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4465
11004058
[ { "id": "4466", "type": "document", "text": [ "The effect of systemic lidocaine on pain and secondary hyperalgesia associated with the heat/capsaicin sensitization model in healthy volunteers . UNLABELLED Although effective in neuropathic pain , the efficacy of systemic lidocaine in non-neuropathi...
[ { "id": "4467", "type": "Intervention_Pharmacological", "text": [ "lidocaine" ], "offsets": [ [ 23, 32 ] ], "normalized": [] }, { "id": "4468", "type": "Intervention_Pharmacological", "text": [ "lidocaine" ], "offsets": [ ...
[]
[]
[]
4494
11013280
[ { "id": "4495", "type": "document", "text": [ "Phase III comparative study of high-dose cisplatin versus a combination of paclitaxel and cisplatin in patients with advanced non-small-cell lung cancer . PURPOSE New effective chemotherapy is needed to improve the outcome of patients with advanced no...
[ { "id": "4496", "type": "Intervention_Pharmacological", "text": [ "high-dose cisplatin" ], "offsets": [ [ 31, 50 ] ], "normalized": [] }, { "id": "4497", "type": "Intervention_Pharmacological", "text": [ "paclitaxel and cisplatin" ...
[]
[]
[]
4519
11013281
[ { "id": "4520", "type": "document", "text": [ "Treatment of brain metastases of small-cell lung cancer : comparing teniposide and teniposide with whole-brain radiotherapy -- a phase III study of the European Organization for the Research and Treatment of Cancer Lung Cancer Cooperative Group . PURP...
[ { "id": "4521", "type": "Intervention_Pharmacological", "text": [ "teniposide" ], "offsets": [ [ 68, 78 ] ], "normalized": [] }, { "id": "4522", "type": "Intervention_Pharmacological", "text": [ "teniposide" ], "offsets": [ ...
[]
[]
[]
4548
11013775
[ { "id": "4549", "type": "document", "text": [ "[ Effectiveness of morphine by periarticular injections after shoulder arthroscopy ] . Peripheral opioid receptors have been found in inflamed synovia and the analgesic effect of intra-articularly administered morphine after arthroscopic knee surgery ...
[ { "id": "4550", "type": "Intervention_Pharmacological", "text": [ "morphine" ], "offsets": [ [ 19, 27 ] ], "normalized": [] }, { "id": "4551", "type": "Intervention_Pharmacological", "text": [ "morphine" ], "offsets": [ ...
[]
[]
[]
4566
11015817
[ { "id": "4567", "type": "document", "text": [ "Cost-effectiveness of clozapine compared with conventional antipsychotic medication for patients in state hospitals . BACKGROUND An open-label , randomized controlled trial compared clozapine with physicians'-choice medications among long-term state h...
[ { "id": "4568", "type": "Intervention_Pharmacological", "text": [ "clozapine" ], "offsets": [ [ 22, 31 ] ], "normalized": [] }, { "id": "4569", "type": "Intervention_Pharmacological", "text": [ "clozapine" ], "offsets": [ ...
[]
[]
[]
4593
11021553
[ { "id": "4594", "type": "document", "text": [ "Beta radiation as an adjunct to low-risk trabeculectomy . PURPOSE To assess a single dose of intraoperative beta radiation used to enhance the success rate of trabeculectomy in a population of low-risk glaucoma patients in whom antimetabolites might n...
[ { "id": "4595", "type": "Intervention_Physical", "text": [ "Beta radiation" ], "offsets": [ [ 0, 14 ] ], "normalized": [] }, { "id": "4596", "type": "Intervention_Physical", "text": [ "intraoperative beta radiation" ], "offs...
[]
[]
[]
4609
11022066
[ { "id": "4610", "type": "document", "text": [ "Outcomes of early endovascular versus surgical treatment of ruptured cerebral aneurysms . A prospective randomized study . BACKGROUND AND PURPOSE This prospective study was conducted to compare the outcomes of surgical clipping and endovascular treatm...
[ { "id": "4611", "type": "Intervention_Surgical", "text": [ "surgical treatment" ], "offsets": [ [ 38, 56 ] ], "normalized": [] }, { "id": "4612", "type": "Intervention_Surgical", "text": [ "surgical clipping and endovascular treatme...
[]
[]
[]
4636
11028492
[ { "id": "4637", "type": "document", "text": [ "Short- and long-term results after thrombolytic treatment of deep venous thrombosis . OBJECTIVES The goal of this study was to assess the short- and long-term efficacy of different thrombolytic therapy regimens in patients with leg or pelvic deep veno...
[ { "id": "4638", "type": "Intervention_Control", "text": [ "thrombolytic treatment" ], "offsets": [ [ 35, 57 ] ], "normalized": [] }, { "id": "4639", "type": "Intervention_Physical", "text": [ "thrombolytic therapy" ], "offse...
[]
[]
[]
4654
11029345
[ { "id": "4655", "type": "document", "text": [ "Tromethamine buffer modifies the depressant effect of permissive hypercapnia on myocardial contractility in patients with acute respiratory distress syndrome . In patients with acute respiratory distress syndrome ( ARDS ) , permissive hypercapnia is a...
[ { "id": "4656", "type": "Intervention_Pharmacological", "text": [ "Tromethamine buffer" ], "offsets": [ [ 0, 19 ] ], "normalized": [] }, { "id": "4657", "type": "Intervention_Pharmacological", "text": [ "tromethamine ( THAM )" ]...
[]
[]
[]
4671
11029568
[ { "id": "4672", "type": "document", "text": [ "Epidural fentanyl-bupivacaine compared with clonidine-bupivacaine for analgesia in labour . Alpha-adrenergic agonists produce pain relief through an opioid independent mechanism and may be alternatives to opioids for combination with local anaesthetic...
[ { "id": "4673", "type": "Intervention_Pharmacological", "text": [ "Epidural fentanyl-bupivacaine" ], "offsets": [ [ 0, 29 ] ], "normalized": [] }, { "id": "4674", "type": "Intervention_Pharmacological", "text": [ "clonidine-bupivaca...
[]
[]
[]
4696
11034038
[ { "id": "4697", "type": "document", "text": [ "Randomized , placebo-controlled trial of oral phytonadione for excessive anticoagulation . STUDY OBJECTIVE To compare the efficacy of managing excessive anticoagulation in the absence of bleeding by either omitting warfarin therapy alone or administer...
[ { "id": "4698", "type": "Intervention_Pharmacological", "text": [ "phytonadione" ], "offsets": [ [ 46, 58 ] ], "normalized": [] }, { "id": "4699", "type": "Intervention_Pharmacological", "text": [ "phytonadione" ], "offsets"...
[]
[]
[]
4714
11034934
[ { "id": "4715", "type": "document", "text": [ "VLDL , apolipoproteins B , CIII , and E , and risk of recurrent coronary events in the Cholesterol and Recurrent Events ( CARE ) trial . BACKGROUND Plasma triglyceride concentration has been an inconsistent independent risk factor for coronary heart d...
[ { "id": "4716", "type": "Intervention_Control", "text": [ "placebo-controlled" ], "offsets": [ [ 522, 540 ] ], "normalized": [] }, { "id": "4717", "type": "Intervention_Pharmacological", "text": [ "pravastatin" ], "offsets":...
