesions using a Composite Assessment of Index Lesion Disease Severity (CA). This endpoint was based on a summation of the grades, for all index lesions, of erythema, scaling, plaque elevation, hypopigmentation or hyperpigmentation, and area of involvement. New cutaneous lesions or tumors and extracutaneous disease manifestations were not considered in response or disease progression assessments.
All tumor responses required confirmation over at least two assessments separated by at least four weeks. A partial response was defined as an improvement of at least 50% in the index lesions. A complete clinical response required complete disappearance of the index lesions, but did not require confirmation by biopsy.
Targretin® gel produced an overall response rate of 26% (13/50) with a corresponding exact 95% confidence interval from 14.6% to 40.3% by the Composite Assessment of Index Lesion Severity. For the Stage IA and IB patients, the response rate was 28% (13/47) with a corresponding exact 95% confidence interval from 15.6% to 42.6%. For the Stage II patients the response rate was 0% (0/3). Two percent of patients (1/50) had a clinical complete response. The median time to best response on the Composite Assessment of Index Lesion Severity (n=13) was 85 days (range: 36-154).
The rate of relapse in responding patients by the Composite Assessment of Index Lesion Severity was 23% (3/13) over a median observation period of 149 days (range 56-342). Fourteen patients developed new lesions in untreated areas (14/50; 28%). Four patients developed clinically abnormal lymph nodes (≥ 1cm diam) (4/50; 8%). One patient developed a cutaneous tumor (1/50; 2%).
The Phase I-II program (dose-seeking trials with different response criteria than the multicenter trial) was supportive of the multicenter study results.
Targretin® (bexarotene) gel 1% is indicated for the topical treatment of cutaneous lesions in patients with CTCL (Stage IA and IB) who have refractory or persistent disease after other therapies or who have not tolerated other therapies.
Targretin® gel 1% is contraindicated in patients with a known hypersensitivity to bexarotene or other components of the product.
Targretin® gel 1% may cause fetal harm when administered to a pregnant woman.
Targretin® gel must not be given to a pregnant woman or a woman who intends to become pregnant. If a woman becomes pregnant while taking Targretin® gel, Targretin® gel must be stopped immediately and the woman given appropriate counseling.
Bexarotene caused malformations when administered orally to pregnant rats during days 7-17 of gestation. Developmental abnormalities included incomplete ossification at 4 mg/kg/day and cleft palate, depressed eye bulge/microphthalmia, and small ears at 16 mg/kg/day. At doses greater than 10 mg/kg/day, bexarotene caused developmental mortality. The no-effect oral dose in rats was 1 mg/kg/day. Plasma bexarotene concentrations in patients with CTCL applying Targretin® gel 1% were generally less than one hundredth the Cmax associated with dysmorphogenesis in rats, although some patients had Cmax levels that were approximately one eighth the concentration associated with dysmorphogenesis in rats.
Women of child-bearing potential should be advised to avoid becoming pregnant when Targretin® gel is used. The possibility that a woman of child-bearing potential is pregnant at the time therapy is instituted should be considered. A negative pregnancy test (e.g., serum beta-human chorionic gonadotropin, beta-HCG) with a sensitivity of at least 50 mIU/L should be obtained within one week prior to Targretin® gel therapy, and the pregnancy test must be repeated at monthly intervals while the patient remains on Targretin® gel. Effective contraception must be used for one month prior to the initiation of therapy, during therapy and for at least one month following discontinuation of therapy; it is recommended that two reliable forms of contraception be used simultaneously unless abstinence is the chosen method. Male patients with sexual partners who are pregnant, possibly pregnant, or who could become pregnant must use condoms during sexual intercourse while applying Targretin® gel and for at least one month after the last dose of drug. Targretin® gel therapy should be initiated on the second or third day of a normal menstrual period. No more than a one month supply of Targretin® gel should be given to the patient so that the results of pregnancy testing can be assessed and counseling regarding avoidance of pregnancy and birth defects can be reinforced.
General: Targretin® gel should be used with caution in patients with a known hypersensitivity to other retinoids. No clinical instances of cross-reactivity have been noted.
Vitamin A Supplementation: In clinical studies, patients were advised to limit vitamin A intake to≤15,000 IU/day. Because of the relationship of bexarotene to vitamin A, patients should be advised to limit vitamin A supplements to avoid potential additive toxic effects.
Photosensitivity: Retinoids as a class have been associated with photosensitivity. In vitro assays indicate that bexarotene is a potential photosensitizing agent. There were no reports of photosensitivity in patients in the clinical studies. Patients should be advised to minimize exposure to sunlight and artificial ultraviolet light during the use of Targretin® gel.
Patients who are applying Targretin® gel should not concurrently use products that contain DEET (N,N-diethyl-m-toluamide), a common component of insect repellent products. An animal toxicology study showed increased DEET toxicity when DEET was included as part of the formulation.
No formal studies to evaluate drug interactions with bexarotene have been conducted. Bexarotene oxidative metabolites appear to be formed through cytochrome P450 3A4.
On the basis of the metabolism of bexarotene by cytochrome P450 3A4, concomitant ketoconazole, itraconazole, erythromycin and grapefruit juice could increase bexarotene plasma concentrations. Similarly, based on data that gemfibrozil increases bexarotene concentrations following oral bexarotene administration, concomitant gemfibrozil could increase bexarotene plasma concentrations. However, due to the low systemic exposure to bexarotene after low to moderately intense gel regimens (see Clinical Pharmacology), increases that occur are unlikely to be of sufficient magnitude to result in adverse effects.
No drug interaction data are available on concomitant administration of Targretin® gel and other CTCL therapies.
No formal studies have been conducted with Targretin® gel in patients with renal insufficiency. Urinary elimination of bexarotene and its known metabolites is a minor excretory pathway for bexarotene (<1% of an orally administered dose), but because renal insufficiency can result in significant protein binding changes, and bexarotene is >99% protein bound, pharmacokinetics may be altered in patients with renal insufficiency.
No specific studies have been conducted with Targretin® gel in patients with hepatic insufficiency. Because less than 1% of the dose of oral bexarotene is excreted in the urine unchanged and there isin vitro evidence of extensive hepatic contribution to bexarotene elimination, hepatic impairment would be expected to lead to greatly decreased clearance.
Bexarotene is highly bound (>99%) to plasma proteins. The plasma proteins to which bexarotene binds have not been elucidated, and the ability of bexarotene to displace drugs bound to plasma proteins and the ability of drugs to displace bexarotene binding have not been studied.
Long-term studies in animals to assess the carcinogenic potential of bexarotene have not been conducted. Bexarotene was not mutagenic to bacteria (Ames assay) or mammalian cells (mouse lymphoma assay). Bexarotene was not clastogenic in vivo (micronucleus test in mice). No formal fertility studies were conducted with bexarotene. Bexarotene caused testicular degeneration when oral doses of 1.5 mg/kg/day were given to dogs for 91 days.
It is not known whether bexarotene is excreted in human milk. Because many drugs are excreted in human milk and because of the potential for serious adverse reactions in nursing infants from bexarotene, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
Of the total patients with CTCL in clinical studies of Targretin® gel, 62% were under 65 years and 38% were 65 years or older. No overall differences in safety were observed between patients 65 years of age or older and younger patients, but greater sensitivity of some older individuals to Targretin® gel cannot be ruled out. Responses to Targretin® gel were observed across all age group decades, without preference for any individual age group decade.
The safety of Targretin® gel has been assessed in clinical studies of 117 patients with CTCL who received Targretin® gel for up to 172 weeks. In the multicenter open label study, 50 patients with CTCL received Targretin® gel for up to 98 weeks. The mean duration of therapy for these 50 patients was 199 days. The most common adverse events reported with an incidence at the application site of at least 10% in patients with CTCL were rash, pruritus, skin disorder, and pain.
Adverse events leading to dose reduction or study drug discontinuation in at least two patients were rash, contact dermatitis, and pruritus.
Of the 49 patients (98%) who experienced any adverse event, most experienced events categorized as mild (9 patients, 18%) or moderate (27 patients, 54%). There were 12 patients (24%) who experienced at least one moderately severe adverse event. The most common moderately severe events were rash (7 patients, 14%) and pruritus (3 patients, 6%). Only one patient (2%) experienced a severe adverse event (rash).
In the patients with CTCL receiving Targretin® gel, adverse events reported regardless of relationship to study drug at an incidence of ≥5% are presented in Table 1.