[]
[]
[]
4747
11041498
[ { "id": "4748", "type": "document", "text": [ "An evaluation of chemical arthrodesis of the proximal interphalangeal joint in the horse by using monoiodoacetate . The use of monoiodoacetate ( MIA ) for arthrodesis of the proximal interphalangeal joint ( PIJ ) and the effect of exercise on the degr...
[ { "id": "4749", "type": "Intervention_Pharmacological", "text": [ "monoiodoacetate" ], "offsets": [ [ 98, 113 ] ], "normalized": [] }, { "id": "4750", "type": "Intervention_Pharmacological", "text": [ "monoiodoacetate ( MIA )" ]...
[]
[]
[]
4767
11045790
[ { "id": "4768", "type": "document", "text": [ "Randomized trial of fenretinide in superficial bladder cancer using DNA flow cytometry as an intermediate end point . Retinoids have shown a potential activity in preventing tumor recurrence in superficial bladder cancer . We assessed the activity of ...
[ { "id": "4769", "type": "Intervention_Pharmacological", "text": [ "fenretinide" ], "offsets": [ [ 20, 31 ] ], "normalized": [] }, { "id": "4770", "type": "Intervention_Pharmacological", "text": [ "synthetic retinoid fenretinide" ...
[]
[]
[]
4784
11053333
[ { "id": "4785", "type": "document", "text": [ "Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans . An acute bout of aerobic exercise results in a reduced blood pressure that lasts several hours . Animal studies suggest this response is mediated by increased ...
[ { "id": "4786", "type": "Intervention_Pharmacological", "text": [ "nitric oxide synthase" ], "offsets": [ [ 19, 40 ] ], "normalized": [] }, { "id": "4787", "type": "Intervention_Physical", "text": [ "( 60 min of seated upright rest"...
[]
[]
[]
4799
11056245
[ { "id": "4800", "type": "document", "text": [ "Depressive mood symptoms associated with ovarian suppression . OBJECTIVE To determine if sertraline is helpful in the management of depressive symptoms associated with ovarian suppression during GnRH agonist therapy as compared with a placebo-controll...
[ { "id": "4801", "type": "Intervention_Pharmacological", "text": [ "sertraline" ], "offsets": [ [ 89, 99 ] ], "normalized": [] }, { "id": "4802", "type": "Intervention_Pharmacological", "text": [ "GnRH agonist therapy" ], "of...
[]
[]
[]
4816
11056317
[ { "id": "4817", "type": "document", "text": [ "Update on tamoxifen to prevent breast cancer . The Italian Tamoxifen Prevention Study ." ], "offsets": [ [ 0, 87 ] ] } ]
[ { "id": "4818", "type": "Intervention_Pharmacological", "text": [ "tamoxifen" ], "offsets": [ [ 10, 19 ] ], "normalized": [] }, { "id": "4819", "type": "Intervention_Pharmacological", "text": [ "Tamoxifen" ], "offsets": [ ...
[]
[]
[]
4822
11056593
[ { "id": "4823", "type": "document", "text": [ "Efficacy and safety of recombinant human nerve growth factor in patients with diabetic polyneuropathy : A randomized controlled trial . rhNGF Clinical Investigator Group . CONTEXT Nerve growth factor is a neurotrophic factor that promotes the survival...
[ { "id": "4824", "type": "Intervention_Physical", "text": [ "recombinant human nerve growth factor" ], "offsets": [ [ 23, 60 ] ], "normalized": [] }, { "id": "4825", "type": "Intervention_Physical", "text": [ "Recombinant human nerve...
[]
[]
[]
4851
11060324
[ { "id": "4852", "type": "document", "text": [ "Commentary on \" cytoreduction nephrectomy in metastatic renal cancer : the results of Southwest Oncology Group Trial 8949 \" ." ], "offsets": [ [ 0, 125 ] ] } ]
[ { "id": "4853", "type": "Intervention_Surgical", "text": [ "cytoreduction nephrectomy" ], "offsets": [ [ 16, 41 ] ], "normalized": [] }, { "id": "4854", "type": "Participant_Condition", "text": [ "\" cytoreduction nephrectomy in met...
[]
[]
[]
4856
11064610
[ { "id": "4857", "type": "document", "text": [ "Comparison of alfentanil , fentanyl and sufentanil for total intravenous anaesthesia with propofol in patients undergoing coronary artery bypass surgery . We have studied the pharmacokinetics and pharmacodynamics of alfentanil , fentanyl and sufentani...
[ { "id": "4858", "type": "Intervention_Pharmacological", "text": [ "alfentanil" ], "offsets": [ [ 14, 24 ] ], "normalized": [] }, { "id": "4859", "type": "Intervention_Pharmacological", "text": [ "fentanyl" ], "offsets": [ ...
[]
[]
[]
4902
11068835
[ { "id": "4903", "type": "document", "text": [ "Magnetic resonance angiography for monitoring prophylactic endoscopic treatment of high risk esophageal varices . BACKGROUND AND STUDY AIMS Endoscopic injection sclerotherapy ( EIS ) and endoscopic variceal ligation ( EVL ) are used worldwide as the t...
[ { "id": "4904", "type": "Intervention_Pharmacological", "text": [ "Endoscopic injection sclerotherapy ( EIS )" ], "offsets": [ [ 140, 182 ] ], "normalized": [] }, { "id": "4905", "type": "Intervention_Surgical", "text": [ "endoscopi...
[]
[]
[]
4918
11069570
[ { "id": "4919", "type": "document", "text": [ "Probiotics in the management of atopic eczema . BACKGROUND Over the last two decades the incidence of allergic diseases has increased in industrialized countries , and consequently new approaches have to be explored . OBJECTIVE The potential of probio...
[ { "id": "4920", "type": "Intervention_Pharmacological", "text": [ "Probiotics" ], "offsets": [ [ 0, 10 ] ], "normalized": [] }, { "id": "4921", "type": "Intervention_Pharmacological", "text": [ "probiotic-supplemented" ], "o...
[]
[]
[]
4935
11072681
[ { "id": "4936", "type": "document", "text": [ "[ New therapeutic approaches in irritable bowel syndrome ] ." ], "offsets": [ [ 0, 60 ] ] } ]
[ { "id": "4937", "type": "Intervention_Pharmacological", "text": [ "New therapeutic approaches" ], "offsets": [ [ 2, 28 ] ], "normalized": [] }, { "id": "4938", "type": "Participant_Condition", "text": [ "irritable bowel syndrome" ...
[]
[]
[]
4939
11073017
[ { "id": "4940", "type": "document", "text": [ "Calcium and fibre supplementation in prevention of colorectal adenoma recurrence : a randomised intervention trial . European Cancer Prevention Organisation Study Group . BACKGROUND Some epidemiological studies have suggested that high dietary intake ...
[ { "id": "4941", "type": "Intervention_Pharmacological", "text": [ "Calcium and fibre supplementation" ], "offsets": [ [ 0, 33 ] ], "normalized": [] }, { "id": "4942", "type": "Intervention_Pharmacological", "text": [ "calcium" ]...
[]
[]
[]
4970
11074150
[ { "id": "4971", "type": "document", "text": [ "Effects of nicotine on regional cerebral glucose metabolism in awake resting tobacco smokers . Eleven healthy tobacco smoking adult male volunteers of mixed race were tobacco abstinent overnight for this study . In each subject , positron emission tom...
[ { "id": "4972", "type": "Intervention_Pharmacological", "text": [ "nicotine" ], "offsets": [ [ 11, 19 ] ], "normalized": [] }, { "id": "4973", "type": "Intervention_Physical", "text": [ "tobacco abstinent" ], "offsets": [ ...
[]
[]
[]
4989
11077389
[ { "id": "4990", "type": "document", "text": [ "Effect of systemic penicillin on pain in untreated irreversible pulpitis . OBJECTIVE The purpose of this prospective , randomized , double-blind study was to determine the effect of penicillin on pain in untreated teeth diagnosed with irreversible pul...
[ { "id": "4991", "type": "Intervention_Pharmacological", "text": [ "systemic penicillin" ], "offsets": [ [ 10, 29 ] ], "normalized": [] }, { "id": "4992", "type": "Intervention_Pharmacological", "text": [ "penicillin" ], "off...
[]
[]
[]
5008
11098982
[ { "id": "5009", "type": "document", "text": [ "Percutaneous tracheostomy in critically ill patients : a prospective , randomized comparison of two techniques . OBJECTIVE To prospectively compare two commonly used methods for percutaneous dilational tracheostomy ( PDT ) in critically ill patients ....
[ { "id": "5010", "type": "Intervention_Surgical", "text": [ "percutaneous dilational tracheostomy ( PDT )" ], "offsets": [ [ 178, 222 ] ], "normalized": [] }, { "id": "5011", "type": "Intervention_Surgical", "text": [ "PDT" ], ...
[]
[]
[]
5035
11100343
[ { "id": "5036", "type": "document", "text": [ "Somatostatin and ranitidine in the treatment of non-variceal upper gastrointestinal bleeding : a prospective , randomized , double-blind , controlled study . BACKGROUND/AIMS The aim of this study was to compare the efficacy of somatostatin vs. ranitid...
[ { "id": "5037", "type": "Intervention_Pharmacological", "text": [ "Somatostatin and ranitidine" ], "offsets": [ [ 0, 27 ] ], "normalized": [] }, { "id": "5038", "type": "Intervention_Pharmacological", "text": [ "somatostatin vs. ran...
[]
[]
[]
5058
11104595
[ { "id": "5059", "type": "document", "text": [ "Perioperative enteral nutrition and quality of life of severely malnourished head and neck cancer patients : a randomized clinical trial . BACKGROUND AND AIMS This study evaluated the use of perioperative nutritional support on Quality of Life ( QOL )...
[ { "id": "5060", "type": "Intervention_Physical", "text": [ "perioperative nutritional support" ], "offsets": [ [ 191, 224 ] ], "normalized": [] }, { "id": "5061", "type": "Intervention_Physical", "text": [ "no preoperative and stand...
[]
[]
[]
5080
11106679
[ { "id": "5081", "type": "document", "text": [ "Chemoprevention of gastric dysplasia : randomized trial of antioxidant supplements and anti-helicobacter pylori therapy . BACKGROUND Previous research has identified a high risk of gastric carcinoma as well as a high prevalence of cancer precursor les...
[ { "id": "5082", "type": "Intervention_Pharmacological", "text": [ "antioxidant supplements and anti-helicobacter pylori therapy ." ], "offsets": [ [ 59, 121 ] ], "normalized": [] }, { "id": "5083", "type": "Participant_Condition", "text":...
[]
[]
[]
5088
11108177
[ { "id": "5089", "type": "document", "text": [ "Measurement of peptidase activity and evaluation of effectiveness of administration of minocycline for treatment of dogs with periodontitis . OBJECTIVE To determine clinical , enzymatic , and microbiologic effects of controlled-release localized admin...
[ { "id": "5090", "type": "Intervention_Pharmacological", "text": [ "minocycline" ], "offsets": [ [ 87, 98 ] ], "normalized": [] }, { "id": "5091", "type": "Intervention_Pharmacological", "text": [ "minocycline" ], "offsets": ...
[]
[]
[]
5119
11132252
[ { "id": "5120", "type": "document", "text": [ "Effect of secretin on children with autism : a randomized controlled trial . To determine the effect of intravenous porcine secretin on autistic behaviours in children aged 2 to 7 years , the effects of secretin on ( 1 ) performance on a standardized ...
[ { "id": "5121", "type": "Intervention_Pharmacological", "text": [ "secretin" ], "offsets": [ [ 10, 18 ] ], "normalized": [] }, { "id": "5122", "type": "Intervention_Pharmacological", "text": [ "intravenous porcine secretin" ], ...
[]
[]
[]
5132
11134799
[ { "id": "5133", "type": "document", "text": [ "A randomized trial in simultaneous pancreas-kidney transplantation : portal versus systemic venous drainage of the pancreas allograft ." ], "offsets": [ [ 0, 135 ] ] } ]
[ { "id": "5134", "type": "Intervention_Surgical", "text": [ "pancreas-kidney transplantation" ], "offsets": [ [ 35, 66 ] ], "normalized": [] }, { "id": "5135", "type": "Intervention_Surgical", "text": [ "portal versus systemic venous...
[]
[]
[]
5138
11136837
[ { "id": "5139", "type": "document", "text": [ "Cardiovascular effects of tamoxifen in women with and without heart disease : breast cancer prevention trial . National Surgical Adjuvant Breast and Bowel Project Breast Cancer Prevention Trial Investigators . BACKGROUND The overall effect of prophyla...
[ { "id": "5140", "type": "Intervention_Pharmacological", "text": [ "tamoxifen" ], "offsets": [ [ 26, 35 ] ], "normalized": [] }, { "id": "5141", "type": "Intervention_Pharmacological", "text": [ "tamoxifen ( 20 mg/day )" ], "...
[]
[]
[]
5163
11140546
[ { "id": "5164", "type": "document", "text": [ "Do heavier women benefit from a higher dose of leuprolide acetate for suppression of serum estradiol ? OBJECTIVE To determine if heavier women benefit from a higher dose of the gonadotropin-releasing hormone analogue leuprolide acetate ( LA ) depot in...
[ { "id": "5165", "type": "Intervention_Pharmacological", "text": [ "leuprolide acetate" ], "offsets": [ [ 47, 65 ] ], "normalized": [] }, { "id": "5166", "type": "Intervention_Pharmacological", "text": [ "gonadotropin-releasing hormo...
[]
[]
[]
5185
11154142
[ { "id": "5186", "type": "document", "text": [ "Unopposed estrogen increases total plasma factor VII , but not active factor VII -- a short-term placebo-controlled study in healthy postmenopausal women . Estrogen therapy may increase the risk of arterial thromboembolism , at least in the short term...
[ { "id": "5187", "type": "Intervention_Pharmacological", "text": [ "Unopposed estrogen" ], "offsets": [ [ 0, 18 ] ], "normalized": [] }, { "id": "5188", "type": "Intervention_Control", "text": [ "placebo-controlled" ], "offse...
[]
[]
[]
5209
11156811
[ { "id": "5210", "type": "document", "text": [ "Sertraline treatment of generalized social phobia : a 20-week , double-blind , placebo-controlled study . OBJECTIVE The authors evaluated the efficacy , safety , and tolerability of sertraline , a selective serotonin reuptake inhibitor , in the treatm...
[ { "id": "5211", "type": "Intervention_Pharmacological", "text": [ "Sertraline" ], "offsets": [ [ 0, 10 ] ], "normalized": [] }, { "id": "5212", "type": "Intervention_Pharmacological", "text": [ "sertraline" ], "offsets": [ ...