A similar safety profile for Targretin® gel was demonstrated in the Phase I-II program. For the 67 patients enrolled in the Phase I-II program, the mean duration of treatment was 436 days (range 12-1203 days). As in the multicenter study, the most common adverse events regardless of relationship to study drug in the Phase I-II program were rash (78%), pain (40%), and pruritus (40%).
| All Adverse Events | Application Site Adverse Events | |
|---|---|---|
| COSTART 5 Body System/Preferred Term |
N = 50 n (%) |
N = 50 n (%) |
|
* Regardless of association with treatment Includes Investigator terms such as: 1 Contact dermatitis, irritant contact dermatitis, irritant dermatitis 2 Pruritus, itching, itching of lesion 3 Erythema, scaling, irritation, redness, rash, dermatitis 4 Skin inflammation, excoriation, sticky or tacky sensation of skin; NOS = Not Otherwise Specified | ||
Skin and Appendages |
||
Contact Dermatitis1 |
7 (14) |
4 (8) |
Exfoliative Dermatitis |
3 (6) |
0 |
Pruritus2 |
18 (36) |
9 (18) |
Rash3 |
36 (72) |
28 (56) |
Maculopapular Rash |
3 (6) |
0 |
Skin Disorder (NOS)4 |
13 (26) |
9 (18) |
Sweating |
3 (6) |
0 |
Body as a Whole |
||
Asthenia |
3 (6) |
0 |
Headache |
7 (14) |
0 |
Infection |
9 (18) |
0 |
Pain |
15 (30) |
9 (18) |
Cardiovascular |
||
Edema |
5 (10) |
0 |
Peripheral Edema |
3 (6) |
0 |
Hemic and Lymphatic |
||
Leukopenia |
3 (6) |
0 |
Lymphadenopathy |
3 (6) |
0 |
WBC Abnormal |
3 (6) |
0 |
Metabolic and Nutritional |
||
Hyperlipemia |
5 (10) |
0 |
Nervous |
||
Paresthesia |
3 (6) |
3 (6) |
Respiratory |
||
Cough Increased |
3 (6) |
0 |
Pharyngitis |
3 (6) |
0 |
Systemic toxicity following acute overdosage with topical application of Targretin® gel is unlikely because of low systemic plasma levels observed with normal therapeutic doses. There is no specific antidote for overdosage.
There has been no experience with acute overdose of Targretin® gel in humans. Any overdose with Targretin® gel should be treated with supportive care for the signs and symptoms exhibited by the patient.
Targretin® gel should be initially applied once every other day for the first week. The application frequency should be increased at weekly intervals to once daily, then twice daily, then three times daily and finally four times daily according to individual lesion tolerance. Generally, patients were able to maintain a dosing frequency of two to four times per day. Most responses were seen at dosing frequencies of two times per day and higher. If application site toxicity occurs, the application frequency can be reduced. Should severe irritation occur, application of drug can be temporarily discontinued for a few days until the symptoms subside. See CONTRAINDICATIONS: Pregnancy: Category X.
Sufficient gel should be applied to cover the lesion with a generous coating. The gel should be allowed to dry before covering with clothing. Because unaffected skin may become irritated, application of the gel to normal skin surrounding the lesions should be avoided. In addition, do not apply the gel near mucosal surfaces of the body.
A response may be seen as soon as 4 weeks after initiation of therapy but most patients require longer application. With continued application, further benefit may be attained. The longest onset time for the first response among the responders was 392 days based on the Composite Assessment of Index Lesion Severity in the multicenter study. In clinical trials, Targretin® gel was applied for up to 172 weeks.
Targretin® gel should be continued as long as the patient is deriving benefit.
Occlusive dressings should not be used with Targretin® gel.
Targretin® gel is a topical therapy and is not intended for systemic use. Targretin® gel has not been studied in combination with other CTCL therapies.
Targretin® gel is supplied in tubes containing 60 g (600 mg active bexarotene).
60 g tube ............................................................................................. NDC 64365-504-01
Store at 25°C (77°F); with excursions permitted to 15°-30°C (59°-86°F) [see USP]. Avoid exposing to high temperatures and humidity after the tube is opened. Protect from light.
Manufactured for: Ligand Pharmaceuticals Incorporated
San
Diego, CA 92121
by: Bristol-Myers Squibb Company
Princeton, NJ 08543 USA
Ligand Part #3000204 (Rev. 0101)
|
TARGRETIN
bexarotene gel | |||||||||||||||
| |||||||||||||||
| |||||||||||||||
| |||||||||||||||
| |||||||||||||||
| Labeler - Ligand Pharmaceuticals Inc. |


|
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Gettysburg's computer science program can prepare you for any career where clear and logical thinking are valued. Our courses contain the technical aspects of computer science, but they also give equal attention to helping students communicate clearly and learn the independence necessary to carry an algorithmic way of thought into their future work, whether it be graduate study, a related discipline, or any career that values critical thinking. Most students find that a major in computer science consists of more than just going to the required classes. There are numerous possibilities for involvement including colloquia and seminars, programming contests, department employment, and research opportunities. More information about the Computer Science department can be found on Gettysburg College's official departmental website. Other pages on this site...