[]
[]
[]
5242
11157143
[ { "id": "5243", "type": "document", "text": [ "The effects of treatment with interleukin-1 receptor antagonist on the inflamed synovial membrane in rheumatoid arthritis . OBJECTIVE To evaluate the effects of treatment with interleukin-1 receptor antagonist ( IL-1Ra ) on synovial tissue in rheumato...
[ { "id": "5244", "type": "Intervention_Pharmacological", "text": [ "interleukin-1 receptor antagonist" ], "offsets": [ [ 30, 63 ] ], "normalized": [] }, { "id": "5245", "type": "Intervention_Pharmacological", "text": [ "interleukin-1...
[]
[]
[]
5263
11159256
[ { "id": "5264", "type": "document", "text": [ "The response of neuropathic pain and pain in complex regional pain syndrome I to carbamazepine and sustained-release morphine in patients pretreated with spinal cord stimulation : a double-blinded randomized study . Forty-three patients with periphera...
[ { "id": "5265", "type": "Intervention_Pharmacological", "text": [ "carbamazepine" ], "offsets": [ [ 81, 94 ] ], "normalized": [] }, { "id": "5266", "type": "Intervention_Pharmacological", "text": [ "sustained-release morphine" ]...
[]
[]
[]
5290
11162323
[ { "id": "5291", "type": "document", "text": [ "Counselor and stimulus control enhancements of a stage-matched expert system intervention for smokers in a managed care setting . BACKGROUND Previous research has demonstrated the efficacy of an interactive expert system intervention for smoking cessa...
[ { "id": "5292", "type": "Intervention_Educational", "text": [ "stage-matched expert system intervention" ], "offsets": [ [ 49, 89 ] ], "normalized": [] }, { "id": "5293", "type": "Intervention_Educational", "text": [ "interactive ex...
[]
[]
[]
5312
11167879
[ { "id": "5313", "type": "document", "text": [ "Perioperative blood transfusions , with or without allogeneic leucocytes , relate to survival , not to cancer recurrence . BACKGROUND Perioperative blood transfusions are reported to be related to cancer recurrence and reduced survival . Different und...
[ { "id": "5314", "type": "Intervention_Pharmacological", "text": [ "Perioperative blood transfusions , with or without allogeneic leucocytes" ], "offsets": [ [ 0, 72 ] ], "normalized": [] }, { "id": "5315", "type": "Intervention_Pharmacologica...
[]
[]
[]
5334
11191952
[ { "id": "5335", "type": "document", "text": [ "[ Diphtheria antitoxin level 2 years after booster vaccination ] . In a prospective , controlled , randomized , multicenter study the immunogenicity of a single ( day 0 ) and two ( day 0 , 28 ) booster vaccination against diphtheria were compared in s...
[ { "id": "5336", "type": "Intervention_Pharmacological", "text": [ "booster vaccination" ], "offsets": [ [ 43, 62 ] ], "normalized": [] }, { "id": "5337", "type": "Intervention_Pharmacological", "text": [ "booster vaccination against...
[]
[]
[]
5350
11194696
[ { "id": "5351", "type": "document", "text": [ "Increasing the reach of health sponsorship : using a \" sponsorship kit \" to promote health . In Australia , a tobacco tax provides funding for Healthway , the Western Australian Health Promotion Foundation . Healthway provides sponsorships for the a...
[ { "id": "5352", "type": "Intervention_Educational", "text": [ "sponsor kit of promotional materials" ], "offsets": [ [ 619, 655 ] ], "normalized": [] }, { "id": "5353", "type": "Intervention_Educational", "text": [ "sponsorship kits...
[]
[]
[]
5356
11196013
[ { "id": "5357", "type": "document", "text": [ "Spatial orientation adjustments in children with autism in Hong Kong . Abnormal spatial orientation and body postures in children with autism often interfere with visual abilities to attend tasks and social interactions . Twenty-four children diagnose...
[ { "id": "5358", "type": "Intervention_Other", "text": [ "Spatial orientation adjustments" ], "offsets": [ [ 0, 31 ] ], "normalized": [] }, { "id": "5359", "type": "Intervention_Physical", "text": [ "wore" ], "offsets": [ ...
[]
[]
[]
5377
11196396
[ { "id": "5378", "type": "document", "text": [ "Comparison of the efficacy of fluoxetine alone vs. fluoxetine plus local lidocaine ointment in the treatment of premature ejaculation . OBJECTIVE The present study compares the efficacy and side effects of fluoxetine alone vs. fluoxetine plus local li...
[ { "id": "5379", "type": "Intervention_Pharmacological", "text": [ "fluoxetine alone" ], "offsets": [ [ 30, 46 ] ], "normalized": [] }, { "id": "5380", "type": "Intervention_Pharmacological", "text": [ "fluoxetine" ], "offset...
[]
[]
[]
5404
1119679
[ { "id": "5405", "type": "document", "text": [ "The injured colon : therapeutic considerations . A prospective randomized study was carried out at the Detroit General Hospital over a two year period to evaluate methods of management in 165 patients with colonic injuries . Results of the study show ...
[ { "id": "5406", "type": "Intervention_Physical", "text": [ "colonic injuries" ], "offsets": [ [ 206, 222 ] ], "normalized": [] }, { "id": "5407", "type": "Intervention_Physical", "text": [ "primary closure" ], "offsets": [ ...
[]
[]
[]
5421
11199239
[ { "id": "5422", "type": "document", "text": [ "Is hands-on experience more effective than didactic workshops in postgraduate cancer pain education ? BACKGROUND This study examined the nurse outcomes of a cancer pain education program for nurses of patients from 11 different ethnic groups . METHODS...
[ { "id": "5423", "type": "Intervention_Educational", "text": [ "one-day workshop or two half-day workshops" ], "offsets": [ [ 331, 373 ] ], "normalized": [] }, { "id": "5424", "type": "Intervention_Educational", "text": [ "cancer pai...
[]
[]
[]
5435
11205419
[ { "id": "5436", "type": "document", "text": [ "Cognitive performance and serotonergic function in users of ecstasy . RATIONALE ( +/- ) 3,4-Methylenedioxymethamphetamine ( MDMA or \" ecstasy \" ) has been shown to cause long term damage to serotonergic cerebral neurons in animals . The neurotoxic e...
[ { "id": "5437", "type": "Intervention_Pharmacological", "text": [ "3,4-Methylenedioxymethamphetamine ( MDMA or \" ecstasy \" )" ], "offsets": [ [ 88, 145 ] ], "normalized": [] }, { "id": "5438", "type": "Intervention_Pharmacological", "te...
[]
[]
[]
5458
11207836
[ { "id": "5459", "type": "document", "text": [ "The effect of aging on circulating levels of proinflammatory cytokines during septic shock . Norasept II Study Investigators . BACKGROUND As the proportion of the population that is older continues to rise , infection in older people has become an imp...
[ { "id": "5460", "type": "Intervention_Pharmacological", "text": [ "Norasept II" ], "offsets": [ [ 93, 104 ] ], "normalized": [] }, { "id": "5461", "type": "Intervention_Control", "text": [ "placebo" ], "offsets": [ [ ...
[]
[]
[]
5499
11208371
[ { "id": "5500", "type": "document", "text": [ "Effect of surgical technique in subtotal and bilateral thyroidectomy on risk of postoperative parathyroid insufficiency development -- our experience . One of the postoperative complications after strumectomy is hypoparathyroidism . Therefore , the pu...