|
Glatfelter Hall: Home of Computer Science. |
|
Department of Computer Science 300 North Washington St. Campus Box 402 Gettysburg, PA 17325 |
Phone:<PHONE_NUMBER> Fax:<PHONE_NUMBER> E-mail<EMAIL_ADDRESS>|


At Princeton, the current pen-and-paper system for monitoring meal exchanges between eating clubs is inconvenient for everyone involved. Members don't know how many meal exchanges they have outstanding with their friends and club administrators spend hours manually tabulating meal exchanges at the end of each month. We're proposing a system where instead of using paper slips, students simply register their meal exchanges and guest meals online on our webapp. Students can receive updates on how many meal exchanges they have outstanding as well as how many guest meals they have left in the month. Eating clubs can edit memberships and club preferences, as well as view all exchanges online or by downloading a .csv file with all the computations done for them. Fewer lost slips of paper, fewer outstanding meal exchanges, fewer hours of manual tabulation. Everyone's a winner!
TutorialsTo register a meal exchange login to your club account and select meal exchange from the options provided on the home page.
This will redirect you to a page that looks like this. Enter the netID of the member under Host netID and the netID of the person they would like to meal exchange with under Guest netID.
If the meal exchange was successful you will be sent to the following thank you page. Both the member and the guest will recieve a confirmation link in an email from<EMAIL_ADDRESS>For the meal exchange to be recorded both parties must click through the link to verify the exchange.
To register a guest meal login to your club account and select guest meal from the options provided on the home page.
This will redirect you to a page that looks like this. Enter the netID of the member under Host netID.
If you have sufficient guest meals left you will be sent to the following thank you page. If not you will be sent to an error page. The member will recieve a confirmation link in an email from<EMAIL_ADDRESS>For the guest meal to be recorded the host must click through the link to verify the guest meal.
To view completed exchanges press the hamburger button on the right hand side and select View Exchanges.
This will take you to a page that looks like this. You can sort the exchanges by clicking on any of the blue table headers. You can also search for all exchanges for a given member by entering their netID in the search field in the upper left corner.
To download all exchanges from this month and last month click Download .csv. This will output an excel file with a list of your members and all the completed meal exchanges.
To view incomplete exchanges press the hamburger button on the right hand side and select View Exchanges.
This will take you to a page that looks like this. Click on View Unconfirmed exchanges.
You will be redirected to the following page. Just like the View Exchanges page you can sort by any of the table headers and search for a specific member's unconfirmed exchanges using the search field in the upper left corner. You can also download a .csv with the confirmed exchanges and a list of members. To go back to View Exchanges click on the right-most button View Exchanges.
If you have not yet set your club preferences you will automatically be redirected to do so. In club preferences you set your meal hours and the number of guest meals each member can have. This allows us to prevent members from trying to meal exchange outside of meal hours and stop members from using more guests than they are alotted. If you would like to edit your preferences click on the hamburger button and select Club Preferences.
This will take you to a page that looks like this. You can reset your preferences whenever you like provided you are logged into your account. Make sure to hit save before leaving this page.
To add or remove members click on the hamburger button and select Edit Membership.
This will take you to a page that looks like this. You can delete members by either individually selecting the checkboxes next to their name and pressing Delete or by searching for a common attribute, i.e. 2016, and pressing Delete All. To add members click Add Members.
To add members click Add Members. This will redirect you to the following page. We allow you to add members by class year. To do this ;ist all the names, first and last , in the top field and the corresponding netIDs in the bottom field. Make sure these are in the same order. Then select their class year and click Submit.
To send reminder emails press the hamburger button on the right hand side and select View Exchanges.
This will take you to a page that looks like this.
Each member with outstanding or incomplete exchanges will recieve an email that looks like this.
To create an account select Register from the options below the login.
You will be redirected to the following page. Once you've inputted your details you will recieve a confirmation link in your email which you need to click through. Once you've done this you're good to go!
"This system has been far overdue. - Lucia Perasso, Terrace President
"Wow I can't believe this hasn't existed all along. It's a game changer!" - Reed Tan, Terrace Treasurer
"I'm really excited to see an app like this, the meal exchange system has been unnecessarily inefficient for way too long. As someone who has been fined unfairly in the past, I'm really looking forward to this new system which will undoubtedly save time and money for both students and eating clubs." - Rose Lapp, Tower member
"Wow I can't believe this hasn't existed all along. It's a game changer!" - Reed Tan, Terrace Treasurer
This app just makes total sense. The process is currently unnecessarily tedious.. this app will make meal exchange simple, logical and painless - so we can all spend more time with our friends! - Nick Stead, Tower Member
Top


Contact Guest Services for any help with the Keys To Elisium App or the Restort.
New Elysium’s host and social manager. He oversees the hosting staff, such asthose working in lounges and restaurants. Tall for a halfling, Filip dresses well in dark business attire or formal wear, sometimes of unusual subtle hues.
The physician who supervises New Elysium’s spa and medical facilities. She’s second to Filip Kallsner when it comes to managerial authority. The doctor is usually wearing a light-colored lab coat over business attire in neutral shades, wearing her dark hair pinned back.
A retired
Xenowarden, oversees care for Green Fields and New Elysium’s other flora. Vori wraps her willowy frame in robes and often leaves her
long silver hair loose or tied in a bun.
New Elysium’s security specialist, commands the resort’s security squads and starship patrols. He is fit and looks the part of a proper, groomed military officer.
Alerts & Notifications: ON
Tutorial and Guidance: ON
Blocked Users: None


@* * Copyright 2023 HM Revenue & Customs * * Licensed under the Apache License, Version 2.0 (the "License"); * you may not use this file except in compliance with the License. * You may obtain a copy of the License at * * http://www.apache.org/licenses/LICENSE-2.0 * * Unless required by applicable law or agreed to in writing, software * distributed under the License is distributed on an "AS IS" BASIS, * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied. * See the License for the specific language governing permissions and * limitations under the License. *@ @import config.AppConfig @import uk.gov.hmrc.webchat.client.WebChatClient @import views.html.templates.MainTemplate @this( main_template: MainTemplate, appConfig: AppConfig, webChatClient: WebChatClient) @()(implicit request: Request[_], messages: play.api.i18n.Messages) @main_template(title = messages("payment.problems.title")) {
@messages("payment.problems.p1")
@messages("payment.problems.p2")
@messages("global.opening.times.title")
@messages("global.opening.times.8to4")
@messages("global.opening.times.weekend.p")
@messages("payment.problems.p3")
@messages("payment.problems.p4")
@messages("payment.problems.p5")
@messages("payment.problems.p6")
}


CluBCpG
0.3.0
User Guide Contents:
1. Getting Started
2. Using CluBCpG
3. Understanding the CluBCpG output data
4. Using CluBCpG with PReLIM
Developer Reference:
API documentation
CluBCpG
Index
Index
Symbols
|
_
|
A
|
B
|
C
|
E
|
F
|
G
|
I
|
L
|
M
|
P
|
R
|
S
|
T
Symbols
--bin_size
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
--bins
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
--chromosome
clubcpg-coverage command line option
clugcpg-impute-coverage command line option
--chunksize
clubcpg-impute-cluster command line option
--cluster_member_minimum
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
--coverage
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--help
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--input_bam_A
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
--input_bam_B
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
--input_bam_file
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--limit_samples
clubcpg-impute-train command line option
--models
clugcpg-impute-coverage command line option
--models_A
clubcpg-impute-cluster command line option
--models_B
clubcpg-impute-cluster command line option
--no_overlap
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
--num_processors
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
--output
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--output_dir
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
--permute
clubcpg-cluster command line option
--read1_3
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--read1_5
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--read2_3
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--read2_5
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
--read_depth
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
--remove_noise
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
--suffix
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
-a
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
-b
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
-c
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
-chr
clubcpg-coverage command line option
clugcpg-impute-coverage command line option
-h
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
-l
clubcpg-impute-train command line option
-m
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
clugcpg-impute-coverage command line option