[ { "id": "5501", "type": "Intervention_Surgical", "text": [ "surgical technique" ], "offsets": [ [ 10, 28 ] ], "normalized": [] }, { "id": "5502", "type": "Intervention_Surgical", "text": [ "subtotal and bilateral thyroidectomy" ...
[]
[]
[]
5514
11210885
[ { "id": "5515", "type": "document", "text": [ "Alternative voice after laryngectomy using a sound-producing voice prosthesis . OBJECTIVE To improve the voice quality of female laryngectomees and/or laryngectomees with a hypotonic pharyngoesophageal ( PE ) segment by means of a pneumatic artificial...
[ { "id": "5516", "type": "Intervention_Physical", "text": [ "laryngectomy" ], "offsets": [ [ 24, 36 ] ], "normalized": [] }, { "id": "5517", "type": "Intervention_Other", "text": [ "sound-producing voice prosthesis" ], "offse...
[]
[]
[]
5540
11213870
[ { "id": "5541", "type": "document", "text": [ "Beneficial effects of a soy-based dietary supplement on lipid levels and cardiovascular risk markers in type 2 diabetic subjects . OBJECTIVE Consumption of soy protein has recently been shown to improve the blood lipid levels in nondiabetic subjects ....
[ { "id": "5542", "type": "Intervention_Pharmacological", "text": [ "soy-based dietary supplement" ], "offsets": [ [ 24, 52 ] ], "normalized": [] }, { "id": "5543", "type": "Intervention_Pharmacological", "text": [ "soy protein" ]...
[]
[]
[]
5580
11214014
[ { "id": "5581", "type": "document", "text": [ "Effect of allopurinol on myocardial oxygen free radical production in coronary bypass surgery . OBJECTIVES Allopurinol protects the heart from reperfusion injury . The aim of this study was to investigate myocardial free radical production during repe...
[ { "id": "5582", "type": "Intervention_Pharmacological", "text": [ "allopurinol" ], "offsets": [ [ 10, 21 ] ], "normalized": [] }, { "id": "5583", "type": "Intervention_Pharmacological", "text": [ "Allopurinol" ], "offsets": ...
[]
[]
[]
5598
11218508
[ { "id": "5599", "type": "document", "text": [ "The effect of splinting of teeth in combination with reconstructive periodontal surgery in humans . The purpose of this study was to evaluate the effect of splinting teeth on the results of periodontal reconstructive surgery using a specific carbonate...
[ { "id": "5600", "type": "Intervention_Physical", "text": [ "splinting of teeth" ], "offsets": [ [ 14, 32 ] ], "normalized": [] }, { "id": "5601", "type": "Intervention_Surgical", "text": [ "reconstructive periodontal surgery" ],...
[]
[]
[]
5625
11219757
[ { "id": "5626", "type": "document", "text": [ "Simplified subjective workload assessment technique . Although the subjective workload assessment technique ( SWAT ) has been widely used , it has two main problems : it is not very sensitive for low mental workloads and it requires a time-consuming c...
[ { "id": "5627", "type": "Intervention_Educational", "text": [ "Simplified subjective workload assessment technique ." ], "offsets": [ [ 0, 53 ] ], "normalized": [] }, { "id": "5628", "type": "Intervention_Educational", "text": [ "su...
[]
[]
[]
5642
11228756
[ { "id": "5643", "type": "document", "text": [ "Effect of acarbose on additional insulin therapy in type 2 diabetic patients with late failure of sulphonylurea therapy . AIM The present study investigated the effect of acarbose on insulin requirements and glycaemic control in patients with type 2 d...
[ { "id": "5644", "type": "Intervention_Pharmacological", "text": [ "acarbose" ], "offsets": [ [ 10, 18 ] ], "normalized": [] }, { "id": "5645", "type": "Intervention_Pharmacological", "text": [ "insulin therapy" ], "offsets":...
[]
[]
[]
5688
11234566
[ { "id": "5689", "type": "document", "text": [ "Phase-dependent modulation of the soleus H-reflex during rhythmical arm swing in humans . The purpose of this study is to investigate modulation of the soleus H-reflex during rhythmic arm swing in humans . Significant depression of the soleus H-reflex...
[ { "id": "5690", "type": "Intervention_Physical", "text": [ "rhythmical arm swing" ], "offsets": [ [ 57, 77 ] ], "normalized": [] }, { "id": "5691", "type": "Intervention_Physical", "text": [ "soleus H-reflex" ], "offsets": [...
[]
[]
[]
5707
11237545
[ { "id": "5708", "type": "document", "text": [ "Comparison of provocative tests for unexplained syncope : isoprenaline and glyceryl trinitrate for diagnosing vasovagal syncope . AIMS To compare the sensitivity , specificity and adverse event profile of glyceryl trinitrate head-up tilt with isoprena...
[ { "id": "5709", "type": "Intervention_Pharmacological", "text": [ "isoprenaline" ], "offsets": [ [ 58, 70 ] ], "normalized": [] }, { "id": "5710", "type": "Intervention_Pharmacological", "text": [ "glyceryl trinitrate" ], "o...
[]
[]
[]
5736
11238483
[ { "id": "5737", "type": "document", "text": [ "Effect of protein ingestion on the glucose appearance rate in people with type 2 diabetes . Amino acids derived from ingested protein are potential substrates for gluconeogenesis . However , several laboratories have reported that protein ingestion do...
[ { "id": "5738", "type": "Intervention_Pharmacological", "text": [ "protein ingestion" ], "offsets": [ [ 10, 27 ] ], "normalized": [] }, { "id": "5739", "type": "Intervention_Pharmacological", "text": [ "50 g" ], "offsets": [...
[]
[]
[]
5762
11246578
[ { "id": "5763", "type": "document", "text": [ "Work-related stress and early atherosclerosis . The purpose of this study was to examine the link between work-related stress and early atherosclerosis as measured by common carotid artery intima-media thickness and focal lesions in the common carotid...
[ { "id": "5764", "type": "Intervention_Psychological", "text": [ "questionnaires" ], "offsets": [ [ 372, 386 ] ], "normalized": [] }, { "id": "5765", "type": "Intervention_Physical", "text": [ "B-mode ultrasound" ], "offsets"...
[]
[]
[]
5780
11253439
[ { "id": "5781", "type": "document", "text": [ "Sun protection behaviors and stages of change for the primary prevention of skin cancers among beachgoers in southeastern New England . Sun exposure is the most important avoidable cause of skin cancers . We report characteristics of a representative ...
[ { "id": "5782", "type": "Intervention_Educational", "text": [ "Sun protection behaviors" ], "offsets": [ [ 0, 24 ] ], "normalized": [] }, { "id": "5783", "type": "Intervention_Educational", "text": [ "sun protection behaviors" ]...
[]
[]
[]
5790
11265037
[ { "id": "5791", "type": "document", "text": [ "RAB-plate versus sliding hip screw for unstable trochanteric hip fractures : stability of the fixation and modes of failure -- radiographic analysis of 218 fractures . BACKGROUND The sliding hip screw has gained considerable acceptance in the treatmen...
[ { "id": "5792", "type": "Intervention_Surgical", "text": [ "RAB-plate" ], "offsets": [ [ 0, 9 ] ], "normalized": [] }, { "id": "5793", "type": "Intervention_Surgical", "text": [ "sliding hip screw" ], "offsets": [ [ ...