-n
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
-o
clubcpg-cluster command line option
clubcpg-coverage command line option
clubcpg-impute-cluster command line option
clubcpg-impute-train command line option
clugcpg-impute-coverage command line option
-r
clubcpg-cluster command line option
clubcpg-impute-cluster command line option
_
__init__() (clubcpg.CalculateBinCoverage.CalculateCompleteBins method)
(clubcpg.ClusterReads.ClusterReads method)
(clubcpg.ClusterReads.ClusterReadsWithImputation method)
(clubcpg.ConnectToCpGNet.TrainWithPReLIM method)
(clubcpg.Imputation.Imputation method)
(clubcpg.ParseBam.BamFileReadParser method)
(clubcpg_prelim.PReLIM.CpGBin method)
(clubcpg_prelim.PReLIM.PReLIM method)
A
analyze_bins() (clubcpg.CalculateBinCoverage.CalculateCompleteBins method)
attempt_cpg_position_correction() (clubcpg.ClusterReads.ClusterReads static method)
B
BamFileReadParser (class in clubcpg.ParseBam)
C
calculate_bin_coverage() (clubcpg.CalculateBinCoverage.CalculateCompleteBins method)
CalculateCompleteBins (class in clubcpg.CalculateBinCoverage)
clubcpg-cluster command line option
--bin_size
--bins
--cluster_member_minimum
--help
--input_bam_A
--input_bam_B
--no_overlap
--num_processors
--output_dir
--permute
--read1_3
--read1_5
--read2_3
--read2_5
--read_depth
--remove_noise
--suffix
-a
-b
-h
-m
-n
-o
-r
clubcpg-coverage command line option
--bin_size
--chromosome
--help
--input_bam_A
--no_overlap
--num_processors
--output_dir
--read1_3
--read1_5
--read2_3
--read2_5
-a
-chr
-h
-n
-o
clubcpg-impute-cluster command line option
--bin_size
--bins
--chunksize
--cluster_member_minimum
--help
--input_bam_A
--input_bam_B
--models_A
--models_B
--no_overlap
--num_processors
--output_dir
--read1_3
--read1_5
--read2_3
--read2_5
--read_depth
--remove_noise
--suffix
-a
-b
-h
-m
-n
-o
-r
clubcpg-impute-train command line option
--coverage
--help
--input_bam_file
--limit_samples
--output
--read1_3
--read1_5
--read2_3
--read2_5
-a
-c
-h
-l
-n
-o
clubcpg.CalculateBinCoverage
module
clubcpg.ClusterReads
module
clubcpg.ConnectToCpGNet
module
clubcpg.Imputation
module
clubcpg.ParseBam
module
clubcpg_prelim.PReLIM
module
clugcpg-impute-coverage command line option
--chromosome
--coverage
--help
--input_bam_file
--models
--output
--read1_3
--read1_5
--read2_3
--read2_5
-a
-c
-chr
-h
-m
-n
-o
ClusterReads (class in clubcpg.ClusterReads)
ClusterReadsWithImputation (class in clubcpg.ClusterReads)
correct_cpg_positions() (clubcpg.ParseBam.BamFileReadParser static method)
CpGBin (class in clubcpg_prelim.PReLIM)
create_matrix() (clubcpg.ParseBam.BamFileReadParser method)
E
execute() (clubcpg.ClusterReads.ClusterReads method)
(clubcpg.ClusterReads.ClusterReadsWithImputation method)
extract_matrices() (clubcpg.Imputation.Imputation method)
F
filter_data_frame() (clubcpg.ClusterReads.ClusterReads method)
fit() (clubcpg_prelim.PReLIM.PReLIM method)
fix_read_overlap() (clubcpg.ParseBam.BamFileReadParser method)
G
generate_bins_list() (clubcpg.CalculateBinCoverage.CalculateCompleteBins method)
generate_individual_matrix_data() (clubcpg.ClusterReads.ClusterReads method)
get_chromosome_lengths() (clubcpg.CalculateBinCoverage.CalculateCompleteBins method)
I
Imputation (class in clubcpg.Imputation)
impute() (clubcpg_prelim.PReLIM.PReLIM method)
impute_from_model() (clubcpg.Imputation.Imputation method)
impute_many() (clubcpg_prelim.PReLIM.PReLIM method)
L
loadWeights() (clubcpg_prelim.PReLIM.PReLIM method)
M
module
clubcpg.CalculateBinCoverage
clubcpg.ClusterReads
clubcpg.ConnectToCpGNet
clubcpg.Imputation
clubcpg.ParseBam
clubcpg_prelim.PReLIM
P
parse_reads() (clubcpg.ParseBam.BamFileReadParser method)
postprocess_predictions() (clubcpg.Imputation.Imputation static method)
predict() (clubcpg_prelim.PReLIM.PReLIM method)
predict_classes() (clubcpg_prelim.PReLIM.PReLIM method)
predict_proba() (clubcpg_prelim.PReLIM.PReLIM method)
PReLIM (class in clubcpg_prelim.PReLIM)
process_bins() (clubcpg.ClusterReads.ClusterReads method)
R
remove_scaffolds() (clubcpg.CalculateBinCoverage.CalculateCompleteBins static method)
S
save_net() (clubcpg.ConnectToCpGNet.TrainWithPReLIM method)
T
train() (clubcpg_prelim.PReLIM.PReLIM method)
train_model() (clubcpg.ConnectToCpGNet.TrainWithPReLIM method)
(clubcpg.Imputation.Imputation method)
TrainWithPReLIM (class in clubcpg.ConnectToCpGNet)


In this tutorial, we will cover:
- How to Retrain the state-of-the-art Inception Model's Final Layer for Image Classification.
- How to Retrain a more efficient model "MobileNet's" Final Layer for mobile Phones.
- How to use these models in an Android App and Build it ro use on your phones.
Requirements
- OS: Ubuntu/AWS Cloud/Google Cloud/Windows
- Python 3+
- OpenCV [optional]
- Tensorflow
So, let's get started.
Prerequisites
Data Collection and Preprocessing
The first step in this tutorial before even retraining the model is the collection of the dataset. In this tutorial, I'll be creating my own dataset of "roses" and "tulips". Feel free to collect/use your own dataset.
NOTE: If you want to download a dataset from anywhere else, you can skip this step and move to the first step in this tutorial
To get the images for the dataset, I'll be using Imagenet website to get the links to the images and fetch them using their URL's and a simple python script. So, let's get started.
Let's go the Imagenet website and search for images of roses.
As we can see that for a search of word "rose", Imagenet gives us a lot of results. But here we are focusing only on the flower rose and nothing else. So, the results in the yellow box are the only ones of our interest.
Let's click on the first link and see what we get.
As you can see, we are presented with a lot of images of roses. Now, we want all these images to be in a folder from where we can fetch them and train our network. So, how do we fetch all these images? Well, we write a python script that can fetch all the URL's for each of these images and saves all the images into the folder. Let's see how this works.
On this same page, click on downloads. You will be presented with a link for URL's as shown in image below.
On this page, click on URL's and you will be taken to another page where you will be presented with a lot of URL's. These all URL's are the URL's for each one of the images that we saw earlier and a lot more.
Now, the next step is to fetch all these URL's and download the images from them into a folder using a Python script. So, let's write this python code.
Now that we have fetched all the images of roses and tulips into the 'rose/' and 'tulip/' directories, now it's time to train the upper layers of Inception and MobileNet models.
NOTE: If you think that the amount of data you have downloaded is less, use Imagenet website to get the extra webpage links of other images and use the same script to dowload the images into the same folders.
Retraining the Inception Model [Final Layer]
Inception is a state-of-the-art Image Recognition and Classification model created by Google. Inception model has the following structure:
The Inception model learns different features at every step from the input image and at the output gives the probability of the labels for the contents in the image using a Softmax function on the Logits.
The Inception model consists of a number of deep onvolutional layers. Each convolutional layer learns a different parameter from the image for example the first layer learns the horzontal lines, the second layer learns the vertical lines and so on. Then it uses backtracking to update the weights and the filter parameters and eventually it is able to learn the parameters wrt each class image.
For our use case, we just need to retrain the final layer of the inception model and can use the rest of the model as it is. The retraining will be done on the new images that we have just downloaded i.e. the roses and the tulips.
So, let's get started. To retrain the final layer of the inception model, Google provides us with a "retrain.py" script that we will use as is out of the box. For this, download/clone the tensorflow repository from here.
The python script can be found at the path "tensorflow/tensorflow/examples/image_retraining/retrain.py".
NOTE: The retraining using this script is a bit resource intensive. So, to reduce time, either use a good laptop with a GPU and GPU version of Tensorflow installed or use Google Cloud/AWS. I'll be using Google Cloud for this tutorial.
Now, once you have downloaded this repository, go inside the path mentioned above to access the "retrain.py" and "label.py". We will be using the retrain.py script to retrain the top layer of the inception model and the label.py to test out our trained saved model.
Now, to the main part. The retraining for our dataset. Let's get started !!!
- Using command prompt, go inside the "tensorflow" folder.
- Make a folder and place the "rose" and "tulip" folders containing the images into that folder. After this, the directory should look something like this:
- Now, from inside the tensorflow directory, type the following command:
python3 tensorflow/examples/image_retraining/retrain.py /
--image_dir ~/dataset/ --learning_rate=0.0001 /
--testing_percentage=20 --validation_percentage=20 /
--train_batch_size=32 --validation_batch_size=-1 /
--flip_left_right True --random_scale=30 /
--random_brightness=30 --eval_step_interval=100 /
--how_many_training_steps=600 --architecture inception_v3
So, what are all these variables and values in this command ? Let's see.
The first thing in this is the retraining script. This script defines all the inputs it can take. These are the values that follow in the command. Next, provide the path to the directory which contains the folders containing the images. Learning Rate defines the rate at which the Cost is reduced in the Gradient Curve. If this value is too large, we might overshoot the minima thereby getting less accuracy and more error. If the value is too small, it might take the model too long to reach the minima and hence might take too long.
Then we have the "testing_percentage". This defines that what percentage of the input images will be used as the test data from the original database. "Validation Percentage" defines the percentage of data to be kept aside for validation. The difference between Validation and test data is that we use the validation dataset to improve and fine tune the parameters like the learning rate, weights and bias values to improve the accuracy of the model. Once we are satisfied with the accuracy, then we use the test images to test the model on images that it has not seen before and see how well it performs.