[]
[]
[]
5801
11267196
[ { "id": "5802", "type": "document", "text": [ "A single-center open label randomized trial of the safety and efficacy of the use of sirolimus versus azathioprine in one-haplotype living related kidney transplant recipients-preliminary results ." ], "offsets": [ [ 0, 1...
[ { "id": "5803", "type": "Intervention_Pharmacological", "text": [ "sirolimus versus azathioprine" ], "offsets": [ [ 85, 114 ] ], "normalized": [] }, { "id": "5804", "type": "Outcome_Other", "text": [ "safety and efficacy" ], ...
[]
[]
[]
5805
11284463
[ { "id": "5806", "type": "document", "text": [ "Oral rizatriptan versus oral sumatriptan : a direct comparative study in the acute treatment of migraine . Rizatriptan 030 Study Group . Rizatriptan is a potent , oral , 5-HT1B/1D agonist with more rapid absorption and higher bioavailability than oral...
[ { "id": "5807", "type": "Intervention_Pharmacological", "text": [ "rizatriptan 5 mg , rizatriptan 10 mg , sumatriptan 100 mg" ], "offsets": [ [ 418, 475 ] ], "normalized": [] }, { "id": "5808", "type": "Intervention_Control", "text": [ ...
[]
[]
[]
5818
11292273
[ { "id": "5819", "type": "document", "text": [ "Clinical implications of a reduction in psychological distress on cardiac prognosis in patients participating in a psychosocial intervention program . OBJECTIVE The objective of this secondary analysis was to examine the relationships between a reduct...
[ { "id": "5820", "type": "Intervention_Educational", "text": [ "psychosocial intervention program" ], "offsets": [ [ 115, 148 ] ], "normalized": [] }, { "id": "5821", "type": "Intervention_Educational", "text": [ "studied 433 patient...
[]
[]
[]
5844
11292279
[ { "id": "5845", "type": "document", "text": [ "Central nervous system serotonin function and cardiovascular responses to stress . OBJECTIVE The objective of this study was to evaluate the impact of indices of central nervous system ( CNS ) serotonin function on cardiovascular reactivity to mental ...
[ { "id": "5846", "type": "Intervention_Physical", "text": [ "Lumbar puncture" ], "offsets": [ [ 268, 283 ] ], "normalized": [] }, { "id": "5847", "type": "Outcome_Physical", "text": [ "cardiovascular responses" ], "offsets": ...
[]
[]
[]
5856
11295009
[ { "id": "5857", "type": "document", "text": [ "Interferential therapy electrode placement technique in acute low back pain : a preliminary investigation . OBJECTIVE To determine the efficacy of interferential therapy ( IFT ) electrode placement technique compared with a control treatment in subjec...
[ { "id": "5858", "type": "Intervention_Physical", "text": [ "Interferential therapy electrode placement technique" ], "offsets": [ [ 0, 52 ] ], "normalized": [] }, { "id": "5859", "type": "Intervention_Physical", "text": [ "interfere...
[]
[]
[]
5871
11297722
[ { "id": "5872", "type": "document", "text": [ "Double-blind placebo-controlled administration of fluoxetine in restricting- and restricting-purging-type anorexia nervosa . BACKGROUND Anorexia nervosa is an often chronic disorder with high morbidity and mortality . Many people relapse after weight ...
[ { "id": "5873", "type": "Intervention_Control", "text": [ "placebo-controlled" ], "offsets": [ [ 13, 31 ] ], "normalized": [] }, { "id": "5874", "type": "Intervention_Pharmacological", "text": [ "fluoxetine" ], "offsets": [ ...
[]
[]
[]
5890
11300174
[ { "id": "5891", "type": "document", "text": [ "Effectiveness of the school dental screening programme in stimulating dental attendance for children in need of treatment in Northern Ireland . UNLABELLED The school dental screening programme has been in existence from the beginning of the 20th centu...
[ { "id": "5892", "type": "Intervention_Educational", "text": [ "school dental screening programme" ], "offsets": [ [ 21, 54 ] ], "normalized": [] }, { "id": "5893", "type": "Intervention_Educational", "text": [ "school dental screeni...
[]
[]
[]
5912
11302295
[ { "id": "5913", "type": "document", "text": [ "Psychosocial nursing therapy following sudden cardiac arrest : impact on two-year survival . BACKGROUND Although psychosocial therapy has been shown to reduce mortality after myocardial infarction , it is unknown whether the benefits of psychosocial t...
[ { "id": "5914", "type": "Intervention_Psychological", "text": [ "Psychosocial nursing therapy" ], "offsets": [ [ 0, 28 ] ], "normalized": [] }, { "id": "5915", "type": "Intervention_Educational", "text": [ "psychosocial therapy" ...
[]
[]
[]
5938
11305684
[ { "id": "5939", "type": "document", "text": [ "Effectiveness of N , N-dimethylglycine in autism and pervasive developmental disorder . N , N-dimethylglycine , a dietary supplement , has been reported to be beneficial in children with autism and pervasive developmental disorder . We examined the ef...
[ { "id": "5940", "type": "Intervention_Pharmacological", "text": [ "N , N-dimethylglycine" ], "offsets": [ [ 17, 38 ] ], "normalized": [] }, { "id": "5941", "type": "Intervention_Control", "text": [ "receive either placebo" ], ...
[]
[]
[]
5953
11315533
[ { "id": "5954", "type": "document", "text": [ "Children with persistent conduct problems who dropout of treatment . Dropout of treatment is one of the key issues in outcome in a child and adolescent mental health service . We report two studies focusing on the treatment process and the dropout rat...
[ { "id": "5955", "type": "Intervention_Educational", "text": [ "CBT approach with conjoint family therapy and an eclectic approach ." ], "offsets": [ [ 476, 544 ] ], "normalized": [] }, { "id": "5956", "type": "Intervention_Educational", "...
[]
[]
[]
5970
11318022
[ { "id": "5971", "type": "document", "text": [ "Double hearing protection and speech intelligibility-room for improvement . INTRODUCTION Double hearing protection is used in many air forces around the world for protection in noisy aircraft environments , particularly in helicopters . The usual comb...
[ { "id": "5972", "type": "Intervention_Other", "text": [ "an environment of recorded helicopter noise from a BO-105 helicopter" ], "offsets": [ [ 991, 1059 ] ], "normalized": [] }, { "id": "5973", "type": "Intervention_Other", "text": [ ...
[]
[]
[]
5982
11318056
[ { "id": "5983", "type": "document", "text": [ "Variability in isochronous tapping : higher order dependencies as a function of intertap interval . Isochronous serial interval production ( ISIP ) data , as from unpaced finger tapping , exhibit higher order dependencies ( drift ) . This fact has lar...
[ { "id": "5984", "type": "Intervention_Physical", "text": [ "isochronous tapping" ], "offsets": [ [ 15, 34 ] ], "normalized": [] }, { "id": "5985", "type": "Intervention_Physical", "text": [ "unpaced finger tapping" ], "offse...
[]
[]
[]
5992
11319711
[ { "id": "5993", "type": "document", "text": [ "Physiologic modeling of the intravenous glucose tolerance test in type 2 diabetes : a new approach to the insulin compartment . The minimal model of Bergman et al has been used to yield estimates of insulin sensitivity ( Si ) and glucose effectiveness...
[ { "id": "5994", "type": "Intervention_Pharmacological", "text": [ "exogenous insulin protocols" ], "offsets": [ [ 295, 322 ] ], "normalized": [] }, { "id": "5995", "type": "Intervention_Pharmacological", "text": [ "exogenous insulin...
[]
[]
[]
6008
11322670
[ { "id": "6009", "type": "document", "text": [ "A pharmacy discharge plan for hospitalized elderly patients -- a randomized controlled trial . OBJECTIVES to investigate the effectiveness of a pharmacy discharge plan in elderly hospitalized patients . DESIGN randomized controlled trial . SUBJECTS AN...
[ { "id": "6010", "type": "Intervention_Other", "text": [ "pharmacy discharge plan" ], "offsets": [ [ 2, 25 ] ], "normalized": [] }, { "id": "6011", "type": "Intervention_Other", "text": [ "pharmacy discharge" ], "offsets": [ ...
[]
[]
[]
6034
11323998
[ { "id": "6035", "type": "document", "text": [ "Comparative evaluation of calcium hydroxide and zinc oxide eugenol as root canal filling materials for primary molars : a clinical and radiographic study . Calcium hydroxide , a material widely used for the treatment of permanent teeth has not been us...
[ { "id": "6036", "type": "Intervention_Pharmacological", "text": [ "calcium hydroxide" ], "offsets": [ [ 26, 43 ] ], "normalized": [] }, { "id": "6037", "type": "Intervention_Pharmacological", "text": [ "zinc oxide eugenol" ], ...
[]
[]
[]
6048
11331049
[ { "id": "6049", "type": "document", "text": [ "A randomized controlled trial assessing the health economics of realtime teledermatology compared with conventional care : an urban versus rural perspective . A randomized controlled trial was carried out to measure the cost-effectiveness of realtime ...
[ { "id": "6050", "type": "Intervention_Physical", "text": [ "realtime teledermatology" ], "offsets": [ [ 64, 88 ] ], "normalized": [] }, { "id": "6051", "type": "Intervention_Physical", "text": [ "conventional care" ], "offse...
[]
[]
[]
6076
11331721
[ { "id": "6077", "type": "document", "text": [ "Repeated doses of porcine secretin in the treatment of autism : a randomized , placebo-controlled trial . BACKGROUND AND OBJECTIVES Anecdotal reports on the efficacy of secretin in autism raised great hopes for the treatment of children with this diso...
[ { "id": "6078", "type": "Intervention_Pharmacological", "text": [ "porcine secretin" ], "offsets": [ [ 18, 34 ] ], "normalized": [] }, { "id": "6079", "type": "Intervention_Pharmacological", "text": [ "secretin" ], "offsets"...
[]
[]
[]
6102
11334068
[ { "id": "6103", "type": "document", "text": [ "Comments on \" Comparison of gastrointestinal tolerance feeding proctocols in critically ill patients : a prospective , randomized controlled clinical trial \" ." ], "offsets": [ [ 0, 159 ] ] } ]
[ { "id": "6104", "type": "Intervention_Educational", "text": [ "tolerance feeding proctocols" ], "offsets": [ [ 45, 73 ] ], "normalized": [] }, { "id": "6105", "type": "Outcome_Physical", "text": [ "gastrointestinal tolerance" ],...
[]
[]
[]
6108
11343038
[ { "id": "6109", "type": "document", "text": [ "A randomized , double-blind , placebo-controlled trial of single-dose intravenous secretin as treatment for children with autism . OBJECTIVE To determine whether a single injection of intravenous secretin results in measurable improvements in socializ...
[ { "id": "6110", "type": "Intervention_Pharmacological", "text": [ "secretin" ], "offsets": [ [ 82, 90 ] ], "normalized": [] }, { "id": "6111", "type": "Intervention_Pharmacological", "text": [ "secretin" ], "offsets": [ ...
[]
[]
[]
6126
11350502
[ { "id": "6127", "type": "document", "text": [ "Clinical and microbial evaluation of a histatin-containing mouthrinse in humans with experimental gingivitis . OBJECTIVE P-113 , a 12 amino acid histatin-based peptide , was evaluated in a mouthrinse formulation for safety , prevention of the developm...
[ { "id": "6128", "type": "Intervention_Pharmacological", "text": [ "histatin-containing mouthrinse" ], "offsets": [ [ 39, 69 ] ], "normalized": [] }, { "id": "6129", "type": "Intervention_Pharmacological", "text": [ "P-113 , a 12 ami...
[]
[]
[]
6144
11352886
[ { "id": "6145", "type": "document", "text": [ "L-arginine and S-nitrosoglutathione reduce embolization in humans . BACKGROUND L-Arginine reduces platelet aggregation and adhesion in ex vivo studies , but there is no evidence as yet that it has a therapeutic effect on clinical end points . Doppler ...
[ { "id": "6146", "type": "Intervention_Pharmacological", "text": [ "L-arginine" ], "offsets": [ [ 0, 10 ] ], "normalized": [] }, { "id": "6147", "type": "Intervention_Pharmacological", "text": [ "S-nitrosoglutathione" ], "off...
[]
[]
[]
6170
11360574
[ { "id": "6171", "type": "document", "text": [ "[ Clinical and experimental research of Epimedium brevicornum in relieving neuroendocrino-immunological effect inhibited by exogenous glucocorticoid ] . OBJECTIVE To study protective effect of Epimedium brevicornum ( EB ) on hypothalamus-pituitary-adr...
[ { "id": "6172", "type": "Intervention_Pharmacological", "text": [ "Epimedium brevicornum" ], "offsets": [ [ 40, 61 ] ], "normalized": [] }, { "id": "6173", "type": "Intervention_Pharmacological", "text": [ "Epimedium brevicornum ( E...
[]
[]
[]
6188
11362397
[ { "id": "6189", "type": "document", "text": [ "Thalidomide : an alternative therapy for treatment of apthous ulcers ( canker sores ) ." ], "offsets": [ [ 0, 87 ] ] } ]
[ { "id": "6190", "type": "Intervention_Pharmacological", "text": [ "Thalidomide" ], "offsets": [ [ 0, 11 ] ], "normalized": [] }, { "id": "6191", "type": "Outcome_Physical", "text": [ "treatment of apthous ulcers" ], "offsets...
[]
[]
[]
6192
11362629
[ { "id": "6193", "type": "document", "text": [ "\" Confirmatory \" trials : symptom reduction as efficacy measure ." ], "offsets": [ [ 0, 65 ] ] } ]
[ { "id": "6194", "type": "Intervention_Physical", "text": [ "symptom reduction" ], "offsets": [ [ 26, 43 ] ], "normalized": [] }, { "id": "6195", "type": "Outcome_Physical", "text": [ "symptom reduction" ], "offsets": [ ...
[]
[]
[]
6198
11363044
[ { "id": "6199", "type": "document", "text": [ "Peptide T : negative trial result ." ], "offsets": [ [ 0, 35 ] ] } ]
[ { "id": "6200", "type": "Intervention_Pharmacological", "text": [ "Peptide T" ], "offsets": [ [ 0, 9 ] ], "normalized": [] }, { "id": "6201", "type": "Outcome_Physical", "text": [ "Peptide T : negative trial result" ], "offs...
[]
[]
[]
6202
11369627
[ { "id": "6203", "type": "document", "text": [ "Immune reconstitution after allogeneic marrow transplantation compared with blood stem cell transplantation . Allogeneic peripheral blood stem cell grafts contain about 10 times more T and B cells than marrow grafts . Because these cells may survive i...