"Train Batch Size" defines the number of images that the model takes as input at once. It is better to input the images in batches as compared to all the images at once as it is good for running on systems with less memory. "Validation Batch Size"
So, now we have reached the end of Part 1 of this tutorial. I hope I was able to clearly represent the working of GAN's.
For a deeper insight into GAN's watch this video and read these two papers: Paper 1 and Paper 2.
For Part 2 of this tutorial, click here
For more projects and code, follow me on Github
Please feel free to leave any comments, suggestions, corrections if any :)
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[gecode-users] Ranking Custom Propagator
Christian Schulte
cschulte at kth.se
Wed May 6 11:56:28 CEST 2009
Hi,
There is no possibility to guarantee order of execution for propagators. What you can do, however, is to give it a very high cost. Then the system will most likely run the propagator later than those with low cost.
Christian
--
Christian Schulte, www.ict.kth.se/~cschulte/
From: users-bounces at gecode.org [mailto:users-bounces at gecode.org] On Behalf Of Debdeep Banerjee
Sent: Wednesday, May 06, 2009 11:30 AM
To: users at gecode.org
Subject: [gecode-users] Ranking Custom Propagator
hi,
I want to execute my custom propagator after all other propagators. How can I do that?
With regards
Debdeep
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--- layout: archive permalink: /hazumi/ title: "Hazumi" author_profile: true ---
springboard by day and diary by night for my budding startup, HAZUMI
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| 039:021 Khan | : |
See you not, that Allah sends down water (rain) from the sky, and causes it to penetrate the earth, (and then makes it to spring up) as water-springs and afterward thereby produces crops of different colours, and afterward they wither and you see them turn yellow, then He makes them dry and broken pieces. Verily, in this, is a Reminder for men of understanding. |
| 039:021 Maulana | : |
Seest thou not that Allah sends down water from the clouds, then makes it go down into the earth in springs, then brings forth therewith herbage of various hues; then it withers so that thou seest it turn yellow, then He makes it chaff? Surely there is a reminder in this for men of understanding. |
| 039:021 Pickthal | : |
Hast thou not seen how Allah hath sent down water from the sky and hath caused it to penetrate the earth as watersprings, and afterward thereby produceth crops of divers hues; and afterward they wither and thou seest them turn yellow; then He maketh them chaff. Lo! herein verily is a reminder for men of understanding. |
| 039:021 Rashad | : |
Do you not see that GOD sends down from the sky water, then places it into underground wells, then produces with it plants of various colors, then they grow until they turn yellow, then He turns them into hay? This should be a reminder for those who possess intelligence. |
| 039:021 Sarwar | : |
Have you not seen that God has sent down water from the sky and made it flow as springs out of the earth? He makes crops of different colors grow with this water and flourish, which then turn yellow and wither away. In this there is a reminder for the people of understanding. |
| 039:021 Shakir | : |
Do you not see that Allah sends down water from the cloud, then makes it go along in the earth in springs, then brings forth therewith herbage of various colors, then it withers so that you see it becoming yellow, then He makes it a thing crushed and broken into pieces? Most surely there is a reminder in this for the men of understanding. |
| 039:021 Sherali | : |
Hast thou not seen that ALLAH sends down water from the sky, and causes it to flow in springs in the earth and then brings forth thereby herbage of diverse hues? Then it dries up and thou seest it turn to yellow; then HE reduces it to broken straw. In that, verily, is a reminder for men of understanding. |
| 039:021 Yusufali | : |
Seest thou not that Allah sends down rain from the sky, and leads it through springs in the earth? Then He causes to grow, therewith, produce of various colours: then it withers; thou wilt see it grow yellow; then He makes it dry up and crumble away. Truly, in this, is a Message of remembrance to men of understanding. |
Concepts/Themes Covered: أركان الإسلام > التوحيد > توحيد الله تعالي > وحدانيته Pillars of Islam> Islamic> Oneness of Allah> Singularity and Being Unique العلوم والفنون > الحقائق العلمية و الإشاة إلى وقائع أيدتهاالإكتشافات العلمية > الغيث Science and Art> The Scientific Facts and the Indication to Facts which have been supported by the Scientific Discoveries>The Rain
This tool uses eight English parallel translations for the Holy Quran imported from Mr. Clay Smith. You can also visit Qurany Concepts for browsing the Quran themes or topics. If you want to search the Holy Quran for keywords, please visit Qurany Keywords.