[ { "id": "6204", "type": "Intervention_Surgical", "text": [ "allogeneic marrow transplantation" ], "offsets": [ [ 28, 61 ] ], "normalized": [] }, { "id": "6205", "type": "Intervention_Surgical", "text": [ "blood stem cell transplanta...
[]
[]
[]
6224
11374137
[ { "id": "6225", "type": "document", "text": [ "[ Advantages of video assisted thoracic surgery in the treatment of spontaneous pneumothorax ] . Spontaneous pneumothorax ( SP ) is a disabling condition mostly affecting young , thin and otherwise healthy males . It is usually caused by ruptured pleu...
[ { "id": "6226", "type": "Intervention_Surgical", "text": [ "video assisted thoracic surgery" ], "offsets": [ [ 16, 47 ] ], "normalized": [] }, { "id": "6227", "type": "Intervention_Surgical", "text": [ "insertion of a chest tube ( I...
[]
[]
[]
6250
11377310
[ { "id": "6251", "type": "document", "text": [ "Effects of irrigation fluid temperature on core body temperature during transurethral resection of the prostate . OBJECTIVES To determine the effect irrigation fluid temperature has on core body temperature changes in patients undergoing transurethral...
[ { "id": "6252", "type": "Intervention_Surgical", "text": [ "transurethral resection" ], "offsets": [ [ 72, 95 ] ], "normalized": [] }, { "id": "6253", "type": "Intervention_Surgical", "text": [ "transurethral resection of the prosta...
[]
[]
[]
6275
11378004
[ { "id": "6276", "type": "document", "text": [ "Carvedilol increases plasma vascular endothelial growth factor ( VEGF ) in patients with chronic heart failure ." ], "offsets": [ [ 0, 112 ] ] } ]
[ { "id": "6277", "type": "Intervention_Pharmacological", "text": [ "Carvedilol" ], "offsets": [ [ 0, 10 ] ], "normalized": [] }, { "id": "6278", "type": "Outcome_Physical", "text": [ "plasma vascular endothelial growth factor ( VEGF ...
[]
[]
[]
6280
11378833
[ { "id": "6281", "type": "document", "text": [ "Dose response effect of cyclical medroxyprogesterone on blood pressure in postmenopausal women . OBJECTIVE This study was designed to compare with placebo the dose-response effect of cyclical doses of the C21 progestogen , medroxyprogesterone acetate ...
[ { "id": "6282", "type": "Intervention_Pharmacological", "text": [ "cyclical medroxyprogesterone" ], "offsets": [ [ 24, 52 ] ], "normalized": [] }, { "id": "6283", "type": "Intervention_Control", "text": [ "placebo" ], "offse...
[]
[]
[]
6306
11379334
[ { "id": "6307", "type": "document", "text": [ "Efficacy and tolerability of antibiotics in patients undergoing H. pylori eradication . BACKGROUND/AIMS Helicobacter pylori ( H. pylori ) infection is one of the most common gastrointestinal diseases . An increasing number of people undergo different ...
[ { "id": "6308", "type": "Intervention_Pharmacological", "text": [ "antibiotics" ], "offsets": [ [ 29, 40 ] ], "normalized": [] }, { "id": "6309", "type": "Intervention_Pharmacological", "text": [ "antibiotics" ], "offsets": ...
[]
[]
[]
6334
11384820
[ { "id": "6335", "type": "document", "text": [ "Rehabilitation outcomes following percutaneous coronary interventions ( PCI ) . This prospective study evaluated the effect of an individualized , comprehensive , home-based cardiac rehabilitation program combining exercise training with risk factor m...
[ { "id": "6336", "type": "Intervention_Educational", "text": [ "post-percutaneous coronary interventions ( PCI )" ], "offsets": [ [ 384, 432 ] ], "normalized": [] }, { "id": "6337", "type": "Intervention_Control", "text": [ "control ...
[]
[]
[]
6353
11392343
[ { "id": "6354", "type": "document", "text": [ "Double-blind , placebo-controlled study of amantadine hydrochloride in the treatment of children with autistic disorder . OBJECTIVE To test the hypothesis that amantadine hydrochloride is a safe and effective treatment for behavioral disturbances -- f...
[ { "id": "6355", "type": "Intervention_Control", "text": [ "placebo-controlled" ], "offsets": [ [ 15, 33 ] ], "normalized": [] }, { "id": "6356", "type": "Intervention_Pharmacological", "text": [ "amantadine hydrochloride" ], ...
[]
[]
[]
6378
11395821
[ { "id": "6379", "type": "document", "text": [ "Laparoscopic vs open appendectomy in overweight patients . BACKGROUND Laparoscopic appendectomy ( LA ) has been associated with a faster recovery and less postoperative pain than the open technique . However , few data are available on the clinical ou...
[ { "id": "6380", "type": "Intervention_Surgical", "text": [ "Laparoscopic" ], "offsets": [ [ 0, 12 ] ], "normalized": [] }, { "id": "6381", "type": "Intervention_Surgical", "text": [ "open appendectomy" ], "offsets": [ ...
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6412
11396751
[ { "id": "6413", "type": "document", "text": [ "A comparative study of caudal bupivacaine and midazolam-bupivacaine mixture for post-operative analgesia in children undergoing genitourinary surgery . OBJECTIVE This study was designed to evaluate the analgesic efficacy of caudal midazolam-bupivacain...
[ { "id": "6414", "type": "Intervention_Pharmacological", "text": [ "caudal bupivacaine and midazolam-bupivacaine mixture" ], "offsets": [ [ 23, 75 ] ], "normalized": [] }, { "id": "6415", "type": "Intervention_Pharmacological", "text": [ ...
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6438
11408369
[ { "id": "6439", "type": "document", "text": [ "In vivo effect of clarithromycin on multiple cytochrome P450s . The in vivo effects of oral clarithromycin administration on the in vivo activity of cytochrome P450 1A2 , 2C9 , and 2D6 were determined . The cytochrome P450 probes caffeine ( CYP1A2 ) ,...
[ { "id": "6440", "type": "Intervention_Pharmacological", "text": [ "clarithromycin" ], "offsets": [ [ 18, 32 ] ], "normalized": [] }, { "id": "6441", "type": "Intervention_Pharmacological", "text": [ "clarithromycin" ], "offs...
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6465
11411192
[ { "id": "6466", "type": "document", "text": [ "Treating the substance-abusing suicidal patient . Studies concerning the treatment of substance-abusing suicidal patients are scarce despite the frequent presence of suicidal behavior among this population . Indeed , suicidality ( ideation or behavior...
[ { "id": "6467", "type": "Intervention_Educational", "text": [ "open-label study" ], "offsets": [ [ 724, 740 ] ], "normalized": [] }, { "id": "6468", "type": "Intervention_Control", "text": [ "placebo" ], "offsets": [ [...
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6499
11413274
[ { "id": "6500", "type": "document", "text": [ "Gabapentin but not vigabatrin is effective in the treatment of acquired nystagmus in multiple sclerosis : How valid is the GABAergic hypothesis ? Acquired nystagmus occurs frequently in patients with multiple sclerosis and is often the cause of illuso...
[ { "id": "6501", "type": "Intervention_Pharmacological", "text": [ "gabapentin ( 1200 mg daily ) or vigabatrin ( 2000 mg daily )" ], "offsets": [ [ 916, 976 ] ], "normalized": [] }, { "id": "6502", "type": "Outcome_Other", "text": [ ...
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